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The map label for this gene is rssA [H]

Identifier: 77457582

GI number: 77457582

Start: 1529974

End: 1531359

Strand: Direct

Name: rssA [H]

Synonym: Pfl01_1355

Alternate gene names: 77457582

Gene position: 1529974-1531359 (Clockwise)

Preceding gene: 77457581

Following gene: 77457585

Centisome position: 23.76

GC content: 64.79

Gene sequence:

>1386_bases
ATGCATAAGCCCAGCAGCTTGCGCTGGCGGTTGCTGTGGAACCTCGCGTTGCTGCTGGTGGTGTTGATGCTCGCCAGCGG
ATTGAGCGCCTACTGGAACGGTCGCGAGGCCGCCGACACCGCCTATGACCGCACGCTGCTGGCCTCGGCGCGGACCATCG
CCGCCGGTCTGTCGCAGCGCGATGGCAGTCTCAGTGCCGACGTGCCGTATGTGGCGCTCGATACGTTTGCTTACGACAGC
GCGGGTCGTATCTATTACCAGGTCAACGACATCAACCAGAAGTTGATTTCCGGCTATGAAAATCTGCCGGGCCCGCCGCC
AGGCACGCCGAGAACCGACAGCTATCCCGCCCTCGCGCGCTTTTACGACGCGAAATATCAGGGGCAGAACGTGCGTGTGG
TGAGTCTGCTCAAGGCGGTCAGCGAGCCGAACATGAACGGCATGGCGGAAATCCGCGTCGCCGAAACCGACGAGGCACGC
GTCAGCATGGCTCGCAGTCTGGCCGCCGACACCTTGCTGCGATTGGGCATGCTGGCGATTGGCGCGTTGTTGCTGGTGTG
GTTTGCGGTGAGTGCGGCGCTGCGGCCGATCGAACGTTTGCGCACGGCAGTGGAAGAGCGCCAGCCCGATGACCTGCGGC
CGTTGCCGTTGGTCGAGGTGCAACACGAGTTGTGGCCGCTGGTGCGGGCGCTCAATCACTTTACCGAACGCCTGCGCGGG
CAATTCGAGCGGCAGGCGCAATTCATCGCCGATGCGGCCCATGAACTGCGCACCCCACTGGCAGCGCTCAAGGCGCGTCT
TGAACTGGGCTTGCGCTCGAACGAGCCGCAGACCTGGCGCGACACACTGGAATCCTCGGCACAAAGCACGGATCGCCTGA
CCCATCTGGCCAACCAGTTGTTGTCGCTGGCGCGGGTGGAAAACGGCGCCCGGGCGATCGCCGAGGGCGGGGCGCAGTTG
CTCGATCTGAGTCAGCTGGCGCGGGAACTGGGCATGGCCATGGCGCCGCTGGCCCATGCTCGCGGCGTTGCCTTGGCGCT
GGAAGCGGACGAGCCGGTGTGGCTGCGCGGCGAGCCGACATTGCTCAACGAGTTGCTGAGCAATCTGGTGGACAACGCAC
TGGCGCACACGCCGCCGGGCGGCAACGTGATTCTGCGGGTCACTGCGCCCGCGGTGCTGGAGGTTGAAGACGATGGGCCG
GGCATTCCGCTGGAAGAGCGGGATCGGGTGTTCGAACGTTTTTACCGGCGCAACCAGCAGGTCGCTGGTTCCGGGCTGGG
GCTGGCGATTGTCGGGGAGATCTGCCGCGCGCATCTGGCGCAGATCAGTCTGCACGATGGTGAACAGGCGGGTTTGAAGG
TACGGGTGAGTTTTGTCGCCGGTTGA

Upstream 100 bases:

>100_bases
GCCATCGAAATCTACGTGCATCGCCTGCGCAAAAAGCTCGACGGCCATTCGGTGGCTATCGTGACCTTCCGCGGTCTGGG
CTATCTGCTGGAAAGCCGCG

Downstream 100 bases:

>100_bases
TCAGTAGAACATCGACCGCGATTCTTCCAGATCGGTGCACAGCGCCTTGTTCTCCGGGTCGATGCCGAGCTTGCGGAATG
CCGGCACGCTGAACGGATCG

Product: periplasmic sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MHKPSSLRWRLLWNLALLLVVLMLASGLSAYWNGREAADTAYDRTLLASARTIAAGLSQRDGSLSADVPYVALDTFAYDS
AGRIYYQVNDINQKLISGYENLPGPPPGTPRTDSYPALARFYDAKYQGQNVRVVSLLKAVSEPNMNGMAEIRVAETDEAR
VSMARSLAADTLLRLGMLAIGALLLVWFAVSAALRPIERLRTAVEERQPDDLRPLPLVEVQHELWPLVRALNHFTERLRG
QFERQAQFIADAAHELRTPLAALKARLELGLRSNEPQTWRDTLESSAQSTDRLTHLANQLLSLARVENGARAIAEGGAQL
LDLSQLARELGMAMAPLAHARGVALALEADEPVWLRGEPTLLNELLSNLVDNALAHTPPGGNVILRVTAPAVLEVEDDGP
GIPLEERDRVFERFYRRNQQVAGSGLGLAIVGEICRAHLAQISLHDGEQAGLKVRVSFVAG

Sequences:

>Translated_461_residues
MHKPSSLRWRLLWNLALLLVVLMLASGLSAYWNGREAADTAYDRTLLASARTIAAGLSQRDGSLSADVPYVALDTFAYDS
AGRIYYQVNDINQKLISGYENLPGPPPGTPRTDSYPALARFYDAKYQGQNVRVVSLLKAVSEPNMNGMAEIRVAETDEAR
VSMARSLAADTLLRLGMLAIGALLLVWFAVSAALRPIERLRTAVEERQPDDLRPLPLVEVQHELWPLVRALNHFTERLRG
QFERQAQFIADAAHELRTPLAALKARLELGLRSNEPQTWRDTLESSAQSTDRLTHLANQLLSLARVENGARAIAEGGAQL
LDLSQLARELGMAMAPLAHARGVALALEADEPVWLRGEPTLLNELLSNLVDNALAHTPPGGNVILRVTAPAVLEVEDDGP
GIPLEERDRVFERFYRRNQQVAGSGLGLAIVGEICRAHLAQISLHDGEQAGLKVRVSFVAG
>Mature_461_residues
MHKPSSLRWRLLWNLALLLVVLMLASGLSAYWNGREAADTAYDRTLLASARTIAAGLSQRDGSLSADVPYVALDTFAYDS
AGRIYYQVNDINQKLISGYENLPGPPPGTPRTDSYPALARFYDAKYQGQNVRVVSLLKAVSEPNMNGMAEIRVAETDEAR
VSMARSLAADTLLRLGMLAIGALLLVWFAVSAALRPIERLRTAVEERQPDDLRPLPLVEVQHELWPLVRALNHFTERLRG
QFERQAQFIADAAHELRTPLAALKARLELGLRSNEPQTWRDTLESSAQSTDRLTHLANQLLSLARVENGARAIAEGGAQL
LDLSQLARELGMAMAPLAHARGVALALEADEPVWLRGEPTLLNELLSNLVDNALAHTPPGGNVILRVTAPAVLEVEDDGP
GIPLEERDRVFERFYRRNQQVAGSGLGLAIVGEICRAHLAQISLHDGEQAGLKVRVSFVAG

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=319, Percent_Identity=33.2288401253918, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786783, Length=282, Percent_Identity=32.2695035460993, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790551, Length=278, Percent_Identity=30.5755395683453, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=33.1818181818182, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=30.1818181818182, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790861, Length=328, Percent_Identity=29.8780487804878, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788279, Length=301, Percent_Identity=24.9169435215947, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787374, Length=481, Percent_Identity=25.3638253638254, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=29.9270072992701, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=28.5067873303167, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=217, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=25.764192139738, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789808, Length=302, Percent_Identity=26.8211920529801, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=247, Percent_Identity=28.7449392712551, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=28.9915966386555, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081816, Length=375, Percent_Identity=25.0666666666667, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=274, Percent_Identity=28.4671532846715, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994928, Length=217, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50491; Mature: 50491

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKPSSLRWRLLWNLALLLVVLMLASGLSAYWNGREAADTAYDRTLLASARTIAAGLSQR
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DGSLSADVPYVALDTFAYDSAGRIYYQVNDINQKLISGYENLPGPPPGTPRTDSYPALAR
CCCCCCCCCEEEEEHHEECCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
FYDAKYQGQNVRVVSLLKAVSEPNMNGMAEIRVAETDEARVSMARSLAADTLLRLGMLAI
HHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GALLLVWFAVSAALRPIERLRTAVEERQPDDLRPLPLVEVQHELWPLVRALNHFTERLRG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QFERQAQFIADAAHELRTPLAALKARLELGLRSNEPQTWRDTLESSAQSTDRLTHLANQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSLARVENGARAIAEGGAQLLDLSQLARELGMAMAPLAHARGVALALEADEPVWLRGEPT
HHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCHH
LLNELLSNLVDNALAHTPPGGNVILRVTAPAVLEVEDDGPGIPLEERDRVFERFYRRNQQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHCCH
VAGSGLGLAIVGEICRAHLAQISLHDGEQAGLKVRVSFVAG
HCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MHKPSSLRWRLLWNLALLLVVLMLASGLSAYWNGREAADTAYDRTLLASARTIAAGLSQR
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DGSLSADVPYVALDTFAYDSAGRIYYQVNDINQKLISGYENLPGPPPGTPRTDSYPALAR
CCCCCCCCCEEEEEHHEECCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
FYDAKYQGQNVRVVSLLKAVSEPNMNGMAEIRVAETDEARVSMARSLAADTLLRLGMLAI
HHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GALLLVWFAVSAALRPIERLRTAVEERQPDDLRPLPLVEVQHELWPLVRALNHFTERLRG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QFERQAQFIADAAHELRTPLAALKARLELGLRSNEPQTWRDTLESSAQSTDRLTHLANQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSLARVENGARAIAEGGAQLLDLSQLARELGMAMAPLAHARGVALALEADEPVWLRGEPT
HHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCHH
LLNELLSNLVDNALAHTPPGGNVILRVTAPAVLEVEDDGPGIPLEERDRVFERFYRRNQQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHCCH
VAGSGLGLAIVGEICRAHLAQISLHDGEQAGLKVRVSFVAG
HCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA