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The map label for this gene is mltB [H]

Identifier: 73542241

GI number: 73542241

Start: 2800473

End: 2801579

Strand: Direct

Name: mltB [H]

Synonym: Reut_A2556

Alternate gene names: 73542241

Gene position: 2800473-2801579 (Clockwise)

Preceding gene: 73542232

Following gene: 73542242

Centisome position: 73.57

GC content: 66.31

Gene sequence:

>1107_bases
ATGACCGACACCCAGCGTTCATTGCGCCGCCCGTTGCTGGGCGCTGCGTTATCCGCTGCCGCACTGGGACTCTGCGGCCT
CTCCCCAAGCCTCCTCGCCGCCGGCAAGCGCCGCGTGAGCGTGCGGGAAGAAGAAATCGAGCCCGGGCGCTATCGCGACA
ATGCACAGACCCGCGCCTTTATCGAAGACATGGTGACTCGCCACGGCTTCGACCGCGGCACGCTGGAAGGCTGGTTCGGG
CAGGCGGTCTATTCCGCCACCGTGGTGCGGCTGGTCATGCCGCCAACCACGCCAGGGCGCAAAAGCTGGCGTGCCTACCG
TTCGCGCTTTATCGAACCGATCCGCATCAACGCGGGCATGCGCTTCTGGCAGGAAAACCGCGACACGCTGCGGCGCGCCG
AAGCCGAGTTCGGCGTGCCGGCTTCGGTCATCGTCGGCATCATCGGCGTGGAAACCATCTACGGGCGCGACATGGGCACG
TTCCGCGTCATCGACTCGCTCTCGACGCTGGCTTTCGACTATCCGTCCACGCCTAACCGCGACGCCCGGGCGACGCTGTT
CCGCAACCAGCTGGCGGATTACCTGATCTGGTGCCGCGACACGCGTACCGACGTCTTTTCGGTGCTGGGCTCCTTTGCCG
GTGCGATCGGCATCCCGCAGTTCATGCCGACCAGCCTGCGCGAGTATGCGATCGACTATGACGGCAACGGCCGCATCGAT
CTGCGCAACAGCCCCACCGACGCCATCGGCAGCGTCGGCCGCTTTCTGCAGTTGCACGGCTGGGAAGCAAACCGGCCCGT
GGTCTGGCGCCTGGCCAACGATGAAGGCAGCCGCGGCATTGCGGCGGCGGCGGCCGACGGCGAGCCGTGGCCGACACGGA
CGCTGAACCAGCTTACCCGCGCGGGATTGCGTCTCGATGAGCCCGTCGACCTCGCGCGCGAAGGCGAAACCGGCGTCCTG
GTGGTCGACCTGCCCACCCCCGATCAGCCCACCGAGTACATGATCGGCCTGCGCAACTTCTATGTGCTGACCCGCTACAA
CCGCAGCTTCTTCTACGCGCTCTCGGTGTACCAACTGGGCGAAGCCGTCAAGGCTGCAATGGGCTGA

Upstream 100 bases:

>100_bases
GGCGCCATATCCGCGGCAATTGAGCGGCAGACAGGCGGCAGTTCGGCGTCGGAGCGTGCAGTGCCATCCGCTATACTCGC
TGCGACTTGCTAAGGACACC

Downstream 100 bases:

>100_bases
CGCCCAGGCCTGTCGCCGGATACGCTACCGCCTGCCAGCACTCGCCGGCAGGCGGCATCACCGCGCCCGGCAATTGTGCG
CCAAAAGCCACCGCAGTTTT

Product: lytic murein transglycosylase B

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTDTQRSLRRPLLGAALSAAALGLCGLSPSLLAAGKRRVSVREEEIEPGRYRDNAQTRAFIEDMVTRHGFDRGTLEGWFG
QAVYSATVVRLVMPPTTPGRKSWRAYRSRFIEPIRINAGMRFWQENRDTLRRAEAEFGVPASVIVGIIGVETIYGRDMGT
FRVIDSLSTLAFDYPSTPNRDARATLFRNQLADYLIWCRDTRTDVFSVLGSFAGAIGIPQFMPTSLREYAIDYDGNGRID
LRNSPTDAIGSVGRFLQLHGWEANRPVVWRLANDEGSRGIAAAAADGEPWPTRTLNQLTRAGLRLDEPVDLAREGETGVL
VVDLPTPDQPTEYMIGLRNFYVLTRYNRSFFYALSVYQLGEAVKAAMG

Sequences:

>Translated_368_residues
MTDTQRSLRRPLLGAALSAAALGLCGLSPSLLAAGKRRVSVREEEIEPGRYRDNAQTRAFIEDMVTRHGFDRGTLEGWFG
QAVYSATVVRLVMPPTTPGRKSWRAYRSRFIEPIRINAGMRFWQENRDTLRRAEAEFGVPASVIVGIIGVETIYGRDMGT
FRVIDSLSTLAFDYPSTPNRDARATLFRNQLADYLIWCRDTRTDVFSVLGSFAGAIGIPQFMPTSLREYAIDYDGNGRID
LRNSPTDAIGSVGRFLQLHGWEANRPVVWRLANDEGSRGIAAAAADGEPWPTRTLNQLTRAGLRLDEPVDLAREGETGVL
VVDLPTPDQPTEYMIGLRNFYVLTRYNRSFFYALSVYQLGEAVKAAMG
>Mature_367_residues
TDTQRSLRRPLLGAALSAAALGLCGLSPSLLAAGKRRVSVREEEIEPGRYRDNAQTRAFIEDMVTRHGFDRGTLEGWFGQ
AVYSATVVRLVMPPTTPGRKSWRAYRSRFIEPIRINAGMRFWQENRDTLRRAEAEFGVPASVIVGIIGVETIYGRDMGTF
RVIDSLSTLAFDYPSTPNRDARATLFRNQLADYLIWCRDTRTDVFSVLGSFAGAIGIPQFMPTSLREYAIDYDGNGRIDL
RNSPTDAIGSVGRFLQLHGWEANRPVVWRLANDEGSRGIAAAAADGEPWPTRTLNQLTRAGLRLDEPVDLAREGETGVLV
VDLPTPDQPTEYMIGLRNFYVLTRYNRSFFYALSVYQLGEAVKAAMG

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=328, Percent_Identity=40.5487804878049, Blast_Score=222, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 41025; Mature: 40894

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTQRSLRRPLLGAALSAAALGLCGLSPSLLAAGKRRVSVREEEIEPGRYRDNAQTRAF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHCCCCHHHCCCCCCCCCHHHHHH
IEDMVTRHGFDRGTLEGWFGQAVYSATVVRLVMPPTTPGRKSWRAYRSRFIEPIRINAGM
HHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCH
RFWQENRDTLRRAEAEFGVPASVIVGIIGVETIYGRDMGTFRVIDSLSTLAFDYPSTPNR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCCCC
DARATLFRNQLADYLIWCRDTRTDVFSVLGSFAGAIGIPQFMPTSLREYAIDYDGNGRID
CHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEECCCCEEE
LRNSPTDAIGSVGRFLQLHGWEANRPVVWRLANDEGSRGIAAAAADGEPWPTRTLNQLTR
ECCCCCHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHH
AGLRLDEPVDLAREGETGVLVVDLPTPDQPTEYMIGLRNFYVLTRYNRSFFYALSVYQLG
HCCCCCCCHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHEEEEEEECCEEEEEHHHHHHH
EAVKAAMG
HHHHHHCC
>Mature Secondary Structure 
TDTQRSLRRPLLGAALSAAALGLCGLSPSLLAAGKRRVSVREEEIEPGRYRDNAQTRAF
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHCCCCHHHCCCCCCCCCHHHHHH
IEDMVTRHGFDRGTLEGWFGQAVYSATVVRLVMPPTTPGRKSWRAYRSRFIEPIRINAGM
HHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCH
RFWQENRDTLRRAEAEFGVPASVIVGIIGVETIYGRDMGTFRVIDSLSTLAFDYPSTPNR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCCCC
DARATLFRNQLADYLIWCRDTRTDVFSVLGSFAGAIGIPQFMPTSLREYAIDYDGNGRID
CHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEECCCCEEE
LRNSPTDAIGSVGRFLQLHGWEANRPVVWRLANDEGSRGIAAAAADGEPWPTRTLNQLTR
ECCCCCHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHH
AGLRLDEPVDLAREGETGVLVVDLPTPDQPTEYMIGLRNFYVLTRYNRSFFYALSVYQLG
HCCCCCCCHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHEEEEEEECCEEEEEHHHHHHH
EAVKAAMG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]