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The map label for this gene is kipA [H]

Identifier: 73542136

GI number: 73542136

Start: 2687907

End: 2689568

Strand: Direct

Name: kipA [H]

Synonym: Reut_A2450

Alternate gene names: 73542136

Gene position: 2687907-2689568 (Clockwise)

Preceding gene: 73542135

Following gene: 73542137

Centisome position: 70.61

GC content: 70.04

Gene sequence:

>1662_bases
TTGCGTTTCCTTCCTGTCTCACTGAACGCCGTGCTGGTGGAGCTGTCCGACCTGGACCAGACGCTGGCCCTGCTGGCCTC
GCTGCAGCGCGATCCGCTTCCCGGCGTGGAAGAACTGGTCCCCGCCGCGCGCACGATCCACGTGCGCTTTCGCCCCGCAT
CCTGTGGCCTGTCACAGCTAGTACACGCCATCTCCACGCGCAATGTGGCATCGCGCGCGCAGCGCGGCAGTACGCTGATC
GAAATCCCCGTACGCTACGACGGCGAGGATTTGGCAGAGGTCGCGCAACTGCTGGGCATCACGCAAGAAGAAGTCGTGCG
GCGCCACACAGGCAGCGAATACACCGTCGCCTTCACCGGCTTTGCACCGGGCTTTGCGTACCTGTCAGGCGGTCACCCGA
GCCTCGATGTGCCGCGCCGCAGTACCCCGCGCACGCGCATTCCGGCCGGCACGGTGGGCCTGGCCGGCACCTTCAGCGGC
GTGTACCCGCAGGCCAGCCCCGGTGGCTGGCAGATCATCGGCGTGACGCCTGTTGCCATGTGGGACCTGGGACGCGAGCA
GCCCGCGTTGTTGCAGCCTGGCTACCGCGTGCGCTTCGTCGATATCGCCACGCTGGATGCCACGGCGCAAGCCGCCATCC
GGACCGAGACATTGCAAGGCACCGTCCCCGCACCCGCCAGCGACCGCACCCGCGACGCGCTGGCGCCAGGGCAGACCGCT
CTGCAGGTCAAAGCGACCGGCCTGATGACCATGTTTCAGGATCTGGGCCGCCACGGCCAGGCAGGCCAGGGGGTCTCGGC
CTCCGGCGCCATGGATCAGGCCGCCCTCAAGCTGGCCAACCGGCTCGTGGGCAATCCCAGCGACATTGCTGCGCTCGAGA
CCGTGGGCGGTGGCCTGCAACTGCAAAGCCTCGGCGAGACCGTGGTTGCCGTGACCGGTGCCGACGCGCCGCTGACGCTG
CGCACGGCGGATGGCCACCAGTGGAATCCGCCTTCCCATCAGGCGCTCGCGCTCGCCGACGGCGACGTACTGAGCATTGG
CCAGCCCACCGCCGGGGCGCGCAGCTACGTGGCCGCGCGCGGCGGCTTTGCAGTCGCGCCCGTGCTGGGCAGTTGCGCCA
CCGACACGCTCGCCGGCGTGGGCCCCTTGCCGTTGGCCGTGGGAAATGTCCTGGGTCTGCACCCCGCATCGGCCGGCATG
GTGGTGAGCGAGCCGGCCCTGCCCGCCGCGGATCTGCCCACGCTGGAACAGGAGGTGCTGCTCGATGTGGTCATGGGCCC
CCGCACCGACTGGTTCACGCCTGAAGCCGTGGCACGCCTGGCCGCGCAGCGCTGGCAGGTGACGCCCCAATCCAACCGTG
TCGGCCTGCGACTGGCCGGCGATACGCCGCTCGACCGCGCCATCGGCGGCGAACTGCCCAGCGAAGGCACGGCCCTAGGC
GCGTTGCAGGTGCCACCGAGCGGCCAGCCGGTGCTGTTCCTGGCCGACCACCCGCTCACCGGCGGCTACCCGGTGATTGC
CACGGTCGCCCCCTATCACCTCGACCGCGCTGGTCAGATCCCCGTGGGCGCCTGGCTGCGCTTCAACCCGATCCGCGCGT
TTGAAGCACTCTCTCCGGCCGCCGCCCAGCGCGAAGCCGGCACCTTCCGAGATCTCCGATGA

