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The map label for this gene is pilQ [H]

Identifier: 77456637

GI number: 77456637

Start: 464468

End: 466546

Strand: Direct

Name: pilQ [H]

Synonym: Pfl01_0409

Alternate gene names: 77456637

Gene position: 464468-466546 (Clockwise)

Preceding gene: 77456636

Following gene: 77456638

Centisome position: 7.21

GC content: 60.56

Gene sequence:

>2079_bases
ATGAACAGGATTTTCTCCACCCTCGGTTTCTCGCTATGGATAGCGCTGCTTTCGCCGATGGTACAGGCAGCCAATCTGAA
GGCGCTGGACGTCGCGGCACTGCCGGGCGACCGGGTCGAGCTGAAGCTGTCGTTCGATGGCCCACCTCCGCAGCCAAAGG
GTTACACCACCGATTCGCCGGCGCGGATTGCCCTCGATCTGCCGGGTGTTGCCAGTCAGCTGGCGAGCAAGACTCGCGAC
CTGGGCAGTGGCAATGCCCGTACGGCCACGGTGGTCGAGGCCAATAATCGGACGCGGCTGATCATCAGCCTGACGCAACT
GGCGCCGTACGACACCCGGGTCGAAGGCAATACGGTGTTTGTGGTGGTCGGGCAGGGCAGCAAAGCCGCGGCACCGCGTA
CGGCAGCTCGTGCACCGCGTGCGGCACCTGCGGCAGCGCCGGTCCGCACGTATACGCCGACCGCCAGGGCCATTCGCGGC
GTGGATTTCCAGCGTGGCACGGCGGGTGAGGGCAATGTGGTCATCGACTTGTCCGACCCGGCTATCGCCCCGGACATTCA
GGAGCACGACGGCAAGATCATCCTCAATTTCGCCCGTACCCAACTGCCCGAACCGCTGCGGGTGCGCCTCGATGTCAAGG
ATTTCGCCACCCCGGTGCAGTTCGTCAATGCCGGCGTCAGTGGTGATCGCGCGACGATCACCGTCGAACCCAGCGGTACG
TTCGACTATTCCACCTACCAGACCGACAACAAGCTGACCGTCAGTATCCGGCCGTTGACCGTCGATGACCTGCAAAAGCG
CAACGCCGACCGCAACAGCTATAACGGCGAAAAGCTCTCTCTCAACTTCCAGGACATCGATGTGCGTTCGGTGCTGCAAC
TGATCGCCGACTTCACCAACCTCAATCTGGTAGCCAGCGATACGGTACAGGGCGGGATCACCTTGCGCCTGCAAAACGTG
CCGTGGGATCAGGCGCTGGATCTGGTGCTCAAGACCAAGGGGCTGGACAAGCGCAAGGTCGGCAATGTGTTGCTGGTGGC
GCCGGCGGATGAAATCGCCGCCCGCGAACGGCAGGAACTGGAATCGCAAAAACAGATCGCCGAGCTGGCACCGCTGCGCC
GCGAGCTGCTGCAAGTGAACTACGCCAAGGCTGCGGACATCGCCAAGCTGTTCCAGTCGGTCACCAGTGCCGAGGCCAAG
GTCGACGAACGGGGTTCGATCACCGTCGATGAGCGGACCAACAACATCATTGCCTACCAGACTCAGGATCGCCTCGACGA
ACTGCGGCGGATTGTGGCGCAGCTGGATATTCCGGTGCGTCAGGTGATGATCGAGGCGCGGATCGTCGAGGCCAACGTCG
ATTACGACAAGAGCTTGGGCGTGCGCTGGGGCGGTTCGATTCAGAACAAGGGCAACTGGAACACTTCCGGGGTCAGCAAC
GGTTCGTCGACCACCATTGGCACGCCGGGCAGCACCAGCACCAACTCGCCGTTCGTCGACATGGGCACGGTCAACAACAC
GTCCGGGATCGGCATCGCGTTCATCACCGACAACGTCTTGCTCGACCTTGAGCTGACCGCGATGGAGAAGACCGGCAATG
GCGAAATCGTCTCGCAGCCCAAGGTGGTCACGTCCGACAAGGAAACCGCGAAGATCCTCAAGGGCACCGAGATTCCGTAT
CAGGAAGCCAGCTCCAGCGGTGCTACGTCGGTGTCCTTCAAGGAGGCGTCGCTGTCGCTGGAAGTGACGCCGCAGATCAC
CCCGGACAACCGCATCATCATGGAGGTCAAGGTCACCAAGGACGAACCGGACTACCTGAACAAAGTGCAGGATGTACCGC
CGATCAAGAAGAACGAGGTCAATGCCAAGGTGCTGGTGAACGACGGCGAGACCATCGTGATCGGGGGCGTTTTCTCAAAT
ACTCAAAGCAAGGTCGTAGATAAGGTGCCATTTCTTGGCGATGTGCCGTATCTTGGCCGCCTTTTCCGGCGTGATGTGGT
TTCGGAGAAAAAATCCGAGCTGCTGGTATTTCTCACTCCGCGTATCATGAATAACCAGGCGATTGCTGTGAGTCGTTGA

Upstream 100 bases:

>100_bases
AGGTCGATGTGGTGGAAATCGTTCCGGATGGCCAGGGCGCCTGGCTTGAGCGGCCGCGCACCATTCCTTTGAAAGAGCAT
TCATAAGTGGAAGTCGAACA

Downstream 100 bases:

>100_bases
TTCTGTGCGAAATTTGATTCTTGTAGGACCGATGGGGGCTGGAAAAAGCACCATCGGCCGATTACTGGCCAAAGAGCTGC
GCCTGCCGTTCAAGGATTCC

Product: type II and III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MNRIFSTLGFSLWIALLSPMVQAANLKALDVAALPGDRVELKLSFDGPPPQPKGYTTDSPARIALDLPGVASQLASKTRD
LGSGNARTATVVEANNRTRLIISLTQLAPYDTRVEGNTVFVVVGQGSKAAAPRTAARAPRAAPAAAPVRTYTPTARAIRG
VDFQRGTAGEGNVVIDLSDPAIAPDIQEHDGKIILNFARTQLPEPLRVRLDVKDFATPVQFVNAGVSGDRATITVEPSGT
FDYSTYQTDNKLTVSIRPLTVDDLQKRNADRNSYNGEKLSLNFQDIDVRSVLQLIADFTNLNLVASDTVQGGITLRLQNV
PWDQALDLVLKTKGLDKRKVGNVLLVAPADEIAARERQELESQKQIAELAPLRRELLQVNYAKAADIAKLFQSVTSAEAK
VDERGSITVDERTNNIIAYQTQDRLDELRRIVAQLDIPVRQVMIEARIVEANVDYDKSLGVRWGGSIQNKGNWNTSGVSN
GSSTTIGTPGSTSTNSPFVDMGTVNNTSGIGIAFITDNVLLDLELTAMEKTGNGEIVSQPKVVTSDKETAKILKGTEIPY
QEASSSGATSVSFKEASLSLEVTPQITPDNRIIMEVKVTKDEPDYLNKVQDVPPIKKNEVNAKVLVNDGETIVIGGVFSN
TQSKVVDKVPFLGDVPYLGRLFRRDVVSEKKSELLVFLTPRIMNNQAIAVSR

Sequences:

>Translated_692_residues
MNRIFSTLGFSLWIALLSPMVQAANLKALDVAALPGDRVELKLSFDGPPPQPKGYTTDSPARIALDLPGVASQLASKTRD
LGSGNARTATVVEANNRTRLIISLTQLAPYDTRVEGNTVFVVVGQGSKAAAPRTAARAPRAAPAAAPVRTYTPTARAIRG
VDFQRGTAGEGNVVIDLSDPAIAPDIQEHDGKIILNFARTQLPEPLRVRLDVKDFATPVQFVNAGVSGDRATITVEPSGT
FDYSTYQTDNKLTVSIRPLTVDDLQKRNADRNSYNGEKLSLNFQDIDVRSVLQLIADFTNLNLVASDTVQGGITLRLQNV
PWDQALDLVLKTKGLDKRKVGNVLLVAPADEIAARERQELESQKQIAELAPLRRELLQVNYAKAADIAKLFQSVTSAEAK
VDERGSITVDERTNNIIAYQTQDRLDELRRIVAQLDIPVRQVMIEARIVEANVDYDKSLGVRWGGSIQNKGNWNTSGVSN
GSSTTIGTPGSTSTNSPFVDMGTVNNTSGIGIAFITDNVLLDLELTAMEKTGNGEIVSQPKVVTSDKETAKILKGTEIPY
QEASSSGATSVSFKEASLSLEVTPQITPDNRIIMEVKVTKDEPDYLNKVQDVPPIKKNEVNAKVLVNDGETIVIGGVFSN
TQSKVVDKVPFLGDVPYLGRLFRRDVVSEKKSELLVFLTPRIMNNQAIAVSR
>Mature_692_residues
MNRIFSTLGFSLWIALLSPMVQAANLKALDVAALPGDRVELKLSFDGPPPQPKGYTTDSPARIALDLPGVASQLASKTRD
LGSGNARTATVVEANNRTRLIISLTQLAPYDTRVEGNTVFVVVGQGSKAAAPRTAARAPRAAPAAAPVRTYTPTARAIRG
VDFQRGTAGEGNVVIDLSDPAIAPDIQEHDGKIILNFARTQLPEPLRVRLDVKDFATPVQFVNAGVSGDRATITVEPSGT
FDYSTYQTDNKLTVSIRPLTVDDLQKRNADRNSYNGEKLSLNFQDIDVRSVLQLIADFTNLNLVASDTVQGGITLRLQNV
PWDQALDLVLKTKGLDKRKVGNVLLVAPADEIAARERQELESQKQIAELAPLRRELLQVNYAKAADIAKLFQSVTSAEAK
VDERGSITVDERTNNIIAYQTQDRLDELRRIVAQLDIPVRQVMIEARIVEANVDYDKSLGVRWGGSIQNKGNWNTSGVSN
GSSTTIGTPGSTSTNSPFVDMGTVNNTSGIGIAFITDNVLLDLELTAMEKTGNGEIVSQPKVVTSDKETAKILKGTEIPY
QEASSSGATSVSFKEASLSLEVTPQITPDNRIIMEVKVTKDEPDYLNKVQDVPPIKKNEVNAKVLVNDGETIVIGGVFSN
TQSKVVDKVPFLGDVPYLGRLFRRDVVSEKKSELLVFLTPRIMNNQAIAVSR

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=420, Percent_Identity=37.6190476190476, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI87082242, Length=329, Percent_Identity=28.2674772036474, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 75024; Mature: 75024

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIFSTLGFSLWIALLSPMVQAANLKALDVAALPGDRVELKLSFDGPPPQPKGYTTDSP
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCC
ARIALDLPGVASQLASKTRDLGSGNARTATVVEANNRTRLIISLTQLAPYDTRVEGNTVF
CEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCEECCCEEE
VVVGQGSKAAAPRTAARAPRAAPAAAPVRTYTPTARAIRGVDFQRGTAGEGNVVIDLSDP
EEECCCCCCCCCCHHHCCCCCCCCCCCCEECCCHHHHHCCCCCCCCCCCCCCEEEEECCC
AIAPDIQEHDGKIILNFARTQLPEPLRVRLDVKDFATPVQFVNAGVSGDRATITVEPSGT
CCCCCHHHCCCEEEEEEHHHCCCCCEEEEEEHHHHCCHHHHHHCCCCCCEEEEEECCCCC
FDYSTYQTDNKLTVSIRPLTVDDLQKRNADRNSYNGEKLSLNFQDIDVRSVLQLIADFTN
CCCEEEECCCEEEEEEECCCHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCC
LNLVASDTVQGGITLRLQNVPWDQALDLVLKTKGLDKRKVGNVLLVAPADEIAARERQEL
CEEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHCCEEEEECCHHHHHHHHHHH
ESQKQIAELAPLRRELLQVNYAKAADIAKLFQSVTSAEAKVDERGSITVDERTNNIIAYQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEE
TQDRLDELRRIVAQLDIPVRQVMIEARIVEANVDYDKSLGVRWGGSIQNKGNWNTSGVSN
CHHHHHHHHHHHHHCCCCHHHHEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCC
GSSTTIGTPGSTSTNSPFVDMGTVNNTSGIGIAFITDNVLLDLELTAMEKTGNGEIVSQP
CCCCEECCCCCCCCCCCEEEECCCCCCCCCEEEEEECCEEEEEEEEEEEECCCCCEEECC
KVVTSDKETAKILKGTEIPYQEASSSGATSVSFKEASLSLEVTPQITPDNRIIMEVKVTK
EEEECCHHHHHHHCCCCCCHHHCCCCCCCEEEEEEEEEEEEECCEECCCCEEEEEEEECC
DEPDYLNKVQDVPPIKKNEVNAKVLVNDGETIVIGGVFSNTQSKVVDKVPFLGDVPYLGR
CCCHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEEECCCHHHHHHCCCCCCCCHHHHH
LFRRDVVSEKKSELLVFLTPRIMNNQAIAVSR
HHHHHHHCCCCCCEEEEECCEECCCCEEEEEC
>Mature Secondary Structure
MNRIFSTLGFSLWIALLSPMVQAANLKALDVAALPGDRVELKLSFDGPPPQPKGYTTDSP
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCC
ARIALDLPGVASQLASKTRDLGSGNARTATVVEANNRTRLIISLTQLAPYDTRVEGNTVF
CEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCEECCCEEE
VVVGQGSKAAAPRTAARAPRAAPAAAPVRTYTPTARAIRGVDFQRGTAGEGNVVIDLSDP
EEECCCCCCCCCCHHHCCCCCCCCCCCCEECCCHHHHHCCCCCCCCCCCCCCEEEEECCC
AIAPDIQEHDGKIILNFARTQLPEPLRVRLDVKDFATPVQFVNAGVSGDRATITVEPSGT
CCCCCHHHCCCEEEEEEHHHCCCCCEEEEEEHHHHCCHHHHHHCCCCCCEEEEEECCCCC
FDYSTYQTDNKLTVSIRPLTVDDLQKRNADRNSYNGEKLSLNFQDIDVRSVLQLIADFTN
CCCEEEECCCEEEEEEECCCHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCC
LNLVASDTVQGGITLRLQNVPWDQALDLVLKTKGLDKRKVGNVLLVAPADEIAARERQEL
CEEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHCCEEEEECCHHHHHHHHHHH
ESQKQIAELAPLRRELLQVNYAKAADIAKLFQSVTSAEAKVDERGSITVDERTNNIIAYQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEE
TQDRLDELRRIVAQLDIPVRQVMIEARIVEANVDYDKSLGVRWGGSIQNKGNWNTSGVSN
CHHHHHHHHHHHHHCCCCHHHHEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCC
GSSTTIGTPGSTSTNSPFVDMGTVNNTSGIGIAFITDNVLLDLELTAMEKTGNGEIVSQP
CCCCEECCCCCCCCCCCEEEECCCCCCCCCEEEEEECCEEEEEEEEEEEECCCCCEEECC
KVVTSDKETAKILKGTEIPYQEASSSGATSVSFKEASLSLEVTPQITPDNRIIMEVKVTK
EEEECCHHHHHHHCCCCCCHHHCCCCCCCEEEEEEEEEEEEECCEECCCCEEEEEEEECC
DEPDYLNKVQDVPPIKKNEVNAKVLVNDGETIVIGGVFSNTQSKVVDKVPFLGDVPYLGR
CCCHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEEECCCHHHHHHCCCCCCCCHHHHH
LFRRDVVSEKKSELLVFLTPRIMNNQAIAVSR
HHHHHHHCCCCCCEEEEECCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]