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The map label for this gene is ftsK [H]

Identifier: 75674282

GI number: 75674282

Start: 98638

End: 101139

Strand: Direct

Name: ftsK [H]

Synonym: Nwi_0083

Alternate gene names: 75674282

Gene position: 98638-101139 (Clockwise)

Preceding gene: 75674281

Following gene: 75674283

Centisome position: 2.9

GC content: 66.55

Gene sequence:

>2502_bases
ATGAGCATGGCAGCGATCGAACGTCTTCTTCCCATCGTCGATCAGATACCGCCGTCGATCCGCGAGCCGCTCGCCCGTCG
CCTGCGCGAACTGACCGGGCTCGGCCTGATCGGATTGTCGGGCGCGGCCGCAGCCGCGCTGATGACGTGGTCGGTGCAGG
ACCCGAGCCTGAGCCACGCCACCTCGCGCCCGATCCACAACGTCCTCGGCTATCCCGGCGCGATCGGCGCGGATCTTCTG
ATGCAGCTTCTCGGTCTCGGCGCGATCATGCTGATCCTGCCGGTGGCGATCTGGGGATGGCGGATGCTGACCCATCGCCC
GTTCGACCGCGAGGCTTCGCGTCTCGCCTGCTGGATTCTCTGCACCACATCCGCCGCCGGCTTCGCCAGTTGCTGGCCTC
ATAACGGCGCCTGGCCGCTGCCCACCGGTCTCGGTGGCGTGGTCGGCGACGCGCTGGTGCGGGCGCCCGCGATCCTGTTC
GGCCCGGCGGGCGTGCTGCAAAGCATCCTGCTCGGCGCGATCATGCTTCTGGTCATGGCGGCGACGTTCCTATGGGCCAG
CGGCATACGATCGCGGCCGGCCGAAGAATTGCCCGAAATCGAGGACGACGCGCCTTTCGATGAGGGCGACGACCACGCCT
CGGTCTCGCTGGGCTGGGCGGTTCACGCGCTGATGAGCGCGAAGGCGCGGCTCAAGCGCCTGAAGATCGGCGCGCTGCTT
GCGCTCGCCTACAAGTCGCTGGTGTCGAGCGCGCCACGGAATTCCGGTGCGCTGGCGTTCGAGCGTCAGGAGCCCGTTCT
CGGCGGCGGACCCGTCGCTCCCTCCCTGGCGCCGGGTCGCGCGGGCCATGACGACGACATCGATGACGAGCCTGACGACG
ATCCGGAGGACGAAGCGGAAGACGAGGAGGACAACGATGCGCCGCCGGTTGTCGCCGCGCCGCGCCGGAAGGCCGCTCCC
CGCCAGCCCGCGAAGAAGGCCGGCAAGTTCGAGCTGCCCTCTGTCAACGTTCTGAGCGCGCCGCGCGCCTCCGACCGCCA
GCCGCTCAGCAAGTCCGAGCTGGAAGCGAATTCCCGGGCGCTGGAAGGCGTGCTTGGCGACTTCGGCGTGCGCGGCGAGA
TCGTGAAAGCCAATCCCGGACCGGTGGTGACGCTGTATGAACTGGAGCCCGCGCCCGGCATCAAGTCGGCGCGCGTCATC
GGCCTCGCCGACGATATCGCCCGCTCGATGAGCGCGCTGTCCGCGCGCGTCGCCGTCGTTCCCGGCCGCAACGCCATCGG
CATCGAACTGCCGAACGCGCATCGCGAGAAGGTGTACCTGCGGGAGCTGCTCACTGCCAGGGAGGCGACCGAGTCGGTCG
CCAAGCTGCCGCTCTGCCTCGGCAAGACCATCGGCGGCGACCCCGTCATCATCGATCTCGCGCGCACCCCGCACATGCTG
ATCGCCGGCACCACCGGTTCCGGCAAATCGGTCGCGATCAACACCATGATTCTCAGCCTGCTGTACCGGCTGCGGCCCGA
TCAGTGCCGTCTCATCATGGTCGATCCGAAGATGCTCGAACTCTCGGTCTATGACGGCATCCCGCATCTGCTGACGCCGG
TCGTCACCGACCCGAAGAAGGCGGTGGTCGCGCTGAAATGGGCCGTGCGCGAGATGGAAGAGCGCTACAAGAAGATGGCC
AAGCTCGGCGTGCGCAACATCGACGGCTACAATACCCGTCTCGTCGACGCCAAGGCCAAGGGCGAGGAACTGACCCGCAC
GGTGCATACCGGCTTCGACAAGGAAACCGGCAAGGCGATCTACGAGGAAGAGAAGCTGGAATTCGAGCCGCTGCCCTTCA
TCGTCATCATCGTGGATGAAATGGCCGACCTGATGATGGTCGCTGGCAAGGATATCGAGGGCGCGGTCCAGCGACTTGCG
CAGATGGCGCGCGCCGCCGGCCTTCATGTTATTCTCGCGACCCAGCGCCCGTCGGTCGACGTCATCACCGGCACCATCAA
GGCCAACTTCCCGACCCGCATCGCCTTCCAGGTGACGTCGAAGATCGACAGCCGCACCATTCTCGGCGAAATGGGCGCCG
AGCAATTGCTCGGCCAGGGCGACATGCTCTACATGGCGGGCGGTGGTCGCATCTCGCGCGTGCACGGGCCGTTTGCGTCG
GATGAAGAAGTCGAGAAGGTGGTCCGCCACCTCAAGACGCAGGGCGCGCCCGAGTATCTCGAGGCGGTCACGGCTGAAGA
ACCCGCCGAGGGCGAGGATGGCGCGGTGTTCGACGGCACGAGCATGGGCAGCGACGGCGGCGGCGATCTGTTCGCGCAGG
CGGTCGCGATCGTGAAGCGCGACCGCAAGGCCTCGACCAGCTACATTCAGCGCCGTCTCCAGATCGGCTACAATCGCGCC
GCTTCGCTGATGGAGCGCATGGAACTCGAAGGCATCGTCGGGCAGGCCAATCACGCAGGAAAGCGCGAAATCCTGATCGA
GGAAGAAGAAGGCCAATTCTGA

Upstream 100 bases:

>100_bases
CGGCGCGGGCTATATCCGCCTGGCGCTGGTGGCGGACATCGAAACCACGGCCGAGGCGTTGCGTCGGCTGGTGAAAACAC
TCGGTTAGTCGCGGGGCACC

Downstream 100 bases:

>100_bases
TCATGACGATCACGATGATCAGGTTTTTCGGAGTCGCGAAATCGCCACAGCGCTGCGCGAGACCCATTCGACCGCGCGTC
GCGGATGTGAATGTTAGAAT

Product: cell division protein FtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 833; Mature: 832

Protein sequence:

>833_residues
MSMAAIERLLPIVDQIPPSIREPLARRLRELTGLGLIGLSGAAAAALMTWSVQDPSLSHATSRPIHNVLGYPGAIGADLL
MQLLGLGAIMLILPVAIWGWRMLTHRPFDREASRLACWILCTTSAAGFASCWPHNGAWPLPTGLGGVVGDALVRAPAILF
GPAGVLQSILLGAIMLLVMAATFLWASGIRSRPAEELPEIEDDAPFDEGDDHASVSLGWAVHALMSAKARLKRLKIGALL
ALAYKSLVSSAPRNSGALAFERQEPVLGGGPVAPSLAPGRAGHDDDIDDEPDDDPEDEAEDEEDNDAPPVVAAPRRKAAP
RQPAKKAGKFELPSVNVLSAPRASDRQPLSKSELEANSRALEGVLGDFGVRGEIVKANPGPVVTLYELEPAPGIKSARVI
GLADDIARSMSALSARVAVVPGRNAIGIELPNAHREKVYLRELLTAREATESVAKLPLCLGKTIGGDPVIIDLARTPHML
IAGTTGSGKSVAINTMILSLLYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWAVREMEERYKKMA
KLGVRNIDGYNTRLVDAKAKGEELTRTVHTGFDKETGKAIYEEEKLEFEPLPFIVIIVDEMADLMMVAGKDIEGAVQRLA
QMARAAGLHVILATQRPSVDVITGTIKANFPTRIAFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFAS
DEEVEKVVRHLKTQGAPEYLEAVTAEEPAEGEDGAVFDGTSMGSDGGGDLFAQAVAIVKRDRKASTSYIQRRLQIGYNRA
ASLMERMELEGIVGQANHAGKREILIEEEEGQF

Sequences:

>Translated_833_residues
MSMAAIERLLPIVDQIPPSIREPLARRLRELTGLGLIGLSGAAAAALMTWSVQDPSLSHATSRPIHNVLGYPGAIGADLL
MQLLGLGAIMLILPVAIWGWRMLTHRPFDREASRLACWILCTTSAAGFASCWPHNGAWPLPTGLGGVVGDALVRAPAILF
GPAGVLQSILLGAIMLLVMAATFLWASGIRSRPAEELPEIEDDAPFDEGDDHASVSLGWAVHALMSAKARLKRLKIGALL
ALAYKSLVSSAPRNSGALAFERQEPVLGGGPVAPSLAPGRAGHDDDIDDEPDDDPEDEAEDEEDNDAPPVVAAPRRKAAP
RQPAKKAGKFELPSVNVLSAPRASDRQPLSKSELEANSRALEGVLGDFGVRGEIVKANPGPVVTLYELEPAPGIKSARVI
GLADDIARSMSALSARVAVVPGRNAIGIELPNAHREKVYLRELLTAREATESVAKLPLCLGKTIGGDPVIIDLARTPHML
IAGTTGSGKSVAINTMILSLLYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWAVREMEERYKKMA
KLGVRNIDGYNTRLVDAKAKGEELTRTVHTGFDKETGKAIYEEEKLEFEPLPFIVIIVDEMADLMMVAGKDIEGAVQRLA
QMARAAGLHVILATQRPSVDVITGTIKANFPTRIAFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFAS
DEEVEKVVRHLKTQGAPEYLEAVTAEEPAEGEDGAVFDGTSMGSDGGGDLFAQAVAIVKRDRKASTSYIQRRLQIGYNRA
ASLMERMELEGIVGQANHAGKREILIEEEEGQF
>Mature_832_residues
SMAAIERLLPIVDQIPPSIREPLARRLRELTGLGLIGLSGAAAAALMTWSVQDPSLSHATSRPIHNVLGYPGAIGADLLM
QLLGLGAIMLILPVAIWGWRMLTHRPFDREASRLACWILCTTSAAGFASCWPHNGAWPLPTGLGGVVGDALVRAPAILFG
PAGVLQSILLGAIMLLVMAATFLWASGIRSRPAEELPEIEDDAPFDEGDDHASVSLGWAVHALMSAKARLKRLKIGALLA
LAYKSLVSSAPRNSGALAFERQEPVLGGGPVAPSLAPGRAGHDDDIDDEPDDDPEDEAEDEEDNDAPPVVAAPRRKAAPR
QPAKKAGKFELPSVNVLSAPRASDRQPLSKSELEANSRALEGVLGDFGVRGEIVKANPGPVVTLYELEPAPGIKSARVIG
LADDIARSMSALSARVAVVPGRNAIGIELPNAHREKVYLRELLTAREATESVAKLPLCLGKTIGGDPVIIDLARTPHMLI
AGTTGSGKSVAINTMILSLLYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWAVREMEERYKKMAK
LGVRNIDGYNTRLVDAKAKGEELTRTVHTGFDKETGKAIYEEEKLEFEPLPFIVIIVDEMADLMMVAGKDIEGAVQRLAQ
MARAAGLHVILATQRPSVDVITGTIKANFPTRIAFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFASD
EEVEKVVRHLKTQGAPEYLEAVTAEEPAEGEDGAVFDGTSMGSDGGGDLFAQAVAIVKRDRKASTSYIQRRLQIGYNRAA
SLMERMELEGIVGQANHAGKREILIEEEEGQF

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=496, Percent_Identity=51.008064516129, Blast_Score=484, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 89372; Mature: 89241

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMAAIERLLPIVDQIPPSIREPLARRLRELTGLGLIGLSGAAAAALMTWSVQDPSLSHA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCHHHHHHHEEECCCCCCCCHH
TSRPIHNVLGYPGAIGADLLMQLLGLGAIMLILPVAIWGWRMLTHRPFDREASRLACWIL
HCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEE
CTTSAAGFASCWPHNGAWPLPTGLGGVVGDALVRAPAILFGPAGVLQSILLGAIMLLVMA
EECCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHHHH
ATFLWASGIRSRPAEELPEIEDDAPFDEGDDHASVSLGWAVHALMSAKARLKRLKIGALL
HHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
ALAYKSLVSSAPRNSGALAFERQEPVLGGGPVAPSLAPGRAGHDDDIDDEPDDDPEDEAE
HHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEEDNDAPPVVAAPRRKAAPRQPAKKAGKFELPSVNVLSAPRASDRQPLSKSELEANSRA
CCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHH
LEGVLGDFGVRGEIVKANPGPVVTLYELEPAPGIKSARVIGLADDIARSMSALSARVAVV
HHHHHHCCCCCCEEEECCCCCEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHEEEEE
PGRNAIGIELPNAHREKVYLRELLTAREATESVAKLPLCLGKTIGGDPVIIDLARTPHML
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEE
IAGTTGSGKSVAINTMILSLLYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKK
EEECCCCCCEEHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEHHCCCHHHHCCCCCCCHH
AVVALKWAVREMEERYKKMAKLGVRNIDGYNTRLVDAKAKGEELTRTVHTGFDKETGKAI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCHHCCHH
YEEEKLEFEPLPFIVIIVDEMADLMMVAGKDIEGAVQRLAQMARAAGLHVILATQRPSVD
HHHCCCCCCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCE
VITGTIKANFPTRIAFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFAS
EEEEEEEECCCCEEEEEEHHCCCCHHHHHHHCHHHHHCCCCEEEEECCCEEEEECCCCCC
DEEVEKVVRHLKTQGAPEYLEAVTAEEPAEGEDGAVFDGTSMGSDGGGDLFAQAVAIVKR
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
DRKASTSYIQRRLQIGYNRAASLMERMELEGIVGQANHAGKREILIEEEEGQF
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SMAAIERLLPIVDQIPPSIREPLARRLRELTGLGLIGLSGAAAAALMTWSVQDPSLSHA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCHHHHHHHEEECCCCCCCCHH
TSRPIHNVLGYPGAIGADLLMQLLGLGAIMLILPVAIWGWRMLTHRPFDREASRLACWIL
HCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEE
CTTSAAGFASCWPHNGAWPLPTGLGGVVGDALVRAPAILFGPAGVLQSILLGAIMLLVMA
EECCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHHHH
ATFLWASGIRSRPAEELPEIEDDAPFDEGDDHASVSLGWAVHALMSAKARLKRLKIGALL
HHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
ALAYKSLVSSAPRNSGALAFERQEPVLGGGPVAPSLAPGRAGHDDDIDDEPDDDPEDEAE
HHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEEDNDAPPVVAAPRRKAAPRQPAKKAGKFELPSVNVLSAPRASDRQPLSKSELEANSRA
CCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHH
LEGVLGDFGVRGEIVKANPGPVVTLYELEPAPGIKSARVIGLADDIARSMSALSARVAVV
HHHHHHCCCCCCEEEECCCCCEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHEEEEE
PGRNAIGIELPNAHREKVYLRELLTAREATESVAKLPLCLGKTIGGDPVIIDLARTPHML
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEE
IAGTTGSGKSVAINTMILSLLYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKK
EEECCCCCCEEHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEHHCCCHHHHCCCCCCCHH
AVVALKWAVREMEERYKKMAKLGVRNIDGYNTRLVDAKAKGEELTRTVHTGFDKETGKAI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCHHCCHH
YEEEKLEFEPLPFIVIIVDEMADLMMVAGKDIEGAVQRLAQMARAAGLHVILATQRPSVD
HHHCCCCCCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCE
VITGTIKANFPTRIAFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFAS
EEEEEEEECCCCEEEEEEHHCCCCHHHHHHHCHHHHHCCCCEEEEECCCEEEEECCCCCC
DEEVEKVVRHLKTQGAPEYLEAVTAEEPAEGEDGAVFDGTSMGSDGGGDLFAQAVAIVKR
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
DRKASTSYIQRRLQIGYNRAASLMERMELEGIVGQANHAGKREILIEEEEGQF
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]