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The map label for this gene is ywbI [H]

Identifier: 77457125

GI number: 77457125

Start: 1041741

End: 1042628

Strand: Reverse

Name: ywbI [H]

Synonym: Pfl01_0898

Alternate gene names: 77457125

Gene position: 1042628-1041741 (Counterclockwise)

Preceding gene: 77457131

Following gene: 77457123

Centisome position: 16.19

GC content: 61.94

Gene sequence:

>888_bases
ATGGAATTCAAACAACTCAGAAGTTTCGTCGAAGTCATGCATCAGGGCGGTTTCACTCAAGCTGCGAAGACCCTGCACAT
CAGTCAGTCCGCCGTGAGCAAGCAGATCGCCCAGCTCGAACAGAGTCTCGGCACCCCGCTTCTCGAACGGCTCGGCTCGC
AGATACGCCTGACCGCCGCCGGCAGTGTGGTGTTGCATCGGGCCGAAGGCATGCTGCGCTTGCGCAATGAATTGCTCAGC
GAACTGGATGACCTCAGCCAACTGGCACGGGGCGAGTTACGTCTCGGGCTGCCCTTGCTGGGCAGCGATGCATTGTTTGC
CGGGCTGTTTGCCGAATACCGACGGCGCTATCCGAACATCAGCGTGCAGTTGCTTGAAGGTGGCAGCCGCAATATCGAAC
AGGCGGTGCTCAGCGGGGAGCTGGAGTTGGGTGGCAGTCTGCTGCCGAAGGATCCGCAATTCGACTTTCAGCCGTTCTGT
GATGAACCGCTGGATGCGCTGCTTCCGGTGGATCACCCGCTGGCGGCAAAAGGCGAAATCGGTCTGGAGGAACTGGCCGA
TACGCCGTTCCTTTTGTATCAGCGCAGTTTCGTGCTCAACGATCGTTTGCTTCAGGCGTGCCAGCAAATGGGCTTCACGC
CGAAAGAAGGCGGGCGCAGTGGTCAGGCGGATTTTCTCGCGGCGCTGGTCGCCGCCGGGCAGGGCGTGGTGTTGCTGCCC
AGCGTGGTGGCGCGCGGTCTGGTGCGGCCAGGCGTGGTGCGCCTGACCTTGAACGCGCCGGACTACCTGCGCTGGGACAT
CGCTTTCATCTGGCGCCGGGGCGCCTATCTGTCGAAGGCTGCGCAGGCCTGGCTGGCGCTGCTGCGTGAACGTGGAATCA
GCCCTTGA

Upstream 100 bases:

>100_bases
TTCATCGATGGGCTCCTTTCAGGTGGCTATCTTACGAACCCGGCTACCATCTCCGAAGCGAATTGTTAGACTCAAAGCCA
TTCCAATCTGGAATCAGGCC

Downstream 100 bases:

>100_bases
GCGTGGCGATCAACTGTTGCAGCCAAGGCTCGGCGTCGGTTTCCGGGGTAACGCTTTCGCTGGCGTCGATGCGCAGCATG
TCCTGCACCTCGCGTACGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MEFKQLRSFVEVMHQGGFTQAAKTLHISQSAVSKQIAQLEQSLGTPLLERLGSQIRLTAAGSVVLHRAEGMLRLRNELLS
ELDDLSQLARGELRLGLPLLGSDALFAGLFAEYRRRYPNISVQLLEGGSRNIEQAVLSGELELGGSLLPKDPQFDFQPFC
DEPLDALLPVDHPLAAKGEIGLEELADTPFLLYQRSFVLNDRLLQACQQMGFTPKEGGRSGQADFLAALVAAGQGVVLLP
SVVARGLVRPGVVRLTLNAPDYLRWDIAFIWRRGAYLSKAAQAWLALLRERGISP

Sequences:

>Translated_295_residues
MEFKQLRSFVEVMHQGGFTQAAKTLHISQSAVSKQIAQLEQSLGTPLLERLGSQIRLTAAGSVVLHRAEGMLRLRNELLS
ELDDLSQLARGELRLGLPLLGSDALFAGLFAEYRRRYPNISVQLLEGGSRNIEQAVLSGELELGGSLLPKDPQFDFQPFC
DEPLDALLPVDHPLAAKGEIGLEELADTPFLLYQRSFVLNDRLLQACQQMGFTPKEGGRSGQADFLAALVAAGQGVVLLP
SVVARGLVRPGVVRLTLNAPDYLRWDIAFIWRRGAYLSKAAQAWLALLRERGISP
>Mature_295_residues
MEFKQLRSFVEVMHQGGFTQAAKTLHISQSAVSKQIAQLEQSLGTPLLERLGSQIRLTAAGSVVLHRAEGMLRLRNELLS
ELDDLSQLARGELRLGLPLLGSDALFAGLFAEYRRRYPNISVQLLEGGSRNIEQAVLSGELELGGSLLPKDPQFDFQPFC
DEPLDALLPVDHPLAAKGEIGLEELADTPFLLYQRSFVLNDRLLQACQQMGFTPKEGGRSGQADFLAALVAAGQGVVLLP
SVVARGLVRPGVVRLTLNAPDYLRWDIAFIWRRGAYLSKAAQAWLALLRERGISP

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=288, Percent_Identity=30.2083333333333, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787879, Length=254, Percent_Identity=33.0708661417323, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=28.5223367697594, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788887, Length=192, Percent_Identity=34.375, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=27.891156462585, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787530, Length=289, Percent_Identity=26.9896193771626, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790262, Length=257, Percent_Identity=28.7937743190661, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788481, Length=196, Percent_Identity=30.1020408163265, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789506, Length=295, Percent_Identity=24.0677966101695, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=255, Percent_Identity=26.2745098039216, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788296, Length=259, Percent_Identity=25.0965250965251, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788748, Length=293, Percent_Identity=26.6211604095563, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=25.6916996047431, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=264, Percent_Identity=25.7575757575758, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790208, Length=246, Percent_Identity=23.5772357723577, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789639, Length=125, Percent_Identity=32, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=298, Percent_Identity=27.5167785234899, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=274, Percent_Identity=22.992700729927, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786401, Length=144, Percent_Identity=29.1666666666667, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32351; Mature: 32351

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKQLRSFVEVMHQGGFTQAAKTLHISQSAVSKQIAQLEQSLGTPLLERLGSQIRLTAA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEH
GSVVLHRAEGMLRLRNELLSELDDLSQLARGELRLGLPLLGSDALFAGLFAEYRRRYPNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHCCCC
SVQLLEGGSRNIEQAVLSGELELGGSLLPKDPQFDFQPFCDEPLDALLPVDHPLAAKGEI
EEEEECCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCC
GLEELADTPFLLYQRSFVLNDRLLQACQQMGFTPKEGGRSGQADFLAALVAAGQGVVLLP
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHH
SVVARGLVRPGVVRLTLNAPDYLRWDIAFIWRRGAYLSKAAQAWLALLRERGISP
HHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEFKQLRSFVEVMHQGGFTQAAKTLHISQSAVSKQIAQLEQSLGTPLLERLGSQIRLTAA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEH
GSVVLHRAEGMLRLRNELLSELDDLSQLARGELRLGLPLLGSDALFAGLFAEYRRRYPNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHCCCC
SVQLLEGGSRNIEQAVLSGELELGGSLLPKDPQFDFQPFCDEPLDALLPVDHPLAAKGEI
EEEEECCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCC
GLEELADTPFLLYQRSFVLNDRLLQACQQMGFTPKEGGRSGQADFLAALVAAGQGVVLLP
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHH
SVVARGLVRPGVVRLTLNAPDYLRWDIAFIWRRGAYLSKAAQAWLALLRERGISP
HHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]