BacMap

Definition	Ralstonia eutropha JMP134 chromosome 1, complete sequence.
Accession	NC_007347
Length	3,806,533

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The map label for this gene is phbB [H]

Identifier: 73541043

GI number: 73541043

Start: 1450575

End: 1451315

Strand: Direct

Name: phbB [H]

Synonym: Reut_A1349

Alternate gene names: 73541043

Gene position: 1450575-1451315 (Clockwise)

Preceding gene: 73541042

Following gene: 73541044

Centisome position: 38.11

GC content: 62.62

Gene sequence:

>741_bases
ATGACTCAGCGCATTGCATATGTGACCGGCGGTATGGGCGGCATCGGAACCGCGATCTGCCAACGTCTCGCCAAGGATGG
CTTTCGCGTGGTAGCGGGCTGCGGCCCGAACTCACCGCGCCGCGAGCGGTGGATCGAGCAGCAGAAGGCGCTCGGCTTCG
ACTTCGTTGCCTCCGAAGGCAACGTGGCCGACTGGGACTCGACCAAGACTGCGTTCGACAAGGTCAAGGCCGAAGTCGGC
GAGGTTGATGTGCTGATCAACAATGCAGGCATCACGCGCGACGTGGTGTTCCGCAAGATGACGCGCGCCGACTGGGACGC
GGTGATCGACACCAACCTGACCTCGCTGTTCAACGTGACCAAGCAGGTCATCGACGGCATGGTCGATCGTGGCTGGGGTC
GCATCGTCAATATCTCGTCGGTGAACGGGCAGAAGGGCCAGTTCGGCCAGACCAACTACTCCACCGCCAAGGCCGGCCTG
CACGGCTTTACCATGGCTCTGGCACAGGAAGTGGCGACGAAGGGTGTGACGGTGAACACGGTTTCGCCGGGCTACATCGC
CACCGACATGGTCAAGGCTATCCGTCAGGACGTGCTGGACAAGATCGTGGGCACCATCCCGGTCAAGCGCCTGGGTGAGC
CGTCGGAAATCGCGTCCATCTGCGCGTGGCTGTCGTCCGATGAATCGGGCTTCTCCACTGGTGCGGACTTCTCGCTGAAC
GGCGGCCTGCACATGGGCTGA

Upstream 100 bases:

>100_bases
TGTGGCGCTGGCGGTCGAGCGCAATTAAAGGGATATGCCTGTCCGCGCGACCGTTCGCGTGGCCGGGCGAAGATAACGAA
GAGCCAATCAAGGAGCAGAC

Downstream 100 bases:

>100_bases
TTGACAATGCATACGCGCGGGCGCACCGTTTTTGCGGTGCAGCCAGCGCGGTGCACAACCGGTTTGCGCGGACGCTTTGC
GGGCTCTTCGGGGCCCGCAA

Product: acetyacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRRERWIEQQKALGFDFVASEGNVADWDSTKTAFDKVKAEVG
EVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGL
HGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIVGTIPVKRLGEPSEIASICAWLSSDESGFSTGADFSLN
GGLHMG

Sequences:

>Translated_246_residues
MTQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRRERWIEQQKALGFDFVASEGNVADWDSTKTAFDKVKAEVG
EVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGL
HGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIVGTIPVKRLGEPSEIASICAWLSSDESGFSTGADFSLN
GGLHMG
>Mature_245_residues
TQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRRERWIEQQKALGFDFVASEGNVADWDSTKTAFDKVKAEVGE
VDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLH
GFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIVGTIPVKRLGEPSEIASICAWLSSDESGFSTGADFSLNG
GLHMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=36, Blast_Score=150, Evalue=7e-37,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=35.3658536585366, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.2834645669291, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI4504505, Length=246, Percent_Identity=31.3008130081301, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=30.4, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=29.3877551020408, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=30.7086614173228, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.968253968254, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=28.0632411067194, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=31.1004784688995, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=27.8225806451613, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI66933014, Length=183, Percent_Identity=29.5081967213115, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=27.3092369477912, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=24.6861924686192, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=29.8507462686567, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI59889578, Length=216, Percent_Identity=28.7037037037037, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7657478, Length=208, Percent_Identity=29.3269230769231, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI150247226, Length=192, Percent_Identity=30.2083333333333, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI40548397, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI214010158, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI214010156, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI22758144, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI226371731, Length=197, Percent_Identity=30.4568527918782, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4557649, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI22507405, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI19743808, Length=194, Percent_Identity=29.3814432989691, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=30.1980198019802, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=28.804347826087, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=42.5101214574899, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=35.0597609561753, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=30.672268907563, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.9917355371901, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=30.4878048780488, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=28.2786885245902, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.5081967213115, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=29.6296296296296, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=30.6010928961749, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.5, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=26.8774703557312, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=26.8, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786701, Length=205, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=24.5136186770428, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=41.7004048582996, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=37.3983739837398, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=31.8725099601594, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=34.6774193548387, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30.8, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=29.5275590551181, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.9595141700405, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.5546558704453, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=31.7708333333333, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=31.7708333333333, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=29.0816326530612, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=250, Percent_Identity=28.4, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=27.7992277992278, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=29.0836653386454, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=29.1187739463602, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=28.7313432835821, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=28.2868525896414, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.2, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=27.6752767527675, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=27.6363636363636, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=29.1828793774319, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=243, Percent_Identity=28.8065843621399, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=244, Percent_Identity=24.1803278688525, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=241, Percent_Identity=27.3858921161826, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=245, Percent_Identity=28.9795918367347, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=27.037037037037, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=249, Percent_Identity=28.5140562248996, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=25.5, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=252, Percent_Identity=32.5396825396825, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=25.0980392156863, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=27.5, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=35.1020408163265, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=32.4110671936759, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=33.0645161290323, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=31.2252964426877, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=33.203125, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=31.0077519379845, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=30.327868852459, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=27.9352226720648, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859837, Length=232, Percent_Identity=31.8965517241379, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=33.7278106508876, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641232, Length=217, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640442, Length=203, Percent_Identity=30.0492610837438, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364494, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648693, Length=204, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355889, Length=204, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=27.810650887574, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=29.7029702970297, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641388, Length=203, Percent_Identity=31.5270935960591, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571387, Length=198, Percent_Identity=28.7878787878788, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581726, Length=145, Percent_Identity=26.8965517241379, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=26.8041237113402, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26342; Mature: 26211

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRRERWIEQQKALGFDFVASEG
CCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCC
NVADWDSTKTAFDKVKAEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVT
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIATDMVKAIRQDVLDKIVGTIPVKRLGEPSEIASICAWLSSDESGFSTGADFSLN
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEC
GGLHMG
CCCCCC
>Mature Secondary Structure 
TQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRRERWIEQQKALGFDFVASEG
CCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCC
NVADWDSTKTAFDKVKAEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVT
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIATDMVKAIRQDVLDKIVGTIPVKRLGEPSEIASICAWLSSDESGFSTGADFSLN
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEC
GGLHMG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]