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The map label for this gene is alr [H]

Identifier: 73541623

GI number: 73541623

Start: 2122207

End: 2123328

Strand: Reverse

Name: alr [H]

Synonym: Reut_A1934

Alternate gene names: 73541623

Gene position: 2123328-2122207 (Counterclockwise)

Preceding gene: 73541625

Following gene: 73541622

Centisome position: 55.78

GC content: 67.47

Gene sequence:

>1122_bases
ATGCCAAGACCGATCCACGCCGTCATCCATCAACCCGCCATTGCGAACAACCTTGAGGTCGTCCGCCGTCACGCCCCCGG
TTCCCGCGTATGGGCCGTCATCAAGGCCAATGCCTATGGCCATGGGATCCGCCGTGTGTTCGCCGGCCTGCGTGGAACGG
ACGGCTTCGGGCTGCTCGACCTGAACGAAGCCGTGCAGCTGCGCGACCTCGGCTGGCAAGGCCCGATCCTGTTGCTGGAG
GGGTTTTTCCAACCGCAGGACGTGCCGCTCCTTGAACAATACCGGCTCACCACCGCGGTGCATTGCGACGAGCAGCTCCG
GATGCTGGAGAGCGCACGCCCGAAGGGTCCGCTGGCGATCCAGCTCAAACTCAATACGGGGATGAACCGCCTGGGCTTCC
ACCCGTCGCAATACCGCACGGCGTGGGAGCGCGCACGCGCCATGCCCTGCGTGGGCAGTATCGTCCACATGACGCACTTT
TCCGATGCCGACACCCCGCGTGGCATCGCCCACCAGATCGAGGCCTTCGACAAAGCCACGGCCAACCTGCCAGGTGAGGC
CAGCCTGTCGAACTCCGCGGCGGTCCTGTGGCATCCCGAAGCGCACCGCGCATGGGTGAGGCCCGGTGTCATCCTGTATG
GCGCATCGCCGACCGGCCGCGAGGCCGACATTGCGGGCGTCGGCCTGCAGCCGGCCATGTCGCTGCACAGCGAGCTGATT
GCGGTCCAGGACCTGCAGCCTGGCGATACGGTCGGCTACGGTTCCATGTTCACCGCCGACCGGCCGATGCGCATCGGCGT
GGTGGCCTGTGGCTATGCAGATGGCTACCCGCGGCATGCAACGGGTTGGGGCGAACACCGCGCCCCCGTGCTGGTGGACG
GCGTGCGCACCCAACTCGTGGGCCGCGTGTCGATGGACATGCTGTGCGTAGACCTGGGGCCATGCCCGAAGGCGAGGATC
GGCAGTCCTGTCACGTTGTGGGGCCAGGGCCTGCCGATCGACGATGTCGCGCAGGCCAGCGGCACGGTGGGTTACGAACT
GATGTGCGCGCTGGCGCCGCGCGTGCCGACCACGGTGGCAACCATTACGGCGCCGGACAGCGCCTCGCCGCTGCTGGCCT
GA

Upstream 100 bases:

>100_bases
AAGTGACGCCCGGTGACATCCGGTGACGCCCGCATCACGCCGCGGCGTCTAGAGGATTCCTACCACCGGCAGCGATGCTT
GCCTCGCGAGATGTGACTTC

Downstream 100 bases:

>100_bases
GTGCTACCCTGACCGGATCTGTCCTGACGGCCGGCTGCCATGCGGTGGCCGGCCGTCGCGTTTCCGCTATCCCAATCCAA
GGATCTTCCATTGGCCAAGA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MPRPIHAVIHQPAIANNLEVVRRHAPGSRVWAVIKANAYGHGIRRVFAGLRGTDGFGLLDLNEAVQLRDLGWQGPILLLE
GFFQPQDVPLLEQYRLTTAVHCDEQLRMLESARPKGPLAIQLKLNTGMNRLGFHPSQYRTAWERARAMPCVGSIVHMTHF
SDADTPRGIAHQIEAFDKATANLPGEASLSNSAAVLWHPEAHRAWVRPGVILYGASPTGREADIAGVGLQPAMSLHSELI
AVQDLQPGDTVGYGSMFTADRPMRIGVVACGYADGYPRHATGWGEHRAPVLVDGVRTQLVGRVSMDMLCVDLGPCPKARI
GSPVTLWGQGLPIDDVAQASGTVGYELMCALAPRVPTTVATITAPDSASPLLA

Sequences:

>Translated_373_residues
MPRPIHAVIHQPAIANNLEVVRRHAPGSRVWAVIKANAYGHGIRRVFAGLRGTDGFGLLDLNEAVQLRDLGWQGPILLLE
GFFQPQDVPLLEQYRLTTAVHCDEQLRMLESARPKGPLAIQLKLNTGMNRLGFHPSQYRTAWERARAMPCVGSIVHMTHF
SDADTPRGIAHQIEAFDKATANLPGEASLSNSAAVLWHPEAHRAWVRPGVILYGASPTGREADIAGVGLQPAMSLHSELI
AVQDLQPGDTVGYGSMFTADRPMRIGVVACGYADGYPRHATGWGEHRAPVLVDGVRTQLVGRVSMDMLCVDLGPCPKARI
GSPVTLWGQGLPIDDVAQASGTVGYELMCALAPRVPTTVATITAPDSASPLLA
>Mature_372_residues
PRPIHAVIHQPAIANNLEVVRRHAPGSRVWAVIKANAYGHGIRRVFAGLRGTDGFGLLDLNEAVQLRDLGWQGPILLLEG
FFQPQDVPLLEQYRLTTAVHCDEQLRMLESARPKGPLAIQLKLNTGMNRLGFHPSQYRTAWERARAMPCVGSIVHMTHFS
DADTPRGIAHQIEAFDKATANLPGEASLSNSAAVLWHPEAHRAWVRPGVILYGASPTGREADIAGVGLQPAMSLHSELIA
VQDLQPGDTVGYGSMFTADRPMRIGVVACGYADGYPRHATGWGEHRAPVLVDGVRTQLVGRVSMDMLCVDLGPCPKARIG
SPVTLWGQGLPIDDVAQASGTVGYELMCALAPRVPTTVATITAPDSASPLLA

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=357, Percent_Identity=58.5434173669468, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1790487, Length=351, Percent_Identity=43.5897435897436, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40143; Mature: 40011

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPIHAVIHQPAIANNLEVVRRHAPGSRVWAVIKANAYGHGIRRVFAGLRGTDGFGLLD
CCCCHHHHHCCCCHHCCHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEE
LNEAVQLRDLGWQGPILLLEGFFQPQDVPLLEQYRLTTAVHCDEQLRMLESARPKGPLAI
CCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHEECCHHHHHHHHHCCCCCCEEE
QLKLNTGMNRLGFHPSQYRTAWERARAMPCVGSIVHMTHFSDADTPRGIAHQIEAFDKAT
EEEECCCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
ANLPGEASLSNSAAVLWHPEAHRAWVRPGVILYGASPTGREADIAGVGLQPAMSLHSELI
CCCCCCCCCCCCEEEEECCHHCCCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHHHHE
AVQDLQPGDTVGYGSMFTADRPMRIGVVACGYADGYPRHATGWGEHRAPVLVDGVRTQLV
EEECCCCCCCCCCCCEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHH
GRVSMDMLCVDLGPCPKARIGSPVTLWGQGLPIDDVAQASGTVGYELMCALAPRVPTTVA
HHHCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCCCEEHEECCCCCCCEEE
TITAPDSASPLLA
EEECCCCCCCCCC
>Mature Secondary Structure 
PRPIHAVIHQPAIANNLEVVRRHAPGSRVWAVIKANAYGHGIRRVFAGLRGTDGFGLLD
CCCHHHHHCCCCHHCCHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEE
LNEAVQLRDLGWQGPILLLEGFFQPQDVPLLEQYRLTTAVHCDEQLRMLESARPKGPLAI
CCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHEECCHHHHHHHHHCCCCCCEEE
QLKLNTGMNRLGFHPSQYRTAWERARAMPCVGSIVHMTHFSDADTPRGIAHQIEAFDKAT
EEEECCCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
ANLPGEASLSNSAAVLWHPEAHRAWVRPGVILYGASPTGREADIAGVGLQPAMSLHSELI
CCCCCCCCCCCCEEEEECCHHCCCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHHHHE
AVQDLQPGDTVGYGSMFTADRPMRIGVVACGYADGYPRHATGWGEHRAPVLVDGVRTQLV
EEECCCCCCCCCCCCEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHH
GRVSMDMLCVDLGPCPKARIGSPVTLWGQGLPIDDVAQASGTVGYELMCALAPRVPTTVA
HHHCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCCCEEHEECCCCCCCEEE
TITAPDSASPLLA
EEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA