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The map label for this gene is visC [C]

Identifier: 75674278

GI number: 75674278

Start: 92582

End: 93802

Strand: Direct

Name: visC [C]

Synonym: Nwi_0079

Alternate gene names: 75674278

Gene position: 92582-93802 (Clockwise)

Preceding gene: 75674276

Following gene: 75674281

Centisome position: 2.72

GC content: 68.22

Gene sequence:

>1221_bases
ATGACGACACGACAGAGCATTGTCATCTGCGGCGGCGCATTTGCCGGTCTGGCGCTGGCGCTGGCGCTGCGCCAGGGGCT
CGGCAACGAAATTCCGATCGTGGTCGCCGATCCGATGCTGGCGAACCGGCCGAGCCGCGATCCGCGCGCCACCGCCATCG
TGGCGGCGTGCCGCCGCCTGTTCGAGGCGCTCGGGGTCTGGGACGAAGTGGCCGCGACCGCGCAGCCGATGCTTGACATG
GTGGTCACCGATTCGAAGCTTGAGGACGCCACCCGTCCGGTGTTCCTGACCTTCGCCGGCGACGTCCAGCCCGGCGAGCC
GTTCGCGCATATGGTGGAGAACCGCTATCTGATCGAGGCGCTGGCGTCGCGCGCGGAAACCGCGGGCGTTGACCTGCGCG
CCACGGCGGTGACGGGAAACGACGCGAAGCCCGGCGGCGTCACCGTCTCGCTGGCCGACGGCTCCACGATCGAGGCGAGC
CTTCTGGTCGCGGCCGACGGCGCACGCTCGAAGCTGCGCGAGCGCGCCGGGATCGCCACCCACGGCTGGGAATATGATCA
GTCCGGCATCGTCGTCACCGTCGGCCATGAGCGCGATCATCAGGGCCGCGCCGAAGAGCATTTTCTTCCCGCCGGGCCGT
TCGCGATCCTGCCGCTGACGGGCAGGCGCTCGTCGCTGGTGTGGACCGAGAAGCGGGCGGACGCCGCGCGCATCGTCGCG
CTTGCGGAAGAAGAATTTCACGCCGAGCTGGAGCAGCGCTTCGGCCTTCACCTCGGCGAGGTCAGGGCGCTCGACAAGCC
GCGCGCGTTTCCGCTTCAGTATTTCGTCGCGCGTTCATTCATCGCGGAGCGGCTGGCGCTGGTGGGCGACGCGGCGCATG
TGATCCATCCGATCGCGGGACAGGGTCTCAACCTCGGACTGAAGGATGTCGCGGCGCTTGCCGAGGTCGTGGTCGATGCC
GTCAGGCTCGGCATCGATCCGGGGCAGGCGGACGTGCTGGAGCGCTATCAGCGCTGGCGGCGCTTCGACACCATGGCGAT
GGGCTTGGCCACCAACACGCTTAACGTGCTGTTCTCCAACGAATCGACGCTGTTGCGCGGCGTGCGCGACATCGGGCTCG
GTCTGGTCGACCGAATGCCGCCTTTGAAGAACGCCTTCATTCGCCAGGCGGCCGGACTGACCGGCGAGGTGCCGCGGCTG
TTGAAGGGCGAGGTGTTGTAG

Upstream 100 bases:

>100_bases
GAAACGACGATACGGTCCAGGCGGTTGCTAAGGAAGCAACGTTTGGAAACCCGTTTAGCCCGACTATACTGTAGTGGCAC
AGGAGCAAGGCGTAGGTACC

Downstream 100 bases:

>100_bases
GGTGGTGAGAGCGGCGTACTTGAGCGATAAAGTCCTGTAAGCGCTTGGTCTTTATGGTTTTCGAGAGTCGCGTCTAACAT
CTTGGAATCACAATCGATTC

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTTRQSIVICGGAFAGLALALALRQGLGNEIPIVVADPMLANRPSRDPRATAIVAACRRLFEALGVWDEVAATAQPMLDM
VVTDSKLEDATRPVFLTFAGDVQPGEPFAHMVENRYLIEALASRAETAGVDLRATAVTGNDAKPGGVTVSLADGSTIEAS
LLVAADGARSKLRERAGIATHGWEYDQSGIVVTVGHERDHQGRAEEHFLPAGPFAILPLTGRRSSLVWTEKRADAARIVA
LAEEEFHAELEQRFGLHLGEVRALDKPRAFPLQYFVARSFIAERLALVGDAAHVIHPIAGQGLNLGLKDVAALAEVVVDA
VRLGIDPGQADVLERYQRWRRFDTMAMGLATNTLNVLFSNESTLLRGVRDIGLGLVDRMPPLKNAFIRQAAGLTGEVPRL
LKGEVL

Sequences:

>Translated_406_residues
MTTRQSIVICGGAFAGLALALALRQGLGNEIPIVVADPMLANRPSRDPRATAIVAACRRLFEALGVWDEVAATAQPMLDM
VVTDSKLEDATRPVFLTFAGDVQPGEPFAHMVENRYLIEALASRAETAGVDLRATAVTGNDAKPGGVTVSLADGSTIEAS
LLVAADGARSKLRERAGIATHGWEYDQSGIVVTVGHERDHQGRAEEHFLPAGPFAILPLTGRRSSLVWTEKRADAARIVA
LAEEEFHAELEQRFGLHLGEVRALDKPRAFPLQYFVARSFIAERLALVGDAAHVIHPIAGQGLNLGLKDVAALAEVVVDA
VRLGIDPGQADVLERYQRWRRFDTMAMGLATNTLNVLFSNESTLLRGVRDIGLGLVDRMPPLKNAFIRQAAGLTGEVPRL
LKGEVL
>Mature_405_residues
TTRQSIVICGGAFAGLALALALRQGLGNEIPIVVADPMLANRPSRDPRATAIVAACRRLFEALGVWDEVAATAQPMLDMV
VTDSKLEDATRPVFLTFAGDVQPGEPFAHMVENRYLIEALASRAETAGVDLRATAVTGNDAKPGGVTVSLADGSTIEASL
LVAADGARSKLRERAGIATHGWEYDQSGIVVTVGHERDHQGRAEEHFLPAGPFAILPLTGRRSSLVWTEKRADAARIVAL
AEEEFHAELEQRFGLHLGEVRALDKPRAFPLQYFVARSFIAERLALVGDAAHVIHPIAGQGLNLGLKDVAALAEVVVDAV
RLGIDPGQADVLERYQRWRRFDTMAMGLATNTLNVLFSNESTLLRGVRDIGLGLVDRMPPLKNAFIRQAAGLTGEVPRLL
KGEVL

Specific function: Not Yet Known. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=385, Percent_Identity=29.8701298701299, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI32967307, Length=345, Percent_Identity=31.5942028985507, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1789273, Length=403, Percent_Identity=35.7320099255583, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789274, Length=392, Percent_Identity=32.9081632653061, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786883, Length=407, Percent_Identity=35.6265356265356, Blast_Score=174, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25146631, Length=430, Percent_Identity=29.3023255813954, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321694, Length=294, Percent_Identity=28.9115646258503, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI19920760, Length=384, Percent_Identity=30.46875, Blast_Score=158, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43663; Mature: 43531

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRQSIVICGGAFAGLALALALRQGLGNEIPIVVADPMLANRPSRDPRATAIVAACRRL
CCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCHHCCCCCCCHHHHHHHHHHHHH
FEALGVWDEVAATAQPMLDMVVTDSKLEDATRPVFLTFAGDVQPGEPFAHMVENRYLIEA
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
LASRAETAGVDLRATAVTGNDAKPGGVTVSLADGSTIEASLLVAADGARSKLRERAGIAT
HHHHHHHCCCEEEEEEEECCCCCCCCEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCC
HGWEYDQSGIVVTVGHERDHQGRAEEHFLPAGPFAILPLTGRRSSLVWTEKRADAARIVA
CCCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCEEEEEECCCCCCEEEECCCCCHHHHHH
LAEEEFHAELEQRFGLHLGEVRALDKPRAFPLQYFVARSFIAERLALVGDAAHVIHPIAG
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
QGLNLGLKDVAALAEVVVDAVRLGIDPGQADVLERYQRWRRFDTMAMGLATNTLNVLFSN
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECC
ESTLLRGVRDIGLGLVDRMPPLKNAFIRQAAGLTGEVPRLLKGEVL
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHCCCCC
>Mature Secondary Structure 
TTRQSIVICGGAFAGLALALALRQGLGNEIPIVVADPMLANRPSRDPRATAIVAACRRL
CCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCHHCCCCCCCHHHHHHHHHHHHH
FEALGVWDEVAATAQPMLDMVVTDSKLEDATRPVFLTFAGDVQPGEPFAHMVENRYLIEA
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
LASRAETAGVDLRATAVTGNDAKPGGVTVSLADGSTIEASLLVAADGARSKLRERAGIAT
HHHHHHHCCCEEEEEEEECCCCCCCCEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCC
HGWEYDQSGIVVTVGHERDHQGRAEEHFLPAGPFAILPLTGRRSSLVWTEKRADAARIVA
CCCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCEEEEEECCCCCCEEEECCCCCHHHHHH
LAEEEFHAELEQRFGLHLGEVRALDKPRAFPLQYFVARSFIAERLALVGDAAHVIHPIAG
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
QGLNLGLKDVAALAEVVVDAVRLGIDPGQADVLERYQRWRRFDTMAMGLATNTLNVLFSN
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECC
ESTLLRGVRDIGLGLVDRMPPLKNAFIRQAAGLTGEVPRLLKGEVL
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]