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The map label for this gene is yrkH [H]

Identifier: 77454787

GI number: 77454787

Start: 204279

End: 205673

Strand: Direct

Name: yrkH [H]

Synonym: pREL1_0220

Alternate gene names: 77454787

Gene position: 204279-205673 (Clockwise)

Preceding gene: 77454784

Following gene: 77454788

Centisome position: 75.22

GC content: 65.09

Gene sequence:

>1395_bases
ATGCTTCTCGAACGCATCTACGACGAAGACCTCGCCCAAGCCGGATACTTCATCGGCTGTCAGGCCAAGGGAGAGGCAGT
GGTGGTCGACGCCCGCCGCGACATCGGTGTGTACCTGGACCTGGCCGATCGGCATGGCATGACCATCACCGCCGTGACCG
AGACCCACATCCATGCCGACTACCTGTCCGGCACCCGCGAGTTGGCCAAGGCCACCGGCGCGACCACCTACGTCTCAGGA
GAGGGCGGCGACGACTGGCAGTACGGCTTCGAAGCCGAACGCCTCCACGATGGCGACACGCTGACTCTGGGCAACATCAC
CGTGCAAGCCGTTCACACGCCCGGCCATACCCCGGAGCACCTCTCGTTCCTGGTAACCGACGGTGCCTTCGCCGACGCTC
CGGGATACATGTTGACGGGCGACTTCGTCTTTGCCGGCGATCTCGGCCGGCCGGACCTACTCGACGAGGCCGCCGACGGT
GTCGACACCCGTTTCGAGGGTGCCAAACAGATCTTCCGCAGTCTGAAGCGATCGTTCGTCACGCAGCCGGATCATATCCA
GGTCTTTCCGGGTCACGGTTCGGGCAGCGCCTGCGGAAAAGCTCTCGGCGCGCTCCCGTCGACCAGCGTCGGCTACGAAC
GCCGTTTCGCTTGGTGGGCCGGGTACGTCGAGCGCGACGACGAGCAGGGCTTCGTCGATGAGATGCTCGACGGCCAACCG
GACGCACACGCCTACTTCGGCCGGATGAAGCGTCAGAACAAGCAGGGCCCGGTCGTTCTCGGGCCACTCTCTCCACTGCA
CGAGTACGACTCCGCAGAATTGGCACGCGCCCTGGATTCCGACGAGGTCGTCCTCCTCGACACCCGCGGCCAAGATGAGG
TGCACGTCGGCACTGTCCCCGGAGCGCTCAACATCCCCGGCCTCAGCAAGGCAGCCTCGTTCGGTGCCTGGGTCTACGAC
CCCGAGCGAGAGGACACTCCACTGGTGGTGCTCGCCGAGGACTGTAATGCCGCCGACGAGCTACGTGATCACCTGCTGCG
GGTCGGCATCGATACGGTGACCGGGTACGTCACAAGTCTACGAGGCCTCCCCATGACGACGCCCGAGACGATCGGGGCGG
ACGAGCTGGATTCGTTCGACCCGGCAATGGTGCTGGACGTGCGCAACAAGACCGAACACGCCGACGGCCACATACCTGGC
TCCGAACAGCTCAGCGGCGGCCGATTGTTGTGGAACCTCGACGGACTACCCACGGGCGGTCCGATCGTGACCTATTGCCA
GAGCGGCGTCCGCAACGCGGTCGCAGCCAGCGCACTGCGTCGCGCCGGCTACCATGTCGTCGAACTTGAGGGCAGCTACG
CCGCCTGGGCCGAGCACAACCTCGAAACAGTCTGA

Upstream 100 bases:

>100_bases
CGTGCGCCATGGCGCACAGAACCTACTGAAAATACCCCACCGGGTACCATGGATTGTTGACACCTGCACGACCGCCGCCA
CGATCGACAAGGAGATTTCG

Downstream 100 bases:

>100_bases
CCGGACACACCCCGAACAGGGGCCGTCGTACCGTCCGCCCCCGGTTCGCTGCTTAGCTTGTCTGTAAGGCTCGTCGAGCC
ACCGATGGCGGAGCGGACCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MLLERIYDEDLAQAGYFIGCQAKGEAVVVDARRDIGVYLDLADRHGMTITAVTETHIHADYLSGTRELAKATGATTYVSG
EGGDDWQYGFEAERLHDGDTLTLGNITVQAVHTPGHTPEHLSFLVTDGAFADAPGYMLTGDFVFAGDLGRPDLLDEAADG
VDTRFEGAKQIFRSLKRSFVTQPDHIQVFPGHGSGSACGKALGALPSTSVGYERRFAWWAGYVERDDEQGFVDEMLDGQP
DAHAYFGRMKRQNKQGPVVLGPLSPLHEYDSAELARALDSDEVVLLDTRGQDEVHVGTVPGALNIPGLSKAASFGAWVYD
PEREDTPLVVLAEDCNAADELRDHLLRVGIDTVTGYVTSLRGLPMTTPETIGADELDSFDPAMVLDVRNKTEHADGHIPG
SEQLSGGRLLWNLDGLPTGGPIVTYCQSGVRNAVAASALRRAGYHVVELEGSYAAWAEHNLETV

Sequences:

>Translated_464_residues
MLLERIYDEDLAQAGYFIGCQAKGEAVVVDARRDIGVYLDLADRHGMTITAVTETHIHADYLSGTRELAKATGATTYVSG
EGGDDWQYGFEAERLHDGDTLTLGNITVQAVHTPGHTPEHLSFLVTDGAFADAPGYMLTGDFVFAGDLGRPDLLDEAADG
VDTRFEGAKQIFRSLKRSFVTQPDHIQVFPGHGSGSACGKALGALPSTSVGYERRFAWWAGYVERDDEQGFVDEMLDGQP
DAHAYFGRMKRQNKQGPVVLGPLSPLHEYDSAELARALDSDEVVLLDTRGQDEVHVGTVPGALNIPGLSKAASFGAWVYD
PEREDTPLVVLAEDCNAADELRDHLLRVGIDTVTGYVTSLRGLPMTTPETIGADELDSFDPAMVLDVRNKTEHADGHIPG
SEQLSGGRLLWNLDGLPTGGPIVTYCQSGVRNAVAASALRRAGYHVVELEGSYAAWAEHNLETV
>Mature_464_residues
MLLERIYDEDLAQAGYFIGCQAKGEAVVVDARRDIGVYLDLADRHGMTITAVTETHIHADYLSGTRELAKATGATTYVSG
EGGDDWQYGFEAERLHDGDTLTLGNITVQAVHTPGHTPEHLSFLVTDGAFADAPGYMLTGDFVFAGDLGRPDLLDEAADG
VDTRFEGAKQIFRSLKRSFVTQPDHIQVFPGHGSGSACGKALGALPSTSVGYERRFAWWAGYVERDDEQGFVDEMLDGQP
DAHAYFGRMKRQNKQGPVVLGPLSPLHEYDSAELARALDSDEVVLLDTRGQDEVHVGTVPGALNIPGLSKAASFGAWVYD
PEREDTPLVVLAEDCNAADELRDHLLRVGIDTVTGYVTSLRGLPMTTPETIGADELDSFDPAMVLDVRNKTEHADGHIPG
SEQLSGGRLLWNLDGLPTGGPIVTYCQSGVRNAVAASALRRAGYHVVELEGSYAAWAEHNLETV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1787158, Length=220, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221330176, Length=198, Percent_Identity=23.7373737373737, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 50099; Mature: 50099

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLERIYDEDLAQAGYFIGCQAKGEAVVVDARRDIGVYLDLADRHGMTITAVTETHIHAD
CCHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCEEEEEECCCCCCEEEEEEECEEEHH
YLSGTRELAKATGATTYVSGEGGDDWQYGFEAERLHDGDTLTLGNITVQAVHTPGHTPEH
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCCEEEECCEEEEEEECCCCCCCC
LSFLVTDGAFADAPGYMLTGDFVFAGDLGRPDLLDEAADGVDTRFEGAKQIFRSLKRSFV
EEEEEECCCCCCCCCEEEECCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
TQPDHIQVFPGHGSGSACGKALGALPSTSVGYERRFAWWAGYVERDDEQGFVDEMLDGQP
CCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCHHEEEEEECCCCCCCCCCHHHHHHCCCC
DAHAYFGRMKRQNKQGPVVLGPLSPLHEYDSAELARALDSDEVVLLDTRGQDEVHVGTVP
CHHHHHHHHHHCCCCCCEEECCCCHHHHCCHHHHHHHCCCCCEEEEECCCCCCEEEECCC
GALNIPGLSKAASFGAWVYDPEREDTPLVVLAEDCNAADELRDHLLRVGIDTVTGYVTSL
CCCCCCCCHHHHHCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGLPMTTPETIGADELDSFDPAMVLDVRNKTEHADGHIPGSEQLSGGRLLWNLDGLPTGG
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
PIVTYCQSGVRNAVAASALRRAGYHVVELEGSYAAWAEHNLETV
CHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEHHCCCCCCC
>Mature Secondary Structure
MLLERIYDEDLAQAGYFIGCQAKGEAVVVDARRDIGVYLDLADRHGMTITAVTETHIHAD
CCHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCEEEEEECCCCCCEEEEEEECEEEHH
YLSGTRELAKATGATTYVSGEGGDDWQYGFEAERLHDGDTLTLGNITVQAVHTPGHTPEH
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCCEEEECCEEEEEEECCCCCCCC
LSFLVTDGAFADAPGYMLTGDFVFAGDLGRPDLLDEAADGVDTRFEGAKQIFRSLKRSFV
EEEEEECCCCCCCCCEEEECCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
TQPDHIQVFPGHGSGSACGKALGALPSTSVGYERRFAWWAGYVERDDEQGFVDEMLDGQP
CCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCHHEEEEEECCCCCCCCCCHHHHHHCCCC
DAHAYFGRMKRQNKQGPVVLGPLSPLHEYDSAELARALDSDEVVLLDTRGQDEVHVGTVP
CHHHHHHHHHHCCCCCCEEECCCCHHHHCCHHHHHHHCCCCCEEEEECCCCCCEEEECCC
GALNIPGLSKAASFGAWVYDPEREDTPLVVLAEDCNAADELRDHLLRVGIDTVTGYVTSL
CCCCCCCCHHHHHCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGLPMTTPETIGADELDSFDPAMVLDVRNKTEHADGHIPGSEQLSGGRLLWNLDGLPTGG
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
PIVTYCQSGVRNAVAASALRRAGYHVVELEGSYAAWAEHNLETV
CHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]