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The map label for this gene is ctaC [H]

Identifier: 75674422

GI number: 75674422

Start: 254299

End: 255156

Strand: Direct

Name: ctaC [H]

Synonym: Nwi_0223

Alternate gene names: 75674422

Gene position: 254299-255156 (Clockwise)

Preceding gene: 75674417

Following gene: 75674423

Centisome position: 7.47

GC content: 59.32

Gene sequence:

>858_bases
ATGAAGATGTCGATGGGCCAATATGGCCGCCGGTTTGGCCGCCGGTTTCTGGGATTGGCGTTTGGAGGAGCGGCTTTTGC
CGCAGGTGGCGCGGCATTTGCGGCGGATGAGATAGGTCAGCCGCATGCGTGGGGCTTTGATCTTCAGCAGGGCGTGACGC
CTGTGATGGAGAGCATTGCGCGGATGCATAACGGGCTTCTGGTGGTGATCACGCTGATCACGCTGTTTGTGACGGCCTTG
CTGGTTGTTGCGATGGTGCGGTTCAACGCGCGCTCCAATCCGGTTCCGTCGAAGACGACGCACAACACGATGATCGAGGT
TGCGTGGACGATCATCCCGGTTCTGATCCTGGTCGGCATTGCGGTTCCCTCATTCCGTCTTTTGTTTGAGCAGCTTGACC
TTCCGAAGGCTGACCTGACGGTGAAGGCGACCGGCAAGCAGTGGTACTGGACCTACACCTATCCGGACAACGGCAAGTTC
GAGTTTGACTCGCTGCTGGCGCAGGACAAGAAGCCGCGTCTGCTTGCGGTGGACAACGAGCTGGTTGTTCCGGTGAACAA
GGTGGTCCGGGTTCAGGTGATCGGGGCTGATGTCATTCATTCCTTTGGAGTTCCGTCGTTCGGCATGAAGGTGGACGCGA
TTCCGGGTCGTCTCAACGAGACCTGGTTCAAGGCCACGAAGACGGGCATTTTCTACGGCCAGTGCTCTGAGCTGTGCGGC
CGGGACCATGCCTTCATGCCGATTGCGGTTCGCGTGGTGAGCGAGCAGGAATTTGCGGCGTGGGTTGAAGTCGCGAAGAA
GAAGTTTGCCTCGAACCCGGCGAACGCGGTGGCGTCGGCTGCCGGCGTGATGCAATAG

Upstream 100 bases:

>100_bases
GGCTGTTCGCGGATGCGTTACATGAGCGGCAGGCTCGTCGTCGGCGGGAACTGCTTAGGGGGTTGTTTAGGGTGAATTTA
TGACAAGGAGCGCGAGCGGC

Downstream 100 bases:

>100_bases
GCGTCGCGTCGGGCGATTTCGACGACGAGGGGCGGCGCCTGCGAAGGGGTCGCCCGCCAGGGTTCGAAGGACTTCAAGGG
ACGAAAGACAGGATTAGACA

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKMSMGQYGRRFGRRFLGLAFGGAAFAAGGAAFAADEIGQPHAWGFDLQQGVTPVMESIARMHNGLLVVITLITLFVTAL
LVVAMVRFNARSNPVPSKTTHNTMIEVAWTIIPVLILVGIAVPSFRLLFEQLDLPKADLTVKATGKQWYWTYTYPDNGKF
EFDSLLAQDKKPRLLAVDNELVVPVNKVVRVQVIGADVIHSFGVPSFGMKVDAIPGRLNETWFKATKTGIFYGQCSELCG
RDHAFMPIAVRVVSEQEFAAWVEVAKKKFASNPANAVASAAGVMQ

Sequences:

>Translated_285_residues
MKMSMGQYGRRFGRRFLGLAFGGAAFAAGGAAFAADEIGQPHAWGFDLQQGVTPVMESIARMHNGLLVVITLITLFVTAL
LVVAMVRFNARSNPVPSKTTHNTMIEVAWTIIPVLILVGIAVPSFRLLFEQLDLPKADLTVKATGKQWYWTYTYPDNGKF
EFDSLLAQDKKPRLLAVDNELVVPVNKVVRVQVIGADVIHSFGVPSFGMKVDAIPGRLNETWFKATKTGIFYGQCSELCG
RDHAFMPIAVRVVSEQEFAAWVEVAKKKFASNPANAVASAAGVMQ
>Mature_285_residues
MKMSMGQYGRRFGRRFLGLAFGGAAFAAGGAAFAADEIGQPHAWGFDLQQGVTPVMESIARMHNGLLVVITLITLFVTAL
LVVAMVRFNARSNPVPSKTTHNTMIEVAWTIIPVLILVGIAVPSFRLLFEQLDLPKADLTVKATGKQWYWTYTYPDNGKF
EFDSLLAQDKKPRLLAVDNELVVPVNKVVRVQVIGADVIHSFGVPSFGMKVDAIPGRLNETWFKATKTGIFYGQCSELCG
RDHAFMPIAVRVVSEQEFAAWVEVAKKKFASNPANAVASAAGVMQ

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=222, Percent_Identity=39.1891891891892, Blast_Score=178, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6226540, Length=243, Percent_Identity=39.0946502057613, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31151; Mature: 31151

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMSMGQYGRRFGRRFLGLAFGGAAFAAGGAAFAADEIGQPHAWGFDLQQGVTPVMESIA
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCCCCCCHHHCCHHHHHHHH
RMHNGLLVVITLITLFVTALLVVAMVRFNARSNPVPSKTTHNTMIEVAWTIIPVLILVGI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AVPSFRLLFEQLDLPKADLTVKATGKQWYWTYTYPDNGKFEFDSLLAQDKKPRLLAVDNE
CCHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCCCCEEEECCC
LVVPVNKVVRVQVIGADVIHSFGVPSFGMKVDAIPGRLNETWFKATKTGIFYGQCSELCG
EEECCCCEEEEEEECHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHCCEEEECHHHHCC
RDHAFMPIAVRVVSEQEFAAWVEVAKKKFASNPANAVASAAGVMQ
CCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKMSMGQYGRRFGRRFLGLAFGGAAFAAGGAAFAADEIGQPHAWGFDLQQGVTPVMESIA
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCCCCCCHHHCCHHHHHHHH
RMHNGLLVVITLITLFVTALLVVAMVRFNARSNPVPSKTTHNTMIEVAWTIIPVLILVGI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AVPSFRLLFEQLDLPKADLTVKATGKQWYWTYTYPDNGKFEFDSLLAQDKKPRLLAVDNE
CCHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCCCCEEEECCC
LVVPVNKVVRVQVIGADVIHSFGVPSFGMKVDAIPGRLNETWFKATKTGIFYGQCSELCG
EEECCCCEEEEEEECHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHCCEEEECHHHHCC
RDHAFMPIAVRVVSEQEFAAWVEVAKKKFASNPANAVASAAGVMQ
CCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA