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The map label for this gene is 77454671

Identifier: 77454671

GI number: 77454671

Start: 101678

End: 102517

Strand: Direct

Name: 77454671

Synonym: pREL1_0104

Alternate gene names: NA

Gene position: 101678-102517 (Clockwise)

Preceding gene: 77454670

Following gene: 77454672

Centisome position: 37.44

GC content: 61.07

Gene sequence:

>840_bases
ATGCTCTGGTCGCGCAACGGTAACAACATCAGCGCATCATTCCCCGAGATCGTCGATGCACTCCGCTCGGTGCTCGAACA
CCGAGAAACCGTCCTCGACGGGGAAATCGTCGCCCTCGGACCGGACGGTGTGCCGTCCTTCTCCCTGTTGCAACGCCGGA
TGCACGTGCTCAGACCCACCGCACAGCTCCGCAACGAGGCCGTGACCTCGTATTACGTGTTCGACGTCCTCGACATCGAC
GGCACATCAACCAGCGATCTGCCCTATCTCGAGCGCCGCGAGGCGCTCGCCAATCTCAGTCTCGAACACCCGCGCATCAA
AGTCCCACCGCACTGGCTCAACGTCGACGGACCGACCATGCTCGAGGTGGCGCGCAAACACCATCTGGAAGGTATCGTGG
CCAAGAACATCTCCTCGATCTATCAGTCCGGCAAGCGATCTCGCGACTGGATCAAAACGCCTCTGAGAGCTAATTGTGAG
GCCGTAGTGTGCGGCTTCCTCCCCGGCTCGGGAGGTGCGGCAGGAGGAGTCGGATCGTTGATCCTCGGCGCTCACGACGA
TTCAAGGGTCCTCAGATATATCGGAAACGTTGGTACGGGTCTGACCGATCGACAGCGGCGCGAACTACGAGACAAGCTCG
TCGAACTCCATCAGCCGATCAGCCCGTTCACTATCGAGCCGCCGCGAGCGGTCACCCGCAATGCATCCTGGTCGAGGCCG
ATCCTTGTCTGCGACGTGGAATACCGCGAGTACACCGGTGGCAGCCTTCGGCACCCATCCTTTCGAGGGCTGCGCAACGA
CAAGACCGCCGATGAGGTCAACGTACCGGGTCGTCACTGA

Upstream 100 bases:

>100_bases
CAGTTCGACCAGGCGTCGCTACGCACTAGTTCAGATAAGGGCCTTCGAATCGAAATGGGATGGCCAAAGAGCAATAGCAA
CAACAGGTTCCGTGCATCCG

Downstream 100 bases:

>100_bases
GTCACTGCAACAGTGCAAATCAGAAAGATTCGCTGATGGACAATTTGGTGGTTGTATTGGAGCCCGTTTCCGCAGCCTAA
GTAAACGACGGGATCATCTA

Product: putative DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MLWSRNGNNISASFPEIVDALRSVLEHRETVLDGEIVALGPDGVPSFSLLQRRMHVLRPTAQLRNEAVTSYYVFDVLDID
GTSTSDLPYLERREALANLSLEHPRIKVPPHWLNVDGPTMLEVARKHHLEGIVAKNISSIYQSGKRSRDWIKTPLRANCE
AVVCGFLPGSGGAAGGVGSLILGAHDDSRVLRYIGNVGTGLTDRQRRELRDKLVELHQPISPFTIEPPRAVTRNASWSRP
ILVCDVEYREYTGGSLRHPSFRGLRNDKTADEVNVPGRH

Sequences:

>Translated_279_residues
MLWSRNGNNISASFPEIVDALRSVLEHRETVLDGEIVALGPDGVPSFSLLQRRMHVLRPTAQLRNEAVTSYYVFDVLDID
GTSTSDLPYLERREALANLSLEHPRIKVPPHWLNVDGPTMLEVARKHHLEGIVAKNISSIYQSGKRSRDWIKTPLRANCE
AVVCGFLPGSGGAAGGVGSLILGAHDDSRVLRYIGNVGTGLTDRQRRELRDKLVELHQPISPFTIEPPRAVTRNASWSRP
ILVCDVEYREYTGGSLRHPSFRGLRNDKTADEVNVPGRH
>Mature_279_residues
MLWSRNGNNISASFPEIVDALRSVLEHRETVLDGEIVALGPDGVPSFSLLQRRMHVLRPTAQLRNEAVTSYYVFDVLDID
GTSTSDLPYLERREALANLSLEHPRIKVPPHWLNVDGPTMLEVARKHHLEGIVAKNISSIYQSGKRSRDWIKTPLRANCE
AVVCGFLPGSGGAAGGVGSLILGAHDDSRVLRYIGNVGTGLTDRQRRELRDKLVELHQPISPFTIEPPRAVTRNASWSRP
ILVCDVEYREYTGGSLRHPSFRGLRNDKTADEVNVPGRH

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320038, Length=311, Percent_Identity=25.4019292604502, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762424, Length=315, Percent_Identity=24.4444444444444, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 31037; Mature: 31037

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWSRNGNNISASFPEIVDALRSVLEHRETVLDGEIVALGPDGVPSFSLLQRRMHVLRPT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCH
AQLRNEAVTSYYVFDVLDIDGTSTSDLPYLERREALANLSLEHPRIKVPPHWLNVDGPTM
HHHHHHHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCEECCCCHHH
LEVARKHHLEGIVAKNISSIYQSGKRSRDWIKTPLRANCEAVVCGFLPGSGGAAGGVGSL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCE
ILGAHDDSRVLRYIGNVGTGLTDRQRRELRDKLVELHQPISPFTIEPPRAVTRNASWSRP
EEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCC
ILVCDVEYREYTGGSLRHPSFRGLRNDKTADEVNVPGRH
EEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLWSRNGNNISASFPEIVDALRSVLEHRETVLDGEIVALGPDGVPSFSLLQRRMHVLRPT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCH
AQLRNEAVTSYYVFDVLDIDGTSTSDLPYLERREALANLSLEHPRIKVPPHWLNVDGPTM
HHHHHHHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCEECCCCHHH
LEVARKHHLEGIVAKNISSIYQSGKRSRDWIKTPLRANCEAVVCGFLPGSGGAAGGVGSL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCE
ILGAHDDSRVLRYIGNVGTGLTDRQRRELRDKLVELHQPISPFTIEPPRAVTRNASWSRP
EEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCC
ILVCDVEYREYTGGSLRHPSFRGLRNDKTADEVNVPGRH
EEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]