| Definition | Ralstonia eutropha JMP134 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007347 |
| Length | 3,806,533 |
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The map label for this gene is gno [H]
Identifier: 73541103
GI number: 73541103
Start: 1526215
End: 1526997
Strand: Direct
Name: gno [H]
Synonym: Reut_A1409
Alternate gene names: 73541103
Gene position: 1526215-1526997 (Clockwise)
Preceding gene: 73541102
Following gene: 73541104
Centisome position: 40.09
GC content: 66.16
Gene sequence:
>783_bases ATGCGTACCATCCAGCAACTATTTGACCTGAAGGGCCGTACCGCGCTCGTGACCGGCGGTTCGCGCGGGCTTGGCCTGCA GATTGCCGAAGCACTGGGCGAGCAAGGTGCGCGCGTGGTGCTTTCCGCGCGCAAGGCCGACGAACTGCAGGCCGCGCAGG CACACCTGAAAGCGCGCGGCATCGAGGCCGACTGGATCGCCGCCGACGGCGCACAGGAAGCCGATATCGCGCGCCTTGCC GACGAAGCACTGGCGAAGCTCGGCCACATCGACATCCTCGTCAACAATGCCGGCGCTACCTGGGGCGCTCCCGCCGAAGA CCACCCGGTCGAAGCCTGGGACAAGGTCATGAACCTGAACATCCGCGGCCTGTTCCTGTTGACGCAGCGCATCGGCAAGC TGTCGATGATTCCGCGCCGCTACGGCCGCATCATCAACGTGGCATCGATTGCCGGTCTCGCCGGCAACCCGCCGGGGTCG ATGGAAACCATTGCCTACAACACCTCCAAGGGTGCCGTGGTCAACTTCACGCGCACGCTGGCGGGCGAGTGGGGCGAGCA CAACATCACCGTCAATGCGCTGGCGCCGGGCTTCTTCCCGTCGAAGATGACCAAGGGCTCGCTCGATCGCCTGGGCGTGG ATGCCATGTGCGAAGGCGTGCCGCTGCACCGCCTTGGCGACGACGAAGACCTGAAGGGCGCCGCGCTGCTGTTCGCGAGC GACGCGGGCAAGCACATTACCGGCCAGATCCTGGCCGTGGACGGTGGCGTCAGCGCAGTCTGA
Upstream 100 bases:
>100_bases GCTACGCTGGACCGCACCACGCTGGATATGCAGGACGCCTGGTTCTGACCCGCGCCGCTATCCGTGTCCACGACATCGAG GAACATCAGGGAACCCAATC
Downstream 100 bases:
>100_bases TCGCATGGTCTAATGGCGGGTGGCTGCGCCTGGCGTGGCGCCCGTCTCATTGAACCTGACAAGACCATGACGCAACACAA CGGATTCCCGAACCGTATTC
Product: gluconate 5-dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 260; Mature: 260
Protein sequence:
>260_residues MRTIQQLFDLKGRTALVTGGSRGLGLQIAEALGEQGARVVLSARKADELQAAQAHLKARGIEADWIAADGAQEADIARLA DEALAKLGHIDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQRIGKLSMIPRRYGRIINVASIAGLAGNPPGS METIAYNTSKGAVVNFTRTLAGEWGEHNITVNALAPGFFPSKMTKGSLDRLGVDAMCEGVPLHRLGDDEDLKGAALLFAS DAGKHITGQILAVDGGVSAV
Sequences:
>Translated_260_residues MRTIQQLFDLKGRTALVTGGSRGLGLQIAEALGEQGARVVLSARKADELQAAQAHLKARGIEADWIAADGAQEADIARLA DEALAKLGHIDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQRIGKLSMIPRRYGRIINVASIAGLAGNPPGS METIAYNTSKGAVVNFTRTLAGEWGEHNITVNALAPGFFPSKMTKGSLDRLGVDAMCEGVPLHRLGDDEDLKGAALLFAS DAGKHITGQILAVDGGVSAV >Mature_260_residues MRTIQQLFDLKGRTALVTGGSRGLGLQIAEALGEQGARVVLSARKADELQAAQAHLKARGIEADWIAADGAQEADIARLA DEALAKLGHIDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQRIGKLSMIPRRYGRIINVASIAGLAGNPPGS METIAYNTSKGAVVNFTRTLAGEWGEHNITVNALAPGFFPSKMTKGSLDRLGVDAMCEGVPLHRLGDDEDLKGAALLFAS DAGKHITGQILAVDGGVSAV
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=33.7349397590361, Blast_Score=125, Evalue=5e-29, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=31.1538461538462, Blast_Score=110, Evalue=9e-25, Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=32.258064516129, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=32.4110671936759, Blast_Score=108, Evalue=7e-24, Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=32.0158102766798, Blast_Score=107, Evalue=9e-24, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=30.46875, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI33667109, Length=213, Percent_Identity=33.8028169014084, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=31.4176245210728, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=31.8897637795276, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=27.9527559055118, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=33.8709677419355, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI20149619, Length=215, Percent_Identity=30.6976744186047, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI7705855, Length=199, Percent_Identity=33.1658291457286, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=29.6577946768061, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI210032110, Length=203, Percent_Identity=29.5566502463054, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI4503817, Length=213, Percent_Identity=31.4553990610329, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=29.6610169491525, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI209862901, Length=207, Percent_Identity=27.0531400966184, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI19923983, Length=207, Percent_Identity=27.0531400966184, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI40254986, Length=225, Percent_Identity=29.7777777777778, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=25.5905511811024, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI7706318, Length=215, Percent_Identity=31.6279069767442, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI226371731, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI157739938, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI142976729, Length=210, Percent_Identity=28.0952380952381, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI83715985, Length=264, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4504505, Length=215, Percent_Identity=30.6976744186047, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4557649, Length=198, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI109715829, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=32.1782178217822, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=33.59375, Blast_Score=148, Evalue=4e-37, Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=34.1176470588235, Blast_Score=144, Evalue=6e-36, Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=34.5098039215686, Blast_Score=134, Evalue=4e-33, Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=35.7976653696498, Blast_Score=134, Evalue=6e-33, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=32.9411764705882, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=33.6032388663968, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=29.3877551020408, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=30.7086614173228, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=29.0836653386454, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=27.8625954198473, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.5193798449612, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=30.8108108108108, Blast_Score=68, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=33.8709677419355, Blast_Score=127, Evalue=6e-30, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=34.4, Blast_Score=125, Evalue=1e-29, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=35.3846153846154, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=31.7343173431734, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=29.8892988929889, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=31.1111111111111, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=33.0855018587361, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=32.089552238806, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=28.8389513108614, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=29.1044776119403, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=29.2134831460674, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=29.8039215686275, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=32.156862745098, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=31.2, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=28.4644194756554, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=31.25, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=25.6505576208178, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=28.1021897810219, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=29.0566037735849, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=28.90625, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=27.8195488721804, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=28.6792452830189, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=27.6679841897233, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=29.9610894941634, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=31, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.4681647940075, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=28.6245353159851, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=32.1608040201005, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=27.6363636363636, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=30.1980198019802, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=27.5, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17555612, Length=208, Percent_Identity=33.1730769230769, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71997099, Length=256, Percent_Identity=26.5625, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17558006, Length=215, Percent_Identity=29.3023255813954, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17568967, Length=258, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17558628, Length=199, Percent_Identity=30.6532663316583, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=209, Percent_Identity=29.1866028708134, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=32.5581395348837, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=33.4645669291339, Blast_Score=118, Evalue=3e-27, Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=30.9803921568627, Blast_Score=117, Evalue=6e-27, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=31.7647058823529, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=33.203125, Blast_Score=114, Evalue=7e-26, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=29.7619047619048, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=30.5882352941176, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI21358495, Length=203, Percent_Identity=30.5418719211823, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=32.1608040201005, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=32.1608040201005, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI28574402, Length=201, Percent_Identity=32.3383084577114, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24584744, Length=201, Percent_Identity=32.3383084577114, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=29.1187739463602, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI17737361, Length=263, Percent_Identity=27.7566539923954, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI21357673, Length=200, Percent_Identity=29, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24640442, Length=202, Percent_Identity=29.2079207920792, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI18859837, Length=209, Percent_Identity=31.1004784688995, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI20129347, Length=222, Percent_Identity=27.027027027027, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007236, Length=239, Percent_Identity=28.8702928870293, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24641232, Length=214, Percent_Identity=29.9065420560748, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27347; Mature: 27347
Theoretical pI: Translated: 6.52; Mature: 6.52
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRTIQQLFDLKGRTALVTGGSRGLGLQIAEALGEQGARVVLSARKADELQAAQAHLKARG CCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC IEADWIAADGAQEADIARLADEALAKLGHIDILVNNAGATWGAPAEDHPVEAWDKVMNLN CCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCC IRGLFLLTQRIGKLSMIPRRYGRIINVASIAGLAGNPPGSMETIAYNTSKGAVVNFTRTL CHHHHHHHHHHCHHHHCHHHHCCEEEHHHHCCCCCCCCCCCEEEEEECCCCEEEEEHHHH AGEWGEHNITVNALAPGFFPSKMTKGSLDRLGVDAMCEGVPLHRLGDDEDLKGAALLFAS CCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCCEEEEEEC DAGKHITGQILAVDGGVSAV CCCCCEEEEEEEECCCCCCC >Mature Secondary Structure MRTIQQLFDLKGRTALVTGGSRGLGLQIAEALGEQGARVVLSARKADELQAAQAHLKARG CCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC IEADWIAADGAQEADIARLADEALAKLGHIDILVNNAGATWGAPAEDHPVEAWDKVMNLN CCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCC IRGLFLLTQRIGKLSMIPRRYGRIINVASIAGLAGNPPGSMETIAYNTSKGAVVNFTRTL CHHHHHHHHHHCHHHHCHHHHCCEEEHHHHCCCCCCCCCCCEEEEEECCCCEEEEEHHHH AGEWGEHNITVNALAPGFFPSKMTKGSLDRLGVDAMCEGVPLHRLGDDEDLKGAALLFAS CCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCCEEEEEEC DAGKHITGQILAVDGGVSAV CCCCCEEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]