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The map label for this gene is ycbL [H]

Identifier: 75674312

GI number: 75674312

Start: 132223

End: 132897

Strand: Direct

Name: ycbL [H]

Synonym: Nwi_0113

Alternate gene names: 75674312

Gene position: 132223-132897 (Clockwise)

Preceding gene: 75674310

Following gene: 75674314

Centisome position: 3.89

GC content: 61.48

Gene sequence:

>675_bases
ATGACGAGGGAAGACCAGACCAGGGCCAAAGTCGGCGCCGCAATCATTCCGGTAACGCCGTTCCGGCAGAACTGCACGCT
GCTGTGGTGCGAGGCGACCAGGGACGGGGTGGTCATCGATCCCGGAGGCGATATTCCGCTGATCAGGGCAGCCATTAAGC
AGGCGGGCGTGACGGTCGGACGGATCTGGCTTACGCATGGCCATATTGATCATGTGGGGGGCGCCGCGGAGTTGCGCGAC
GCGTTGAAGGTTCCCATCATGGGGCCGCATGTCGCCGACAAGTTCCTGCTCGACCATGTCGTCGAAAGCGGACGGCACTA
CGGCATGACCGGCATGCGCGATTTTGTCCCCGACCGCTGGCTCGAGGACGGCGATCAGGTCGAGGTGGGTCAACTCGCGT
TCGACGTTCTTCATTGCCCCGGCCATTCGCCCGGAAGCGTGGTTTTCTTTAACGCCGATCTCCATTTTGCGCATGTCGGC
GACGTGTTGTTCAACGGTTCCGTCGGCCGCACCGACTTGCCCGGCGGCAGCCGCGCCGTCCTGATCAAATCGATAACGGA
CAAACTGTTGCCGCTTGGAGATGACGTCGCTTTCATCTGCGGACATGGACCGGGATCGACCATCGGCCACGAGCGCGTGA
GCAATCCGTTCCTGACCGGAAATGTATGTGACTGA

Upstream 100 bases:

>100_bases
GAACTTGGCCGTTTGCGCCGTGTTTTGAGCTTTTCGGAGGCTGAACCGGCGATGCCGCGAAATCGCTTGGCGATGCCCTA
AAAATCGGCATTGTGCGGGT

Downstream 100 bases:

>100_bases
GTATTTTGGAGCATCTTCCGCGAAGTGGATACCGGTCACGCGGTGCAGACTGCGAGTCGCTCCTGTTCTTCGCCGTGAGG
GATGGCGCCGGCACACCTTT

Product: beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTREDQTRAKVGAAIIPVTPFRQNCTLLWCEATRDGVVIDPGGDIPLIRAAIKQAGVTVGRIWLTHGHIDHVGGAAELRD
ALKVPIMGPHVADKFLLDHVVESGRHYGMTGMRDFVPDRWLEDGDQVEVGQLAFDVLHCPGHSPGSVVFFNADLHFAHVG
DVLFNGSVGRTDLPGGSRAVLIKSITDKLLPLGDDVAFICGHGPGSTIGHERVSNPFLTGNVCD

Sequences:

>Translated_224_residues
MTREDQTRAKVGAAIIPVTPFRQNCTLLWCEATRDGVVIDPGGDIPLIRAAIKQAGVTVGRIWLTHGHIDHVGGAAELRD
ALKVPIMGPHVADKFLLDHVVESGRHYGMTGMRDFVPDRWLEDGDQVEVGQLAFDVLHCPGHSPGSVVFFNADLHFAHVG
DVLFNGSVGRTDLPGGSRAVLIKSITDKLLPLGDDVAFICGHGPGSTIGHERVSNPFLTGNVCD
>Mature_223_residues
TREDQTRAKVGAAIIPVTPFRQNCTLLWCEATRDGVVIDPGGDIPLIRAAIKQAGVTVGRIWLTHGHIDHVGGAAELRDA
LKVPIMGPHVADKFLLDHVVESGRHYGMTGMRDFVPDRWLEDGDQVEVGQLAFDVLHCPGHSPGSVVFFNADLHFAHVGD
VLFNGSVGRTDLPGGSRAVLIKSITDKLLPLGDDVAFICGHGPGSTIGHERVSNPFLTGNVCD

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=226, Percent_Identity=28.7610619469027, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787158, Length=204, Percent_Identity=52.4509803921569, Blast_Score=225, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17538952, Length=204, Percent_Identity=28.921568627451, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 24022; Mature: 23890

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTREDQTRAKVGAAIIPVTPFRQNCTLLWCEATRDGVVIDPGGDIPLIRAAIKQAGVTVG
CCCCHHHHHHHCEEEEECCCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHCCCEEE
RIWLTHGHIDHVGGAAELRDALKVPIMGPHVADKFLLDHVVESGRHYGMTGMRDFVPDRW
EEEEECCCHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHH
LEDGDQVEVGQLAFDVLHCPGHSPGSVVFFNADLHFAHVGDVLFNGSVGRTDLPGGSRAV
CCCCCCEEHHHHEEEHHCCCCCCCCEEEEEECCEEEEEECCEEECCCCCCCCCCCCCCEE
LIKSITDKLLPLGDDVAFICGHGPGSTIGHERVSNPFLTGNVCD
EEEEHHHHHCCCCCCEEEEEECCCCCCCCHHHCCCCEEECCCCC
>Mature Secondary Structure 
TREDQTRAKVGAAIIPVTPFRQNCTLLWCEATRDGVVIDPGGDIPLIRAAIKQAGVTVG
CCCHHHHHHHCEEEEECCCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHCCCEEE
RIWLTHGHIDHVGGAAELRDALKVPIMGPHVADKFLLDHVVESGRHYGMTGMRDFVPDRW
EEEEECCCHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHH
LEDGDQVEVGQLAFDVLHCPGHSPGSVVFFNADLHFAHVGDVLFNGSVGRTDLPGGSRAV
CCCCCCEEHHHHEEEHHCCCCCCCCEEEEEECCEEEEEECCEEECCCCCCCCCCCCCCEE
LIKSITDKLLPLGDDVAFICGHGPGSTIGHERVSNPFLTGNVCD
EEEEHHHHHCCCCCCEEEEEECCCCCCCCHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]