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The map label for this gene is iorA [H]

Identifier: 73542201

GI number: 73542201

Start: 2756812

End: 2757342

Strand: Direct

Name: iorA [H]

Synonym: Reut_A2516

Alternate gene names: 73542201

Gene position: 2756812-2757342 (Clockwise)

Preceding gene: 73542200

Following gene: 73542202

Centisome position: 72.42

GC content: 67.8

Gene sequence:

>531_bases
ATGCGTGATGTTCAAAACCGCCCCCTGCCCCCGATGAACGCGCCCCGCCCGCTGACGCTCCATGTCAACCACGCCGAGCA
CACGCTCTGCGTGGCGCCAGACACGCCGCTGCTCTATATCCTGCGCAACGACCTGGCCTGCAATGGCCCGAAGTATGGCT
GCGGACTGGGGCAGTGCGGCGCGTGCACGGTACTGGTGGACGGCACCGCCGCGCGATCGTGCGTGCTGCCGGTGAAGGCG
GTGGTGGGCCACGCCGTGACCACGCTGGAGGGTCTCGGCACAGCCGCACAAGCCGACCCCGTGCAGCAGGCATTCATTGA
CGAGCAGGCCGCGCAGTGCGGCTATTGCCTCAACGGCATGATCATGACCGCCAAGGCGCTGCTGGCCGACAACCCCGACC
CGAGCGAAGCGGAGATCCTCGAGGCGCTGCGCTTTAACCTGTGCCGCTGCGGCACACACGTGGAAATCGTGCGTGCGGTG
CAGCGCGCCGCCGTGCTGCAGCGCGAGCATGCGCAAGGAGCACAACGGTGA

Upstream 100 bases:

>100_bases
CATGATGTCCGCCTGAAACCGAACTGCCTGCATGGCGGCCTTGCCGCCGTGCGGGTCCGAAGCGCCGCAGCCCCTCGCCA
TGAAGGGGCGCGACGCAGCG

Downstream 100 bases:

>100_bases
CCGACGCGCTGGCGCCCCGCATGACTGCCGCCACGCCTGCGATGACGGACAGTCGGCCACCCTTTGCGCAATGCCTGGCC
GCACATGTGTTGCGACCGCC

Product: ferredoxin:(2Fe-2S)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRDVQNRPLPPMNAPRPLTLHVNHAEHTLCVAPDTPLLYILRNDLACNGPKYGCGLGQCGACTVLVDGTAARSCVLPVKA
VVGHAVTTLEGLGTAAQADPVQQAFIDEQAAQCGYCLNGMIMTAKALLADNPDPSEAEILEALRFNLCRCGTHVEIVRAV
QRAAVLQREHAQGAQR

Sequences:

>Translated_176_residues
MRDVQNRPLPPMNAPRPLTLHVNHAEHTLCVAPDTPLLYILRNDLACNGPKYGCGLGQCGACTVLVDGTAARSCVLPVKA
VVGHAVTTLEGLGTAAQADPVQQAFIDEQAAQCGYCLNGMIMTAKALLADNPDPSEAEILEALRFNLCRCGTHVEIVRAV
QRAAVLQREHAQGAQR
>Mature_176_residues
MRDVQNRPLPPMNAPRPLTLHVNHAEHTLCVAPDTPLLYILRNDLACNGPKYGCGLGQCGACTVLVDGTAARSCVLPVKA
VVGHAVTTLEGLGTAAQADPVQQAFIDEQAAQCGYCLNGMIMTAKALLADNPDPSEAEILEALRFNLCRCGTHVEIVRAV
QRAAVLQREHAQGAQR

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=143, Percent_Identity=37.0629370629371, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI71773480, Length=92, Percent_Identity=38.0434782608696, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=39.2638036809816, Blast_Score=106, Evalue=7e-25,
Organism=Escherichia coli, GI1789232, Length=153, Percent_Identity=39.8692810457516, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=145, Percent_Identity=39.3103448275862, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=140, Percent_Identity=37.1428571428571, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=141, Percent_Identity=37.5886524822695, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17737937, Length=140, Percent_Identity=37.1428571428571, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647199, Length=139, Percent_Identity=30.2158273381295, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 18745; Mature: 18745

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDVQNRPLPPMNAPRPLTLHVNHAEHTLCVAPDTPLLYILRNDLACNGPKYGCGLGQCG
CCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCC
ACTVLVDGTAARSCVLPVKAVVGHAVTTLEGLGTAAQADPVQQAFIDEQAAQCGYCLNGM
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IMTAKALLADNPDPSEAEILEALRFNLCRCGTHVEIVRAVQRAAVLQREHAQGAQR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRDVQNRPLPPMNAPRPLTLHVNHAEHTLCVAPDTPLLYILRNDLACNGPKYGCGLGQCG
CCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCC
ACTVLVDGTAARSCVLPVKAVVGHAVTTLEGLGTAAQADPVQQAFIDEQAAQCGYCLNGM
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IMTAKALLADNPDPSEAEILEALRFNLCRCGTHVEIVRAVQRAAVLQREHAQGAQR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]