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The map label for this gene is 73542135

Identifier: 73542135

GI number: 73542135

Start: 2687076

End: 2687888

Strand: Direct

Name: 73542135

Synonym: Reut_A2449

Alternate gene names: NA

Gene position: 2687076-2687888 (Clockwise)

Preceding gene: 73542134

Following gene: 73542136

Centisome position: 70.59

GC content: 67.28

Gene sequence:

>813_bases
ATGACAAACCACATGCTTGACGAGGTCCGCTCGGCCGCTGTCGCGGCGGCAAGGACCGCGCGCGAGAGTTATCGCGCCGG
CAAGATCCAGCCCACGGCAGGCGTCGCGCCCGGCATGACGCAGGCCAACATGATCGCGCTGCCGCGCGACTGGGCGTGGG
ACTTCCTGCTCTACGCCCAGCGCAATCCCAAGGCGTGCCCGGTGCTCGACGTGATCGAAGCCGGTGCGTATCACACCGTT
CTGGCCGAAGGCGCCGACATCCGCACCGACATTCCGCTTTACCGGGTGTGGCGCAATGGCCGGCTCGTGGAAGAGGTCGC
CGACGCCACGCCGCTGTGGCAGGAGCACCCCGACCTGGTCACGTTCCTGATCGGCTGCAGCTTCACCTTCGAGACACCGC
TGCTGGAAGCGGGCATCGAGGTGCGCCACATCACGGACGGGTCCAACGTGCCGATGTATCGCACCAATCGCCAGTGCCGC
CCCGCCGGGCGCCTGCATGGCGAGCTGGTGGTGTCCATGCGGCCCATTGCCGCCAGCCGCATCGCCGATGCCGCCATGAT
TTCCGGACGCTTTCCGTCGGTGCATGGCGCACCGGTGCACGTGGGCAACCCCGAAGCGCTGGGCATCGCCGACATCCACC
GCCCAGACTTTGGCGATGCGGTGCGCATCGAATCCGGCGAGATTCCTGTCTTCTGGGCCTGCGGTGTCACGCCGCAGGCC
GCGGTGATGGCGTCGGGTGTTCCGTTCGCCGTGACCCATGCCCCGGGCCATATGTTCGTCACGGACGTGCCCGACAGTAC
CTATCACGTCTGA

Upstream 100 bases:

>100_bases
GGCACCGGCCGGCGCCACGCAAGCCGCCGAGCATTGACCCGGGACGGCACGCGATTCGGCTGACCCATGTCTGCCCGCAA
CACGAAGAACGGATATCACC

Downstream 100 bases:

>100_bases
TCGCTTGCGGAGTCTCAGTTGCGTTTCCTTCCTGTCTCACTGAACGCCGTGCTGGTGGAGCTGTCCGACCTGGACCAGAC
GCTGGCCCTGCTGGCCTCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTNHMLDEVRSAAVAAARTARESYRAGKIQPTAGVAPGMTQANMIALPRDWAWDFLLYAQRNPKACPVLDVIEAGAYHTV
LAEGADIRTDIPLYRVWRNGRLVEEVADATPLWQEHPDLVTFLIGCSFTFETPLLEAGIEVRHITDGSNVPMYRTNRQCR
PAGRLHGELVVSMRPIAASRIADAAMISGRFPSVHGAPVHVGNPEALGIADIHRPDFGDAVRIESGEIPVFWACGVTPQA
AVMASGVPFAVTHAPGHMFVTDVPDSTYHV

Sequences:

>Translated_270_residues
MTNHMLDEVRSAAVAAARTARESYRAGKIQPTAGVAPGMTQANMIALPRDWAWDFLLYAQRNPKACPVLDVIEAGAYHTV
LAEGADIRTDIPLYRVWRNGRLVEEVADATPLWQEHPDLVTFLIGCSFTFETPLLEAGIEVRHITDGSNVPMYRTNRQCR
PAGRLHGELVVSMRPIAASRIADAAMISGRFPSVHGAPVHVGNPEALGIADIHRPDFGDAVRIESGEIPVFWACGVTPQA
AVMASGVPFAVTHAPGHMFVTDVPDSTYHV
>Mature_269_residues
TNHMLDEVRSAAVAAARTARESYRAGKIQPTAGVAPGMTQANMIALPRDWAWDFLLYAQRNPKACPVLDVIEAGAYHTVL
AEGADIRTDIPLYRVWRNGRLVEEVADATPLWQEHPDLVTFLIGCSFTFETPLLEAGIEVRHITDGSNVPMYRTNRQCRP
AGRLHGELVVSMRPIAASRIADAAMISGRFPSVHGAPVHVGNPEALGIADIHRPDFGDAVRIESGEIPVFWACGVTPQAA
VMASGVPFAVTHAPGHMFVTDVPDSTYHV

Specific function: Unknown

COG id: COG4336

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0317 family

Homologues:

Organism=Homo sapiens, GI156139135, Length=241, Percent_Identity=30.2904564315353, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI156139133, Length=243, Percent_Identity=30.4526748971193, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI156139131, Length=243, Percent_Identity=30.4526748971193, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI156139129, Length=243, Percent_Identity=30.4526748971193, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI156139137, Length=243, Percent_Identity=28.8065843621399, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2449_CUPPJ (Q46YH2)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_296655.1
- ProteinModelPortal:   Q46YH2
- SMR:   Q46YH2
- GeneID:   3612280
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A2449
- NMPDR:   fig|264198.3.peg.3172
- HOGENOM:   HBG289473
- OMA:   GPMVVSM
- ProtClustDB:   PRK05463
- BioCyc:   REUT264198:REUT_A2449-MONOMER
- HAMAP:   MF_01830
- InterPro:   IPR009906
- InterPro:   IPR016938
- PIRSF:   PIRSF029755

Pfam domain/function: PF07286 DUF1445

EC number: NA

Molecular weight: Translated: 29308; Mature: 29177

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHMLDEVRSAAVAAARTARESYRAGKIQPTAGVAPGMTQANMIALPRDWAWDFLLYAQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEC
RNPKACPVLDVIEAGAYHTVLAEGADIRTDIPLYRVWRNGRLVEEVADATPLWQEHPDLV
CCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCHHHHHHCCCCCHHCCCCCE
TFLIGCSFTFETPLLEAGIEVRHITDGSNVPMYRTNRQCRPAGRLHGELVVSMRPIAASR
EHHHHCCEEECCCHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCEEEEEEECCHHHHH
IADAAMISGRFPSVHGAPVHVGNPEALGIADIHRPDFGDAVRIESGEIPVFWACGVTPQA
HHHHHHHCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCEEEEECCCCCEEEECCCCCCH
AVMASGVPFAVTHAPGHMFVTDVPDSTYHV
HHHCCCCCEEEEECCCEEEEEECCCCCCCC
>Mature Secondary Structure 
TNHMLDEVRSAAVAAARTARESYRAGKIQPTAGVAPGMTQANMIALPRDWAWDFLLYAQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEC
RNPKACPVLDVIEAGAYHTVLAEGADIRTDIPLYRVWRNGRLVEEVADATPLWQEHPDLV
CCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCHHHHHHCCCCCHHCCCCCE
TFLIGCSFTFETPLLEAGIEVRHITDGSNVPMYRTNRQCRPAGRLHGELVVSMRPIAASR
EHHHHCCEEECCCHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCEEEEEEECCHHHHH
IADAAMISGRFPSVHGAPVHVGNPEALGIADIHRPDFGDAVRIESGEIPVFWACGVTPQA
HHHHHHHCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCEEEEECCCCCEEEECCCCCCH
AVMASGVPFAVTHAPGHMFVTDVPDSTYHV
HHHCCCCCEEEEECCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA