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The map label for this gene is xerD [H]

Identifier: 77457252

GI number: 77457252

Start: 1188840

End: 1189736

Strand: Direct

Name: xerD [H]

Synonym: Pfl01_1025

Alternate gene names: 77457252

Gene position: 1188840-1189736 (Clockwise)

Preceding gene: 77457250

Following gene: 77457253

Centisome position: 18.46

GC content: 61.65

Gene sequence:

>897_bases
ATGCCTGCCATCGACCACCCACTGATCGACCAGTTTCTCGACGCCCTCTGGCTGGAAAAAGGTCTCTCCGACAACACTCG
CGACGCCTACCGCAGCGATCTCGCGCTGTTCAACGGCTGGTTGCAGGATAAAGGTCTCGAACTGATCAATGCCGGTCGTG
AACTGATCCTTGACCACCTGGCCTGGCGTCTGGAACAGAACTACAAACCCCGCTCCACCGCGCGATTTCTCTCCGGTGTA
CGTGGCTTTTATCGCTACCTGCTGCGGGAAAAACTGATTTCGGTCGATCCGACCTTGCGCGTGGATATGCCGCAACTCGG
TCGGCCATTGCCCAAATCCCTGTCGGAAGCCGACGTCGAAGCGCTGCTGAAGGCGCCAGACCTGAGCGAAGCCATCGGCC
AGCGGGACCGCGCCATGCTCGAAGTCTTGTATGCCTGCGGTCTGCGTGTCACTGAGCTGATCAGCCTGACCCTGGAGCAG
GTCAACCTGCGTCAGGGCGTGCTGCGGGTGATGGGCAAGGGCAGTAAAGAGCGCCTTGTACCGATGGGCGAGGAAGCGAT
TGTCTGGGTCGAGCGCTACCTGCGCGACGGTCGCGGCGAGCTGCTCGGCGGGCGCCCCAGCGATGTGTTGTTTCCCAGCC
AGCGCGGCGAGCAGATGACTCGGCAGACCTTCTGGCACCGTATCAAGCATCAGGCCAAGGTCGCCGGCATCAGTAAATCG
CTGTCGCCGCACACCTTGCGTCACGCGTTTGCCACCCACTTGCTCAACCATGGCGCCGACTTGCGGGTGGTGCAGATGCT
GTTGGGCCACAGCGACCTGTCAACCACGCAGATCTACACTCACGTCGCCCGGGCACGTTTGCAGGATCTGCATGCCAAGC
ATCACCCGCGCGGCTGA

Upstream 100 bases:

>100_bases
CCCTGTTCCTTGAAATAGCGGGCTATGAAAGACTAGCGGCCATTTCAACCGTTCACTCTTTATTTGCGCGCAGTGCCAAG
CCTGCGTGTCTTGAGCGCCC

Downstream 100 bases:

>100_bases
GCGCCGTTTGTCTTGCGACAGGCGCATTCGGCCACGCCAGCCTTATGTGGTAGGCTTTGCCGGTTTGCACGATGGGCGGT
TATGACCCGGTGTTCCGGCA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPAIDHPLIDQFLDALWLEKGLSDNTRDAYRSDLALFNGWLQDKGLELINAGRELILDHLAWRLEQNYKPRSTARFLSGV
RGFYRYLLREKLISVDPTLRVDMPQLGRPLPKSLSEADVEALLKAPDLSEAIGQRDRAMLEVLYACGLRVTELISLTLEQ
VNLRQGVLRVMGKGSKERLVPMGEEAIVWVERYLRDGRGELLGGRPSDVLFPSQRGEQMTRQTFWHRIKHQAKVAGISKS
LSPHTLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVARARLQDLHAKHHPRG

Sequences:

>Translated_298_residues
MPAIDHPLIDQFLDALWLEKGLSDNTRDAYRSDLALFNGWLQDKGLELINAGRELILDHLAWRLEQNYKPRSTARFLSGV
RGFYRYLLREKLISVDPTLRVDMPQLGRPLPKSLSEADVEALLKAPDLSEAIGQRDRAMLEVLYACGLRVTELISLTLEQ
VNLRQGVLRVMGKGSKERLVPMGEEAIVWVERYLRDGRGELLGGRPSDVLFPSQRGEQMTRQTFWHRIKHQAKVAGISKS
LSPHTLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVARARLQDLHAKHHPRG
>Mature_297_residues
PAIDHPLIDQFLDALWLEKGLSDNTRDAYRSDLALFNGWLQDKGLELINAGRELILDHLAWRLEQNYKPRSTARFLSGVR
GFYRYLLREKLISVDPTLRVDMPQLGRPLPKSLSEADVEALLKAPDLSEAIGQRDRAMLEVLYACGLRVTELISLTLEQV
NLRQGVLRVMGKGSKERLVPMGEEAIVWVERYLRDGRGELLGGRPSDVLFPSQRGEQMTRQTFWHRIKHQAKVAGISKSL
SPHTLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVARARLQDLHAKHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=63.2302405498282, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=35.8108108108108, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1790768, Length=180, Percent_Identity=30, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=26.7441860465116, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33876; Mature: 33744

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAIDHPLIDQFLDALWLEKGLSDNTRDAYRSDLALFNGWLQDKGLELINAGRELILDHL
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AWRLEQNYKPRSTARFLSGVRGFYRYLLREKLISVDPTLRVDMPQLGRPLPKSLSEADVE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHCCCCHHHHHHHHHH
ALLKAPDLSEAIGQRDRAMLEVLYACGLRVTELISLTLEQVNLRQGVLRVMGKGSKERLV
HHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
PMGEEAIVWVERYLRDGRGELLGGRPSDVLFPSQRGEQMTRQTFWHRIKHQAKVAGISKS
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSPHTLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVARARLQDLHAKHHPRG
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PAIDHPLIDQFLDALWLEKGLSDNTRDAYRSDLALFNGWLQDKGLELINAGRELILDHL
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AWRLEQNYKPRSTARFLSGVRGFYRYLLREKLISVDPTLRVDMPQLGRPLPKSLSEADVE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHCCCCHHHHHHHHHH
ALLKAPDLSEAIGQRDRAMLEVLYACGLRVTELISLTLEQVNLRQGVLRVMGKGSKERLV
HHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
PMGEEAIVWVERYLRDGRGELLGGRPSDVLFPSQRGEQMTRQTFWHRIKHQAKVAGISKS
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSPHTLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVARARLQDLHAKHHPRG
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]