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The map label for this gene is hlyB [H]

Identifier: 77456678

GI number: 77456678

Start: 510651

End: 512588

Strand: Direct

Name: hlyB [H]

Synonym: Pfl01_0450

Alternate gene names: 77456678

Gene position: 510651-512588 (Clockwise)

Preceding gene: 77456677

Following gene: 77456681

Centisome position: 7.93

GC content: 62.44

Gene sequence:

>1938_bases
ATGCAGTTCTGGCGTCGCAGTATTCAATGGCAGTTGATCCTCGGCATGGGCACCGCCCTGCTGGTCAGCATTCTGATCGT
GGTTGGCATTTATACCCTGGTGGTCAACCGCCTCGCCCAGAGCTATCTGGTCGAACAGGCGCTGCCGTCGAGCATCGAAG
CGACGCGCAACGACATCGAACGAATCCTCGTTCAACCCCTCACCGCCGCCAAGGATATCGCCAGCAACACCATGGTCCGC
GACTGGCTGGCCAATGGTGAGGACTCCGCCAAAACCGCGGGTTTCGCGCAGTATCTGGAAGGCATCCGCGCCGAACACAA
GGCTTTTACTGCTTTGATCATCGGCACCGAATCCAATCACTACATCACCGAAAAAGGCCTGGATCGCACCCTCAGTCGCG
ACAAACCGGCCGATGCGTGGTTCTACTCCTTCCTCGACAGCAATCAGCCGCGAACCTTGAACATCGACAACGACGGGGCC
ACCGGAGAGCTGGCGCTGTTCATCGATTTGAAGGTGGAGCAGGCCGGCAAAGTGGTCGGTGTCGCGGGGCTCGGGCTGAG
CATGAAAGAGCTGTCGGAGCTGATTCACAACTTCAGCTTCGGCGAGCGCGGGAAGGTCTATCTCGTGCGTTCCGACGGTC
TTATCCAGGTCCATCCCGAGGCACAGTTCAGCGGCAAGCGCACCTTGAGCGAGCAGATCGGCGTCTCGGCAGCACAAGCG
GTCATGGGCCATAAAGTCGCCGCCAACAGCAGCTTTCAGCGCGACGGCGAAGATTTCCTCGCCTTCAGCCTGCCTTTGCG
CGATCTCGGCTGGACCCTGGTGGCCGAAGTGCCACGGTCGCAGATCTACGCCGAAGCCCGCCGGGCGATGTGGATGAGCA
GCGGCATCGGCCTGGTGGTGGCGCTGGTTTGCCTGGCGCTGGTGATCTGGCTGGCCCAGGGCTTGGTGCGACCGATTCGT
CAGGTAACAGCTGCATTGGTAGCAATCGGTAGCGGTGGTGGAGATTTGACTCATCGGTTAGATTCCAGCCGCGCCGATGA
ACTGGGCGACCTCGCCCGGGGCTTCAACCGTTTCCTCGACAGCCAGCGCGGGATGATCGGCGAAGTGCTGACCACCAGCG
TGCGTCTGCGCGTTGCCGTGGGCCAGGTGGCCAGGGTTGTGGATAACACCGCCGAGCGCTCCGGCCGCCAGCAGGAAATG
ACCGACATGGTTGCCACCGCCGTCCACGAAATGGGCCTGACCGTGCAGGAAATCGCCCAGAACGCCGGTAATGCGGCACT
CGCCTCGCAAACCGCCCGCGATGAAGCGATGCAGGCGCGGGAAGTGGTCGGCGGCTCGATTCGCCATATAGAAAGCATGT
CCGATGAAATTGGCGTCGCGGCGGGCGCGGTGGGTGAGCTGGCGCATCAAGTGGCGTCGATCGATCAGGTGCTGGCGGTG
ATTCGCGGGGTGTCCGAGCAGACCAACCTGCTGGCGTTGAACGCTGCCATCGAGGCTGCTCGAGCCGGCGATATGGGGCG
TGGTTTTGCAGTGGTGGCCGACGAGGTGCGGACATTGGCGCGCCGGACTCAGGCGTCTACCGACGAGATTCAGCAGATGA
TCGGCAGCCTTAAACAGGGCGCGGAGAATGCGGTGTCATCGATGCGCACCGGGCAGGCCGCGACGGGTACCGGAGTCGAA
TCGAGCCAGCGTACCGGGGCGTCTTTGACGGCGATTACCGGGCAGGTCGAGCGCATCAGCGACATGAACCATCAGGTGGC
GACAGCGACTGAGGAGCAGTCGGCGGTGACCGAGGAGATCAACCGCAACGTACAGGGCATTTCCGATCTGGCCCGGGCGA
CGGCGGGGGAGGTTCGGGCGTGTCGTGAGGATTGTCAGATGTTGCAGCGGCTGGCGGATGATCTGGCGCGGCAGATGGGT
GGGTTCAAGTTGAGCTGA

