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The map label for this gene is hslV [H]

Identifier: 75674326

GI number: 75674326

Start: 147685

End: 148239

Strand: Direct

Name: hslV [H]

Synonym: Nwi_0127

Alternate gene names: 75674326

Gene position: 147685-148239 (Clockwise)

Preceding gene: 75674318

Following gene: 75674327

Centisome position: 4.34

GC content: 62.88

Gene sequence:

>555_bases
ATGCAAGCATCACAGCCGGAGACGTGGCACGGCACCACGATCCTGACCGTCCGCAAGGGCGGCAAAGTGGTCATTGGCGG
CGACGGCCAGGTCTCGATCGGACAGACGGTCATCAAGTCCAACGCGAAAAAGGTCAGGAAGCTCGGCAAAGGCGACGTCA
TCGGCGGCTTTGCCGGCGCCACCGCCGATGCGTTCACCCTGTTCGAGCGGCTGGAAAGCAAGCTTGAGCAATATCCTGGG
CAACTTACACGCGCCGCTGTCGAACTCGCCAAGGACTGGCGCACCGACCGCTATCTGCGGCGGCTGGAAGCGATGATGCT
TGTCGCCGACAAGGACGTATCGCTGGTGCTGACCGGGACCGGAGACGTTCTGGAGCCGGAATCCGGCGTGATGGCGATCG
GCTCGGGGGGCAACTACGCGCTCGCCGCCGCGCGAGCCCTGATCGACTCCGACAAGGACGCGGAAACGATCGTCCGCAGT
GCTCTCGATATCGCCGCCGATATCTGTGTTTATACCAATCGAAACCTGACGATCGAAGCGCTGGCCGCGAGCTGA

Upstream 100 bases:

>100_bases
ACCCGTGCATTACGACCGTGGCGACGAATCCACGAAATCAAGCGCCGATTGCAAGGCCGCGCCGCAATGCCTAAATCTGG
CGGATCATGAAGGGGTTCAG

Downstream 100 bases:

>100_bases
GCGATGGCTTACGGCTTTCGCCCGATGACCGCCGCCGACCTGCCGACGATCCGGCGCTGGCTCGACACGCCGCATGTCGC
GGAATGGTGGGGCGACCCGG

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MQASQPETWHGTTILTVRKGGKVVIGGDGQVSIGQTVIKSNAKKVRKLGKGDVIGGFAGATADAFTLFERLESKLEQYPG
QLTRAAVELAKDWRTDRYLRRLEAMMLVADKDVSLVLTGTGDVLEPESGVMAIGSGGNYALAAARALIDSDKDAETIVRS
ALDIAADICVYTNRNLTIEALAAS

Sequences:

>Translated_184_residues
MQASQPETWHGTTILTVRKGGKVVIGGDGQVSIGQTVIKSNAKKVRKLGKGDVIGGFAGATADAFTLFERLESKLEQYPG
QLTRAAVELAKDWRTDRYLRRLEAMMLVADKDVSLVLTGTGDVLEPESGVMAIGSGGNYALAAARALIDSDKDAETIVRS
ALDIAADICVYTNRNLTIEALAAS
>Mature_184_residues
MQASQPETWHGTTILTVRKGGKVVIGGDGQVSIGQTVIKSNAKKVRKLGKGDVIGGFAGATADAFTLFERLESKLEQYPG
QLTRAAVELAKDWRTDRYLRRLEAMMLVADKDVSLVLTGTGDVLEPESGVMAIGSGGNYALAAARALIDSDKDAETIVRS
ALDIAADICVYTNRNLTIEALAAS

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=172, Percent_Identity=61.046511627907, Blast_Score=211, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19527; Mature: 19527

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQASQPETWHGTTILTVRKGGKVVIGGDGQVSIGQTVIKSNAKKVRKLGKGDVIGGFAGA
CCCCCCCCCCCEEEEEEECCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCEECCCCCC
TADAFTLFERLESKLEQYPGQLTRAAVELAKDWRTDRYLRRLEAMMLVADKDVSLVLTGT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCEEEEEECC
GDVLEPESGVMAIGSGGNYALAAARALIDSDKDAETIVRSALDIAADICVYTNRNLTIEA
CCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEE
LAAS
EECC
>Mature Secondary Structure
MQASQPETWHGTTILTVRKGGKVVIGGDGQVSIGQTVIKSNAKKVRKLGKGDVIGGFAGA
CCCCCCCCCCCEEEEEEECCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCEECCCCCC
TADAFTLFERLESKLEQYPGQLTRAAVELAKDWRTDRYLRRLEAMMLVADKDVSLVLTGT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCEEEEEECC
GDVLEPESGVMAIGSGGNYALAAARALIDSDKDAETIVRSALDIAADICVYTNRNLTIEA
CCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEE
LAAS
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA