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The map label for this gene is dppC [H]

Identifier: 73542688

GI number: 73542688

Start: 3300333

End: 3301247

Strand: Reverse

Name: dppC [H]

Synonym: Reut_A3004

Alternate gene names: 73542688

Gene position: 3301247-3300333 (Counterclockwise)

Preceding gene: 73542689

Following gene: 73542687

Centisome position: 86.73

GC content: 64.48

Gene sequence:

>915_bases
ATGACTGCCGTAACCGCAGACAAACCGAAAGCCGCGCACGAGCAGACGCCGTTCCGCCGCTTCGCTGCCGAATTCCTCTC
CAGCAAGATTGCCGTGGCCGGGCTGATCACGCTGATCACAGTGATCCTGATCGCGATCTTCGCGCCATGGTTGGCGCCGC
AGAATCCGTATGACCTTGCCACGCTCGACGTGCTCGACGCACGCCTCGCGCCCGGCGAGCAGGCCGGCAACGGCATGACG
TTCGTGCTGGGCTCCGACGAGCAGGGGCGCGACATTCTGTCCGCGGTCATGTACGGGCTGCGCATCAGCATAGGCGTAGG
TGTGGTCAGCACGGTCATCGCGCTGATACTGGGCGCGACGCTGGGCCTGTTGGCTGGCTTCCTCGGCGGACGTACCGAAG
CGTTCATCATGCGCGTCGCCGACCTGCAGCTCTCGTTCCCGCCAATCCTGCTCGCGCTGATCCTGCTGGCCTTTCTGCGG
CCGGGCATCGGCAACATCGTGATCGCGCTCGTGGCGGTGCAATGGGCCTACTATGCGCGCACCACGCGCAGCGCAGCACT
CGTAGAACGCCGCAAGGAATACATCGAAGCCGCGACATGCCTCGGCCTGCCGCCGGGCCGCATCATGTTCCGACATCTGC
TGCCAAACTGCCTGCCGCCGCTGATCGTGATCGCGGCGCTGCAGGTGGCATCGGCCATCACGCTCGAAGCGACGCTGTCA
TTCCTCGGGCTCGGCGTGCCGATCACCGAGCCGTCGCTCGGTTCGCTGATTTCCAATGGCCAGCAGTACATGCTGTCCGG
CAAGTACTGGATCAGCTTCTTCCCGGGCATTGCGCTCGTCATCACCATCGTGGCCATGAATCTGGTGGCCGACCAGTTGC
GCGACGTGCTGAACCCGCGCCTGCAGACGCAATAG

Upstream 100 bases:

>100_bases
GGTGATCGTGACGCTGTTCATCCTGATCAATCTGGCGGTGGACATCCTCTACAGCGTGCTCGATCCGCGCGTGCGCATTG
CCGACAACAAGGGCTGAGCC

Downstream 100 bases:

>100_bases
GGAGGGGAGGGCAACATGGCACAACCTACCCTGGTGGTGGAACACCTCAAGACGCAGTTCTTCACGCGCGGCGGCATCGC
CAAAGCGGTCGACGACGTGT

Product: binding-protein dependent transport system inner membrane protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTAVTADKPKAAHEQTPFRRFAAEFLSSKIAVAGLITLITVILIAIFAPWLAPQNPYDLATLDVLDARLAPGEQAGNGMT
FVLGSDEQGRDILSAVMYGLRISIGVGVVSTVIALILGATLGLLAGFLGGRTEAFIMRVADLQLSFPPILLALILLAFLR
PGIGNIVIALVAVQWAYYARTTRSAALVERRKEYIEAATCLGLPPGRIMFRHLLPNCLPPLIVIAALQVASAITLEATLS
FLGLGVPITEPSLGSLISNGQQYMLSGKYWISFFPGIALVITIVAMNLVADQLRDVLNPRLQTQ

Sequences:

>Translated_304_residues
MTAVTADKPKAAHEQTPFRRFAAEFLSSKIAVAGLITLITVILIAIFAPWLAPQNPYDLATLDVLDARLAPGEQAGNGMT
FVLGSDEQGRDILSAVMYGLRISIGVGVVSTVIALILGATLGLLAGFLGGRTEAFIMRVADLQLSFPPILLALILLAFLR
PGIGNIVIALVAVQWAYYARTTRSAALVERRKEYIEAATCLGLPPGRIMFRHLLPNCLPPLIVIAALQVASAITLEATLS
FLGLGVPITEPSLGSLISNGQQYMLSGKYWISFFPGIALVITIVAMNLVADQLRDVLNPRLQTQ
>Mature_303_residues
TAVTADKPKAAHEQTPFRRFAAEFLSSKIAVAGLITLITVILIAIFAPWLAPQNPYDLATLDVLDARLAPGEQAGNGMTF
VLGSDEQGRDILSAVMYGLRISIGVGVVSTVIALILGATLGLLAGFLGGRTEAFIMRVADLQLSFPPILLALILLAFLRP
GIGNIVIALVAVQWAYYARTTRSAALVERRKEYIEAATCLGLPPGRIMFRHLLPNCLPPLIVIAALQVASAITLEATLSF
LGLGVPITEPSLGSLISNGQQYMLSGKYWISFFPGIALVITIVAMNLVADQLRDVLNPRLQTQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=304, Percent_Identity=43.421052631579, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787760, Length=290, Percent_Identity=37.9310344827586, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1787054, Length=293, Percent_Identity=32.7645051194539, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1789889, Length=249, Percent_Identity=36.144578313253, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787498, Length=277, Percent_Identity=37.1841155234657, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=28.4403669724771, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787549, Length=293, Percent_Identity=28.3276450511945, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32518; Mature: 32387

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVTADKPKAAHEQTPFRRFAAEFLSSKIAVAGLITLITVILIAIFAPWLAPQNPYDLA
CCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
TLDVLDARLAPGEQAGNGMTFVLGSDEQGRDILSAVMYGLRISIGVGVVSTVIALILGAT
HHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLLAGFLGGRTEAFIMRVADLQLSFPPILLALILLAFLRPGIGNIVIALVAVQWAYYAR
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TTRSAALVERRKEYIEAATCLGLPPGRIMFRHLLPNCLPPLIVIAALQVASAITLEATLS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLGVPITEPSLGSLISNGQQYMLSGKYWISFFPGIALVITIVAMNLVADQLRDVLNPR
HHHCCCCCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LQTQ
CCCC
>Mature Secondary Structure 
TAVTADKPKAAHEQTPFRRFAAEFLSSKIAVAGLITLITVILIAIFAPWLAPQNPYDLA
CCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
TLDVLDARLAPGEQAGNGMTFVLGSDEQGRDILSAVMYGLRISIGVGVVSTVIALILGAT
HHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLLAGFLGGRTEAFIMRVADLQLSFPPILLALILLAFLRPGIGNIVIALVAVQWAYYAR
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TTRSAALVERRKEYIEAATCLGLPPGRIMFRHLLPNCLPPLIVIAALQVASAITLEATLS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLGVPITEPSLGSLISNGQQYMLSGKYWISFFPGIALVITIVAMNLVADQLRDVLNPR
HHHCCCCCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LQTQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]