Upstream 100 bases:

>100_bases
TGGGGTTGCGCACAACCAAAGAATAAGATTGTCGATTGCGTTGTATACAATCGGCACGGCTGTTGCAGTGTTTCAGCCTC
TTATTCTTTGGGGGTGCTCC

Downstream 100 bases:

>100_bases
TGTGTCGTCAGATTGATCGTTCCCACGCTCTGCGTGGGAACGATCGCTAACGATCACCGTGGGATCAGAACCACGCATCC
TGCATTGCCAGACACGTATC

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MQFWRRSIQWQLILGMGTALLVSILIVVGIYTLVVNRLAQSYLVEQALPSSIEATRNDIERILVQPLTAAKDIASNTMVR
DWLANGEDSAKTAGFAQYLEGIRAEHKAFTALIIGTESNHYITEKGLDRTLSRDKPADAWFYSFLDSNQPRTLNIDNDGA
TGELALFIDLKVEQAGKVVGVAGLGLSMKELSELIHNFSFGERGKVYLVRSDGLIQVHPEAQFSGKRTLSEQIGVSAAQA
VMGHKVAANSSFQRDGEDFLAFSLPLRDLGWTLVAEVPRSQIYAEARRAMWMSSGIGLVVALVCLALVIWLAQGLVRPIR
QVTAALVAIGSGGGDLTHRLDSSRADELGDLARGFNRFLDSQRGMIGEVLTTSVRLRVAVGQVARVVDNTAERSGRQQEM
TDMVATAVHEMGLTVQEIAQNAGNAALASQTARDEAMQAREVVGGSIRHIESMSDEIGVAAGAVGELAHQVASIDQVLAV
IRGVSEQTNLLALNAAIEAARAGDMGRGFAVVADEVRTLARRTQASTDEIQQMIGSLKQGAENAVSSMRTGQAATGTGVE
SSQRTGASLTAITGQVERISDMNHQVATATEEQSAVTEEINRNVQGISDLARATAGEVRACREDCQMLQRLADDLARQMG
GFKLS

Sequences:

>Translated_645_residues
MQFWRRSIQWQLILGMGTALLVSILIVVGIYTLVVNRLAQSYLVEQALPSSIEATRNDIERILVQPLTAAKDIASNTMVR
DWLANGEDSAKTAGFAQYLEGIRAEHKAFTALIIGTESNHYITEKGLDRTLSRDKPADAWFYSFLDSNQPRTLNIDNDGA
TGELALFIDLKVEQAGKVVGVAGLGLSMKELSELIHNFSFGERGKVYLVRSDGLIQVHPEAQFSGKRTLSEQIGVSAAQA
VMGHKVAANSSFQRDGEDFLAFSLPLRDLGWTLVAEVPRSQIYAEARRAMWMSSGIGLVVALVCLALVIWLAQGLVRPIR
QVTAALVAIGSGGGDLTHRLDSSRADELGDLARGFNRFLDSQRGMIGEVLTTSVRLRVAVGQVARVVDNTAERSGRQQEM
TDMVATAVHEMGLTVQEIAQNAGNAALASQTARDEAMQAREVVGGSIRHIESMSDEIGVAAGAVGELAHQVASIDQVLAV
IRGVSEQTNLLALNAAIEAARAGDMGRGFAVVADEVRTLARRTQASTDEIQQMIGSLKQGAENAVSSMRTGQAATGTGVE
SSQRTGASLTAITGQVERISDMNHQVATATEEQSAVTEEINRNVQGISDLARATAGEVRACREDCQMLQRLADDLARQMG
GFKLS
>Mature_645_residues
MQFWRRSIQWQLILGMGTALLVSILIVVGIYTLVVNRLAQSYLVEQALPSSIEATRNDIERILVQPLTAAKDIASNTMVR
DWLANGEDSAKTAGFAQYLEGIRAEHKAFTALIIGTESNHYITEKGLDRTLSRDKPADAWFYSFLDSNQPRTLNIDNDGA
TGELALFIDLKVEQAGKVVGVAGLGLSMKELSELIHNFSFGERGKVYLVRSDGLIQVHPEAQFSGKRTLSEQIGVSAAQA
VMGHKVAANSSFQRDGEDFLAFSLPLRDLGWTLVAEVPRSQIYAEARRAMWMSSGIGLVVALVCLALVIWLAQGLVRPIR
QVTAALVAIGSGGGDLTHRLDSSRADELGDLARGFNRFLDSQRGMIGEVLTTSVRLRVAVGQVARVVDNTAERSGRQQEM
TDMVATAVHEMGLTVQEIAQNAGNAALASQTARDEAMQAREVVGGSIRHIESMSDEIGVAAGAVGELAHQVASIDQVLAV
IRGVSEQTNLLALNAAIEAARAGDMGRGFAVVADEVRTLARRTQASTDEIQQMIGSLKQGAENAVSSMRTGQAATGTGVE
SSQRTGASLTAITGQVERISDMNHQVATATEEQSAVTEEINRNVQGISDLARATAGEVRACREDCQMLQRLADDLARQMG
GFKLS

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=311, Percent_Identity=29.5819935691318, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788195, Length=280, Percent_Identity=31.7857142857143, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788194, Length=348, Percent_Identity=26.1494252873563, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787690, Length=327, Percent_Identity=27.217125382263, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1789453, Length=323, Percent_Identity=27.5541795665635, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 69330; Mature: 69330

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFWRRSIQWQLILGMGTALLVSILIVVGIYTLVVNRLAQSYLVEQALPSSIEATRNDIE
CCHHHHCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RILVQPLTAAKDIASNTMVRDWLANGEDSAKTAGFAQYLEGIRAEHKAFTALIIGTESNH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCC
YITEKGLDRTLSRDKPADAWFYSFLDSNQPRTLNIDNDGATGELALFIDLKVEQAGKVVG
EECHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEEEEECCCCCEEE
VAGLGLSMKELSELIHNFSFGERGKVYLVRSDGLIQVHPEAQFSGKRTLSEQIGVSAAQA
EECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHCHHHHHH
VMGHKVAANSSFQRDGEDFLAFSLPLRDLGWTLVAEVPRSQIYAEARRAMWMSSGIGLVV
HHHHHHHCCCCCCCCCCHHEEEECCHHHHCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
ALVCLALVIWLAQGLVRPIRQVTAALVAIGSGGGDLTHRLDSSRADELGDLARGFNRFLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
SQRGMIGEVLTTSVRLRVAVGQVARVVDNTAERSGRQQEMTDMVATAVHEMGLTVQEIAQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHH
NAGNAALASQTARDEAMQAREVVGGSIRHIESMSDEIGVAAGAVGELAHQVASIDQVLAV
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRGVSEQTNLLALNAAIEAARAGDMGRGFAVVADEVRTLARRTQASTDEIQQMIGSLKQG
HHCCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AENAVSSMRTGQAATGTGVESSQRTGASLTAITGQVERISDMNHQVATATEEQSAVTEEI
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHH
NRNVQGISDLARATAGEVRACREDCQMLQRLADDLARQMGGFKLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQFWRRSIQWQLILGMGTALLVSILIVVGIYTLVVNRLAQSYLVEQALPSSIEATRNDIE
CCHHHHCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RILVQPLTAAKDIASNTMVRDWLANGEDSAKTAGFAQYLEGIRAEHKAFTALIIGTESNH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCC
YITEKGLDRTLSRDKPADAWFYSFLDSNQPRTLNIDNDGATGELALFIDLKVEQAGKVVG
EECHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEEEEECCCCCEEE
VAGLGLSMKELSELIHNFSFGERGKVYLVRSDGLIQVHPEAQFSGKRTLSEQIGVSAAQA
EECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHCHHHHHH
VMGHKVAANSSFQRDGEDFLAFSLPLRDLGWTLVAEVPRSQIYAEARRAMWMSSGIGLVV
HHHHHHHCCCCCCCCCCHHEEEECCHHHHCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
ALVCLALVIWLAQGLVRPIRQVTAALVAIGSGGGDLTHRLDSSRADELGDLARGFNRFLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
SQRGMIGEVLTTSVRLRVAVGQVARVVDNTAERSGRQQEMTDMVATAVHEMGLTVQEIAQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHH
NAGNAALASQTARDEAMQAREVVGGSIRHIESMSDEIGVAAGAVGELAHQVASIDQVLAV
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRGVSEQTNLLALNAAIEAARAGDMGRGFAVVADEVRTLARRTQASTDEIQQMIGSLKQG
HHCCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AENAVSSMRTGQAATGTGVESSQRTGASLTAITGQVERISDMNHQVATATEEQSAVTEEI
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHH
NRNVQGISDLARATAGEVRACREDCQMLQRLADDLARQMGGFKLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]