Upstream 100 bases:

>100_bases
GTCGGGTGTTCCGTTCGCCGTGACCCATGCCCCGGGCCATATGTTCGTCACGGACGTGCCCGACAGTACCTATCACGTCT
GATCGCTTGCGGAGTCTCAG

Downstream 100 bases:

>100_bases
AAAAAGTCCTGATTGCCAACCGCGGCGAAATCGCCGTCCGCGTCGTCCGCGCCTGTGCCGACTACGGCGTGCAGTCCGTT
GCCGTGTACGCCAACGCCGA

Product: allophanate hydrolase subunit 2

Products: NA

Alternate protein names: Protein kipA [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MRFLPVSLNAVLVELSDLDQTLALLASLQRDPLPGVEELVPAARTIHVRFRPASCGLSQLVHAISTRNVASRAQRGSTLI
EIPVRYDGEDLAEVAQLLGITQEEVVRRHTGSEYTVAFTGFAPGFAYLSGGHPSLDVPRRSTPRTRIPAGTVGLAGTFSG
VYPQASPGGWQIIGVTPVAMWDLGREQPALLQPGYRVRFVDIATLDATAQAAIRTETLQGTVPAPASDRTRDALAPGQTA
LQVKATGLMTMFQDLGRHGQAGQGVSASGAMDQAALKLANRLVGNPSDIAALETVGGGLQLQSLGETVVAVTGADAPLTL
RTADGHQWNPPSHQALALADGDVLSIGQPTAGARSYVAARGGFAVAPVLGSCATDTLAGVGPLPLAVGNVLGLHPASAGM
VVSEPALPAADLPTLEQEVLLDVVMGPRTDWFTPEAVARLAAQRWQVTPQSNRVGLRLAGDTPLDRAIGGELPSEGTALG
ALQVPPSGQPVLFLADHPLTGGYPVIATVAPYHLDRAGQIPVGAWLRFNPIRAFEALSPAAAQREAGTFRDLR

Sequences:

>Translated_553_residues
MRFLPVSLNAVLVELSDLDQTLALLASLQRDPLPGVEELVPAARTIHVRFRPASCGLSQLVHAISTRNVASRAQRGSTLI
EIPVRYDGEDLAEVAQLLGITQEEVVRRHTGSEYTVAFTGFAPGFAYLSGGHPSLDVPRRSTPRTRIPAGTVGLAGTFSG
VYPQASPGGWQIIGVTPVAMWDLGREQPALLQPGYRVRFVDIATLDATAQAAIRTETLQGTVPAPASDRTRDALAPGQTA
LQVKATGLMTMFQDLGRHGQAGQGVSASGAMDQAALKLANRLVGNPSDIAALETVGGGLQLQSLGETVVAVTGADAPLTL
RTADGHQWNPPSHQALALADGDVLSIGQPTAGARSYVAARGGFAVAPVLGSCATDTLAGVGPLPLAVGNVLGLHPASAGM
VVSEPALPAADLPTLEQEVLLDVVMGPRTDWFTPEAVARLAAQRWQVTPQSNRVGLRLAGDTPLDRAIGGELPSEGTALG
ALQVPPSGQPVLFLADHPLTGGYPVIATVAPYHLDRAGQIPVGAWLRFNPIRAFEALSPAAAQREAGTFRDLR
>Mature_553_residues
MRFLPVSLNAVLVELSDLDQTLALLASLQRDPLPGVEELVPAARTIHVRFRPASCGLSQLVHAISTRNVASRAQRGSTLI
EIPVRYDGEDLAEVAQLLGITQEEVVRRHTGSEYTVAFTGFAPGFAYLSGGHPSLDVPRRSTPRTRIPAGTVGLAGTFSG
VYPQASPGGWQIIGVTPVAMWDLGREQPALLQPGYRVRFVDIATLDATAQAAIRTETLQGTVPAPASDRTRDALAPGQTA
LQVKATGLMTMFQDLGRHGQAGQGVSASGAMDQAALKLANRLVGNPSDIAALETVGGGLQLQSLGETVVAVTGADAPLTL
RTADGHQWNPPSHQALALADGDVLSIGQPTAGARSYVAARGGFAVAPVLGSCATDTLAGVGPLPLAVGNVLGLHPASAGM
VVSEPALPAADLPTLEQEVLLDVVMGPRTDWFTPEAVARLAAQRWQVTPQSNRVGLRLAGDTPLDRAIGGELPSEGTALG
ALQVPPSGQPVLFLADHPLTGGYPVIATVAPYHLDRAGQIPVGAWLRFNPIRAFEALSPAAAQREAGTFRDLR

Specific function: Counteracts the inhibitory action of kipI on sporulation. May bind to kipI, preventing its function as an inhibitor of kinase A [H]

COG id: COG1984

COG function: function code E; Allophanate hydrolase subunit 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786930, Length=315, Percent_Identity=33.968253968254, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786929, Length=172, Percent_Identity=43.0232558139535, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319685, Length=348, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003778 [H]

Pfam domain/function: PF02626 AHS2 [H]

EC number: NA

Molecular weight: Translated: 57622; Mature: 57622

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLPVSLNAVLVELSDLDQTLALLASLQRDPLPGVEELVPAARTIHVRFRPASCGLSQL
CEEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEEECCCCCHHHH
VHAISTRNVASRAQRGSTLIEIPVRYDGEDLAEVAQLLGITQEEVVRRHTGSEYTVAFTG
HHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEC
FAPGFAYLSGGHPSLDVPRRSTPRTRIPAGTVGLAGTFSGVYPQASPGGWQIIGVTPVAM
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHE
WDLGREQPALLQPGYRVRFVDIATLDATAQAAIRTETLQGTVPAPASDRTRDALAPGQTA
ECCCCCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEE
LQVKATGLMTMFQDLGRHGQAGQGVSASGAMDQAALKLANRLVGNPSDIAALETVGGGLQ
EEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEE
LQSLGETVVAVTGADAPLTLRTADGHQWNPPSHQALALADGDVLSIGQPTAGARSYVAAR
EECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEECCCEEECCCCCCCCHHHHHCC
GGFAVAPVLGSCATDTLAGVGPLPLAVGNVLGLHPASAGMVVSEPALPAADLPTLEQEVL
CCEEEEHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCCCCEEEECCCCCCCCCCCHHHHHH
LDVVMGPRTDWFTPEAVARLAAQRWQVTPQSNRVGLRLAGDTPLDRAIGGELPSEGTALG
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEE
ALQVPPSGQPVLFLADHPLTGGYPVIATVAPYHLDRAGQIPVGAWLRFNPIRAFEALSPA
EEECCCCCCCEEEEECCCCCCCCEEEEEECCHHCCCCCCCCCCCEEEECHHHHHHHCCCH
AAQREAGTFRDLR
HHHHCCCCCCCCC
>Mature Secondary Structure
MRFLPVSLNAVLVELSDLDQTLALLASLQRDPLPGVEELVPAARTIHVRFRPASCGLSQL
CEEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEEECCCCCHHHH
VHAISTRNVASRAQRGSTLIEIPVRYDGEDLAEVAQLLGITQEEVVRRHTGSEYTVAFTG
HHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEC
FAPGFAYLSGGHPSLDVPRRSTPRTRIPAGTVGLAGTFSGVYPQASPGGWQIIGVTPVAM
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHE
WDLGREQPALLQPGYRVRFVDIATLDATAQAAIRTETLQGTVPAPASDRTRDALAPGQTA
ECCCCCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEE
LQVKATGLMTMFQDLGRHGQAGQGVSASGAMDQAALKLANRLVGNPSDIAALETVGGGLQ
EEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEE
LQSLGETVVAVTGADAPLTLRTADGHQWNPPSHQALALADGDVLSIGQPTAGARSYVAAR
EECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEECCCEEECCCCCCCCHHHHHCC
GGFAVAPVLGSCATDTLAGVGPLPLAVGNVLGLHPASAGMVVSEPALPAADLPTLEQEVL
CCEEEEHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCCCCEEEECCCCCCCCCCCHHHHHH
LDVVMGPRTDWFTPEAVARLAAQRWQVTPQSNRVGLRLAGDTPLDRAIGGELPSEGTALG
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEE
ALQVPPSGQPVLFLADHPLTGGYPVIATVAPYHLDRAGQIPVGAWLRFNPIRAFEALSPA
EEECCCCCCCEEEEECCCCCCCCEEEEEECCHHCCCCCCCCCCCEEEECHHHHHHHCCCH
AAQREAGTFRDLR
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]