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The map label for this gene is paaG [C]

Identifier: 73541707

GI number: 73541707

Start: 2212450

End: 2213532

Strand: Reverse

Name: paaG [C]

Synonym: Reut_A2019

Alternate gene names: 73541707

Gene position: 2213532-2212450 (Counterclockwise)

Preceding gene: 73541708

Following gene: 73541706

Centisome position: 58.15

GC content: 64.08

Gene sequence:

>1083_bases
ATGACTGACTTCGTCACGACAGAAGTCCAGGGTGGCATCGGCTACCTGACGCTGAACCGGCCGCAGGCGCTCAATGCGCT
GTCGCTGGAGATGATCCGTGCCATGACCGCGGCACTGCAGGCCTGGGTCAATGCACCGGAGGTCGTGGCTGTAGTGGTGG
CGGGGGCCGGTGGCAAGGCATTCTGCGCCGGCGGCGACATTCGCTATTTCCACAAGGCCGCGCATGAAGGCGATCCGCTG
CTCGATCAGTTCTTTGTCGAGGAATACGCGCTCAATTTTCTGATCCACCGCTACGCCAAGCCTTATATCGCGCTGATGGA
CGGTGTCGTCATGGGCGGCGGCATGGGCATTTCGCAAGGGGCGCGCCTGCGCCTCGTCACGGAGCGCACCAAGATGGCCA
TGCCGGAAACCAATATCGGGCTGTTTCCGGACGTGGGTGGGGGCTGGTTCCTCGCGCGTACGCCGGGCCGCATCGGCGAA
TACCTGGGTCTCACCGGCACGGTCATTGCCGCGGCCGATGCGCTCTATGCTGGACTGGCCGACGCCTATCTGCCTTCCAA
TGTACTGGCTGAAGTGGTCAGCGCGCTGCGCGCGCGCACGTTCGACAACGGCCAGGCCGTGCTCGACCACATCGCCACGT
TCGCGCAGCAGCATCGCGATGCGTGCATGCCGGCGCAAAGCCAGCTTGCGGGGCTGTCGGCCGAGATCGACCGTATCTTT
GCCGGGGACACCATGGTCGACATTCTTGCCGCGATCAGCGAGGCGCCGGGCGACTGGGCCGCGCAAACGGCAGCAATGCT
GCGCAGCCGTTCGCCGCTGATGCTGCACGTATCGCTCGAGCAGATCCGCCGTGCGCGCACCATGTCGCTGGACGACGAAC
TTCGCATGGAACTCGACATGATGCACTACGTGTTCCGCAAGGGCGACGGCGTGGAAGGCATCCGTGCGCTCGCTATCGAC
AAGGATCACAAGCCACGCTGGCAGGACGCGCGCGTCGACGACGTGAGTCACGAGAAAGTGCTGTCCTTCTTCGATAGCCC
GTGGCGTGCGGAAGATCACCCGCTGGCCAGTCTCGGCAAGTAA

Upstream 100 bases:

>100_bases
CGATACAAGGCTGTGACGCGTGTGCGGATGCCGCACATGCAGCGCTCCCGCGCGAATGATCGGCGTAGAATCGCGGCTTG
CATTTGCGTAGGAGAGCATC

Downstream 100 bases:

>100_bases
GGGGGTGAGCCACGCGGCTCTCCAGACTCGGGTAGAGTGACGGCTGGATCGGCGCCAGGCATGACAGGCCATCCATGTGG
CCGGCGCCATTCCGCTTCAC

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTDFVTTEVQGGIGYLTLNRPQALNALSLEMIRAMTAALQAWVNAPEVVAVVVAGAGGKAFCAGGDIRYFHKAAHEGDPL
LDQFFVEEYALNFLIHRYAKPYIALMDGVVMGGGMGISQGARLRLVTERTKMAMPETNIGLFPDVGGGWFLARTPGRIGE
YLGLTGTVIAAADALYAGLADAYLPSNVLAEVVSALRARTFDNGQAVLDHIATFAQQHRDACMPAQSQLAGLSAEIDRIF
AGDTMVDILAAISEAPGDWAAQTAAMLRSRSPLMLHVSLEQIRRARTMSLDDELRMELDMMHYVFRKGDGVEGIRALAID
KDHKPRWQDARVDDVSHEKVLSFFDSPWRAEDHPLASLGK

Sequences:

