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The map label for this gene is yngJ [H]

Identifier: 73541258

GI number: 73541258

Start: 1688723

End: 1689895

Strand: Direct

Name: yngJ [H]

Synonym: Reut_A1568

Alternate gene names: 73541258

Gene position: 1688723-1689895 (Clockwise)

Preceding gene: 73541257

Following gene: 73541259

Centisome position: 44.36

GC content: 69.99

Gene sequence:

>1173_bases
ATGGACTTTTCCCATTCCGTCGAACAGCAGATGATTCGCGACAGCGCGCGGGACTATCTCGCCGCACACAGCGATTCCGC
AGCGGTGCGGCGTGTGACCGAAGCCGGCCCGGCCCATGACGACGCGCTGTGGCGCGCGATGGCCGGCGAGCTTGGCTGGT
GCGGCATCGCGCTGCCCGAAGCCGTGGGCGGCGCCGGCCTGGGTGCGCCCGGACTGGTGCTGCTGCAGGAACAGCTCGGC
CAGCGCCTTGCGTGCGTGCCGTTCTGGTCCACGGTTTGCGTGGCAGCACCGCTGCTGCAGGCCAGTCTCGGTCCGCGCGG
CAGCGCGCAATGGCTGGAACGGCTGGCCTGCGGCGAGATCCGTGCCGCCGTGGTGTTGCCGGACGATGGCGGCTGGCGGT
ATGACCGCGTTGCCGTCACCGCACAGGCGGGCGCGGACGGCTTCGTGCTGCATGGAAATGCCGCACAGGTGGCCGATGCC
GCCGGCGCGGACTGGCTGCTGGTGCCGGCGCAGCTGGAGGATGGCAGCCCCGCGTTGTTCCTGCTGGAGCCCGTCGCCTT
CGCAGGCGATGCACGCTTCTCGCTGCAGCCGCTCGATACGCTCGACCGCACTCGGACGATGGCCGCACTACGGCTGGACG
GGCTGCCCGTCAGTGCCGACGCCTTGCTCGCACGCGGCGACGCCGCCGCGCAGGGCCTGGCCCACGCCTGGTGGCACGGC
AAGCTGATGCTCGCAGCGGAACAGCTTGGCGCGGCGCAGCAATGCCTGGACCTGACCGTTGCCTACGCGTCGGAACGTAT
TCAGTTCGGCCGCGCCATCGCCTCGTTCCAGGCAGTGAAGCACCGCTGCGCGCAGATGATGGTGCTGATCGAAGCGGCAC
GGTCCGCGGTGTATGGCGCGGCCAACGCATGGGATGACGAGGATTCGGCCCGTGCCCGTCCCGACATCGCCGCGGCCTCG
ATCGCGGCCGACGACGCGTTGCGCTTCTGCGCACAGGAGGCTGTCCAGCTCCATGGCGGGGTCGGCTTCACCTGGGAATA
CGACCCCCAGCTCTATTTCAAGCGCGCGCAGGCGGCCAGCCACTGGCTCGGCGGGGCGGGCGTGGCACTCGATTACATCG
CCGATGTTTCCCAAGACGCGGATAGCGAGCCGGGCGCGGGGAGGACAGCATGA

Upstream 100 bases:

>100_bases
CACGCTGGCAACCGGCGGAACTCGGCACGACGGTGGGCGAACTGCTGGCCCAGGCGCACGCGCCGCAGTCGGTCTACGGC
GCGGCCTGAGCGCGACGGCC

Downstream 100 bases:

>100_bases
ACACGAACGAAGACGCGGCATTTCGTGCCGAGGTAGCGGGGTGGATGTCCGCCAATCTGGCCGGAGAGTTCGCCTGCCTG
CAACACCGCGGCGGGCCCGG

Product: Acyl-CoA dehydrogenase, C-terminal

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MDFSHSVEQQMIRDSARDYLAAHSDSAAVRRVTEAGPAHDDALWRAMAGELGWCGIALPEAVGGAGLGAPGLVLLQEQLG
QRLACVPFWSTVCVAAPLLQASLGPRGSAQWLERLACGEIRAAVVLPDDGGWRYDRVAVTAQAGADGFVLHGNAAQVADA
AGADWLLVPAQLEDGSPALFLLEPVAFAGDARFSLQPLDTLDRTRTMAALRLDGLPVSADALLARGDAAAQGLAHAWWHG
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLIEAARSAVYGAANAWDDEDSARARPDIAAAS
IAADDALRFCAQEAVQLHGGVGFTWEYDPQLYFKRAQAASHWLGGAGVALDYIADVSQDADSEPGAGRTA

Sequences:

>Translated_390_residues
MDFSHSVEQQMIRDSARDYLAAHSDSAAVRRVTEAGPAHDDALWRAMAGELGWCGIALPEAVGGAGLGAPGLVLLQEQLG
QRLACVPFWSTVCVAAPLLQASLGPRGSAQWLERLACGEIRAAVVLPDDGGWRYDRVAVTAQAGADGFVLHGNAAQVADA
AGADWLLVPAQLEDGSPALFLLEPVAFAGDARFSLQPLDTLDRTRTMAALRLDGLPVSADALLARGDAAAQGLAHAWWHG
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLIEAARSAVYGAANAWDDEDSARARPDIAAAS
IAADDALRFCAQEAVQLHGGVGFTWEYDPQLYFKRAQAASHWLGGAGVALDYIADVSQDADSEPGAGRTA
>Mature_390_residues
MDFSHSVEQQMIRDSARDYLAAHSDSAAVRRVTEAGPAHDDALWRAMAGELGWCGIALPEAVGGAGLGAPGLVLLQEQLG
QRLACVPFWSTVCVAAPLLQASLGPRGSAQWLERLACGEIRAAVVLPDDGGWRYDRVAVTAQAGADGFVLHGNAAQVADA
AGADWLLVPAQLEDGSPALFLLEPVAFAGDARFSLQPLDTLDRTRTMAALRLDGLPVSADALLARGDAAAQGLAHAWWHG
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLIEAARSAVYGAANAWDDEDSARARPDIAAAS
IAADDALRFCAQEAVQLHGGVGFTWEYDPQLYFKRAQAASHWLGGAGVALDYIADVSQDADSEPGAGRTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=386, Percent_Identity=23.5751295336788, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI226958412, Length=367, Percent_Identity=24.7956403269755, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI226958414, Length=328, Percent_Identity=25.3048780487805, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4557233, Length=340, Percent_Identity=25.5882352941176, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4557231, Length=330, Percent_Identity=24.8484848484848, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI187960098, Length=330, Percent_Identity=24.8484848484848, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4501857, Length=368, Percent_Identity=22.0108695652174, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=383, Percent_Identity=24.8041775456919, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=339, Percent_Identity=25.6637168141593, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=317, Percent_Identity=24.6056782334385, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=26.1484098939929, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=339, Percent_Identity=25.0737463126844, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=331, Percent_Identity=25.3776435045317, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=323, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=25.668449197861, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24666513, Length=338, Percent_Identity=26.3313609467456, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646207, Length=338, Percent_Identity=24.8520710059172, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355753, Length=317, Percent_Identity=25.8675078864353, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41066; Mature: 41066

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSHSVEQQMIRDSARDYLAAHSDSAAVRRVTEAGPAHDDALWRAMAGELGWCGIALPE
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEECHH
AVGGAGLGAPGLVLLQEQLGQRLACVPFWSTVCVAAPLLQASLGPRGSAQWLERLACGEI
HHCCCCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
RAAVVLPDDGGWRYDRVAVTAQAGADGFVLHGNAAQVADAAGADWLLVPAQLEDGSPALF
EEEEEEECCCCCEEEEEEEEEECCCCCEEEECCHHHHHHCCCCCEEEEEEECCCCCCEEE
LLEPVAFAGDARFSLQPLDTLDRTRTMAALRLDGLPVSADALLARGDAAAQGLAHAWWHG
EEECHHHCCCCCEECCCHHHHHHHHHHHHEEECCCCCCHHHHHHCCCHHHHHHHHHHHCC
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLIEAARSAVYGA
CCEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANAWDDEDSARARPDIAAASIAADDALRFCAQEAVQLHGGVGFTWEYDPQLYFKRAQAAS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
HWLGGAGVALDYIADVSQDADSEPGAGRTA
HHCCCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDFSHSVEQQMIRDSARDYLAAHSDSAAVRRVTEAGPAHDDALWRAMAGELGWCGIALPE
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEECHH
AVGGAGLGAPGLVLLQEQLGQRLACVPFWSTVCVAAPLLQASLGPRGSAQWLERLACGEI
HHCCCCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
RAAVVLPDDGGWRYDRVAVTAQAGADGFVLHGNAAQVADAAGADWLLVPAQLEDGSPALF
EEEEEEECCCCCEEEEEEEEEECCCCCEEEECCHHHHHHCCCCCEEEEEEECCCCCCEEE
LLEPVAFAGDARFSLQPLDTLDRTRTMAALRLDGLPVSADALLARGDAAAQGLAHAWWHG
EEECHHHCCCCCEECCCHHHHHHHHHHHHEEECCCCCCHHHHHHCCCHHHHHHHHHHHCC
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLIEAARSAVYGA
CCEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANAWDDEDSARARPDIAAASIAADDALRFCAQEAVQLHGGVGFTWEYDPQLYFKRAQAAS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
HWLGGAGVALDYIADVSQDADSEPGAGRTA
HHCCCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]