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The map label for this gene is xerC [H]

Identifier: 77454660

GI number: 77454660

Start: 86985

End: 88268

Strand: Direct

Name: xerC [H]

Synonym: pREL1_0093

Alternate gene names: 77454660

Gene position: 86985-88268 (Clockwise)

Preceding gene: 77454658

Following gene: 77454661

Centisome position: 32.03

GC content: 60.98

Gene sequence:

>1284_bases
ATGTGCAGCGAGATGCGCCGGGCTGATCTTGCAGGGCTGGTCGTTCCCGACGTGGGGCGGCTGATTTCGACAGGTTCCGA
AGCAGAGCCCTACCGGTTACTCGATGCGTCGGGTGAGGTAATCGGCGCTGCGACACTATTTTTCGAGGAACTTCACGCGT
GTGACCGATCGTCGGCGACGATCCGATCGTACGGGCATGACTTGTTGCGGTGGTGGAGATTTCTCGCAGCGGTCGACGTG
GGATGGGAGAGAGCCAGTCCCGCGGAGGGCCGTGATTTTGCGCGTTGGATGAAGATTGCGGATAAACCCAGGCGTGAACA
TTGGCGGAGGCGGGGCGAAAAAGTCTCCGGCACAACACCTGTAGGGGGCAATGCGGCCAAGAGTGGTCATTGGGTGGTCA
ACGAGGTCACCGGCAAGCCGCGGCAGGGACAGAAATTCTCCCCGGCCACTCGAGCGCACGCGGAAACGGTGTTGCGGGCG
TTCTACGATTTTCAGATGAGCATCGGTGCTGGGCCGGTCGTCAATCCGTTCCCGGTGGATCGCTCGCCCCGCGCTTTTCG
GTCGAACGCGCATCACGATCCGCAGGATCCGTTTCGTAACGAGCGGAAGGGGCGATACAGACCCAAGGTTCCGAAACGGA
TACCCAAGCGCATTCCCGATGATCGTTTCAACGAACTATTCGCGGCGTTGTCGTCTAACCGAGATCGGGCAATGTTGGCC
TTCTGGGTTTCGACCGGCGCCCGCGCCGACGAGCTCCTGTCGATGTCCCAGAAGAGTGCGGACCCGGGCCAGCAATTGAT
CACCGTAATAAGGAAGGGGACCCGGGAGGTCCAACAGTTGCCGGCGTCGCCAGATGCATTCGTGTGGTTGCGGATCTATC
AAGAAGAGGCCTGGGGAAAGGATGCCCCTCACGGCTGCGATCATCCCTTGTGGATGACGTTGCGCAGGCCGTGGCGGCAG
CTGTCGTATTCGGGAGCGCGCGCGATGTTCTCACGGGCGCAGTCGATGTTGGGATCCAATTGGACCATTCACGACCTGCG
CCACACCGCAGCCTTTCGGATGACGAGCGATCCTGACATGCCGTTGTCCGATGTGCAATGGATCCTGGGCCACGCGCACC
TGACAACCACTCAGCTGTATCTGACCCCGAGCCGCGACGAAGTTTTCGCGCACGTACGAGCCCACCATGCTCGATACACC
GGCAACACCCAATCGCTGCACGCACCGCCAGCGCCGGGCTACAACCCGGCAGTGTTGGACGTACTTTTCGGAGGTCGACG
CTGA

Upstream 100 bases:

>100_bases
CCACTCTCGGGCAGCCCCCGACAGGGGAGCGCTGGCGTATTAACTGAACTAAAAAATTGCATCATTGCAGGTCAGGGGCT
GTGCTGATACTTTCCTCAGT

Downstream 100 bases:

>100_bases
TGGTTTCTGCACGTGTCTCCAAAGCGCCTGCCAGTTGGAGCCTGAACGTCGATGCCCGCGAAGGTGCGAATCGCAGTGTC
ATCGACACACTCCTCGATCG

Product: putative integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MCSEMRRADLAGLVVPDVGRLISTGSEAEPYRLLDASGEVIGAATLFFEELHACDRSSATIRSYGHDLLRWWRFLAAVDV
GWERASPAEGRDFARWMKIADKPRREHWRRRGEKVSGTTPVGGNAAKSGHWVVNEVTGKPRQGQKFSPATRAHAETVLRA
FYDFQMSIGAGPVVNPFPVDRSPRAFRSNAHHDPQDPFRNERKGRYRPKVPKRIPKRIPDDRFNELFAALSSNRDRAMLA
FWVSTGARADELLSMSQKSADPGQQLITVIRKGTREVQQLPASPDAFVWLRIYQEEAWGKDAPHGCDHPLWMTLRRPWRQ
LSYSGARAMFSRAQSMLGSNWTIHDLRHTAAFRMTSDPDMPLSDVQWILGHAHLTTTQLYLTPSRDEVFAHVRAHHARYT
GNTQSLHAPPAPGYNPAVLDVLFGGRR

Sequences:

>Translated_427_residues
MCSEMRRADLAGLVVPDVGRLISTGSEAEPYRLLDASGEVIGAATLFFEELHACDRSSATIRSYGHDLLRWWRFLAAVDV
GWERASPAEGRDFARWMKIADKPRREHWRRRGEKVSGTTPVGGNAAKSGHWVVNEVTGKPRQGQKFSPATRAHAETVLRA
FYDFQMSIGAGPVVNPFPVDRSPRAFRSNAHHDPQDPFRNERKGRYRPKVPKRIPKRIPDDRFNELFAALSSNRDRAMLA
FWVSTGARADELLSMSQKSADPGQQLITVIRKGTREVQQLPASPDAFVWLRIYQEEAWGKDAPHGCDHPLWMTLRRPWRQ
LSYSGARAMFSRAQSMLGSNWTIHDLRHTAAFRMTSDPDMPLSDVQWILGHAHLTTTQLYLTPSRDEVFAHVRAHHARYT
GNTQSLHAPPAPGYNPAVLDVLFGGRR
>Mature_427_residues
MCSEMRRADLAGLVVPDVGRLISTGSEAEPYRLLDASGEVIGAATLFFEELHACDRSSATIRSYGHDLLRWWRFLAAVDV
GWERASPAEGRDFARWMKIADKPRREHWRRRGEKVSGTTPVGGNAAKSGHWVVNEVTGKPRQGQKFSPATRAHAETVLRA
FYDFQMSIGAGPVVNPFPVDRSPRAFRSNAHHDPQDPFRNERKGRYRPKVPKRIPKRIPDDRFNELFAALSSNRDRAMLA
FWVSTGARADELLSMSQKSADPGQQLITVIRKGTREVQQLPASPDAFVWLRIYQEEAWGKDAPHGCDHPLWMTLRRPWRQ
LSYSGARAMFSRAQSMLGSNWTIHDLRHTAAFRMTSDPDMPLSDVQWILGHAHLTTTQLYLTPSRDEVFAHVRAHHARYT
GNTQSLHAPPAPGYNPAVLDVLFGGRR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=189, Percent_Identity=31.2169312169312, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789261, Length=206, Percent_Identity=26.6990291262136, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 48244; Mature: 48244

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSEMRRADLAGLVVPDVGRLISTGSEAEPYRLLDASGEVIGAATLFFEELHACDRSSAT
CCCHHHHHHHCCEECCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHH
IRSYGHDLLRWWRFLAAVDVGWERASPAEGRDFARWMKIADKPRREHWRRRGEKVSGTTP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
VGGNAAKSGHWVVNEVTGKPRQGQKFSPATRAHAETVLRAFYDFQMSIGAGPVVNPFPVD
CCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RSPRAFRSNAHHDPQDPFRNERKGRYRPKVPKRIPKRIPDDRFNELFAALSSNRDRAMLA
CCCHHHHCCCCCCCCCHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEE
FWVSTGARADELLSMSQKSADPGQQLITVIRKGTREVQQLPASPDAFVWLRIYQEEAWGK
EEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCC
DAPHGCDHPLWMTLRRPWRQLSYSGARAMFSRAQSMLGSNWTIHDLRHTAAFRMTSDPDM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCC
PLSDVQWILGHAHLTTTQLYLTPSRDEVFAHVRAHHARYTGNTQSLHAPPAPGYNPAVLD
CHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
VLFGGRR
HHCCCCC
>Mature Secondary Structure
MCSEMRRADLAGLVVPDVGRLISTGSEAEPYRLLDASGEVIGAATLFFEELHACDRSSAT
CCCHHHHHHHCCEECCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHH
IRSYGHDLLRWWRFLAAVDVGWERASPAEGRDFARWMKIADKPRREHWRRRGEKVSGTTP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
VGGNAAKSGHWVVNEVTGKPRQGQKFSPATRAHAETVLRAFYDFQMSIGAGPVVNPFPVD
CCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RSPRAFRSNAHHDPQDPFRNERKGRYRPKVPKRIPKRIPDDRFNELFAALSSNRDRAMLA
CCCHHHHCCCCCCCCCHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEE
FWVSTGARADELLSMSQKSADPGQQLITVIRKGTREVQQLPASPDAFVWLRIYQEEAWGK
EEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCC
DAPHGCDHPLWMTLRRPWRQLSYSGARAMFSRAQSMLGSNWTIHDLRHTAAFRMTSDPDM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCC
PLSDVQWILGHAHLTTTQLYLTPSRDEVFAHVRAHHARYTGNTQSLHAPPAPGYNPAVLD
CHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
VLFGGRR
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA