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The map label for this gene is cat1 [H]

Identifier: 73540984

GI number: 73540984

Start: 1377459

End: 1378976

Strand: Direct

Name: cat1 [H]

Synonym: Reut_A1290

Alternate gene names: 73540984

Gene position: 1377459-1378976 (Clockwise)

Preceding gene: 73540981

Following gene: 73540987

Centisome position: 36.19

GC content: 64.49

Gene sequence:

>1518_bases
ATGTACAAGGAACGCATTCGCCTGCCGCGGCTGCTCGACAAGGTGGTCTCGGCCGACGTGGCCGCCGAGCTTATCCGCGA
TGGCATGACAGTGGGCATGAGCGGCTTCACCCGGGCAGGCGACTGCAAGGAAGTGCCATTTGCGCTGGCGCGCCGCGCCG
CCACCGAGCCGCTGCGCATCACGCTGATGACCGGCGCATCGCTCGGCAACGACATCGACAAGGTGCTGGCGCAGGCCGAT
GTGATCGCGCGCCGGCTGCCGTTCCAGTCCGATGAGACGCTGCGCCGCAAGATCAACGCGGGCGAGGTCATGTTCATCGA
TCAGCATCTGTCTGAAACGGTCGAGCAATTGCGCTCCGGCCAGATTGCCCCGGTGGACGTAGCGGTGGTCGAAGCGGTGG
CGATCACGGAGCAGGGCGGCATCGTGCCCAGCACGTCGGTCGGCAACTCGGCGAGCTTTGCCATGCTGGCACGCAAGGTG
ATCGTCGAGATCAACATGAACATGCCGCTCGCGCTCGAAGGTTTCCATGACATCTACTTCCCGGTGCAGCGCCCGTACCG
GCAGCCCATTCCGCTGATCTCCGCCGAGCAGCGCATCGGCCTGCCGTATATCCCGATCGATCCCGAAAAGATTGCCGCCA
TCGTTATCACCGGCAAGGACGACAGCCCGTCCAACGCGCTGCCGCCCGACGAAGGCACGCGTGATATTGCGGGACATCTG
AGTACATTCCTGGATCGCGAAGTGCGCGCCGGACGACTGACGCCGTCGCTGCAGCCGCTGCAGGCCGGCATTGGCACGAT
CTCGAACGCGGTGCTGCACGGCCTGATCGACTCGCCGTTCCACGACCTGAAGATGTACTCGGAGGTGCTGCAGGACAGCA
CGATCGAGTTGCTCGATTCGGGCCGGCTTGCGTTCGCATCGGCCTCGTCGGTGACACTGTCACGGTCGGTCTACCAGCAT
TTCCTGGCCAACCTGGAGCGGTACCGCTCGCGCCTGGTGCTGCGGCCGCAGGAGATCAGCAACCATCCGGAGATCTTGCG
CCGGCTCGGGCTGATCACCATCAACACCGCGCTCGAGTGCGACATCTACGGCAACGTCAATTCGACGCATGTCGGCGGCA
CGCACATGATGAACGGCATCGGCGGCTCCGGCGACTTCGCTCGCAACGCGCATCTGTCGGTGTTCGTGACCAAGTCGGTG
GCCAAGGGCGGGGATATCTCCAGCATCGTGCCGATGGTCTCGCATGTGGACCACACCGAGCATGATGTCGACATCATCGT
GACCGAACACGGTCTGGCCGACTTGCGTGGCCTTGCACCGCGCGAGCGTGCCAGGCAGATCATCGACAACTGCGCTGACC
CGGCCTACCGCGATGTGCTGGGTGACTACTTCCGCCGCGCCAGCCGCCTGGGCGGTCAGACGCCGCACTTGCTCGAAGAA
GCGCTGTCCTGGCACGTGCGATATCGCGATCGCGGCACGATGCGCGAGTCCGTGCCCCAGCATGCCATGGCTGCCTGA

Upstream 100 bases:

>100_bases
GTGGGAATGTATGCGCGTGGCTACACTGCTTTTCCAACCCCGGCGCTAAAGCCAAGGGGCGCACGGGCGGACCGGAACCG
CCCGGCAACCGGAGATGTTG

Downstream 100 bases:

>100_bases
TAGCCGGCTTCCTTCAGCGCCATAAGCAAACAGCCCGCAAATGCGGGCTGTCTTGTTTCCGTGGCCTGCTCTGGAAAGCA
GGCCTAAGGGGCTTACTGCG

Product: Acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MYKERIRLPRLLDKVVSADVAAELIRDGMTVGMSGFTRAGDCKEVPFALARRAATEPLRITLMTGASLGNDIDKVLAQAD
VIARRLPFQSDETLRRKINAGEVMFIDQHLSETVEQLRSGQIAPVDVAVVEAVAITEQGGIVPSTSVGNSASFAMLARKV
IVEINMNMPLALEGFHDIYFPVQRPYRQPIPLISAEQRIGLPYIPIDPEKIAAIVITGKDDSPSNALPPDEGTRDIAGHL
STFLDREVRAGRLTPSLQPLQAGIGTISNAVLHGLIDSPFHDLKMYSEVLQDSTIELLDSGRLAFASASSVTLSRSVYQH
FLANLERYRSRLVLRPQEISNHPEILRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVTKSV
AKGGDISSIVPMVSHVDHTEHDVDIIVTEHGLADLRGLAPRERARQIIDNCADPAYRDVLGDYFRRASRLGGQTPHLLEE
ALSWHVRYRDRGTMRESVPQHAMAA

Sequences:

>Translated_505_residues
MYKERIRLPRLLDKVVSADVAAELIRDGMTVGMSGFTRAGDCKEVPFALARRAATEPLRITLMTGASLGNDIDKVLAQAD
VIARRLPFQSDETLRRKINAGEVMFIDQHLSETVEQLRSGQIAPVDVAVVEAVAITEQGGIVPSTSVGNSASFAMLARKV
IVEINMNMPLALEGFHDIYFPVQRPYRQPIPLISAEQRIGLPYIPIDPEKIAAIVITGKDDSPSNALPPDEGTRDIAGHL
STFLDREVRAGRLTPSLQPLQAGIGTISNAVLHGLIDSPFHDLKMYSEVLQDSTIELLDSGRLAFASASSVTLSRSVYQH
FLANLERYRSRLVLRPQEISNHPEILRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVTKSV
AKGGDISSIVPMVSHVDHTEHDVDIIVTEHGLADLRGLAPRERARQIIDNCADPAYRDVLGDYFRRASRLGGQTPHLLEE
ALSWHVRYRDRGTMRESVPQHAMAA
>Mature_505_residues
MYKERIRLPRLLDKVVSADVAAELIRDGMTVGMSGFTRAGDCKEVPFALARRAATEPLRITLMTGASLGNDIDKVLAQAD
VIARRLPFQSDETLRRKINAGEVMFIDQHLSETVEQLRSGQIAPVDVAVVEAVAITEQGGIVPSTSVGNSASFAMLARKV
IVEINMNMPLALEGFHDIYFPVQRPYRQPIPLISAEQRIGLPYIPIDPEKIAAIVITGKDDSPSNALPPDEGTRDIAGHL
STFLDREVRAGRLTPSLQPLQAGIGTISNAVLHGLIDSPFHDLKMYSEVLQDSTIELLDSGRLAFASASSVTLSRSVYQH
FLANLERYRSRLVLRPQEISNHPEILRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVTKSV
AKGGDISSIVPMVSHVDHTEHDVDIIVTEHGLADLRGLAPRERARQIIDNCADPAYRDVLGDYFRRASRLGGQTPHLLEE
ALSWHVRYRDRGTMRESVPQHAMAA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=485, Percent_Identity=45.5670103092784, Blast_Score=416, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17538151, Length=385, Percent_Identity=24.9350649350649, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563853, Length=242, Percent_Identity=28.099173553719, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319456, Length=516, Percent_Identity=43.4108527131783, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55345; Mature: 55345

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKERIRLPRLLDKVVSADVAAELIRDGMTVGMSGFTRAGDCKEVPFALARRAATEPLRI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEE
TLMTGASLGNDIDKVLAQADVIARRLPFQSDETLRRKINAGEVMFIDQHLSETVEQLRSG
EEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHCC
QIAPVDVAVVEAVAITEQGGIVPSTSVGNSASFAMLARKVIVEINMNMPLALEGFHDIYF
CCCCCHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEECCCHHHCC
PVQRPYRQPIPLISAEQRIGLPYIPIDPEKIAAIVITGKDDSPSNALPPDEGTRDIAGHL
CCCCCCCCCCCCCCCHHHCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHH
STFLDREVRAGRLTPSLQPLQAGIGTISNAVLHGLIDSPFHDLKMYSEVLQDSTIELLDS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHC
GRLAFASASSVTLSRSVYQHFLANLERYRSRLVLRPQEISNHPEILRRLGLITINTALEC
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCEEEECEEEE
DIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVTKSVAKGGDISSIVPMVSHVDHTE
EEECCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCC
HDVDIIVTEHGLADLRGLAPRERARQIIDNCADPAYRDVLGDYFRRASRLGGQTPHLLEE
CCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHVRYRDRGTMRESVPQHAMAA
HHHHHHHCCCCCCHHHHCCHHHHCC
>Mature Secondary Structure
MYKERIRLPRLLDKVVSADVAAELIRDGMTVGMSGFTRAGDCKEVPFALARRAATEPLRI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEE
TLMTGASLGNDIDKVLAQADVIARRLPFQSDETLRRKINAGEVMFIDQHLSETVEQLRSG
EEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHCC
QIAPVDVAVVEAVAITEQGGIVPSTSVGNSASFAMLARKVIVEINMNMPLALEGFHDIYF
CCCCCHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEECCCHHHCC
PVQRPYRQPIPLISAEQRIGLPYIPIDPEKIAAIVITGKDDSPSNALPPDEGTRDIAGHL
CCCCCCCCCCCCCCCHHHCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHH
STFLDREVRAGRLTPSLQPLQAGIGTISNAVLHGLIDSPFHDLKMYSEVLQDSTIELLDS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHC
GRLAFASASSVTLSRSVYQHFLANLERYRSRLVLRPQEISNHPEILRRLGLITINTALEC
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCEEEECEEEE
DIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVTKSVAKGGDISSIVPMVSHVDHTE
EEECCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCC
HDVDIIVTEHGLADLRGLAPRERARQIIDNCADPAYRDVLGDYFRRASRLGGQTPHLLEE
CCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHVRYRDRGTMRESVPQHAMAA
HHHHHHHCCCCCCHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]