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The map label for this gene is tctD [H]

Identifier: 77457581

GI number: 77457581

Start: 1529310

End: 1529981

Strand: Direct

Name: tctD [H]

Synonym: Pfl01_1354

Alternate gene names: 77457581

Gene position: 1529310-1529981 (Clockwise)

Preceding gene: 77457576

Following gene: 77457582

Centisome position: 23.75

GC content: 63.54

Gene sequence:

>672_bases
ATGCGTGTCCTGCTCGTCGAAGACCATTTGCCGCTGGCCGAAAGCGTTGCCCAGGCGCTCAAGAGCACCGGTCTGACCGT
GGACGTCTTGCACGATGGCGTGGCTGCCGACCTGGCTCTGGGCAGCGAGGAATACGCGGTGGCGATCCTTGATGTCGGCC
TGCCACGCATGGACGGTTTTGAAGTGCTGGCGCGCCTGCGGGCTCGGGGCAAGAATCTGCCGGTGCTGATGCTGACCGCT
CGTAGCGACGTCAAGGATCGGGTCCACGGGCTCAATCTCGGCGCCGACGATTACCTCGCCAAACCGTTCGAACTCACCGA
ACTCGAGGCGCGGGTCAAGGCCCTGTTGCGCCGCAGCGTGCTCGGCGGCGAACGCCAGCAGCGTTGCGGTGTGCTGGCCT
ATGACCTCGACACCCGGCGCTTCACCCTCGGCGATGAATTGTTGACGCTGACTTCTCGCGAACAGGCGGTGCTCGAAGCG
CTGATTGCCCGTCCCGGTCGGGTGATGAGCAAAGAACAGCTGGCTGCGCAGGTGTTCGGTCTCGACGAAGAGGCCAGCCC
CGACGCCATCGAAATCTACGTGCATCGCCTGCGCAAAAAGCTCGACGGCCATTCGGTGGCTATCGTGACCTTCCGCGGTC
TGGGCTATCTGCTGGAAAGCCGCGATGCATAA

Upstream 100 bases:

>100_bases
AGTATTCTTTCGCATGTTTTCGGGCTTCACAGTGGCGGTTGCGGCTGTAAACTCCGCCGCAAAGAATGGCGTCGGCCATC
CCTGAATGAGGTAGAGATCC

Downstream 100 bases:

>100_bases
GCCCAGCAGCTTGCGCTGGCGGTTGCTGTGGAACCTCGCGTTGCTGCTGGTGGTGTTGATGCTCGCCAGCGGATTGAGCG
CCTACTGGAACGGTCGCGAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRVLLVEDHLPLAESVAQALKSTGLTVDVLHDGVAADLALGSEEYAVAILDVGLPRMDGFEVLARLRARGKNLPVLMLTA
RSDVKDRVHGLNLGADDYLAKPFELTELEARVKALLRRSVLGGERQQRCGVLAYDLDTRRFTLGDELLTLTSREQAVLEA
LIARPGRVMSKEQLAAQVFGLDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDA

Sequences:

>Translated_223_residues
MRVLLVEDHLPLAESVAQALKSTGLTVDVLHDGVAADLALGSEEYAVAILDVGLPRMDGFEVLARLRARGKNLPVLMLTA
RSDVKDRVHGLNLGADDYLAKPFELTELEARVKALLRRSVLGGERQQRCGVLAYDLDTRRFTLGDELLTLTSREQAVLEA
LIARPGRVMSKEQLAAQVFGLDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDA
>Mature_223_residues
MRVLLVEDHLPLAESVAQALKSTGLTVDVLHDGVAADLALGSEEYAVAILDVGLPRMDGFEVLARLRARGKNLPVLMLTA
RSDVKDRVHGLNLGADDYLAKPFELTELEARVKALLRRSVLGGERQQRCGVLAYDLDTRRFTLGDELLTLTSREQAVLEA
LIARPGRVMSKEQLAAQVFGLDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDA

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=42.2018348623853, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=38.9908256880734, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=37.6106194690265, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=37.219730941704, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=36.2385321100917, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=34.3612334801762, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=35.1111111111111, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=37.10407239819, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.9307359307359, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=30.8035714285714, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=34.070796460177, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=27.8761061946903, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=33.0434782608696, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=122, Percent_Identity=33.6065573770492, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=123, Percent_Identity=29.2682926829268, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=33.0578512396694, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=24.2424242424242, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24509; Mature: 24509

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDHLPLAESVAQALKSTGLTVDVLHDGVAADLALGSEEYAVAILDVGLPRMDGF
CEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCEEEEEEECCCCCCCHH
EVLARLRARGKNLPVLMLTARSDVKDRVHGLNLGADDYLAKPFELTELEARVKALLRRSV
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHH
LGGERQQRCGVLAYDLDTRRFTLGDELLTLTSREQAVLEALIARPGRVMSKEQLAAQVFG
HCCCHHHHCCEEEEECCCCEEECCCHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHC
LDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDA
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHCCCC
>Mature Secondary Structure
MRVLLVEDHLPLAESVAQALKSTGLTVDVLHDGVAADLALGSEEYAVAILDVGLPRMDGF
CEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCEEEEEEECCCCCCCHH
EVLARLRARGKNLPVLMLTARSDVKDRVHGLNLGADDYLAKPFELTELEARVKALLRRSV
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHH
LGGERQQRCGVLAYDLDTRRFTLGDELLTLTSREQAVLEALIARPGRVMSKEQLAAQVFG
HCCCHHHHCCEEEEECCCCEEECCCHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHC
LDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDA
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]