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The map label for this gene is hlyB [H]

Identifier: 77456956

GI number: 77456956

Start: 855264

End: 857183

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_0728

Alternate gene names: 77456956

Gene position: 857183-855264 (Counterclockwise)

Preceding gene: 77456959

Following gene: 77456955

Centisome position: 13.31

GC content: 63.59

Gene sequence:

>1920_bases
ATGAATAGCTGGTTCGGCAACATCAGCGTGAACCTGAAACTGGGGCTCGGATTCGGCCTCGTCCTGGCCCTGACCTGCAT
CCTGGCACTCACTGGCTGGACCAGCCTGGGCGGCCTGATTGACCGCAGCAACTGGATGAGCGACATCACCCAGCTCAACG
CTGGCCTGACCAAACTGCGCGTGGTGCGCCTGCAATACATGCTGACCAACGGCGACGAAACCGCCGCGCAGAACGTGCAG
ACCACCCTCGACGGGTTCGCCGCCCAACAGCAGAAGCTGATAAGCAGCTTCAAGAGCCCGGAAAACGTCAAACTGCTCAA
GGAGCAGGCGGCGACCATCGCCGAATACCAGACGTCCCTGAACAAAATGCGTAACGCCTACCGCACCGGCAACACGGCGC
GCGACTCGATGGCCACCAGTGCCGCGACGGCTTACGGCCTGATCGAAGCGCTGAGCAACCGCGTTCAGCAAATGCCGCTG
AGCGATGAACGTTTCGAGCAGTTCCAGGCCGTCACCGCCGCCAAGGAAGCGTTCATCCTGGCGCGCTACGAAGTGCGTGG
CTACACCGCCACCGCCAACGCCGAGACCGAGCAGAAAGCCGTCGGCCAACTGGACGTGGCCATCGCCAGCCTCAAGCCAC
TGAACACGCATTTCGCCAGCACCCAACAGGACGCCCTGCGTCAGCTGGAAACCGCACTGACCAACTACCGCAGCGCCTTG
CAGGCGTTCAAGAACGCCAACACCGATGCGGTGCAGGCGCGCAAGGAAATGACCGATCAGGGCGCGACCATCGTGACCCT
GAGCGAGCAGTTGTATCAGATCCAGCTCGATCGCCGTGATGCAGAAAGCGCCCAGGCCCGCACCCTGCAACTGATCAGCA
CCCTGCTGGCGTTGCTGGTCGGCATCATCGCTGCCTTCATCATCACCCGTCAGATCACCCGTCCGCTGCAGGAAACCATG
GCTGTGGTCGACCGCATCGCCAGCGGCGACCTGAGCCACAACGTGATCGTCACCCGCCGCGACGAACTCGGCGTGCTGCA
ACAAGGCATCGCGCGCATGGGCGTGACCCTGCGCGACCTGATCAGCGGCATCCGCGACGGCGTGACCCAGATCGCCAGCG
CCGCCGAAGAACTGTCGGCCGTGACCGAACAGACCAGCGCCGGCGTGAACAGCCAGAAGGTCGAGACCGATCAGGTCGCC
ACCGCGATGCACGAGATGACTGCCACTGTGCAGGAAGTCGCGCGCAATGCCGAAGAAGCCTCGCAAGCCGCAGCCGCCGC
TGACGGCGAAGCCCGCGAAGGCGATAAGGTGGTGAACGAAGCCATCGCCCAGATCGAGCGTCTGGCCAGCGAAGTGGTGC
GCTCCACCGAAGCCATGAGCGTGCTGCAACAGGAAAGCGACAAGATCGGCAGCGTCATGGACGTGATCAAGGCTGTGGCC
GAACAGACCAACCTGCTGGCCCTCAACGCCGCCATCGAAGCCGCCCGTGCCGGTGAAGCCGGTCGTGGTTTTGCCGTGGT
CGCCGACGAAGTCCGTGGCCTGGCCCAGCGCACGCAGAAATCCACCGAGGAAATCGAAGGCCTGGTGGCCGGTCTGCAGA
ACGGCACGCAGCAAGTGGCCGCCGTGATGAACAACAGCCGCGCCCTGACCGACAGCAGCGTCGCCCTGACCCGCAAGGCC
GGCGACTCCCTGGAAAACATCACCCGCACGGTGTCGAACATCCAGTCGATGAACCAGCAGATCGCCGCAGCCGCCGAACA
GCAAAGCGCCGTGGCCGAAGAAATCAGCCGCAGCATCATCAACGTCCGCGACGTGTCGGAACAGACCGCAGCGGCGAGTG
ATGAGACGGCCAAGTCCAGCGTTGAACTGGCGCGGTTGGGTGGGCAGTTGCAGCAGATGGTGAGCCATTTCCGCGTGTAA

Upstream 100 bases:

>100_bases
CCGATACAGTCCTGCTTACACCCTTGCTGGCGCAAAAAAACAACAATCTTCCAGCCTGACCGACGATCAAGACGCACAAC
GTTTTTCTGGAGGATTTTTG

Downstream 100 bases:

>100_bases
ACCCTGCACACGAAAACCGAAGTACAAAGAAGGGCAGCTGAAAAGCTGCCCTTCTTTTTTGCCCGGAAATTGCCAACTTC
AGGAAGTGGATGACGCGTTC

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MNSWFGNISVNLKLGLGFGLVLALTCILALTGWTSLGGLIDRSNWMSDITQLNAGLTKLRVVRLQYMLTNGDETAAQNVQ
TTLDGFAAQQQKLISSFKSPENVKLLKEQAATIAEYQTSLNKMRNAYRTGNTARDSMATSAATAYGLIEALSNRVQQMPL
SDERFEQFQAVTAAKEAFILARYEVRGYTATANAETEQKAVGQLDVAIASLKPLNTHFASTQQDALRQLETALTNYRSAL
QAFKNANTDAVQARKEMTDQGATIVTLSEQLYQIQLDRRDAESAQARTLQLISTLLALLVGIIAAFIITRQITRPLQETM
AVVDRIASGDLSHNVIVTRRDELGVLQQGIARMGVTLRDLISGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVA
TAMHEMTATVQEVARNAEEASQAAAAADGEAREGDKVVNEAIAQIERLASEVVRSTEAMSVLQQESDKIGSVMDVIKAVA
EQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEGLVAGLQNGTQQVAAVMNNSRALTDSSVALTRKA
GDSLENITRTVSNIQSMNQQIAAAAEQQSAVAEEISRSIINVRDVSEQTAAASDETAKSSVELARLGGQLQQMVSHFRV

Sequences:

>Translated_639_residues
MNSWFGNISVNLKLGLGFGLVLALTCILALTGWTSLGGLIDRSNWMSDITQLNAGLTKLRVVRLQYMLTNGDETAAQNVQ
TTLDGFAAQQQKLISSFKSPENVKLLKEQAATIAEYQTSLNKMRNAYRTGNTARDSMATSAATAYGLIEALSNRVQQMPL
SDERFEQFQAVTAAKEAFILARYEVRGYTATANAETEQKAVGQLDVAIASLKPLNTHFASTQQDALRQLETALTNYRSAL
QAFKNANTDAVQARKEMTDQGATIVTLSEQLYQIQLDRRDAESAQARTLQLISTLLALLVGIIAAFIITRQITRPLQETM
AVVDRIASGDLSHNVIVTRRDELGVLQQGIARMGVTLRDLISGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVA
TAMHEMTATVQEVARNAEEASQAAAAADGEAREGDKVVNEAIAQIERLASEVVRSTEAMSVLQQESDKIGSVMDVIKAVA
EQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEGLVAGLQNGTQQVAAVMNNSRALTDSSVALTRKA
GDSLENITRTVSNIQSMNQQIAAAAEQQSAVAEEISRSIINVRDVSEQTAAASDETAKSSVELARLGGQLQQMVSHFRV
>Mature_639_residues
MNSWFGNISVNLKLGLGFGLVLALTCILALTGWTSLGGLIDRSNWMSDITQLNAGLTKLRVVRLQYMLTNGDETAAQNVQ
TTLDGFAAQQQKLISSFKSPENVKLLKEQAATIAEYQTSLNKMRNAYRTGNTARDSMATSAATAYGLIEALSNRVQQMPL
SDERFEQFQAVTAAKEAFILARYEVRGYTATANAETEQKAVGQLDVAIASLKPLNTHFASTQQDALRQLETALTNYRSAL
QAFKNANTDAVQARKEMTDQGATIVTLSEQLYQIQLDRRDAESAQARTLQLISTLLALLVGIIAAFIITRQITRPLQETM
AVVDRIASGDLSHNVIVTRRDELGVLQQGIARMGVTLRDLISGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVA
TAMHEMTATVQEVARNAEEASQAAAAADGEAREGDKVVNEAIAQIERLASEVVRSTEAMSVLQQESDKIGSVMDVIKAVA
EQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEGLVAGLQNGTQQVAAVMNNSRALTDSSVALTRKA
GDSLENITRTVSNIQSMNQQIAAAAEQQSAVAEEISRSIINVRDVSEQTAAASDETAKSSVELARLGGQLQQMVSHFRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=345, Percent_Identity=34.4927536231884, Blast_Score=163, Evalue=4e-41,
Organism=Escherichia coli, GI1788195, Length=334, Percent_Identity=32.3353293413174, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1788194, Length=381, Percent_Identity=31.496062992126, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI2367378, Length=373, Percent_Identity=30.2949061662198, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1789453, Length=356, Percent_Identity=28.0898876404494, Blast_Score=126, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68652; Mature: 68652

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSWFGNISVNLKLGLGFGLVLALTCILALTGWTSLGGLIDRSNWMSDITQLNAGLTKLR
CCCCEECEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVRLQYMLTNGDETAAQNVQTTLDGFAAQQQKLISSFKSPENVKLLKEQAATIAEYQTSL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
NKMRNAYRTGNTARDSMATSAATAYGLIEALSNRVQQMPLSDERFEQFQAVTAAKEAFIL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ARYEVRGYTATANAETEQKAVGQLDVAIASLKPLNTHFASTQQDALRQLETALTNYRSAL
EEEEECCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
QAFKNANTDAVQARKEMTDQGATIVTLSEQLYQIQLDRRDAESAQARTLQLISTLLALLV
HHHHCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GIIAAFIITRQITRPLQETMAVVDRIASGDLSHNVIVTRRDELGVLQQGIARMGVTLRDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHCCHHHHH
ISGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVATAMHEMTATVQEVARNAEEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQAAAAADGEAREGDKVVNEAIAQIERLASEVVRSTEAMSVLQQESDKIGSVMDVIKAVA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEGLVAGLQNGTQQVA
HHCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVMNNSRALTDSSVALTRKAGDSLENITRTVSNIQSMNQQIAAAAEQQSAVAEEISRSII
HHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVRDVSEQTAAASDETAKSSVELARLGGQLQQMVSHFRV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSWFGNISVNLKLGLGFGLVLALTCILALTGWTSLGGLIDRSNWMSDITQLNAGLTKLR
CCCCEECEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVRLQYMLTNGDETAAQNVQTTLDGFAAQQQKLISSFKSPENVKLLKEQAATIAEYQTSL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
NKMRNAYRTGNTARDSMATSAATAYGLIEALSNRVQQMPLSDERFEQFQAVTAAKEAFIL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ARYEVRGYTATANAETEQKAVGQLDVAIASLKPLNTHFASTQQDALRQLETALTNYRSAL
EEEEECCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
QAFKNANTDAVQARKEMTDQGATIVTLSEQLYQIQLDRRDAESAQARTLQLISTLLALLV
HHHHCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GIIAAFIITRQITRPLQETMAVVDRIASGDLSHNVIVTRRDELGVLQQGIARMGVTLRDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHCCHHHHH
ISGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVATAMHEMTATVQEVARNAEEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQAAAAADGEAREGDKVVNEAIAQIERLASEVVRSTEAMSVLQQESDKIGSVMDVIKAVA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEGLVAGLQNGTQQVA
HHCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVMNNSRALTDSSVALTRKAGDSLENITRTVSNIQSMNQQIAAAAEQQSAVAEEISRSII
HHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVRDVSEQTAAASDETAKSSVELARLGGQLQQMVSHFRV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]