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The map label for this gene is regA [H]

Identifier: 75674310

GI number: 75674310

Start: 130852

End: 131406

Strand: Direct

Name: regA [H]

Synonym: Nwi_0111

Alternate gene names: 75674310

Gene position: 130852-131406 (Clockwise)

Preceding gene: 75674309

Following gene: 75674312

Centisome position: 3.85

GC content: 64.68

Gene sequence:

>555_bases
GTGAACGCCACCCCCGACGTCTCCCCGCAAGCCGACCGCTCGCTGCTGATCGTCGAGGATGACAAACCGTTTCTGGAGCG
TCTGTCGCGCGCCATGGAAACGCGCGGCTTCAATGTGACCCCATGCGACAGTGTCTCTGATGGCCTTGCGCATATCGGAA
AGTCTGCGCCGGCTTTTGCCGTGGTCGATCTCCGGCTGGGCGACGGCAACGGCCTCGACGTCGTATCCGCGCTTAAACGC
GAGCGCCCCGATGCGAGGGCGATCGTGCTGACCGGTTACGGCAACATCGCGACCGCTGTGACGGCGGTGAAGCTGGGCGC
GATCGATTACCTGTCCAAGCCTGCCGATGCCGACGACGTGGTCGCGGCGCTGCTCGCCAGCGGCACGGCGAAGTCCGAGG
TCCCGCCGAATCCGATGTCGGCCGATCGCGTGCGCTGGGAACACATTCAGCGCATCTATGAGATGTGCAATCGCAATGTG
TCGGAAACAGCCCGGCGGCTCAACATGCACCGCCGCACGCTGCAACGCATTCTGGCGAAACGCGCGCCTCGCTGA

Upstream 100 bases:

>100_bases
CAGGATAGTTATCACGGACCGCGACCTTGGCAACAATTGCTTGCGGTGCGCGGTTCAGCGACCATATGATTTCATACCAA
ACCAAGCGCGAGGTATCCCT

Downstream 100 bases:

>100_bases
ATCGAGATTTGATCCAACGGAAGCGAGAAGGCCCCTGGGTGCGGTTCAACTGCGTTCAATCAAGCTGTGTTTCTTTCGAC
TGAGCAGGATCTTGTCCGAA

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNATPDVSPQADRSLLIVEDDKPFLERLSRAMETRGFNVTPCDSVSDGLAHIGKSAPAFAVVDLRLGDGNGLDVVSALKR
ERPDARAIVLTGYGNIATAVTAVKLGAIDYLSKPADADDVVAALLASGTAKSEVPPNPMSADRVRWEHIQRIYEMCNRNV
SETARRLNMHRRTLQRILAKRAPR

Sequences:

>Translated_184_residues
MNATPDVSPQADRSLLIVEDDKPFLERLSRAMETRGFNVTPCDSVSDGLAHIGKSAPAFAVVDLRLGDGNGLDVVSALKR
ERPDARAIVLTGYGNIATAVTAVKLGAIDYLSKPADADDVVAALLASGTAKSEVPPNPMSADRVRWEHIQRIYEMCNRNV
SETARRLNMHRRTLQRILAKRAPR
>Mature_184_residues
MNATPDVSPQADRSLLIVEDDKPFLERLSRAMETRGFNVTPCDSVSDGLAHIGKSAPAFAVVDLRLGDGNGLDVVSALKR
ERPDARAIVLTGYGNIATAVTAVKLGAIDYLSKPADADDVVAALLASGTAKSEVPPNPMSADRVRWEHIQRIYEMCNRNV
SETARRLNMHRRTLQRILAKRAPR

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=30, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788905, Length=110, Percent_Identity=29.0909090909091, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=29.6296296296296, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20045; Mature: 20045

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATPDVSPQADRSLLIVEDDKPFLERLSRAMETRGFNVTPCDSVSDGLAHIGKSAPAFA
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEE
VVDLRLGDGNGLDVVSALKRERPDARAIVLTGYGNIATAVTAVKLGAIDYLSKPADADDV
EEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHH
VAALLASGTAKSEVPPNPMSADRVRWEHIQRIYEMCNRNVSETARRLNMHRRTLQRILAK
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RAPR
CCCC
>Mature Secondary Structure
MNATPDVSPQADRSLLIVEDDKPFLERLSRAMETRGFNVTPCDSVSDGLAHIGKSAPAFA
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEE
VVDLRLGDGNGLDVVSALKRERPDARAIVLTGYGNIATAVTAVKLGAIDYLSKPADADDV
EEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHH
VAALLASGTAKSEVPPNPMSADRVRWEHIQRIYEMCNRNVSETARRLNMHRRTLQRILAK
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RAPR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1547494 [H]