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The map label for this gene is yoeA [H]

Identifier: 75674361

GI number: 75674361

Start: 189383

End: 190732

Strand: Direct

Name: yoeA [H]

Synonym: Nwi_0162

Alternate gene names: 75674361

Gene position: 189383-190732 (Clockwise)

Preceding gene: 75674360

Following gene: 75674362

Centisome position: 5.57

GC content: 65.41

Gene sequence:

>1350_bases
ATGATGACCACGCAACCGCTGTGGCGGGCGTATGTCCTCTTCCTGATGCCGATGATGCTGAGCAACGTCCTCCAGTCGTT
GTTCGGAACCGTCAACGGCATCTATCTCGGCCAGATGATCGGCGTCGATGCGCTCGCCGCCGTCTCCATCTTCTTTCCGG
TGATGTTCTTCTTTCTCTCCTTCATCCTCGGACTCGGCGCGGGTTCGTCGATGCTGATCGGCCAGGCGTGGGGCGCGCGC
GAAGCCGGCAAGGCTAAGGCGATCGCGGGAACCACGCTCGCCCTGACGTTGCTCGGCGGCGGCGTCATTGCGGTCGGCGG
GGGACTGTTCGCGCGCGAACTGATGATGGCGCTGGCCGTGCCGTCCAACATTCTCGACGATGCGACGGACTACGCCCGCA
TCATGATGATCACCATGCCGGCGATCTTCACGTTCCTGCTCGCAACCGCGATGATGCGCGGCGTCGGCGACACGGTCACG
CCGTTATGGGCGCTTGCGATCTCGACAGCGATCGGGCTCGTCGTGACGCCGGCGCTCATCCGCGGATGGTTCGGCTTGCC
GCGGCTGGGCGTGGTCAGCGCGGCGATCGCGTCCGCGATCTCGGCGGTGGTGACGCTGCTGTGGCTCGGGCTGCACATGC
GGTGGATGAACCATCCGCTGGCGCCCGATAAGGTGCTGCTGCGCGCGATGCGGCTCGATCGCGAACTGCTCGGCAAGGTG
CTGCGTATCGGGATTCCGACCGCCGTCCAGCTCATGGCGATGTCACTCGCCGAGATCGTGCTGCTCGGCATCGTCAACGG
CTTCGGCTCCGACGCCACGGCCGCCTATGGCGCCGTCAACCAGGTGCTGGGCTACGCGCAATTCCCGGCGATCTCGATCG
CCATCACCGCGTCGATCTTCGCGGCGCAGGCGATCGGCGCGGGCGAGAGCGAACGGATCGGCGCGGTCGTGCGCACCGCG
ATGTGGCTCAACCTGTTGATGACCGGCGGTCTGGTCGTCCTTGGCTACCTGTTCTCACGGACCATCGTCGGGCTTTTCAT
CACCAGCCCGGAGGTGCTCGAACTGGCGCAGACGCTGCTGTACATCGTGCTCTGGAGCACGGTCCCGTTCGGCATGGCGT
GCGTATTCGCCGCCACCATGCGGGCGAGCGGAACGGTGATGGTGCCGACGCTGCTGTCGATTCTCGCGATCGTCGTGGTC
GAGGTGCCGGTCGCCATCGTGCTCAGCCGCCAGATCGGGGTCGAGGGCGTCTGGATCGCCTATCCGGCCGCGTTCTGCGC
GATGATGGCGTTGCAAATGGCCTTCTATCTGATGGTCTGGCGCAAGCAGGAGATCAGGCGGCTGATCTGA

Upstream 100 bases:

>100_bases
GCTTGTTCGGCGCGCCGGATCCGCGGACCCGCGGGTCAAGCGCCGCCGGATATTGAGGTGATGACCTGCGCGGGCGCTGA
GCCTCCACAAGGATTCGATC

Downstream 100 bases:

>100_bases
TGAAACAGCACAGGTCTTGCCTTGCGCAAGGATATCCACTTCGCCTGAAAATGCTCCGGACATAGACAAACAGGGAGCCC
ATCGATGCGCATTCTCGTCG

Product: multi anti extrusion protein MatE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MMTTQPLWRAYVLFLMPMMLSNVLQSLFGTVNGIYLGQMIGVDALAAVSIFFPVMFFFLSFILGLGAGSSMLIGQAWGAR
EAGKAKAIAGTTLALTLLGGGVIAVGGGLFARELMMALAVPSNILDDATDYARIMMITMPAIFTFLLATAMMRGVGDTVT
PLWALAISTAIGLVVTPALIRGWFGLPRLGVVSAAIASAISAVVTLLWLGLHMRWMNHPLAPDKVLLRAMRLDRELLGKV
LRIGIPTAVQLMAMSLAEIVLLGIVNGFGSDATAAYGAVNQVLGYAQFPAISIAITASIFAAQAIGAGESERIGAVVRTA
MWLNLLMTGGLVVLGYLFSRTIVGLFITSPEVLELAQTLLYIVLWSTVPFGMACVFAATMRASGTVMVPTLLSILAIVVV
EVPVAIVLSRQIGVEGVWIAYPAAFCAMMALQMAFYLMVWRKQEIRRLI

Sequences:

>Translated_449_residues
MMTTQPLWRAYVLFLMPMMLSNVLQSLFGTVNGIYLGQMIGVDALAAVSIFFPVMFFFLSFILGLGAGSSMLIGQAWGAR
EAGKAKAIAGTTLALTLLGGGVIAVGGGLFARELMMALAVPSNILDDATDYARIMMITMPAIFTFLLATAMMRGVGDTVT
PLWALAISTAIGLVVTPALIRGWFGLPRLGVVSAAIASAISAVVTLLWLGLHMRWMNHPLAPDKVLLRAMRLDRELLGKV
LRIGIPTAVQLMAMSLAEIVLLGIVNGFGSDATAAYGAVNQVLGYAQFPAISIAITASIFAAQAIGAGESERIGAVVRTA
MWLNLLMTGGLVVLGYLFSRTIVGLFITSPEVLELAQTLLYIVLWSTVPFGMACVFAATMRASGTVMVPTLLSILAIVVV
EVPVAIVLSRQIGVEGVWIAYPAAFCAMMALQMAFYLMVWRKQEIRRLI
>Mature_449_residues
MMTTQPLWRAYVLFLMPMMLSNVLQSLFGTVNGIYLGQMIGVDALAAVSIFFPVMFFFLSFILGLGAGSSMLIGQAWGAR
EAGKAKAIAGTTLALTLLGGGVIAVGGGLFARELMMALAVPSNILDDATDYARIMMITMPAIFTFLLATAMMRGVGDTVT
PLWALAISTAIGLVVTPALIRGWFGLPRLGVVSAAIASAISAVVTLLWLGLHMRWMNHPLAPDKVLLRAMRLDRELLGKV
LRIGIPTAVQLMAMSLAEIVLLGIVNGFGSDATAAYGAVNQVLGYAQFPAISIAITASIFAAQAIGAGESERIGAVVRTA
MWLNLLMTGGLVVLGYLFSRTIVGLFITSPEVLELAQTLLYIVLWSTVPFGMACVFAATMRASGTVMVPTLLSILAIVVV
EVPVAIVLSRQIGVEGVWIAYPAAFCAMMALQMAFYLMVWRKQEIRRLI

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=431, Percent_Identity=21.1136890951276, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47832; Mature: 47832

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTQPLWRAYVLFLMPMMLSNVLQSLFGTVNGIYLGQMIGVDALAAVSIFFPVMFFFLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILGLGAGSSMLIGQAWGAREAGKAKAIAGTTLALTLLGGGVIAVGGGLFARELMMALAV
HHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHC
PSNILDDATDYARIMMITMPAIFTFLLATAMMRGVGDTVTPLWALAISTAIGLVVTPALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGWFGLPRLGVVSAAIASAISAVVTLLWLGLHMRWMNHPLAPDKVLLRAMRLDRELLGKV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LRIGIPTAVQLMAMSLAEIVLLGIVNGFGSDATAAYGAVNQVLGYAQFPAISIAITASIF
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AAQAIGAGESERIGAVVRTAMWLNLLMTGGLVVLGYLFSRTIVGLFITSPEVLELAQTLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YIVLWSTVPFGMACVFAATMRASGTVMVPTLLSILAIVVVEVPVAIVLSRQIGVEGVWIA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHH
YPAAFCAMMALQMAFYLMVWRKQEIRRLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTTQPLWRAYVLFLMPMMLSNVLQSLFGTVNGIYLGQMIGVDALAAVSIFFPVMFFFLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILGLGAGSSMLIGQAWGAREAGKAKAIAGTTLALTLLGGGVIAVGGGLFARELMMALAV
HHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHC
PSNILDDATDYARIMMITMPAIFTFLLATAMMRGVGDTVTPLWALAISTAIGLVVTPALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGWFGLPRLGVVSAAIASAISAVVTLLWLGLHMRWMNHPLAPDKVLLRAMRLDRELLGKV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LRIGIPTAVQLMAMSLAEIVLLGIVNGFGSDATAAYGAVNQVLGYAQFPAISIAITASIF
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AAQAIGAGESERIGAVVRTAMWLNLLMTGGLVVLGYLFSRTIVGLFITSPEVLELAQTLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YIVLWSTVPFGMACVFAATMRASGTVMVPTLLSILAIVVVEVPVAIVLSRQIGVEGVWIA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHH
YPAAFCAMMALQMAFYLMVWRKQEIRRLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]