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The map label for this gene is yqeC [H]

Identifier: 77458811

GI number: 77458811

Start: 2963368

End: 2964348

Strand: Direct

Name: yqeC [H]

Synonym: Pfl01_2586

Alternate gene names: 77458811

Gene position: 2963368-2964348 (Clockwise)

Preceding gene: 77458806

Following gene: 77458812

Centisome position: 46.03

GC content: 63.71

Gene sequence:

>981_bases
ATGCAACTCGGGATTATTGGACTGGGCCGCATGGGCGGCAATATTGCGCGACGTCTGATGCTCAACGGTCACACCACCGT
TGTTTACGACCGCAATACCGCCTTTGTCGATACCCTGGCCGCCGAGGGCTCTACCGGCGTCGCCGACCTGCCTGCACTGG
TCGCAGGCCTGGCCAAACCGCGTGCGGTGTGGGTCATGCTGCCGGCCGGCGCACCGACTGAAGACACCATCGAAACCCTG
AGCCATCTGCTCGAGGCGGGCGACACCATCATCGATGGCGGCAACACCAACTACAAGGACGACATCCGTCGGGCCAAGAC
CCTGGCCGAGAAGGGCCTGCACTACATTGATGTCGGCACCTCCGGCGGCGTCTGGGGCCTGGAGCGTGGCTACTGCATGA
TGATCGGCGGTGATGCCGAGACCGTTAAGCGTCTGGACCCGCTGTTCGCCGCGTTGGCGCCGGGCATGGGCGACATCCCG
CGCACCAAGGACCGCAAGTCCGATGACCACCGTGCCGAGCACGGCTACATCCACGCCGGTCCCGCCGGTGCCGGTCACTT
CGTGAAGATGATCCACAACGGGATCGAGTACGGGATGATGGCGGCTTTCGCCGAAGGCTTCGATATTCTCAAGACCAAGT
CCAGCGAGCTCCTGCCGGAAGATCAGCGTTTCGACCTGAACGTGGCCGATATCGCCGAAGTCTGGCGTCGTGGCAGCGTG
GTGTCGTCGTGGCTGCTCGACCTGACCGCCGATGCCCTGGCGGTCGACCCGAAACTCGACGGCTTCTCCGGCTCCGTGGC
CGACAGCGGCGAAGGTCAATGGACCATCGAAGCGGCCATGGAACAAAAGGTGCCGGTACCGGTGCTGTCCAACTCGCTGT
TCTCGCGCTACCGCTCCCGCGGCCAGGGCACTTTCGGCGACAAGATTCTTTCGGCCCAGCGCTTCGGCTTCGGCGGCCAT
GTGGAGACACCGAAGAAATGA

Upstream 100 bases:

>100_bases
ATGCACGGAAACTTCAACCCGACGCTCTGGACTAACCTCCATTAGTCCCGTTGGGCTATACCTTTGACACACTTTTATTT
GTAGTAAGGAGCATCAGCAC

Downstream 100 bases:

>100_bases
CCCATACGATCCGCAGAAAATCCAAGGCAGAACCCGCGCCACCGACCACGCTGTTTCTGTTCGGCGCCCACGGTGATCTG
GTCAAGCGCCTGCTTATGCC

Product: 6-phosphogluconate dehydrogenase-like protein

Products: D-ribulose 5-phosphate; CO2; NADPH

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MQLGIIGLGRMGGNIARRLMLNGHTTVVYDRNTAFVDTLAAEGSTGVADLPALVAGLAKPRAVWVMLPAGAPTEDTIETL
SHLLEAGDTIIDGGNTNYKDDIRRAKTLAEKGLHYIDVGTSGGVWGLERGYCMMIGGDAETVKRLDPLFAALAPGMGDIP
RTKDRKSDDHRAEHGYIHAGPAGAGHFVKMIHNGIEYGMMAAFAEGFDILKTKSSELLPEDQRFDLNVADIAEVWRRGSV
VSSWLLDLTADALAVDPKLDGFSGSVADSGEGQWTIEAAMEQKVPVPVLSNSLFSRYRSRGQGTFGDKILSAQRFGFGGH
VETPKK

Sequences:

>Translated_326_residues
MQLGIIGLGRMGGNIARRLMLNGHTTVVYDRNTAFVDTLAAEGSTGVADLPALVAGLAKPRAVWVMLPAGAPTEDTIETL
SHLLEAGDTIIDGGNTNYKDDIRRAKTLAEKGLHYIDVGTSGGVWGLERGYCMMIGGDAETVKRLDPLFAALAPGMGDIP
RTKDRKSDDHRAEHGYIHAGPAGAGHFVKMIHNGIEYGMMAAFAEGFDILKTKSSELLPEDQRFDLNVADIAEVWRRGSV
VSSWLLDLTADALAVDPKLDGFSGSVADSGEGQWTIEAAMEQKVPVPVLSNSLFSRYRSRGQGTFGDKILSAQRFGFGGH
VETPKK
>Mature_326_residues
MQLGIIGLGRMGGNIARRLMLNGHTTVVYDRNTAFVDTLAAEGSTGVADLPALVAGLAKPRAVWVMLPAGAPTEDTIETL
SHLLEAGDTIIDGGNTNYKDDIRRAKTLAEKGLHYIDVGTSGGVWGLERGYCMMIGGDAETVKRLDPLFAALAPGMGDIP
RTKDRKSDDHRAEHGYIHAGPAGAGHFVKMIHNGIEYGMMAAFAEGFDILKTKSSELLPEDQRFDLNVADIAEVWRRGSV
VSSWLLDLTADALAVDPKLDGFSGSVADSGEGQWTIEAAMEQKVPVPVLSNSLFSRYRSRGQGTFGDKILSAQRFGFGGH
VETPKK

Specific function: May act as NAD-dependent 6-P-gluconate dehydrogenase [H]

COG id: COG1023

COG function: function code G; Predicted 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=332, Percent_Identity=31.3253012048193, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1788341, Length=329, Percent_Identity=32.2188449848024, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17542558, Length=307, Percent_Identity=32.5732899022801, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321695, Length=308, Percent_Identity=33.1168831168831, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6321977, Length=307, Percent_Identity=32.8990228013029, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24639279, Length=306, Percent_Identity=33.9869281045752, Blast_Score=132, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR004849
- InterPro:   IPR006114
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: 1.1.1.44

Molecular weight: Translated: 34955; Mature: 34955

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLGIIGLGRMGGNIARRLMLNGHTTVVYDRNTAFVDTLAAEGSTGVADLPALVAGLAKP
CCEEEEEECCCCHHHHHHHEECCCEEEEEECCCCEEHHHHCCCCCCHHHHHHHHHHCCCC
RAVWVMLPAGAPTEDTIETLSHLLEAGDTIIDGGNTNYKDDIRRAKTLAEKGLHYIDVGT
CEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEECC
SGGVWGLERGYCMMIGGDAETVKRLDPLFAALAPGMGDIPRTKDRKSDDHRAEHGYIHAG
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCEEECC
PAGAGHFVKMIHNGIEYGMMAAFAEGFDILKTKSSELLPEDQRFDLNVADIAEVWRRGSV
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHCCHH
VSSWLLDLTADALAVDPKLDGFSGSVADSGEGQWTIEAAMEQKVPVPVLSNSLFSRYRSR
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHC
GQGTFGDKILSAQRFGFGGHVETPKK
CCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQLGIIGLGRMGGNIARRLMLNGHTTVVYDRNTAFVDTLAAEGSTGVADLPALVAGLAKP
CCEEEEEECCCCHHHHHHHEECCCEEEEEECCCCEEHHHHCCCCCCHHHHHHHHHHCCCC
RAVWVMLPAGAPTEDTIETLSHLLEAGDTIIDGGNTNYKDDIRRAKTLAEKGLHYIDVGT
CEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEECC
SGGVWGLERGYCMMIGGDAETVKRLDPLFAALAPGMGDIPRTKDRKSDDHRAEHGYIHAG
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCEEECC
PAGAGHFVKMIHNGIEYGMMAAFAEGFDILKTKSSELLPEDQRFDLNVADIAEVWRRGSV
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHCCHH
VSSWLLDLTADALAVDPKLDGFSGSVADSGEGQWTIEAAMEQKVPVPVLSNSLFSRYRSR
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHC
GQGTFGDKILSAQRFGFGGHVETPKK
CCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.05 {6-phosphogluconate}} 0.01 {6-phosphogluconate}} [C]

Substrates: 6-phospho-D-gluconate; NADP+

Specific reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]