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The map label for this gene is cdsA [H]

Identifier: 73541565

GI number: 73541565

Start: 2053399

End: 2054220

Strand: Reverse

Name: cdsA [H]

Synonym: Reut_A1876

Alternate gene names: 73541565

Gene position: 2054220-2053399 (Counterclockwise)

Preceding gene: 73541566

Following gene: 73541564

Centisome position: 53.97

GC content: 68.61

Gene sequence:

>822_bases
ATGCTTCTCACCCGCGTCATCACCGCCCTGTGCCTGTTGCTGCTGATCCTGCCGATCCTGTTCCTGGCACCGCCCTCGGC
GCTGGCCGGGCTGGTCGCCGTGATCGTGCTGCTTGGCGGCTGGGAGTTCGGGCGGCTCATCGGGCTGCGCGGCGCCTGGC
CGTACGTGTACGCCGTGGCCTGCCTGCTCGCCTTGATTGGCTGGCATGACCTGCCGGACCGCCATGGCCTGACCAGGCTG
CTGGAGGCTGCCGTGGTCTGCTGGGGCGTGGCGCTTGTACTGCTCGCGCGCGGCGTGCGGACTGCGACGCCGGGGTTCAC
GGTGCTGGGCGCCATCCTCGGCCTCATCATGCTTCCCGCATTCGGGCACGCCATCATGATCCTGCGCAGCGCCGGCATTG
GCGTATTGCTGACAGCGGCCGTGCTGGTGTGGGCGGCGGATATCGGCGCCTATTTTGTCGGCAAGGCCATCGGGCGGCGC
AAGCTCGCCCCTTCCATCAGCCCAGGCAAGTCGTGGGAGGGCGCGATCGGCGGCTGGCTGCTCGCCATGCTGATCGGCCT
GGGTCTGGCCGCCACCCATGCCTTTGCTCCGACCTGGTTCTCCGTGATGGCCGACCGCGGTGGCCTTGCGCTCGTCGCCC
TCTTGACCACGCTGCTGGTTGCGGCGAGCATCGTCGGTGACCTGTTCGAGTCGCTGCTCAAGCGGCAGGTCGGCATGAAG
GACAGCAGCCGGCTGTTGCCTGGCCACGGCGGCGTGCTGGACCGCATTGACGCGCTGGTGCCGGTGTTCCCGCTGGCCGC
GCTGATGGTGACCTATTTCTGA

Upstream 100 bases:

>100_bases
AACGCCGCTTTGGCCGCACCAGCGCGCAGCTGGTGGCGCCGGGGCTGTCCGGCACTGCCTGAGCGGCAGGTCATTCAACT
TTCCACGGGACTAGCAGCGC

Downstream 100 bases:

>100_bases
AGCTGCTCTGTTCTGATATGCATCGAATTACCATCCTGGGCGCTACTGGCTCGATCGGCGAAAGCACGCTCGACGTCGTA
CGGCGCCACGCCGACCGGTA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLLTRVITALCLLLLILPILFLAPPSALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVACLLALIGWHDLPDRHGLTRL
LEAAVVCWGVALVLLARGVRTATPGFTVLGAILGLIMLPAFGHAIMILRSAGIGVLLTAAVLVWAADIGAYFVGKAIGRR
KLAPSISPGKSWEGAIGGWLLAMLIGLGLAATHAFAPTWFSVMADRGGLALVALLTTLLVAASIVGDLFESLLKRQVGMK
DSSRLLPGHGGVLDRIDALVPVFPLAALMVTYF

Sequences:

>Translated_273_residues
MLLTRVITALCLLLLILPILFLAPPSALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVACLLALIGWHDLPDRHGLTRL
LEAAVVCWGVALVLLARGVRTATPGFTVLGAILGLIMLPAFGHAIMILRSAGIGVLLTAAVLVWAADIGAYFVGKAIGRR
KLAPSISPGKSWEGAIGGWLLAMLIGLGLAATHAFAPTWFSVMADRGGLALVALLTTLLVAASIVGDLFESLLKRQVGMK
DSSRLLPGHGGVLDRIDALVPVFPLAALMVTYF
>Mature_273_residues
MLLTRVITALCLLLLILPILFLAPPSALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVACLLALIGWHDLPDRHGLTRL
LEAAVVCWGVALVLLARGVRTATPGFTVLGAILGLIMLPAFGHAIMILRSAGIGVLLTAAVLVWAADIGAYFVGKAIGRR
KLAPSISPGKSWEGAIGGWLLAMLIGLGLAATHAFAPTWFSVMADRGGLALVALLTTLLVAASIVGDLFESLLKRQVGMK
DSSRLLPGHGGVLDRIDALVPVFPLAALMVTYF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=295, Percent_Identity=37.2881355932203, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787677, Length=129, Percent_Identity=40.3100775193798, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28622; Mature: 28622

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTRVITALCLLLLILPILFLAPPSALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVA
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHH
CLLALIGWHDLPDRHGLTRLLEAAVVCWGVALVLLARGVRTATPGFTVLGAILGLIMLPA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FGHAIMILRSAGIGVLLTAAVLVWAADIGAYFVGKAIGRRKLAPSISPGKSWEGAIGGWL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LAMLIGLGLAATHAFAPTWFSVMADRGGLALVALLTTLLVAASIVGDLFESLLKRQVGMK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DSSRLLPGHGGVLDRIDALVPVFPLAALMVTYF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLTRVITALCLLLLILPILFLAPPSALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVA
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHH
CLLALIGWHDLPDRHGLTRLLEAAVVCWGVALVLLARGVRTATPGFTVLGAILGLIMLPA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FGHAIMILRSAGIGVLLTAAVLVWAADIGAYFVGKAIGRRKLAPSISPGKSWEGAIGGWL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LAMLIGLGLAATHAFAPTWFSVMADRGGLALVALLTTLLVAASIVGDLFESLLKRQVGMK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DSSRLLPGHGGVLDRIDALVPVFPLAALMVTYF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]