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The map label for this gene is hexR [C]

Identifier: 73541618

GI number: 73541618

Start: 2116267

End: 2117343

Strand: Reverse

Name: hexR [C]

Synonym: Reut_A1929

Alternate gene names: 73541618

Gene position: 2117343-2116267 (Counterclockwise)

Preceding gene: 73541620

Following gene: 73541617

Centisome position: 55.62

GC content: 67.32

Gene sequence:

>1077_bases
ATGATGAAAACTCTGTTTTCTTGTCCGCGGTCTGCGTGTAAATTCATTTTCATTGCAGCCACCACGACCGATGTTTGGTT
TTCACATCGGCCAGATCTCCTGATACCCATGCCGGACGGCGCCTCGATCTCTGAACGTATTGCGCGCAGCCTGCCAGCGC
TGACGCCCGCACACCAGCGCATGGCCGAGTACGTGCTTGCCAATCCGTTCCGCGCCGCGACGATGCGGATCGACGAGTTC
GCGACCGCGGTGCAGGTGTCGGTGGCGACAGCCAACCGTTTTGCGCGCGCGCTCGGGTTTGACGGCTATCCGCAGTTCCG
CGCCGAACTGGTGCGCGGGTTTGAGGCGACGCTGGCGCCGGTGGAACGGCTGCGTTCGGAGCTGGAGCGGCCCACCACGG
CGGCCGAGGCATTCGCCGCGTCGCTGGACAATGCCGCAGCCAACCTCGAGGCCACGCGCCGCGCGCTGGACGCCGACGCG
TGCGAACGGGCGGTATCCGCGATTCTTGCCGCGGAGCGTGTCTACATTGCCGGCTTTGGCGCAAGCGGCTTCCTGTCGGG
CCTGTTGCAGCACGGCCTGGAAATGCACTGCCGCATGGTGACCTCGGTCGCCGGCGCGGGCGGTGCGTCGCACGCGGCGC
GCCAGTTGTTCAAGCTGAGCCCTGCCGACCTGGTCATCGCCATCGCGTTTCCGCGCTACGTGTCCGCTACCGTGGTGCTG
GCCCAGCGCGCCAAGGCACGCGGCGCGCGCTTGCTGGCGCTGACCGATGGCCCGACCTCGCCGCTGGCGCCGATTGCCGA
TATCGCGCTCTATGCGCAGGCCGCTAACCGGCTGTCGGCCAATTCGGATGCCAACGTGCTGGCGTTGATCGAAGCGCTGT
GCGGCGCCGTGGCACACCGAGCCGAACGCCCGGTCAAGGCCGCGGCCGAGATGACCGAGTTCCTGCTGCCGTGGCTGTAT
GGCCCCCATGCCGGCAATGCCGGCACCACGGCAGCCGCACAGCCCGTGGCATCAGCCGATGTCGATGGCAAGCCCGGCGC
CGACCGCCGCAACCCTTCCAAGCACCCAAAAGCGTAG

Upstream 100 bases:

>100_bases
CGCGGACAGCAGCCCGAGATGAGGCGCTGGGCGGCATTGTAGCGTTTCCCGTTGGCGGTGACCCGCTCGATTGACGGTAT
GTCCTAGGGATTACCCTTGA

Downstream 100 bases:

>100_bases
TCCCAATGAACCAAGCAGTCATTGCCATCCACGGCGGCGCCGGCACGATCACGCGCGCGGCCATGGATTCGGCCCGCGAA
CGCGAATACATCGAAGCGCT

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MMKTLFSCPRSACKFIFIAATTTDVWFSHRPDLLIPMPDGASISERIARSLPALTPAHQRMAEYVLANPFRAATMRIDEF
ATAVQVSVATANRFARALGFDGYPQFRAELVRGFEATLAPVERLRSELERPTTAAEAFAASLDNAAANLEATRRALDADA
CERAVSAILAAERVYIAGFGASGFLSGLLQHGLEMHCRMVTSVAGAGGASHAARQLFKLSPADLVIAIAFPRYVSATVVL
AQRAKARGARLLALTDGPTSPLAPIADIALYAQAANRLSANSDANVLALIEALCGAVAHRAERPVKAAAEMTEFLLPWLY
GPHAGNAGTTAAAQPVASADVDGKPGADRRNPSKHPKA

Sequences:

>Translated_358_residues
MMKTLFSCPRSACKFIFIAATTTDVWFSHRPDLLIPMPDGASISERIARSLPALTPAHQRMAEYVLANPFRAATMRIDEF
ATAVQVSVATANRFARALGFDGYPQFRAELVRGFEATLAPVERLRSELERPTTAAEAFAASLDNAAANLEATRRALDADA
CERAVSAILAAERVYIAGFGASGFLSGLLQHGLEMHCRMVTSVAGAGGASHAARQLFKLSPADLVIAIAFPRYVSATVVL
AQRAKARGARLLALTDGPTSPLAPIADIALYAQAANRLSANSDANVLALIEALCGAVAHRAERPVKAAAEMTEFLLPWLY
GPHAGNAGTTAAAQPVASADVDGKPGADRRNPSKHPKA
>Mature_358_residues
MMKTLFSCPRSACKFIFIAATTTDVWFSHRPDLLIPMPDGASISERIARSLPALTPAHQRMAEYVLANPFRAATMRIDEF
ATAVQVSVATANRFARALGFDGYPQFRAELVRGFEATLAPVERLRSELERPTTAAEAFAASLDNAAANLEATRRALDADA
CERAVSAILAAERVYIAGFGASGFLSGLLQHGLEMHCRMVTSVAGAGGASHAARQLFKLSPADLVIAIAFPRYVSATVVL
AQRAKARGARLLALTDGPTSPLAPIADIALYAQAANRLSANSDANVLALIEALCGAVAHRAERPVKAAAEMTEFLLPWLY
GPHAGNAGTTAAAQPVASADVDGKPGADRRNPSKHPKA

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=227, Percent_Identity=27.3127753303965, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 37830; Mature: 37830

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKTLFSCPRSACKFIFIAATTTDVWFSHRPDLLIPMPDGASISERIARSLPALTPAHQR
CCCHHHHCHHHHHCEEEEEEEEHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCCCHHHHH
MAEYVLANPFRAATMRIDEFATAVQVSVATANRFARALGFDGYPQFRAELVRGFEATLAP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VERLRSELERPTTAAEAFAASLDNAAANLEATRRALDADACERAVSAILAAERVYIAGFG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEEEECC
ASGFLSGLLQHGLEMHCRMVTSVAGAGGASHAARQLFKLSPADLVIAIAFPRYVSATVVL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHH
AQRAKARGARLLALTDGPTSPLAPIADIALYAQAANRLSANSDANVLALIEALCGAVAHR
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AERPVKAAAEMTEFLLPWLYGPHAGNAGTTAAAQPVASADVDGKPGADRRNPSKHPKA
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMKTLFSCPRSACKFIFIAATTTDVWFSHRPDLLIPMPDGASISERIARSLPALTPAHQR
CCCHHHHCHHHHHCEEEEEEEEHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCCCHHHHH
MAEYVLANPFRAATMRIDEFATAVQVSVATANRFARALGFDGYPQFRAELVRGFEATLAP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VERLRSELERPTTAAEAFAASLDNAAANLEATRRALDADACERAVSAILAAERVYIAGFG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEEEECC
ASGFLSGLLQHGLEMHCRMVTSVAGAGGASHAARQLFKLSPADLVIAIAFPRYVSATVVL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHH
AQRAKARGARLLALTDGPTSPLAPIADIALYAQAANRLSANSDANVLALIEALCGAVAHR
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AERPVKAAAEMTEFLLPWLYGPHAGNAGTTAAAQPVASADVDGKPGADRRNPSKHPKA
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]