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The map label for this gene is ytfL [H]

Identifier: 73542276

GI number: 73542276

Start: 2842070

End: 2843401

Strand: Direct

Name: ytfL [H]

Synonym: Reut_A2591

Alternate gene names: 73542276

Gene position: 2842070-2843401 (Clockwise)

Preceding gene: 73542275

Following gene: 73542281

Centisome position: 74.66

GC content: 61.86

Gene sequence:

>1332_bases
ATGTTCGTACTGACCCTGCTCCTCCTGATCCTGATCAGCGCCTTCTTCTCGATTTCCGAGATCGCGCTGACCGCCGCCCG
CCGCACCAAGCTGCAGGTTCTGTCCGAACGCGGCGACCGCCGTGCCACCAAGGTGCTGCTGCTGAAGGAAGAGCCCGGCA
ACTTCTTCACGATCGTGCAGATCGGCGTGAACAGCGTGGCGATCCTGGCCGGTATCCTCGGGGAAAAGCATGTCTCCGAT
CTGGTGTTCGGAGCGTTATCGCAGTACATGGATACCGGCATCGCGCAGCGCATCGCCAATATCGGCTCGTTCCTGATCGT
CACGCTGCTTTTTATCCAGTTTGCCGATCTGATCCCCAAGCGCATCGCGATGACGTTCCCCGAGGCCTGCGCGCTCGCGG
TGATCGATCCGATCCTGACGCTGCTGCGCGTGCTCAAGCCACTGGTCTACGTGTTCAATGCCGCCGCCGATGCCACGCTG
CGGCTGTTCGGCCTGCCGACCAAGACCGTCGAGCAGATCACCACCGAAGACATCGCCGCGATGGTCGATGCCGGCGCGGA
GGCCGGCGTGCTGCTCAAGCATGAAATCCACCTGATCGAGAATGTGTTCGAACTCGATTCAAAGAGCGTCACGGCGATCA
TGACGCCGCGCGATGACGTGGTCTACCTGAGCCTGGACGAGGGCGCCGACAGCGTGCGGCGCAAGCTCGTCAACCAGCCG
CATGCGCAATATCCGGTTTGCGGCCACGATCTCGACGACGTGCAGGGCTACATCGACTCCAAGGACATCCTGCAGTTGCT
GCTGGCCGACGAAACGGCAACGGTGATCGGCAATATCGGCAAGCACCACGACAAGAACGTGCTGGTGATTCCGGACACCC
TGACGCTTTCCGAAGCGCTCACACGCTTTCGCGAAATGCACGAGAACTTTGCCGTGGTGATGAACGAGTACGGCCTGGTA
GTCGGCATCGTCACGCTGGACGACATTGTCGGCGCGCTGATGGGCGACATCCTTTACTCGAGCGAGGATGAACAGATCGT
GCGGCGCGACGATAGCTCCTGGCTGGTGGACGGCCTGACACCGCTGATCGACCTGAAGAAGGCGCTGGAGATCGACGCGC
TGCCGGGCGAGGACTACGTCGATACGGTGGCAGGCCTGGTGATCTACGCGCTCAAGCGCATCCCGAAGAAATCGGAGTCG
ATCACCGTGGGAGGCTTCCGCTTCGAAGTGCTGGACATCGACCATCACAAGATCGATCAGCTCCTGGTGTCGCGCCTGAC
GGCCGGGACGACGGCGACGCTGGGACAGCCGGCGCCCGAAGCGGGTCGCTGA

Upstream 100 bases:

>100_bases
GACGCCACCGCCACTACTGCCACCAGAGGACGGGATTGATTGACAGCCTCGCGCGGCCTGCACCATCATCAAGGCGCCCG
AACGGTGCCCTCAACCAGCC

Downstream 100 bases:

>100_bases
GCGCGCCCGCCTGGCGATACTGCTCGAGCCTGTCGGGCAGGCGATACGCTACGAGATAGCCCGCTGCCACGATGACCGCG
GTCGCCGCCACAGCGCCGAG

Product: CBS:protein of unknown function DUF21:transporter-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MFVLTLLLLILISAFFSISEIALTAARRTKLQVLSERGDRRATKVLLLKEEPGNFFTIVQIGVNSVAILAGILGEKHVSD
LVFGALSQYMDTGIAQRIANIGSFLIVTLLFIQFADLIPKRIAMTFPEACALAVIDPILTLLRVLKPLVYVFNAAADATL
RLFGLPTKTVEQITTEDIAAMVDAGAEAGVLLKHEIHLIENVFELDSKSVTAIMTPRDDVVYLSLDEGADSVRRKLVNQP
HAQYPVCGHDLDDVQGYIDSKDILQLLLADETATVIGNIGKHHDKNVLVIPDTLTLSEALTRFREMHENFAVVMNEYGLV
VGIVTLDDIVGALMGDILYSSEDEQIVRRDDSSWLVDGLTPLIDLKKALEIDALPGEDYVDTVAGLVIYALKRIPKKSES
ITVGGFRFEVLDIDHHKIDQLLVSRLTAGTTATLGQPAPEAGR

Sequences:

>Translated_443_residues
MFVLTLLLLILISAFFSISEIALTAARRTKLQVLSERGDRRATKVLLLKEEPGNFFTIVQIGVNSVAILAGILGEKHVSD
LVFGALSQYMDTGIAQRIANIGSFLIVTLLFIQFADLIPKRIAMTFPEACALAVIDPILTLLRVLKPLVYVFNAAADATL
RLFGLPTKTVEQITTEDIAAMVDAGAEAGVLLKHEIHLIENVFELDSKSVTAIMTPRDDVVYLSLDEGADSVRRKLVNQP
HAQYPVCGHDLDDVQGYIDSKDILQLLLADETATVIGNIGKHHDKNVLVIPDTLTLSEALTRFREMHENFAVVMNEYGLV
VGIVTLDDIVGALMGDILYSSEDEQIVRRDDSSWLVDGLTPLIDLKKALEIDALPGEDYVDTVAGLVIYALKRIPKKSES
ITVGGFRFEVLDIDHHKIDQLLVSRLTAGTTATLGQPAPEAGR
>Mature_443_residues
MFVLTLLLLILISAFFSISEIALTAARRTKLQVLSERGDRRATKVLLLKEEPGNFFTIVQIGVNSVAILAGILGEKHVSD
LVFGALSQYMDTGIAQRIANIGSFLIVTLLFIQFADLIPKRIAMTFPEACALAVIDPILTLLRVLKPLVYVFNAAADATL
RLFGLPTKTVEQITTEDIAAMVDAGAEAGVLLKHEIHLIENVFELDSKSVTAIMTPRDDVVYLSLDEGADSVRRKLVNQP
HAQYPVCGHDLDDVQGYIDSKDILQLLLADETATVIGNIGKHHDKNVLVIPDTLTLSEALTRFREMHENFAVVMNEYGLV
VGIVTLDDIVGALMGDILYSSEDEQIVRRDDSSWLVDGLTPLIDLKKALEIDALPGEDYVDTVAGLVIYALKRIPKKSES
ITVGGFRFEVLDIDHHKIDQLLVSRLTAGTTATLGQPAPEAGR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=392, Percent_Identity=25.2551020408163, Blast_Score=145, Evalue=7e-35,
Organism=Escherichia coli, GI1790664, Length=439, Percent_Identity=46.6970387243736, Blast_Score=420, Evalue=1e-118,
Organism=Escherichia coli, GI145693175, Length=417, Percent_Identity=26.378896882494, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788119, Length=264, Percent_Identity=31.4393939393939, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082033, Length=298, Percent_Identity=29.1946308724832, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786879, Length=232, Percent_Identity=26.2931034482759, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48463; Mature: 48463

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVLTLLLLILISAFFSISEIALTAARRTKLQVLSERGDRRATKVLLLKEEPGNFFTIVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEE
IGVNSVAILAGILGEKHVSDLVFGALSQYMDTGIAQRIANIGSFLIVTLLFIQFADLIPK
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAMTFPEACALAVIDPILTLLRVLKPLVYVFNAAADATLRLFGLPTKTVEQITTEDIAA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
MVDAGAEAGVLLKHEIHLIENVFELDSKSVTAIMTPRDDVVYLSLDEGADSVRRKLVNQP
HHHCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHCCC
HAQYPVCGHDLDDVQGYIDSKDILQLLLADETATVIGNIGKHHDKNVLVIPDTLTLSEAL
CCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEECCCHHHHHHH
TRFREMHENFAVVMNEYGLVVGIVTLDDIVGALMGDILYSSEDEQIVRRDDSSWLVDGLT
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHH
PLIDLKKALEIDALPGEDYVDTVAGLVIYALKRIPKKSESITVGGFRFEVLDIDHHKIDQ
HHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCHHHHHH
LLVSRLTAGTTATLGQPAPEAGR
HHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFVLTLLLLILISAFFSISEIALTAARRTKLQVLSERGDRRATKVLLLKEEPGNFFTIVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEE
IGVNSVAILAGILGEKHVSDLVFGALSQYMDTGIAQRIANIGSFLIVTLLFIQFADLIPK
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAMTFPEACALAVIDPILTLLRVLKPLVYVFNAAADATLRLFGLPTKTVEQITTEDIAA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
MVDAGAEAGVLLKHEIHLIENVFELDSKSVTAIMTPRDDVVYLSLDEGADSVRRKLVNQP
HHHCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHCCC
HAQYPVCGHDLDDVQGYIDSKDILQLLLADETATVIGNIGKHHDKNVLVIPDTLTLSEAL
CCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEECCCHHHHHHH
TRFREMHENFAVVMNEYGLVVGIVTLDDIVGALMGDILYSSEDEQIVRRDDSSWLVDGLT
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHH
PLIDLKKALEIDALPGEDYVDTVAGLVIYALKRIPKKSESITVGGFRFEVLDIDHHKIDQ
HHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCHHHHHH
LLVSRLTAGTTATLGQPAPEAGR
HHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]