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The map label for this gene is fur [C]

Identifier: 75674234

GI number: 75674234

Start: 39551

End: 40057

Strand: Direct

Name: fur [C]

Synonym: Nwi_0035

Alternate gene names: 75674234

Gene position: 39551-40057 (Clockwise)

Preceding gene: 75674230

Following gene: 75674236

Centisome position: 1.16

GC content: 60.75

Gene sequence:

>507_bases
ATGCCTGGCGTGAGTACAAGCGAGAACATCGTGGTTGTGACCGAAGAGGATCGTGATATCGCGGCGATCGGTCACGGACG
GCAGCCGACTTTGACGGGCTGCCCCTGGCACGACGTCAACGAAATGCTGCAATCGGTCGGGCTGCGGCCGACGCGGCAGC
GCATGGCGCTGGGCTGGCTGCTGTTCGGCAAGGGCGCGCGCCACCTCACGGCGGAAATGCTTTACGAAGAAGCGACCCTC
GCCAAGGTTCCCGTCTCGCTGGCCACCGTCTACAATACGCTCAATCAACTGACCGACGCCGGATTGTTGCGCCAGGTCAG
CGTTGACGGCACCAAGACCTATTTCGATACCAACGTCACCGCCCACCACCACTTCTACCTCGAAAACAATCACGAGCTGG
TCGACATTCCCGATCCGCATCTGGTGTTGCAGAAGATGCCGAACGTGCCGGAAGGTTACGAGATCAGCCGCATCGACATG
GTCGTGCGCCTGCGCAAGAAGCGCTGA

Upstream 100 bases:

>100_bases
TTCTAGTTGCGAAAAACTTGCATCTGAACGCCTTTGTTCCTATAGTTTGAGATAGTTGGTCCCTATAGGGACTGTTGACG
GCTGGATAAGAGCTTTTCGA

Downstream 100 bases:

>100_bases
ACCGCCGCACGGCCTCGATCGCGTTCGCATTGCCCGGCCCTGCGCCGGGCATTTGTTTTTTGTGAGAGGTGTGTTTGTGC
GAGAGGCGCCTGGGGCGTTT

Product: ferric-uptake regulator

Products: NA

Alternate protein names: Ferric Uptake Regulator Fur Family; Transcriptional Regulator Fur Family; FUR Family Transcriptional Regulator; Ferric-Uptake Regulator; Fe2+/Zn2+ Uptake Regulation Protein; Iron Response Regulator; Ferric Uptake Regulator; Fur Family Ferric Uptake Regulator; Fur Family Transcriptional Regulator; Ferric Uptake Regulator FUR Family; Transcriptional Regulator Fur Family Protein; Ferric Uptake Regulation Protein; Peroxide Stress Regulator; Iron Response Regulator Irr; Transcription Regulator; Transcriptional Regulator; Iron Transcriptional Regulator Protein; Ferric Uptake Transcriptional Regulator

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MPGVSTSENIVVVTEEDRDIAAIGHGRQPTLTGCPWHDVNEMLQSVGLRPTRQRMALGWLLFGKGARHLTAEMLYEEATL
AKVPVSLATVYNTLNQLTDAGLLRQVSVDGTKTYFDTNVTAHHHFYLENNHELVDIPDPHLVLQKMPNVPEGYEISRIDM
VVRLRKKR

Sequences:

>Translated_168_residues
MPGVSTSENIVVVTEEDRDIAAIGHGRQPTLTGCPWHDVNEMLQSVGLRPTRQRMALGWLLFGKGARHLTAEMLYEEATL
AKVPVSLATVYNTLNQLTDAGLLRQVSVDGTKTYFDTNVTAHHHFYLENNHELVDIPDPHLVLQKMPNVPEGYEISRIDM
VVRLRKKR
>Mature_167_residues
PGVSTSENIVVVTEEDRDIAAIGHGRQPTLTGCPWHDVNEMLQSVGLRPTRQRMALGWLLFGKGARHLTAEMLYEEATLA
KVPVSLATVYNTLNQLTDAGLLRQVSVDGTKTYFDTNVTAHHHFYLENNHELVDIPDPHLVLQKMPNVPEGYEISRIDMV
VRLRKKR

Specific function: Acts As A Global Negative Controlling Element, Employing Fe(2+) As A Cofactor To Bind The Operator Of The Repressed Genes. Regulates The Expression Of Several Outer-Membrane Proteins Including The Iron Transport Operon. [C]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 18925; Mature: 18794

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGVSTSENIVVVTEEDRDIAAIGHGRQPTLTGCPWHDVNEMLQSVGLRPTRQRMALGWL
CCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHE
LFGKGARHLTAEMLYEEATLAKVPVSLATVYNTLNQLTDAGLLRQVSVDGTKTYFDTNVT
EECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCE
AHHHFYLENNHELVDIPDPHLVLQKMPNVPEGYEISRIDMVVRLRKKR
EEEEEEECCCCEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGVSTSENIVVVTEEDRDIAAIGHGRQPTLTGCPWHDVNEMLQSVGLRPTRQRMALGWL
CCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHE
LFGKGARHLTAEMLYEEATLAKVPVSLATVYNTLNQLTDAGLLRQVSVDGTKTYFDTNVT
EECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCE
AHHHFYLENNHELVDIPDPHLVLQKMPNVPEGYEISRIDMVVRLRKKR
EEEEEEECCCCEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA