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The map label for this gene is tehA [H]

Identifier: 73542292

GI number: 73542292

Start: 2858586

End: 2859575

Strand: Direct

Name: tehA [H]

Synonym: Reut_A2607

Alternate gene names: 73542292

Gene position: 2858586-2859575 (Clockwise)

Preceding gene: 73542288

Following gene: 73542293

Centisome position: 75.1

GC content: 65.76

Gene sequence:

>990_bases
ATGACTATTGCAGCCAATCCCGCCGCCGCGGCGCCTACCCAGCGCAGTTCGGTCCAGCATCTCCCGGTCAACCTGTTCGG
CGCCGTCATGGGCCTCTCAGGGCTCTCGCTGGCATGGCGCGCCGCGAGCAATGTGTTCGGGACCAGCCCCGCCATTGCCG
ATGCCGTCGGCGTGGTGGCGGTCCTCACGTTCCTTGCACTGGCGGCGGGCTACCTCGCCAAGTGGCGCCTGTACCCGGCA
GCCGTCAAGGCCGAGTTCAACCATCCGATTGCAGGCAATTTCTTTGGCACCATCACCATTGCCATCCTGCTGCTGTCGTC
CGTCGTCGGCGTCTACAGCGAAGCGCTGGGTCAGGTGGTGTGGACCATCGGCGCCGCCCTGACCATTGCCCTGACCTATG
TGATTGCCAGCCGCCTCTTCCTCGGCAAGGGCGACCCGACGCACGTGACGCCTGCGTGGCTCATTCCGGGTGTGGCAACG
CTCGATATCGCCGTGGCCGGGGGCACCATGCCGATGGCCTGGGCGCCGGAGCTCAACCTGTTCGCCGTCGCTGTCGGCAC
GGTGATGGCGCTGGTGTTCTTCACGATGATCTTTGCCCGCCTGGTCCACCACGATCCACTGCCCGCCGGCATGGTGCCTT
CGCTGATCATCCTGATCGCGCCTTTCGAAGTCGGCTTCCTGGCCTATGTCAACGTGACCCAGCACGTCGACATGTTCGCC
GCCCTGCTGTTCTACTTCGGCCTGTTCCTGTTCGTGGTGCTCGCGGCCAAGGTGTTCCGGCGCTCGGTGCCGTTCGCCGC
GTCGTGGTGGGCCATCAGCTTCCCGATGGCTGCGCTGTCCAATGCCGCGCTGAAGTATGCGCACCATGCGGAGACCGGCG
TGCTGCGCATCGTCGCCGCGGTCATCCTTGCGCTGCTGACCGTCGCCATCGCCGTCCTGTTCGTCCGCACGCTGTATCGG
CTGTCCACGCACCGCCTGCTGGTCGGTTGA

Upstream 100 bases:

>100_bases
GCATTCCACGACAGCCCCATAGCAGGGACGAAACGCAGTCCGGGTTGTTCCATCGCCGACGCAACGCGCTCGGCACTCGA
TACAGGCAGACGAAAGCACG

Downstream 100 bases:

>100_bases
CGGCGCCCTTCCTCTCAACGCAACGCCTTTACCACGATGTCCTGGATCTTGCTGGCCTGTGCCGGCCTGCTGGAAGTTGC
TTTCGCCTTTGGCATGAAGT

Product: C4-dicarboxylate transporter/malic acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTIAANPAAAAPTQRSSVQHLPVNLFGAVMGLSGLSLAWRAASNVFGTSPAIADAVGVVAVLTFLALAAGYLAKWRLYPA
AVKAEFNHPIAGNFFGTITIAILLLSSVVGVYSEALGQVVWTIGAALTIALTYVIASRLFLGKGDPTHVTPAWLIPGVAT
LDIAVAGGTMPMAWAPELNLFAVAVGTVMALVFFTMIFARLVHHDPLPAGMVPSLIILIAPFEVGFLAYVNVTQHVDMFA
ALLFYFGLFLFVVLAAKVFRRSVPFAASWWAISFPMAALSNAALKYAHHAETGVLRIVAAVILALLTVAIAVLFVRTLYR
LSTHRLLVG

Sequences:

>Translated_329_residues
MTIAANPAAAAPTQRSSVQHLPVNLFGAVMGLSGLSLAWRAASNVFGTSPAIADAVGVVAVLTFLALAAGYLAKWRLYPA
AVKAEFNHPIAGNFFGTITIAILLLSSVVGVYSEALGQVVWTIGAALTIALTYVIASRLFLGKGDPTHVTPAWLIPGVAT
LDIAVAGGTMPMAWAPELNLFAVAVGTVMALVFFTMIFARLVHHDPLPAGMVPSLIILIAPFEVGFLAYVNVTQHVDMFA
ALLFYFGLFLFVVLAAKVFRRSVPFAASWWAISFPMAALSNAALKYAHHAETGVLRIVAAVILALLTVAIAVLFVRTLYR
LSTHRLLVG
>Mature_328_residues
TIAANPAAAAPTQRSSVQHLPVNLFGAVMGLSGLSLAWRAASNVFGTSPAIADAVGVVAVLTFLALAAGYLAKWRLYPAA
VKAEFNHPIAGNFFGTITIAILLLSSVVGVYSEALGQVVWTIGAALTIALTYVIASRLFLGKGDPTHVTPAWLIPGVATL
DIAVAGGTMPMAWAPELNLFAVAVGTVMALVFFTMIFARLVHHDPLPAGMVPSLIILIAPFEVGFLAYVNVTQHVDMFAA
LLFYFGLFLFVVLAAKVFRRSVPFAASWWAISFPMAALSNAALKYAHHAETGVLRIVAAVILALLTVAIAVLFVRTLYRL
STHRLLVG

Specific function: Responsible for potassium tellurite resistance when present in high copy number, probably by increasing the reduction rate of tellurite to metallic tellurium within the bacterium. Otherwise, phenotypically silent [H]

COG id: COG1275

COG function: function code P; Tellurite resistance protein and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family [H]

Homologues:

Organism=Escherichia coli, GI1787699, Length=318, Percent_Identity=27.0440251572327, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004695
- InterPro:   IPR011552 [H]

Pfam domain/function: PF03595 C4dic_mal_tran [H]

EC number: NA

Molecular weight: Translated: 34796; Mature: 34665

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAANPAAAAPTQRSSVQHLPVNLFGAVMGLSGLSLAWRAASNVFGTSPAIADAVGVVA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
VLTFLALAAGYLAKWRLYPAAVKAEFNHPIAGNFFGTITIAILLLSSVVGVYSEALGQVV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTIGAALTIALTYVIASRLFLGKGDPTHVTPAWLIPGVATLDIAVAGGTMPMAWAPELNL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHEEEEEECCCCCCCCCCCCHH
FAVAVGTVMALVFFTMIFARLVHHDPLPAGMVPSLIILIAPFEVGFLAYVNVTQHVDMFA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ALLFYFGLFLFVVLAAKVFRRSVPFAASWWAISFPMAALSNAALKYAHHAETGVLRIVAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILALLTVAIAVLFVRTLYRLSTHRLLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIAANPAAAAPTQRSSVQHLPVNLFGAVMGLSGLSLAWRAASNVFGTSPAIADAVGVVA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
VLTFLALAAGYLAKWRLYPAAVKAEFNHPIAGNFFGTITIAILLLSSVVGVYSEALGQVV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTIGAALTIALTYVIASRLFLGKGDPTHVTPAWLIPGVATLDIAVAGGTMPMAWAPELNL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHEEEEEECCCCCCCCCCCCHH
FAVAVGTVMALVFFTMIFARLVHHDPLPAGMVPSLIILIAPFEVGFLAYVNVTQHVDMFA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ALLFYFGLFLFVVLAAKVFRRSVPFAASWWAISFPMAALSNAALKYAHHAETGVLRIVAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILALLTVAIAVLFVRTLYRLSTHRLLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2060788; 9097039; 9278503; 8169225 [H]