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The map label for this gene is dnaQ [H]

Identifier: 75674304

GI number: 75674304

Start: 124822

End: 125541

Strand: Direct

Name: dnaQ [H]

Synonym: Nwi_0105

Alternate gene names: 75674304

Gene position: 124822-125541 (Clockwise)

Preceding gene: 75674303

Following gene: 75674306

Centisome position: 3.67

GC content: 60.0

Gene sequence:

>720_bases
ATGCGCGAAATCGTTCTCGATACCGAAACCACCGGCCTGGATCCGCTGCGAGGCGACCGCCTTGTTGAGATCGGCTGCGT
TGAGATGTTCAACCGCATGCCGACGGGACAGACGTTCCACCGCTACATCAATCCCGAACGTGACATGCCGCAGGAGGCAT
TCGCGGTCCATGGCCTGTCGAGCGATTTTCTCGCCGACAAACCGCTGTTTGCGCACGTCGTCGATGAGTTTCTGGAGTTT
ATCGGTGATGCGCCCTTGGTCATTCACAACGCATCGTTCGATATCAGCTTCATCAATGCCGAGCTTGATCGTCTTAAAAG
GCAAGCGATCGGCCGCGATCGGCTGGTGGATACGCTGTTGCTGGCGCGTCGGAAGCATCCCGGCGTCTCGAACCGGCTGG
ACGATCTGTGCTCGCGCTATGCCATCGACAACAGCCGTCGGACCAAGCACGGCGCATTGCTGGACGCCGAACTGCTGGCG
GAAGTCTATATCGATCTGATCGGCGCGCGCCAGTCGCAATTGATCCTGGTGGAAACTGCGCCCCGCCAGCGCGGCGGGTC
ATTGGAAATGCCAAGACGCCAGCGAACCGTGCCGCTGGCGTCACGCGTCACCGCGGCCGACCGCATCGCGCATCGGGAGT
TCATCGCTACACTCGGCGAGAAGGCGATTTGGATGGAATTCCTGGAACAGGACTCCGAAAAGACCAGAACCGGCCTGTAG

Upstream 100 bases:

>100_bases
TGACGGAATCAATGCGGACTCCAGCATTTTGATTTGACGTGTTTCTTCACGCGAACCGGATTCCACTTCGCTAGATAACG
CTGCAATCTCACGGAACTTC

Downstream 100 bases:

>100_bases
ACGGGATTATGATCAACTTGGCTGTTGTTGCGCCGCGGCCTGACGTTCCATGTTCTGTCGATACAGGCTTACGAAATCGA
TGGGGTCGAGCATCAATGGC

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MREIVLDTETTGLDPLRGDRLVEIGCVEMFNRMPTGQTFHRYINPERDMPQEAFAVHGLSSDFLADKPLFAHVVDEFLEF
IGDAPLVIHNASFDISFINAELDRLKRQAIGRDRLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYIDLIGARQSQLILVETAPRQRGGSLEMPRRQRTVPLASRVTAADRIAHREFIATLGEKAIWMEFLEQDSEKTRTGL

Sequences:

>Translated_239_residues
MREIVLDTETTGLDPLRGDRLVEIGCVEMFNRMPTGQTFHRYINPERDMPQEAFAVHGLSSDFLADKPLFAHVVDEFLEF
IGDAPLVIHNASFDISFINAELDRLKRQAIGRDRLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYIDLIGARQSQLILVETAPRQRGGSLEMPRRQRTVPLASRVTAADRIAHREFIATLGEKAIWMEFLEQDSEKTRTGL
>Mature_239_residues
MREIVLDTETTGLDPLRGDRLVEIGCVEMFNRMPTGQTFHRYINPERDMPQEAFAVHGLSSDFLADKPLFAHVVDEFLEF
IGDAPLVIHNASFDISFINAELDRLKRQAIGRDRLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYIDLIGARQSQLILVETAPRQRGGSLEMPRRQRTVPLASRVTAADRIAHREFIATLGEKAIWMEFLEQDSEKTRTGL

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=235, Percent_Identity=43.8297872340426, Blast_Score=191, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 27119; Mature: 27119

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVLDTETTGLDPLRGDRLVEIGCVEMFNRMPTGQTFHRYINPERDMPQEAFAVHGLS
CCCEEECCCCCCCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHCCC
SDFLADKPLFAHVVDEFLEFIGDAPLVIHNASFDISFINAELDRLKRQAIGRDRLVDTLL
CHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHCCHHHHHHHHH
LARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLAEVYIDLIGARQSQLILVETA
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
PRQRGGSLEMPRRQRTVPLASRVTAADRIAHREFIATLGEKAIWMEFLEQDSEKTRTGL
CCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MREIVLDTETTGLDPLRGDRLVEIGCVEMFNRMPTGQTFHRYINPERDMPQEAFAVHGLS
CCCEEECCCCCCCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHCCC
SDFLADKPLFAHVVDEFLEFIGDAPLVIHNASFDISFINAELDRLKRQAIGRDRLVDTLL
CHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHCCHHHHHHHHH
LARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLAEVYIDLIGARQSQLILVETA
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
PRQRGGSLEMPRRQRTVPLASRVTAADRIAHREFIATLGEKAIWMEFLEQDSEKTRTGL
CCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]