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The map label for this gene is ybiT [H]

Identifier: 73541533

GI number: 73541533

Start: 2019423

End: 2021045

Strand: Reverse

Name: ybiT [H]

Synonym: Reut_A1844

Alternate gene names: 73541533

Gene position: 2021045-2019423 (Counterclockwise)

Preceding gene: 73541534

Following gene: 73541531

Centisome position: 53.09

GC content: 62.6

Gene sequence:

>1623_bases
GTGCTTTCTACCGCAAACATCACCATGCAGTTCGGCCCCAAGCCGTTGTTCGAGAATATCTCGGTCAAGTTCGGCGAGGG
CAACCGCTACGGCCTGATCGGCGCGAACGGCTGCGGCAAGTCCACCTTCATGAAGATCCTGGGCGGCGATCTCGAATCGT
CCGCAGGCAACGTCATGCTGGAACCGGGCATCCGCCTGGGCAAACTGCGCCAGGACCAGTTCGCGTATGAAGACATGCGC
GTGCTGGACGTCGTCATGATGGGCCACACCGAGATGTGGGCCGCCGCGCAGGAGCGCGACGCGATCTACGCCAACCCGGA
AGCGACCGACGAAGACTACATGAAGGCCGCGGAGCTCGAGGCCAAGTACGCCGAGTACGACGGCTACACGGCCGAAGCGC
GCGCCGGTGAACTGCTGCTGGGCGTGGGCATTCCTACCAGCCAGCACCAGGGCCCGATGAGCGATGTCGCCCCCGGCTGG
AAGCTGCGCGTGCTGCTGGCGCAGGCACTGTTCTCGAACCCGGACGTGCTGTTGCTCGACGAACCGACCAACAACCTGGA
CATCAACACGATCCGCTGGCTGGAGACCGTGCTCAACGAGCGCAACTCCACCATGATCATCATTTCCCACGATCGCCACT
TCCTGAACTCGGTCTGCACGCACATGGCCGACATGGACTACGGCACGTTGAAGGTCTACCCGGGCAACTACGACGACTAC
ATGGAAGCGTCGATGCAGGCCCGCGAGCGCCAGATGGCCGCCAACGCGCGCGCCAAGGAACGCATCAGCGAACTGCAGGA
CTTCGTGCGCCGCTTCTCGGCCAACAAGTCGAAGGCCCGCCAGGCGACCTCGCGTGCCAAGCAGATCGAGAAGATCAAGG
TCGAGGACATCAAGCCGTCGTCGCGCCAGAACCCGTTCATCCGCTTCGAGTTCGAGAAGAAGCTGCACAATCTTGCCGTG
GAAGTCGAAGGCGTCACCAAGACCTACGACCGCAAGATCATCAACAACCTGTCATTGGCGATCCAGGCCGGCGAGCGCGT
GGCAATCATCGGCGAGAACGGCGCGGGCAAGACCACGCTGCTGCGCAGCCTGCTGAACGGTGCAGTACAGACCGGCGTGC
AGCGCGGTGTCGAGGTGGATCGTGGCACGGTCAAGTGGGCCGAGAACGCCAACGTCGGCTACATGCCGCAGGATACCTAC
GAGGAATTCCCCGAAGACCGCGACGTGATGGACTGGATGAGCCAGTGGACGCAGGCGGGCGATGACGAAACGTCGCTGCG
CGGCACGCTGGGCCGCCTGCTGTTCTCGGCCGATGACATCAGGAAGAACGTCAAGGTGCTATCCGGTGGCGAGAAGGGCC
GCATGATCTGGGGCAAGCTGATGCTGGGCCGCCATAACGTGCTGGCGCTGGACGAGCCGACTAACCACATGGACATGGAA
TCGATCGAGTCGATGCAGATCGCGCTGGACAAGTTTACCGGCACGCTGATCTTCGTTTCGCACGACCGCGAGTTCGTGAG
CGGCCTGGCCACGCGCGTGATCGAAGTGCGTACCGATGGCACGCTGACCGATTACCTCGGCACGTATGACGAGTACCTGC
AGTCGCAGGGTATCGACGGCTGA

Upstream 100 bases:

>100_bases
CTGCCGGGTTCTCCCATGAACCGGGGCGCATCGACGGCGCACCGTTCCGGCAAGCCAGGCGCACAGGCGCCATACCCCGT
TTCCAGACAAGGTTCCAGAC

Downstream 100 bases:

>100_bases
TCGTCGGGCATCCTGACAGCGCAAAGGCCGCCTCCGGGCGGCCTTTGCGTTTGTTGCGCCAGCGTTTCCTTAGATCCCCT
TGTCCGCCTCGATCGCCTCG

Product: ABC transporter related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLESSAGNVMLEPGIRLGKLRQDQFAYEDMR
VLDVVMMGHTEMWAAAQERDAIYANPEATDEDYMKAAELEAKYAEYDGYTAEARAGELLLGVGIPTSQHQGPMSDVAPGW
KLRVLLAQALFSNPDVLLLDEPTNNLDINTIRWLETVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
MEASMQARERQMAANARAKERISELQDFVRRFSANKSKARQATSRAKQIEKIKVEDIKPSSRQNPFIRFEFEKKLHNLAV
EVEGVTKTYDRKIINNLSLAIQAGERVAIIGENGAGKTTLLRSLLNGAVQTGVQRGVEVDRGTVKWAENANVGYMPQDTY
EEFPEDRDVMDWMSQWTQAGDDETSLRGTLGRLLFSADDIRKNVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
SIESMQIALDKFTGTLIFVSHDREFVSGLATRVIEVRTDGTLTDYLGTYDEYLQSQGIDG

Sequences:

>Translated_540_residues
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLESSAGNVMLEPGIRLGKLRQDQFAYEDMR
VLDVVMMGHTEMWAAAQERDAIYANPEATDEDYMKAAELEAKYAEYDGYTAEARAGELLLGVGIPTSQHQGPMSDVAPGW
KLRVLLAQALFSNPDVLLLDEPTNNLDINTIRWLETVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
MEASMQARERQMAANARAKERISELQDFVRRFSANKSKARQATSRAKQIEKIKVEDIKPSSRQNPFIRFEFEKKLHNLAV
EVEGVTKTYDRKIINNLSLAIQAGERVAIIGENGAGKTTLLRSLLNGAVQTGVQRGVEVDRGTVKWAENANVGYMPQDTY
EEFPEDRDVMDWMSQWTQAGDDETSLRGTLGRLLFSADDIRKNVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
SIESMQIALDKFTGTLIFVSHDREFVSGLATRVIEVRTDGTLTDYLGTYDEYLQSQGIDG
>Mature_540_residues
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLESSAGNVMLEPGIRLGKLRQDQFAYEDMR
VLDVVMMGHTEMWAAAQERDAIYANPEATDEDYMKAAELEAKYAEYDGYTAEARAGELLLGVGIPTSQHQGPMSDVAPGW
KLRVLLAQALFSNPDVLLLDEPTNNLDINTIRWLETVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
MEASMQARERQMAANARAKERISELQDFVRRFSANKSKARQATSRAKQIEKIKVEDIKPSSRQNPFIRFEFEKKLHNLAV
EVEGVTKTYDRKIINNLSLAIQAGERVAIIGENGAGKTTLLRSLLNGAVQTGVQRGVEVDRGTVKWAENANVGYMPQDTY
EEFPEDRDVMDWMSQWTQAGDDETSLRGTLGRLLFSADDIRKNVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
SIESMQIALDKFTGTLIFVSHDREFVSGLATRVIEVRTDGTLTDYLGTYDEYLQSQGIDG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=545, Percent_Identity=31.9266055045872, Blast_Score=255, Evalue=7e-68,
Organism=Homo sapiens, GI27881506, Length=543, Percent_Identity=30.5709023941068, Blast_Score=242, Evalue=8e-64,
Organism=Homo sapiens, GI10947137, Length=543, Percent_Identity=30.5709023941068, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI69354671, Length=534, Percent_Identity=27.9026217228464, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI10947135, Length=534, Percent_Identity=27.9026217228464, Blast_Score=175, Evalue=9e-44,
Organism=Escherichia coli, GI1787041, Length=540, Percent_Identity=67.037037037037, Blast_Score=754, Evalue=0.0,
Organism=Escherichia coli, GI1789751, Length=535, Percent_Identity=32.3364485981308, Blast_Score=271, Evalue=9e-74,
Organism=Escherichia coli, GI1787182, Length=548, Percent_Identity=31.5693430656934, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI2367384, Length=531, Percent_Identity=29.5668549905838, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=27.0386266094421, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI145693107, Length=533, Percent_Identity=23.2645403377111, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788165, Length=194, Percent_Identity=27.8350515463918, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788761, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=25.7281553398058, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=543, Percent_Identity=31.1233885819521, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17555318, Length=541, Percent_Identity=28.6506469500924, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17559834, Length=549, Percent_Identity=28.0510018214936, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI115533592, Length=211, Percent_Identity=27.4881516587678, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=541, Percent_Identity=29.0203327171904, Blast_Score=223, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6321121, Length=557, Percent_Identity=28.5457809694794, Blast_Score=216, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6323278, Length=433, Percent_Identity=24.7113163972286, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6325030, Length=426, Percent_Identity=26.056338028169, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=434, Percent_Identity=23.963133640553, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24642252, Length=544, Percent_Identity=28.6764705882353, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI18859989, Length=544, Percent_Identity=28.6764705882353, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24666836, Length=542, Percent_Identity=29.8892988929889, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24641342, Length=549, Percent_Identity=29.5081967213115, Blast_Score=216, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60450; Mature: 60450

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLESSAGNVML
CCCCCEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEE
EPGIRLGKLRQDQFAYEDMRVLDVVMMGHTEMWAAAQERDAIYANPEATDEDYMKAAELE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
AKYAEYDGYTAEARAGELLLGVGIPTSQHQGPMSDVAPGWKLRVLLAQALFSNPDVLLLD
HHHHHCCCEECCCCCCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEE
EPTNNLDINTIRWLETVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
CCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCHHH
MEASMQARERQMAANARAKERISELQDFVRRFSANKSKARQATSRAKQIEKIKVEDIKPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCC
SRQNPFIRFEFEKKLHNLAVEVEGVTKTYDRKIINNLSLAIQAGERVAIIGENGAGKTTL
CCCCCEEEEEHHHHHCCEEEEEECCHHHHHHHHHHCCEEEEECCCEEEEEECCCCCHHHH
LRSLLNGAVQTGVQRGVEVDRGTVKWAENANVGYMPQDTYEEFPEDRDVMDWMSQWTQAG
HHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCC
DDETSLRGTLGRLLFSADDIRKNVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
CCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEECCCCEEEECCCCCCCCHH
SIESMQIALDKFTGTLIFVSHDREFVSGLATRVIEVRTDGTLTDYLGTYDEYLQSQGIDG
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLESSAGNVML
CCCCCEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEE
EPGIRLGKLRQDQFAYEDMRVLDVVMMGHTEMWAAAQERDAIYANPEATDEDYMKAAELE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
AKYAEYDGYTAEARAGELLLGVGIPTSQHQGPMSDVAPGWKLRVLLAQALFSNPDVLLLD
HHHHHCCCEECCCCCCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEE
EPTNNLDINTIRWLETVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
CCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCHHH
MEASMQARERQMAANARAKERISELQDFVRRFSANKSKARQATSRAKQIEKIKVEDIKPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCC
SRQNPFIRFEFEKKLHNLAVEVEGVTKTYDRKIINNLSLAIQAGERVAIIGENGAGKTTL
CCCCCEEEEEHHHHHCCEEEEEECCHHHHHHHHHHCCEEEEECCCEEEEEECCCCCHHHH
LRSLLNGAVQTGVQRGVEVDRGTVKWAENANVGYMPQDTYEEFPEDRDVMDWMSQWTQAG
HHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCC
DDETSLRGTLGRLLFSADDIRKNVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
CCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEECCCCEEEECCCCCCCCHH
SIESMQIALDKFTGTLIFVSHDREFVSGLATRVIEVRTDGTLTDYLGTYDEYLQSQGIDG
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]