>Translated_360_residues
MTDFVTTEVQGGIGYLTLNRPQALNALSLEMIRAMTAALQAWVNAPEVVAVVVAGAGGKAFCAGGDIRYFHKAAHEGDPL
LDQFFVEEYALNFLIHRYAKPYIALMDGVVMGGGMGISQGARLRLVTERTKMAMPETNIGLFPDVGGGWFLARTPGRIGE
YLGLTGTVIAAADALYAGLADAYLPSNVLAEVVSALRARTFDNGQAVLDHIATFAQQHRDACMPAQSQLAGLSAEIDRIF
AGDTMVDILAAISEAPGDWAAQTAAMLRSRSPLMLHVSLEQIRRARTMSLDDELRMELDMMHYVFRKGDGVEGIRALAID
KDHKPRWQDARVDDVSHEKVLSFFDSPWRAEDHPLASLGK
>Mature_359_residues
TDFVTTEVQGGIGYLTLNRPQALNALSLEMIRAMTAALQAWVNAPEVVAVVVAGAGGKAFCAGGDIRYFHKAAHEGDPLL
DQFFVEEYALNFLIHRYAKPYIALMDGVVMGGGMGISQGARLRLVTERTKMAMPETNIGLFPDVGGGWFLARTPGRIGEY
LGLTGTVIAAADALYAGLADAYLPSNVLAEVVSALRARTFDNGQAVLDHIATFAQQHRDACMPAQSQLAGLSAEIDRIFA
GDTMVDILAAISEAPGDWAAQTAAMLRSRSPLMLHVSLEQIRRARTMSLDDELRMELDMMHYVFRKGDGVEGIRALAIDK
DHKPRWQDARVDDVSHEKVLSFFDSPWRAEDHPLASLGK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=345, Percent_Identity=37.3913043478261, Blast_Score=244, Evalue=8e-65,
Organism=Homo sapiens, GI37594469, Length=296, Percent_Identity=37.8378378378378, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI194097323, Length=215, Percent_Identity=31.6279069767442, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI68989263, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787660, Length=200, Percent_Identity=30, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI221142681, Length=182, Percent_Identity=29.6703296703297, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787659, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788682, Length=201, Percent_Identity=29.3532338308458, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25144157, Length=348, Percent_Identity=39.9425287356322, Blast_Score=238, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI25144160, Length=348, Percent_Identity=39.9425287356322, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17554946, Length=189, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=203, Percent_Identity=39.9014778325123, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571730, Length=332, Percent_Identity=38.5542168674699, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI28571729, Length=332, Percent_Identity=38.5542168674699, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI20129971, Length=196, Percent_Identity=31.1224489795918, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653477, Length=196, Percent_Identity=31.1224489795918, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 39161; Mature: 39030

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFVTTEVQGGIGYLTLNRPQALNALSLEMIRAMTAALQAWVNAPEVVAVVVAGAGGKA
CCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
FCAGGDIRYFHKAAHEGDPLLDQFFVEEYALNFLIHRYAKPYIALMDGVVMGGGMGISQG
EECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
ARLRLVTERTKMAMPETNIGLFPDVGGGWFLARTPGRIGEYLGLTGTVIAAADALYAGLA
CEEEEEEHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHH
DAYLPSNVLAEVVSALRARTFDNGQAVLDHIATFAQQHRDACMPAQSQLAGLSAEIDRIF
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHH
AGDTMVDILAAISEAPGDWAAQTAAMLRSRSPLMLHVSLEQIRRARTMSLDDELRMELDM
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHH
MHYVFRKGDGVEGIRALAIDKDHKPRWQDARVDDVSHEKVLSFFDSPWRAEDHPLASLGK
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TDFVTTEVQGGIGYLTLNRPQALNALSLEMIRAMTAALQAWVNAPEVVAVVVAGAGGKA
CCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
FCAGGDIRYFHKAAHEGDPLLDQFFVEEYALNFLIHRYAKPYIALMDGVVMGGGMGISQG
EECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
ARLRLVTERTKMAMPETNIGLFPDVGGGWFLARTPGRIGEYLGLTGTVIAAADALYAGLA
CEEEEEEHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHH
DAYLPSNVLAEVVSALRARTFDNGQAVLDHIATFAQQHRDACMPAQSQLAGLSAEIDRIF
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHH
AGDTMVDILAAISEAPGDWAAQTAAMLRSRSPLMLHVSLEQIRRARTMSLDDELRMELDM
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHH
MHYVFRKGDGVEGIRALAIDKDHKPRWQDARVDDVSHEKVLSFFDSPWRAEDHPLASLGK
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA