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The map label for this gene is mltA [H]

Identifier: 73542702

GI number: 73542702

Start: 3321218

End: 3322399

Strand: Reverse

Name: mltA [H]

Synonym: Reut_A3018

Alternate gene names: 73542702

Gene position: 3322399-3321218 (Counterclockwise)

Preceding gene: 73542704

Following gene: 73542698

Centisome position: 87.28

GC content: 69.88

Gene sequence:

>1182_bases
ATGCATGCGCGGCGGCGCTGGACAATACGAACAGACAAGATGGCAATTCCGCATTCCCTTTCCACGTTTTCGCGATCCCA
TAGCCGCACCGGCGCGCCCTGGCGCGGGTGGCTGGCGCTGGCTGCCGGCGCCGCGCTGCTGGCCGGCTGCATGAGCGGGC
CGCCGCCGCGCATCGAGACCGGCGGTGCGCCCGGCACGACGGCGCCAACGCCGGGTGCGCAGAAGGGGCGCCTGCAGGCC
GCGAACTGGAACGAGATCAGCGGCTGGACGCAGGACGACATGCGCGCCGCGTGGCCCGCGCTGCAGGCTAGCTGCCAGGC
GCTGAAGAAGCGCGCCGAATGGGGCCGCGCCTGTGCCGCTGGCCTGATGGTCGACGCCGGCGACCTCGGCGCCATGCGTG
CCTACTTTGAATCCAACTTCCAGCCCTACCGCGTCATCAACGGCGACGGCACCGACAACGGGCTGATCACCGGCTACTAC
GAACCGATCCTGCACGGCTCGCGCACACGGCAGGGCCAGTATCAGGTTCCGCTGTACCGCAAGCCGCCGCAACTGGCCAA
CCGCGCGCTGCCGCCGCGCGCCGAACTGCTGCAGAGCCCGGCGATGCGTGGCAACGAGGTGGTATGGGTCGACGATGCCG
TCGAGGCCGCCTTCCTGCAGATCCAGGGTTCGGGCCGTATCCGGCTCGCCAACGGCACCATGATGCGCGTGGGCTTTGGC
GGCACCAATGACCAGCCGTTCCGCTCGTTCGGCAAGTGGCTGCTCGACCGCGGCGAGATCACGCCGGCGCAGGCGACCAT
GCAGGGCATCAAGGCGTGGGCACGCGCCAACCCGTCGCGCGTCGAGGAAATGCTCAACGTGAACCCGCGCTTCGTGTTCT
TCAAGGAGCTGCCGCCGACCAATGACGGCCCGGTCGGTGCGCTCGGCGTGCCGCTCACGGCGGAGCGCTCGATCGCGGTC
GATCCGGCCACGATTCCGCTCGGTGTGCCTGTGTTCCTGTCGACCACGCGGCCGCTGTCGACCGAACCGATCGAGCGCCT
GATGTTCGCGCAGGACACCGGCAGCGCCATCAAGGGCGGTGTGCGTGCGGACTTCTTCTGGGGCGCGGGCGATGCCGCGG
GCGAGACGGCCGGCCGCATGAAGCAGGGCGGCCGGATGTGGGTGCTGATGCCGCGCAGCTGA

Upstream 100 bases:

>100_bases
GGCTTCAAGGAACTCGGACATGATCGGTATGGCGGGCGTCCTTCACAGGCGCCGGCAACGGTGAAGACTGACGCCGGGCA
TTGTAGGGCATCGCCCCCCG

Downstream 100 bases:

>100_bases
CGCGCCGCGCGGTAACTATCAGCGTGGGCGCTGGTCGACGATGCGCCGCGCCTTGCCGACCGAGCGCTCGATGCCGCCGG
TCGGCAGCACCTCGATGCCG

Product: MltA

Products: Muramic Acid Residue [C]

Alternate protein names: Mlt38; Murein hydrolase A [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MHARRRWTIRTDKMAIPHSLSTFSRSHSRTGAPWRGWLALAAGAALLAGCMSGPPPRIETGGAPGTTAPTPGAQKGRLQA
ANWNEISGWTQDDMRAAWPALQASCQALKKRAEWGRACAAGLMVDAGDLGAMRAYFESNFQPYRVINGDGTDNGLITGYY
EPILHGSRTRQGQYQVPLYRKPPQLANRALPPRAELLQSPAMRGNEVVWVDDAVEAAFLQIQGSGRIRLANGTMMRVGFG
GTNDQPFRSFGKWLLDRGEITPAQATMQGIKAWARANPSRVEEMLNVNPRFVFFKELPPTNDGPVGALGVPLTAERSIAV
DPATIPLGVPVFLSTTRPLSTEPIERLMFAQDTGSAIKGGVRADFFWGAGDAAGETAGRMKQGGRMWVLMPRS

Sequences:

>Translated_393_residues
MHARRRWTIRTDKMAIPHSLSTFSRSHSRTGAPWRGWLALAAGAALLAGCMSGPPPRIETGGAPGTTAPTPGAQKGRLQA
ANWNEISGWTQDDMRAAWPALQASCQALKKRAEWGRACAAGLMVDAGDLGAMRAYFESNFQPYRVINGDGTDNGLITGYY
EPILHGSRTRQGQYQVPLYRKPPQLANRALPPRAELLQSPAMRGNEVVWVDDAVEAAFLQIQGSGRIRLANGTMMRVGFG
GTNDQPFRSFGKWLLDRGEITPAQATMQGIKAWARANPSRVEEMLNVNPRFVFFKELPPTNDGPVGALGVPLTAERSIAV
DPATIPLGVPVFLSTTRPLSTEPIERLMFAQDTGSAIKGGVRADFFWGAGDAAGETAGRMKQGGRMWVLMPRS
>Mature_393_residues
MHARRRWTIRTDKMAIPHSLSTFSRSHSRTGAPWRGWLALAAGAALLAGCMSGPPPRIETGGAPGTTAPTPGAQKGRLQA
ANWNEISGWTQDDMRAAWPALQASCQALKKRAEWGRACAAGLMVDAGDLGAMRAYFESNFQPYRVINGDGTDNGLITGYY
EPILHGSRTRQGQYQVPLYRKPPQLANRALPPRAELLQSPAMRGNEVVWVDDAVEAAFLQIQGSGRIRLANGTMMRVGFG
GTNDQPFRSFGKWLLDRGEITPAQATMQGIKAWARANPSRVEEMLNVNPRFVFFKELPPTNDGPVGALGVPLTAERSIAV
DPATIPLGVPVFLSTTRPLSTEPIERLMFAQDTGSAIKGGVRADFFWGAGDAAGETAGRMKQGGRMWVLMPRS

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=370, Percent_Identity=31.3513513513514, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 42596; Mature: 42596

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHARRRWTIRTDKMAIPHSLSTFSRSHSRTGAPWRGWLALAAGAALLAGCMSGPPPRIET
CCCCEEEEEEECCEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
GGAPGTTAPTPGAQKGRLQAANWNEISGWTQDDMRAAWPALQASCQALKKRAEWGRACAA
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMVDAGDLGAMRAYFESNFQPYRVINGDGTDNGLITGYYEPILHGSRTRQGQYQVPLYR
CEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHHHHCCCCCCCCCEECCCCC
KPPQLANRALPPRAELLQSPAMRGNEVVWVDDAVEAAFLQIQGSGRIRLANGTMMRVGFG
CCHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCCEEEEEEEECCCEEEEECCEEEEEECC
GTNDQPFRSFGKWLLDRGEITPAQATMQGIKAWARANPSRVEEMLNVNPRFVFFKELPPT
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCC
NDGPVGALGVPLTAERSIAVDPATIPLGVPVFLSTTRPLSTEPIERLMFAQDTGSAIKGG
CCCCCCEECCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHCCC
VRADFFWGAGDAAGETAGRMKQGGRMWVLMPRS
CEEEEEECCCCCCCHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MHARRRWTIRTDKMAIPHSLSTFSRSHSRTGAPWRGWLALAAGAALLAGCMSGPPPRIET
CCCCEEEEEEECCEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
GGAPGTTAPTPGAQKGRLQAANWNEISGWTQDDMRAAWPALQASCQALKKRAEWGRACAA
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMVDAGDLGAMRAYFESNFQPYRVINGDGTDNGLITGYYEPILHGSRTRQGQYQVPLYR
CEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHHHHCCCCCCCCCEECCCCC
KPPQLANRALPPRAELLQSPAMRGNEVVWVDDAVEAAFLQIQGSGRIRLANGTMMRVGFG
CCHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCCEEEEEEEECCCEEEEECCEEEEEECC
GTNDQPFRSFGKWLLDRGEITPAQATMQGIKAWARANPSRVEEMLNVNPRFVFFKELPPT
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCC
NDGPVGALGVPLTAERSIAVDPATIPLGVPVFLSTTRPLSTEPIERLMFAQDTGSAIKGG
CCCCCCEECCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHCCC
VRADFFWGAGDAAGETAGRMKQGGRMWVLMPRS
CEEEEEECCCCCCCHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]