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The map label for this gene is tolQ [H]

Identifier: 77458723

GI number: 77458723

Start: 2856800

End: 2858599

Strand: Direct

Name: tolQ [H]

Synonym: Pfl01_2498

Alternate gene names: 77458723

Gene position: 2856800-2858599 (Clockwise)

Preceding gene: 77458722

Following gene: 77458724

Centisome position: 44.37

GC content: 64.39

Gene sequence:

>1800_bases
ATGCAGCGCCTATTCCTTTCGTTGTTGATCTGCCTGGGCTTCGTGCTCCCGGCCACGGCTCAAGCCTGGTGGCAGGACGA
CTGGCATTACCGCAAACAGATCGCCGTCGACACCACGCCGCAAGGCGCCGCGATCAATCAGGCCCTGGGCCGCACCGCGC
TGCTGGTGCGCCTGCACACCGGCAACTTCACCTTCGACGGCGTGAAAGAGGACGGCTCGGACCTGCGCTTCGTCGCCGCG
GATGACAAGACCGTGCTCAACCATCAGATCGAAAGCTTCGACGCGCTGATGGGCATGGCGCAGATCTGGGTCGATGTGCC
GAATGTCGAGGGCGGTCAGCGTCAGGACATCTGGATGTACTACGGCAACCAGAAGGCCCCGGCGACCGGCAACGGCCAAC
TGACGTTAGATCCGAATTACACCGCGCTCTATCACTTCGACGGCGCCACCGGTACTCCGGCCAAAGACACCACCGCTTAC
GGCAACACCGCGCAGAGCGCGACCGGCGCCGCGATTGACGGCGTAGTCGGGCGTGCCTTGCAGTTCAGCGGCCAGCCGCT
GCTGCTACCGGCCAGTCCGTCGTTGCAGCACAACGCTGGCAGCGCGTTCACCTTCAGTGCCTGGCTGCGACTGGACCAGG
CCAACGGCGAGCAACTGATCCTGGCCCGCCGCGAAGGCGCCAACAGCCTGCTGGTCGGGGTAAATCAGGGCGTGCCGTTC
GTGGACATCGACGGCCAGCGCGCCGTTGCCACGCAGCCGCTGAATCCGGGCCAATGGCAGCACGTCGCACTGACCGCCGA
AGGCGCAAAAGTGACGCTGTACATCAACGGTCGCGAAAGTGCGGCACTGGCTCAGGCAATGCCGGCGTTCAACTCGGTCA
TGGCTATTGGCGCCGATCTGCACGAAGGTCCTTTCCAACCGTTCGTGGGCGCCATCGATGAACTGCGCCTGTCGAAAGTC
GCCCGTCCGGCGCCGCTGTTGCTGGCTGACGCCACCTCCCAGGGCGCTGAATCGAAACTGGTAGCCTACGGCGTTGATGA
AGAACAGTCCGGCTTCGGTTTCGGCAGCCTCGGCTTCCTGCTCAACGCGGTGCCGGTGGACGCTTGGGTGATCATCGCGG
TGCTGGTGCTGATGATGTTCCAGTCGTGGATCATCATGCTGCGCAAGAACCGCACCCTCAGCCGTGTCACCGCCGCCAAC
GAAGACTTCCGCGTGCAGTTCGCCAAGGTCGGTACTCGCCTGGAAATGTTCGCCGACGACACCCAACTCGCCCAGCGATT
GCAGCACTCGTCGCTGTGGCGCCTGTATCTGGTGGCCGTGAAAGAAATCCGCACCCGCCGCGAGCAGGGCGCCGATACCT
CGTCGGTTTCCGCCGCAACCATCGAAGCGATCCGCTGCTCGATGGACGGCGTGCGCACCCGTGAAAACCAGCAACTGAGC
TCGAAACTCTCGACCCTGTCCAACGCCATCGCCGGCGGCCCGTACATCGGCCTGCTCGGCACGGTGCTGGGGATCATGGT
GGTGTTCCTCGGCACCGCCATGGCCGGCGACGTCAACATCAACGCCATCGCGCCGGGCATGGCGGCCGCGTTGCTGGCCA
CGGCCATGGGTCTGTTCGTCGCGATCCCGGCGCTGTTTGGCTACAACCGCCTGATCACCCGCAACAAGGAAGTCAGCGCC
GACATGCGCGTGTTCGTCGACGAGTTCATCACCCGTCTGGCGGAGATGCACGGCGAAGGCCAGTCCAGTGAAGCGGCGCA
TCAGCGCGGCCATCACGCCAACCAATCCGTACCGGCCTGA

Upstream 100 bases:

>100_bases
TCGACTGGGGCTACCCGCTACTCGAAGGGCCGAACACCTCGAAACAGGAATCGCGCCTGCACTTCAACCTTCAGGCCACT
TTCTAACAGGAGCACTTTTC

Downstream 100 bases:

>100_bases
GGAGCACTGACATGGCGTCCGTAAATGCCTCCCACGACGATGACGAAGATGCCGCAGTGGACAGCATCAACATCACGCCT
CTGGTGGACGTGCTGATGGT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MQRLFLSLLICLGFVLPATAQAWWQDDWHYRKQIAVDTTPQGAAINQALGRTALLVRLHTGNFTFDGVKEDGSDLRFVAA
DDKTVLNHQIESFDALMGMAQIWVDVPNVEGGQRQDIWMYYGNQKAPATGNGQLTLDPNYTALYHFDGATGTPAKDTTAY
GNTAQSATGAAIDGVVGRALQFSGQPLLLPASPSLQHNAGSAFTFSAWLRLDQANGEQLILARREGANSLLVGVNQGVPF
VDIDGQRAVATQPLNPGQWQHVALTAEGAKVTLYINGRESAALAQAMPAFNSVMAIGADLHEGPFQPFVGAIDELRLSKV
ARPAPLLLADATSQGAESKLVAYGVDEEQSGFGFGSLGFLLNAVPVDAWVIIAVLVLMMFQSWIIMLRKNRTLSRVTAAN
EDFRVQFAKVGTRLEMFADDTQLAQRLQHSSLWRLYLVAVKEIRTRREQGADTSSVSAATIEAIRCSMDGVRTRENQQLS
SKLSTLSNAIAGGPYIGLLGTVLGIMVVFLGTAMAGDVNINAIAPGMAAALLATAMGLFVAIPALFGYNRLITRNKEVSA
DMRVFVDEFITRLAEMHGEGQSSEAAHQRGHHANQSVPA

Sequences:

>Translated_599_residues
MQRLFLSLLICLGFVLPATAQAWWQDDWHYRKQIAVDTTPQGAAINQALGRTALLVRLHTGNFTFDGVKEDGSDLRFVAA
DDKTVLNHQIESFDALMGMAQIWVDVPNVEGGQRQDIWMYYGNQKAPATGNGQLTLDPNYTALYHFDGATGTPAKDTTAY
GNTAQSATGAAIDGVVGRALQFSGQPLLLPASPSLQHNAGSAFTFSAWLRLDQANGEQLILARREGANSLLVGVNQGVPF
VDIDGQRAVATQPLNPGQWQHVALTAEGAKVTLYINGRESAALAQAMPAFNSVMAIGADLHEGPFQPFVGAIDELRLSKV
ARPAPLLLADATSQGAESKLVAYGVDEEQSGFGFGSLGFLLNAVPVDAWVIIAVLVLMMFQSWIIMLRKNRTLSRVTAAN
EDFRVQFAKVGTRLEMFADDTQLAQRLQHSSLWRLYLVAVKEIRTRREQGADTSSVSAATIEAIRCSMDGVRTRENQQLS
SKLSTLSNAIAGGPYIGLLGTVLGIMVVFLGTAMAGDVNINAIAPGMAAALLATAMGLFVAIPALFGYNRLITRNKEVSA
DMRVFVDEFITRLAEMHGEGQSSEAAHQRGHHANQSVPA
>Mature_599_residues
MQRLFLSLLICLGFVLPATAQAWWQDDWHYRKQIAVDTTPQGAAINQALGRTALLVRLHTGNFTFDGVKEDGSDLRFVAA
DDKTVLNHQIESFDALMGMAQIWVDVPNVEGGQRQDIWMYYGNQKAPATGNGQLTLDPNYTALYHFDGATGTPAKDTTAY
GNTAQSATGAAIDGVVGRALQFSGQPLLLPASPSLQHNAGSAFTFSAWLRLDQANGEQLILARREGANSLLVGVNQGVPF
VDIDGQRAVATQPLNPGQWQHVALTAEGAKVTLYINGRESAALAQAMPAFNSVMAIGADLHEGPFQPFVGAIDELRLSKV
ARPAPLLLADATSQGAESKLVAYGVDEEQSGFGFGSLGFLLNAVPVDAWVIIAVLVLMMFQSWIIMLRKNRTLSRVTAAN
EDFRVQFAKVGTRLEMFADDTQLAQRLQHSSLWRLYLVAVKEIRTRREQGADTSSVSAATIEAIRCSMDGVRTRENQQLS
SKLSTLSNAIAGGPYIGLLGTVLGIMVVFLGTAMAGDVNINAIAPGMAAALLATAMGLFVAIPALFGYNRLITRNKEVSA
DMRVFVDEFITRLAEMHGEGQSSEAAHQRGHHANQSVPA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG5306

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=201, Percent_Identity=31.3432835820896, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789381, Length=92, Percent_Identity=38.0434782608696, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 64497; Mature: 64497

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLFLSLLICLGFVLPATAQAWWQDDWHYRKQIAVDTTPQGAAINQALGRTALLVRLHT
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHCCEEEEEEEEC
GNFTFDGVKEDGSDLRFVAADDKTVLNHQIESFDALMGMAQIWVDVPNVEGGQRQDIWMY
CCEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEE
YGNQKAPATGNGQLTLDPNYTALYHFDGATGTPAKDTTAYGNTAQSATGAAIDGVVGRAL
ECCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
QFSGQPLLLPASPSLQHNAGSAFTFSAWLRLDQANGEQLILARREGANSLLVGVNQGVPF
HCCCCEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCE
VDIDGQRAVATQPLNPGQWQHVALTAEGAKVTLYINGRESAALAQAMPAFNSVMAIGADL
EEECCCCEEEECCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
HEGPFQPFVGAIDELRLSKVARPAPLLLADATSQGAESKLVAYGVDEEQSGFGFGSLGFL
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHH
LNAVPVDAWVIIAVLVLMMFQSWIIMLRKNRTLSRVTAANEDFRVQFAKVGTRLEMFADD
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHCCCCEECCCH
TQLAQRLQHSSLWRLYLVAVKEIRTRREQGADTSSVSAATIEAIRCSMDGVRTRENQQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
SKLSTLSNAIAGGPYIGLLGTVLGIMVVFLGTAMAGDVNINAIAPGMAAALLATAMGLFV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
AIPALFGYNRLITRNKEVSADMRVFVDEFITRLAEMHGEGQSSEAAHQRGHHANQSVPA
HHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQRLFLSLLICLGFVLPATAQAWWQDDWHYRKQIAVDTTPQGAAINQALGRTALLVRLHT
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHCCEEEEEEEEC
GNFTFDGVKEDGSDLRFVAADDKTVLNHQIESFDALMGMAQIWVDVPNVEGGQRQDIWMY
CCEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEE
YGNQKAPATGNGQLTLDPNYTALYHFDGATGTPAKDTTAYGNTAQSATGAAIDGVVGRAL
ECCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
QFSGQPLLLPASPSLQHNAGSAFTFSAWLRLDQANGEQLILARREGANSLLVGVNQGVPF
HCCCCEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCE
VDIDGQRAVATQPLNPGQWQHVALTAEGAKVTLYINGRESAALAQAMPAFNSVMAIGADL
EEECCCCEEEECCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
HEGPFQPFVGAIDELRLSKVARPAPLLLADATSQGAESKLVAYGVDEEQSGFGFGSLGFL
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHH
LNAVPVDAWVIIAVLVLMMFQSWIIMLRKNRTLSRVTAANEDFRVQFAKVGTRLEMFADD
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHCCCCEECCCH
TQLAQRLQHSSLWRLYLVAVKEIRTRREQGADTSSVSAATIEAIRCSMDGVRTRENQQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
SKLSTLSNAIAGGPYIGLLGTVLGIMVVFLGTAMAGDVNINAIAPGMAAALLATAMGLFV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
AIPALFGYNRLITRNKEVSADMRVFVDEFITRLAEMHGEGQSSEAAHQRGHHANQSVPA
HHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]