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The map label for this gene is clpX [H]

Identifier: 73541075

GI number: 73541075

Start: 1488600

End: 1489877

Strand: Direct

Name: clpX [H]

Synonym: Reut_A1381

Alternate gene names: 73541075

Gene position: 1488600-1489877 (Clockwise)

Preceding gene: 73541074

Following gene: 73541076

Centisome position: 39.11

GC content: 59.78

Gene sequence:

>1278_bases
ATGGCGGAAAAAAAAGGTTCATCCAGCGAAAAGCTTCTCTACTGCTCCTTCTGCGGCAAGAGCCAGCATGAAGTGAAGAA
GCTGATTGCCGGCCCGTCGGTGTTCATCTGCGACGAATGCATCGACCTGTGCAACGAAATCATCCGCGACGAAGCCACTG
CGTCCGAGAAGGATGCGGCTGCGGCCACCCGTTCCGACCTGCCCACACCGCATGAAATCCGCGAAAGCCTGGACCAGTAT
GTGATCGGGCAGGAGCAGGCCAAGAAGATTCTGGCCGTGGCGGTGTACAACCATTACAAGCGCCTCAAGCACCTCGGCAA
GAAGGACGACGTCGAGCTCTCGAAGAGCAATATCCTGCTGATCGGCCCCACCGGTTCGGGAAAGACGCTGCTGGCCCAGA
CGCTGGCGCGCCTGCTCAACGTGCCGTTCGTGATCGCGGACGCGACCACGCTGACCGAAGCAGGCTATGTCGGCGAGGAT
GTCGAGAACATCATCCAGAAGCTGCTGCAGAACTGCAATTACGAGGTCGAGAAGGCGCAGCGCGGTATTGTCTACATCGA
CGAAATCGACAAGATCTCGCGCAAGTCGGACAACCCGTCGATCACGCGCGATGTCTCGGGCGAGGGCGTCCAGCAGGCAC
TGCTCAAGCTGATCGAAGGCACCATGGCATCGGTGCCGCCGCAAGGTGGCCGCAAGCATCCAAACCAGGACTTCCTGCAG
GTCGACACCACGAACATCCTGTTCATTTGCGGTGGCGCGTTCGATGGCCTCGAGAAGGTCATCATGCAGCGCTCGGACAA
GACTGGCATCGGTTTTGCTGCGCAGGTGCAAAGCAAGGAAGAACGCGAAGTCAGCGAAGTGCTGCCGCAGACCGAACCGG
AAGACCTGATCAAGTTCGGCCTGATTCCCGAACTGATCGGCCGCCTGCCGGTCGTGGCTACGCTGGCCAAGCTCGACGAA
ACCGCGCTGGTGCAGATCCTGATCGAGCCGAAGAACGCGCTGGTCAAGCAGTACCAGAAGCTGCTGGCGATGGAAGGCGT
GGAACTGGAAATCCGCCCTGCGGCACTGTCGGCGATCGCGCGCAAGGCGATCCGTCGCAAGACGGGTGCGCGTGGATTGC
GTTCCATCCTGGAGCAATCGCTGATGGACGTTATGTACGACCTGCCGAACTACAAGGGCGTGCAAAAAGTGGTCATCGAC
GAGAGCACCATCAACGGAGACGCCCCGCCGCTGCTGATGTACGAGGAACAGCAGCCGAAGGTGTCAGGCTCCAACTGA

Upstream 100 bases:

>100_bases
CGCCGGTTGGGCAAATTGTTTTGGCGTATGATGCGTTAGAAGCGTACTCCTGCGGCGCTCCCTGTACCGCAATGCGCACA
CTGCTAAGTGACTGATTCCT

Downstream 100 bases:

>100_bases
CGCGAGCGCTGTCCGGGTGAAGAGGTCAAAATCCCATGGCAGCCAGCCAGAAAGGCCGTTCGCGTAGAAGCGAGCGGCTT
TTTTTGTTTATTTCAACCGA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MAEKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEATASEKDAAAATRSDLPTPHEIRESLDQY
VIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGED
VENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFGLIPELIGRLPVVATLAKLDE
TALVQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIARKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVID
ESTINGDAPPLLMYEEQQPKVSGSN

Sequences:

>Translated_425_residues
MAEKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEATASEKDAAAATRSDLPTPHEIRESLDQY
VIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGED
VENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFGLIPELIGRLPVVATLAKLDE
TALVQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIARKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVID
ESTINGDAPPLLMYEEQQPKVSGSN
>Mature_424_residues
AEKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEATASEKDAAAATRSDLPTPHEIRESLDQYV
IGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQV
DTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFGLIPELIGRLPVVATLAKLDET
ALVQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIARKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVIDE
STINGDAPPLLMYEEQQPKVSGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=326, Percent_Identity=51.2269938650307, Blast_Score=313, Evalue=3e-85,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=73.5576923076923, Blast_Score=616, Evalue=1e-178,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=47, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988663, Length=389, Percent_Identity=42.4164524421594, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71982908, Length=296, Percent_Identity=46.6216216216216, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=314, Percent_Identity=44.9044585987261, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=44.578313253012, Blast_Score=192, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6319704, Length=448, Percent_Identity=40.4017857142857, Blast_Score=285, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=46.8553459119497, Blast_Score=288, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=46.8553459119497, Blast_Score=287, Evalue=8e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46697; Mature: 46566

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEATASEKDAA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHH
AATRSDLPTPHEIRESLDQYVIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILL
HHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
IGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFG
EECCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHH
LIPELIGRLPVVATLAKLDETALVQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIA
HHHHHHCCHHHHHHHHHHCHHHEEHEEECCHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
RKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVIDESTINGDAPPLLMYEEQQPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCC
VSGSN
CCCCC
>Mature Secondary Structure 
AEKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEATASEKDAA
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHH
AATRSDLPTPHEIRESLDQYVIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILL
HHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
IGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFG
EECCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHH
LIPELIGRLPVVATLAKLDETALVQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIA
HHHHHHCCHHHHHHHHHHCHHHEEHEEECCHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
RKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVIDESTINGDAPPLLMYEEQQPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCC
VSGSN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA