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The map label for this gene is add [H]

Identifier: 77456899

GI number: 77456899

Start: 785257

End: 786210

Strand: Reverse

Name: add [H]

Synonym: Pfl01_0671

Alternate gene names: 77456899

Gene position: 786210-785257 (Counterclockwise)

Preceding gene: 77456900

Following gene: 77456895

Centisome position: 12.21

GC content: 60.48

Gene sequence:

>954_bases
ATGTACGACTGGCTCAACGCCCTGCCCAAGGCCGAACTGCACCTGCACCTCGAAGGCTCGCTGGAGCCCGAGCTGCTGTT
CGCCCTGGCCGAACGCAACAAGATCGCCCTGCCGTGGAGCGACGTCGAAACCCTGCGCAAGGCTTACGCCTTCAACAACC
TGCAGGAATTCCTCGACCTGTATTACCAGGGCGCCGACGTGCTGCGCACCTCCCAGGATTTCTACGACCTGACCTGGGCC
TATCTGCTGCGCTGCAAAGAACAGAACGTGATTCACACCGAGCCGTTCTTCGATCCGCAGACCCACACCGACCGTGGCAT
CCCGTTTGAAGTGGTGCTCAACGGCATCGCCGCCGCGCTGAAGGATGGCGAGCAGCAACTGGGCATCACCAGCGGCCTGA
TCCTGAGTTTCCTGCGTCACCTGAGCGAAGACGAAGCACAGAAAACCCTCGACCAGGCGCTGCCGTTCCGTGATGCGTTT
GTTGCGGTAGGTCTGGACAGTTCCGAAATGGGCCACCCGCCGAGCAAGTTCCAGCGCGTGTTCGACCGTGCCCGTCATGA
AGGTTTCCTGACCGTGGCTCACGCTGGCGAAGAAGGCCCGCCGGAGTACATCTGGGAAGCCATCGACCTGCTGAAAATCC
AGCGCATCGACCATGGCGTACGCGCCATCGAAGATGAGCGTCTGATGCAGCGGATCATCGACGAGCAGATCCCGCTGACC
GTGTGCCCGCTGTCGAATACCAAGCTCTGCGTGTTCGATCACATGTCCCAGCACAATATCCTCGACATGCTCGAGCGTGG
CGTGAAGGTCACGGTGAACTCCGATGACCCGGCGTACTTCGGCGGTTATGTCACCGAGAACTTCCATGCGCTGCACGAAC
ATCTGGGCATGACCCAGGATCAGGCCAAACGCCTGGCGCAGAACAGCCTGGATGCGCGGTTGGTGAAACCGTAA

Upstream 100 bases:

>100_bases
GGAGCAGGAAGCGGTGTGATGGATCGGTTGGTCAGGTTTTGCCAATTGTTTCGGCGGGCATCTGTAGAATGCTCGCCATT
GCACCTGATGAGAAAAGAAT

Downstream 100 bases:

>100_bases
CAGCACAAGGCCGTTCGAACACACCCGTGTTCGAACGGCTTTTCAGTTCTCAGCGCACAACCGCTTCAGTCAACTCTTCC
AGCGTCTTGCCCCGGGTCTC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MYDWLNALPKAELHLHLEGSLEPELLFALAERNKIALPWSDVETLRKAYAFNNLQEFLDLYYQGADVLRTSQDFYDLTWA
YLLRCKEQNVIHTEPFFDPQTHTDRGIPFEVVLNGIAAALKDGEQQLGITSGLILSFLRHLSEDEAQKTLDQALPFRDAF
VAVGLDSSEMGHPPSKFQRVFDRARHEGFLTVAHAGEEGPPEYIWEAIDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
VCPLSNTKLCVFDHMSQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHEHLGMTQDQAKRLAQNSLDARLVKP

Sequences:

>Translated_317_residues
MYDWLNALPKAELHLHLEGSLEPELLFALAERNKIALPWSDVETLRKAYAFNNLQEFLDLYYQGADVLRTSQDFYDLTWA
YLLRCKEQNVIHTEPFFDPQTHTDRGIPFEVVLNGIAAALKDGEQQLGITSGLILSFLRHLSEDEAQKTLDQALPFRDAF
VAVGLDSSEMGHPPSKFQRVFDRARHEGFLTVAHAGEEGPPEYIWEAIDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
VCPLSNTKLCVFDHMSQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHEHLGMTQDQAKRLAQNSLDARLVKP
>Mature_317_residues
MYDWLNALPKAELHLHLEGSLEPELLFALAERNKIALPWSDVETLRKAYAFNNLQEFLDLYYQGADVLRTSQDFYDLTWA
YLLRCKEQNVIHTEPFFDPQTHTDRGIPFEVVLNGIAAALKDGEQQLGITSGLILSFLRHLSEDEAQKTLDQALPFRDAF
VAVGLDSSEMGHPPSKFQRVFDRARHEGFLTVAHAGEEGPPEYIWEAIDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
VCPLSNTKLCVFDHMSQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHEHLGMTQDQAKRLAQNSLDARLVKP

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=323, Percent_Identity=24.7678018575851, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1787910, Length=311, Percent_Identity=28.2958199356913, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32565969, Length=319, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538512, Length=319, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324188, Length=324, Percent_Identity=44.7530864197531, Blast_Score=263, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24645260, Length=316, Percent_Identity=26.2658227848101, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36177; Mature: 36177

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDWLNALPKAELHLHLEGSLEPELLFALAERNKIALPWSDVETLRKAYAFNNLQEFLDL
CCCHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHH
YYQGADVLRTSQDFYDLTWAYLLRCKEQNVIHTEPFFDPQTHTDRGIPFEVVLNGIAAAL
HHCCHHHHHCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
KDGEQQLGITSGLILSFLRHLSEDEAQKTLDQALPFRDAFVAVGLDSSEMGHPPSKFQRV
HCCHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCHHHHHHH
FDRARHEGFLTVAHAGEEGPPEYIWEAIDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VCPLSNTKLCVFDHMSQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHEHLGMTQD
EECCCCCEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHH
QAKRLAQNSLDARLVKP
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYDWLNALPKAELHLHLEGSLEPELLFALAERNKIALPWSDVETLRKAYAFNNLQEFLDL
CCCHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHH
YYQGADVLRTSQDFYDLTWAYLLRCKEQNVIHTEPFFDPQTHTDRGIPFEVVLNGIAAAL
HHCCHHHHHCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
KDGEQQLGITSGLILSFLRHLSEDEAQKTLDQALPFRDAFVAVGLDSSEMGHPPSKFQRV
HCCHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCHHHHHHH
FDRARHEGFLTVAHAGEEGPPEYIWEAIDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VCPLSNTKLCVFDHMSQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHEHLGMTQD
EECCCCCEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHH
QAKRLAQNSLDARLVKP
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA