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The map label for this gene is trg [H]

Identifier: 73541708

GI number: 73541708

Start: 2213633

End: 2215198

Strand: Reverse

Name: trg [H]

Synonym: Reut_A2020

Alternate gene names: 73541708

Gene position: 2215198-2213633 (Counterclockwise)

Preceding gene: 73541709

Following gene: 73541707

Centisome position: 58.19

GC content: 63.67

Gene sequence:

>1566_bases
ATGTTTCGCAACACTACTATCGGCGCCAGATTGTGGTTCCTGATTGTCGTCACCAACCTCCTTCTGTTGATTGTCGGAGC
CTTCGGCATGATCGGCATGTCGCGTAGCAATGATGCTACGCACGAAATCTATGAGCACCAGTTGACCGCCGCCATGCGCC
TCGCGGAGGCCCGTTCCAACCAGTTGCTGGTCCGTGTATTGCTCGACCAGGCGACGCTTGCCAAGGATCCCGCCGATGCG
CGCGCGCGCGCCGAAACGGCGCAGGGTTTCGCGCGCGATTCGGAGACCGCGTGGAAGGCTTACCTCGCCGTGCCTCGCTC
CGCGGAAGAATCGAACCTGACGCAGGATGTCTCTGCCAAGCGGGAAGCGTTGTTCTCGCAAGGCGTTGCGCCGATGGTTG
CGGCGTTGAGGGCCGGCGACCGCGAAGCGGTGATGACGTCGGTGATGAAAACCATTCCAAAGCTCGACATCGCGCTGACT
GCAGCCAGCGGCGATCTGAGTCGCGCGCAGATCGCGAGTGCGCACCGCGTGTACGAAGAATCGCAGCAGCGCTACAACGA
GTTGCTCGTGTGGTCAGCGGTGGTGCTCGTTGCCGGCCTGGTCTTCAGCACAGTAGTGGCATGGCGTCTGCGCCGTTCTA
TCGTGCAGCCTCTGGACGTTGCCATCGCGCGATTCGAGCGCATTGCAGATGGCGATCTCAGTGGCGCTGCCACCGATGCC
GGCATCGTTGCCGACGAAAAGGCGCGCAGCGAAACCAGCCGCATGCTTGGCATGCTCGGCAATATGCAGGCCAGCCTGGT
GTCCATGGTCAGCCAGGTCAACGGCGGTGCGGATTCGATCGCCGCGGCCAGCCGGCAGATTGCGAGCGGCAATGCCGACC
TGTCGCAGCGCACGGAACAGCAGGCCGCGTCGCTGGAAGAAACGGCGTCTAGCATGGAAGAACTGACCGGCACGGTACGC
CAGAACGCCGACAGCGCGCGCGAAGCGGCGACCCTCGCCAACGACGCGACGACGCTCGCCGAGCGCGGCAGCGAAGCGGT
GCTGCGCGTGGTGCATACGATGCAGTCGATCGACGCAAGTTCGGGCAAGATCGTCGACATCATCGACGTGATCGAGAAGA
TCGCATTCCAGACCAACATCCTCGCTTTGAATGCGGCGGTAGAAGCCGCCCGGGCAGGCGAGCATGGTCGGGGCTTCGCG
GTGGTCGCGGGCGATGTGCGCGATCTCGCGCAACGTTGTGCGGGCGCTTCGAAGGAAATCCGCGGACTCATCGGCAAATC
GGTGGCCAATGTGCGCGAGGGCACGGGTCTTGTGGATGACGCGGGCCGTGTGATGCAGGACATCGTCGATGCCGTGCGGC
GCGTGAGCGCGATCATCCGCGATATCAGTTCTGCGTCGGACGAGCAGTCCAACGGCATCGAGCAGGTGAACCTCGCGGTG
TCGCACATGGATGGCATGACGCAGCAGAACGCAGCACTGGTGGAGCAGGCCGCTGCCGCGGCAGCATCGCTTCAGGATCA
GGCGCAGCGGCTGATGTCGCTGGTGTCGACGTTCCGGCTCGCGTGA

Upstream 100 bases:

>100_bases
TCAGTTCTGTCTGTCGTCAGGTAAGGGTCAAGGAACGATCGGGAGCGCCGTAGACCAGCAGGACGGCCGGTCGGGCCGTT
CCCTTTACCCCGGAGAGCCC

Downstream 100 bases:

>100_bases
CGATACAAGGCTGTGACGCGTGTGCGGATGCCGCACATGCAGCGCTCCCGCGCGAATGATCGGCGTAGAATCGCGGCTTG
CATTTGCGTAGGAGAGCATC

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MFRNTTIGARLWFLIVVTNLLLLIVGAFGMIGMSRSNDATHEIYEHQLTAAMRLAEARSNQLLVRVLLDQATLAKDPADA
RARAETAQGFARDSETAWKAYLAVPRSAEESNLTQDVSAKREALFSQGVAPMVAALRAGDREAVMTSVMKTIPKLDIALT
AASGDLSRAQIASAHRVYEESQQRYNELLVWSAVVLVAGLVFSTVVAWRLRRSIVQPLDVAIARFERIADGDLSGAATDA
GIVADEKARSETSRMLGMLGNMQASLVSMVSQVNGGADSIAAASRQIASGNADLSQRTEQQAASLEETASSMEELTGTVR
QNADSAREAATLANDATTLAERGSEAVLRVVHTMQSIDASSGKIVDIIDVIEKIAFQTNILALNAAVEAARAGEHGRGFA
VVAGDVRDLAQRCAGASKEIRGLIGKSVANVREGTGLVDDAGRVMQDIVDAVRRVSAIIRDISSASDEQSNGIEQVNLAV
SHMDGMTQQNAALVEQAAAAAASLQDQAQRLMSLVSTFRLA

Sequences:

>Translated_521_residues
MFRNTTIGARLWFLIVVTNLLLLIVGAFGMIGMSRSNDATHEIYEHQLTAAMRLAEARSNQLLVRVLLDQATLAKDPADA
RARAETAQGFARDSETAWKAYLAVPRSAEESNLTQDVSAKREALFSQGVAPMVAALRAGDREAVMTSVMKTIPKLDIALT
AASGDLSRAQIASAHRVYEESQQRYNELLVWSAVVLVAGLVFSTVVAWRLRRSIVQPLDVAIARFERIADGDLSGAATDA
GIVADEKARSETSRMLGMLGNMQASLVSMVSQVNGGADSIAAASRQIASGNADLSQRTEQQAASLEETASSMEELTGTVR
QNADSAREAATLANDATTLAERGSEAVLRVVHTMQSIDASSGKIVDIIDVIEKIAFQTNILALNAAVEAARAGEHGRGFA
VVAGDVRDLAQRCAGASKEIRGLIGKSVANVREGTGLVDDAGRVMQDIVDAVRRVSAIIRDISSASDEQSNGIEQVNLAV
SHMDGMTQQNAALVEQAAAAAASLQDQAQRLMSLVSTFRLA
>Mature_521_residues
MFRNTTIGARLWFLIVVTNLLLLIVGAFGMIGMSRSNDATHEIYEHQLTAAMRLAEARSNQLLVRVLLDQATLAKDPADA
RARAETAQGFARDSETAWKAYLAVPRSAEESNLTQDVSAKREALFSQGVAPMVAALRAGDREAVMTSVMKTIPKLDIALT
AASGDLSRAQIASAHRVYEESQQRYNELLVWSAVVLVAGLVFSTVVAWRLRRSIVQPLDVAIARFERIADGDLSGAATDA
GIVADEKARSETSRMLGMLGNMQASLVSMVSQVNGGADSIAAASRQIASGNADLSQRTEQQAASLEETASSMEELTGTVR
QNADSAREAATLANDATTLAERGSEAVLRVVHTMQSIDASSGKIVDIIDVIEKIAFQTNILALNAAVEAARAGEHGRGFA
VVAGDVRDLAQRCAGASKEIRGLIGKSVANVREGTGLVDDAGRVMQDIVDAVRRVSAIIRDISSASDEQSNGIEQVNLAV
SHMDGMTQQNAALVEQAAAAAASLQDQAQRLMSLVSTFRLA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=533, Percent_Identity=41.0881801125704, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1788194, Length=529, Percent_Identity=40.4536862003781, Blast_Score=295, Evalue=7e-81,
Organism=Escherichia coli, GI1788195, Length=314, Percent_Identity=56.3694267515924, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI2367378, Length=538, Percent_Identity=39.5910780669145, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1789453, Length=331, Percent_Identity=38.0664652567976, Blast_Score=181, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55359; Mature: 55359

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00018 EF_HAND_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRNTTIGARLWFLIVVTNLLLLIVGAFGMIGMSRSNDATHEIYEHQLTAAMRLAEARSN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
QLLVRVLLDQATLAKDPADARARAETAQGFARDSETAWKAYLAVPRSAEESNLTQDVSAK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHCCHHHHHHH
REALFSQGVAPMVAALRAGDREAVMTSVMKTIPKLDIALTAASGDLSRAQIASAHRVYEE
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHH
SQQRYNELLVWSAVVLVAGLVFSTVVAWRLRRSIVQPLDVAIARFERIADGDLSGAATDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GIVADEKARSETSRMLGMLGNMQASLVSMVSQVNGGADSIAAASRQIASGNADLSQRTEQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHH
QAASLEETASSMEELTGTVRQNADSAREAATLANDATTLAERGSEAVLRVVHTMQSIDAS
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
SGKIVDIIDVIEKIAFQTNILALNAAVEAARAGEHGRGFAVVAGDVRDLAQRCAGASKEI
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCHHHH
RGLIGKSVANVREGTGLVDDAGRVMQDIVDAVRRVSAIIRDISSASDEQSNGIEQVNLAV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHH
SHMDGMTQQNAALVEQAAAAAASLQDQAQRLMSLVSTFRLA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFRNTTIGARLWFLIVVTNLLLLIVGAFGMIGMSRSNDATHEIYEHQLTAAMRLAEARSN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
QLLVRVLLDQATLAKDPADARARAETAQGFARDSETAWKAYLAVPRSAEESNLTQDVSAK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHCCHHHHHHH
REALFSQGVAPMVAALRAGDREAVMTSVMKTIPKLDIALTAASGDLSRAQIASAHRVYEE
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHH
SQQRYNELLVWSAVVLVAGLVFSTVVAWRLRRSIVQPLDVAIARFERIADGDLSGAATDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GIVADEKARSETSRMLGMLGNMQASLVSMVSQVNGGADSIAAASRQIASGNADLSQRTEQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHH
QAASLEETASSMEELTGTVRQNADSAREAATLANDATTLAERGSEAVLRVVHTMQSIDAS
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
SGKIVDIIDVIEKIAFQTNILALNAAVEAARAGEHGRGFAVVAGDVRDLAQRCAGASKEI
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCHHHH
RGLIGKSVANVREGTGLVDDAGRVMQDIVDAVRRVSAIIRDISSASDEQSNGIEQVNLAV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHH
SHMDGMTQQNAALVEQAAAAAASLQDQAQRLMSLVSTFRLA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]