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The map label for this gene is mcpA [H]

Identifier: 77456885

GI number: 77456885

Start: 770486

End: 772432

Strand: Reverse

Name: mcpA [H]

Synonym: Pfl01_0657

Alternate gene names: 77456885

Gene position: 772432-770486 (Counterclockwise)

Preceding gene: 77456888

Following gene: 77456883

Centisome position: 12.0

GC content: 62.97

Gene sequence:

>1947_bases
ATGAACATCAAACAGAAGTTGACCTGGGCGTTTGCAATCATCGCCTGCTTGCCCGTGGTGCTGGTCGCCACGCTGGTGGT
ACTGAACCTGCGCAGCGATGCCCGGGACGATTTTGTCGACAGTAGTGGGCGCGAGATCCGTCAGGTCAGCAATGCCATGC
AGCTGTTTTTCGACGGCATCAGCCAGAACGTCGATTACCTGGCGGCGCAACCATTGGTCAAAAACGCCGACGGCAGCGTG
CGCAGCCGCATGAGCGCCAACGCTTCCGACACCTCGGATGGCGAGATCGACAAACAACTGTTTGCACTGTTCGAGGGGCT
GGCCAAATCCCACCCGGCCTACTCCTACGTGTCCTATGGATTGAACAGCGGCGGCTATGCCTTCTGGCCGGGCGATCCGA
AGATGGCCAACTACGACCCGCGCACCCGCCCCTGGTACAAGACCGCCATGGCCAACCCGGGCAAGACCCTGCGCACCGAA
GCCTACTACTGGGCCGGCGATGACGCGGTACTGGTCAGCACCGTGCGCGCGGTCGCCAACCAGTTGGGTGCCCAGGGTGG
CGTGGTCAACATTGACGTGTCGCTCAAGCAGCTGACCGAGATCGTCAAACAGATCAAGCTCGGCGAAAGCGGTTATCTGA
TGCTGATGGAAAACACCGGCACGGTGCTGGTCGACCCGAAGCAACCGGAGCACAACTTCAAACGACTCGACAGCCTCGGC
GACGGCTACGCGCAACTGGCCAAGGCCGGTAAAGGCCTGGTTGACATCGAGCTCAACGGCGAGCGCTACATGGCCAATGT
CTGGCCCTCTGAGCAACTGGGCTGGACCTTCATCGGCCTGATCAAACAGAACGACGTGATGAGCTCGGCCACTAAACTCA
CCTGGCTGATCGCAATCATCGCTGCCGTGCTGGCGGTGTTCTTCGCGGTGGTCGGCGCCAGTTTCGCCAGCCTGATCGTG
CGGCCGATCCGCAGCGTGGCCAGCGGTCTGGAAGGCATCGCCCAGGGCGAAGGCGACCTGACCAAGAACCTCGACATCCG
TGGCAGCGACGAAACCGCGCAACTGGCCAACTGGTTCAACCAGTTCCTTACCGCGATCCGCAGTCTGATCCAGCACATCG
GCGGCGCGGCCGGGAAAATCCTCGCCACTTCGCAGAGCTCGACCCGGGTCTCCGGCGACATGGCCGAAGCGGCCGGGCGC
CAGCGCGAAGCGGTGGACATGGTCTCGACCGCGTTCCACGAAATGGTCGCCACCGCCAACGAAGTCGCCCGCTCGTGCAG
CCAGGCGGCGGAGTCGGCCGACAGCGGCCAGCGCCAGGCCCGCGAAGGTCAGCAGCAGATCGATGCGGCGGTGCACAGCG
TCGATCAACTGAGCCAGGAGCTGGAGCAATCGGCGCAGTCGATGCAGCAACTCGAGCGCGACAGCAACGACATCCAGTCG
ATCCTCGGCACCATCCGCTCCATCGCCGAACAGACCAACCTGCTGGCGCTCAACGCGGCCATCGAAGCAGCGCGGGCCGG
TGAGCAGGGGCGTGGTTTTGCGGTAGTGGCCGACGAGGTTCGCGCACTGGCCAAACGCACGGCGGATTCGACGGCGGAAA
TCGACGGGCTGCTGGGCAACCTGGCCAAGCGCACCAGCGCGGTGACCCAGCAAATGCGCGCCAGCCTCGATGTGTCGCAG
CAATCGGTGGCACGCATCGGCGAAGCGCGGGAGAGCTTTGGTCAGATTCGTGAGTCGGTGGATGTGATTCGCGATATGAA
CACGCAGATTGCTACGGCGGCGGAAGAGCAGCATCAGGTGGCTGAGGACATCAATCGGCACATCAGCCAGATTCATGGTG
ATGCGCAGTTGGTGGCGGAACTGGCGAATTCGGCGCGGCTGGATTCGCAGAGTCTGGCGGGGTTGTCGAATGAGCTGGAT
GGGTTGGTGCGGCGGTTCCGGACTTGA

Upstream 100 bases:

>100_bases
ATGTCGCACCCAAGGAAACGGGTGAGAAATAGGTTTTTCGGCTGCCAATAACCGCGAGTCATCTGCACTGCGTGGGCCTA
CAAGAAAATCTGGAGCGCGG

Downstream 100 bases:

>100_bases
GATTGGGGGGCAGCTTGAAAAGCGCCCTCACCCCAGCCCTCTCCCGGAGGGAGAGGGAGCCGACCGAGTTGTCTTGCGTC
ATACATCGACCTGAAAAAAA

Product: Cache sensor-containing chemotaxis sensory transducer

Products: NA

Alternate protein names: H1 [H]

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MNIKQKLTWAFAIIACLPVVLVATLVVLNLRSDARDDFVDSSGREIRQVSNAMQLFFDGISQNVDYLAAQPLVKNADGSV
RSRMSANASDTSDGEIDKQLFALFEGLAKSHPAYSYVSYGLNSGGYAFWPGDPKMANYDPRTRPWYKTAMANPGKTLRTE
AYYWAGDDAVLVSTVRAVANQLGAQGGVVNIDVSLKQLTEIVKQIKLGESGYLMLMENTGTVLVDPKQPEHNFKRLDSLG
DGYAQLAKAGKGLVDIELNGERYMANVWPSEQLGWTFIGLIKQNDVMSSATKLTWLIAIIAAVLAVFFAVVGASFASLIV
RPIRSVASGLEGIAQGEGDLTKNLDIRGSDETAQLANWFNQFLTAIRSLIQHIGGAAGKILATSQSSTRVSGDMAEAAGR
QREAVDMVSTAFHEMVATANEVARSCSQAAESADSGQRQAREGQQQIDAAVHSVDQLSQELEQSAQSMQQLERDSNDIQS
ILGTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTADSTAEIDGLLGNLAKRTSAVTQQMRASLDVSQ
QSVARIGEARESFGQIRESVDVIRDMNTQIATAAEEQHQVAEDINRHISQIHGDAQLVAELANSARLDSQSLAGLSNELD
GLVRRFRT

Sequences:

>Translated_648_residues
MNIKQKLTWAFAIIACLPVVLVATLVVLNLRSDARDDFVDSSGREIRQVSNAMQLFFDGISQNVDYLAAQPLVKNADGSV
RSRMSANASDTSDGEIDKQLFALFEGLAKSHPAYSYVSYGLNSGGYAFWPGDPKMANYDPRTRPWYKTAMANPGKTLRTE
AYYWAGDDAVLVSTVRAVANQLGAQGGVVNIDVSLKQLTEIVKQIKLGESGYLMLMENTGTVLVDPKQPEHNFKRLDSLG
DGYAQLAKAGKGLVDIELNGERYMANVWPSEQLGWTFIGLIKQNDVMSSATKLTWLIAIIAAVLAVFFAVVGASFASLIV
RPIRSVASGLEGIAQGEGDLTKNLDIRGSDETAQLANWFNQFLTAIRSLIQHIGGAAGKILATSQSSTRVSGDMAEAAGR
QREAVDMVSTAFHEMVATANEVARSCSQAAESADSGQRQAREGQQQIDAAVHSVDQLSQELEQSAQSMQQLERDSNDIQS
ILGTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTADSTAEIDGLLGNLAKRTSAVTQQMRASLDVSQ
QSVARIGEARESFGQIRESVDVIRDMNTQIATAAEEQHQVAEDINRHISQIHGDAQLVAELANSARLDSQSLAGLSNELD
GLVRRFRT
>Mature_648_residues
MNIKQKLTWAFAIIACLPVVLVATLVVLNLRSDARDDFVDSSGREIRQVSNAMQLFFDGISQNVDYLAAQPLVKNADGSV
RSRMSANASDTSDGEIDKQLFALFEGLAKSHPAYSYVSYGLNSGGYAFWPGDPKMANYDPRTRPWYKTAMANPGKTLRTE
AYYWAGDDAVLVSTVRAVANQLGAQGGVVNIDVSLKQLTEIVKQIKLGESGYLMLMENTGTVLVDPKQPEHNFKRLDSLG
DGYAQLAKAGKGLVDIELNGERYMANVWPSEQLGWTFIGLIKQNDVMSSATKLTWLIAIIAAVLAVFFAVVGASFASLIV
RPIRSVASGLEGIAQGEGDLTKNLDIRGSDETAQLANWFNQFLTAIRSLIQHIGGAAGKILATSQSSTRVSGDMAEAAGR
QREAVDMVSTAFHEMVATANEVARSCSQAAESADSGQRQAREGQQQIDAAVHSVDQLSQELEQSAQSMQQLERDSNDIQS
ILGTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTADSTAEIDGLLGNLAKRTSAVTQQMRASLDVSQ
QSVARIGEARESFGQIRESVDVIRDMNTQIATAAEEQHQVAEDINRHISQIHGDAQLVAELANSARLDSQSLAGLSNELD
GLVRRFRT

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=331, Percent_Identity=30.2114803625378, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787690, Length=544, Percent_Identity=25.7352941176471, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1788194, Length=362, Percent_Identity=29.0055248618785, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788195, Length=280, Percent_Identity=30, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1789453, Length=314, Percent_Identity=29.9363057324841, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 69971; Mature: 69971

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKQKLTWAFAIIACLPVVLVATLVVLNLRSDARDDFVDSSGREIRQVSNAMQLFFDGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
SQNVDYLAAQPLVKNADGSVRSRMSANASDTSDGEIDKQLFALFEGLAKSHPAYSYVSYG
HCCHHHHHHCCHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHC
LNSGGYAFWPGDPKMANYDPRTRPWYKTAMANPGKTLRTEAYYWAGDDAVLVSTVRAVAN
CCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
QLGAQGGVVNIDVSLKQLTEIVKQIKLGESGYLMLMENTGTVLVDPKQPEHNFKRLDSLG
HHCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHCC
DGYAQLAKAGKGLVDIELNGERYMANVWPSEQLGWTFIGLIKQNDVMSSATKLTWLIAII
CHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHH
AAVLAVFFAVVGASFASLIVRPIRSVASGLEGIAQGEGDLTKNLDIRGSDETAQLANWFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
QFLTAIRSLIQHIGGAAGKILATSQSSTRVSGDMAEAAGRQREAVDMVSTAFHEMVATAN
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EVARSCSQAAESADSGQRQAREGQQQIDAAVHSVDQLSQELEQSAQSMQQLERDSNDIQS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
ILGTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTADSTAEIDGLLGN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHH
LAKRTSAVTQQMRASLDVSQQSVARIGEARESFGQIRESVDVIRDMNTQIATAAEEQHQV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AEDINRHISQIHGDAQLVAELANSARLDSQSLAGLSNELDGLVRRFRT
HHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIKQKLTWAFAIIACLPVVLVATLVVLNLRSDARDDFVDSSGREIRQVSNAMQLFFDGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
SQNVDYLAAQPLVKNADGSVRSRMSANASDTSDGEIDKQLFALFEGLAKSHPAYSYVSYG
HCCHHHHHHCCHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHC
LNSGGYAFWPGDPKMANYDPRTRPWYKTAMANPGKTLRTEAYYWAGDDAVLVSTVRAVAN
CCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
QLGAQGGVVNIDVSLKQLTEIVKQIKLGESGYLMLMENTGTVLVDPKQPEHNFKRLDSLG
HHCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHCC
DGYAQLAKAGKGLVDIELNGERYMANVWPSEQLGWTFIGLIKQNDVMSSATKLTWLIAII
CHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHH
AAVLAVFFAVVGASFASLIVRPIRSVASGLEGIAQGEGDLTKNLDIRGSDETAQLANWFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
QFLTAIRSLIQHIGGAAGKILATSQSSTRVSGDMAEAAGRQREAVDMVSTAFHEMVATAN
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EVARSCSQAAESADSGQRQAREGQQQIDAAVHSVDQLSQELEQSAQSMQQLERDSNDIQS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
ILGTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTADSTAEIDGLLGN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHH
LAKRTSAVTQQMRASLDVSQQSVARIGEARESFGQIRESVDVIRDMNTQIATAAEEQHQV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AEDINRHISQIHGDAQLVAELANSARLDSQSLAGLSNELDGLVRRFRT
HHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]