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The map label for this gene is ihfA [H]

Identifier: 73540975

GI number: 73540975

Start: 1368082

End: 1368498

Strand: Direct

Name: ihfA [H]

Synonym: Reut_A1281

Alternate gene names: 73540975

Gene position: 1368082-1368498 (Clockwise)

Preceding gene: 73540974

Following gene: 73540976

Centisome position: 35.94

GC content: 63.31

Gene sequence:

>417_bases
ATGAAAGATCGAGACGCGAACTCCATGACCGCAGCAGCTTTGGGCGAGATGAGCGACCGGCAGGCTTCCTCCCGCGACGA
CTCCATGCCGGAAAACCGCGCCGCCGAGGTGCCGACGCTGACCAAGGCCGAACTCGCCGAAATGCTGTTCGACCAGGTCG
GCCTGAACAAACGCGAATCGAAAGACATGGTCGAAGCCTTCTTCGACGTCATTCGGGAAGCGCTGGAGCAGGGCGACAGC
GTCAAGCTCTCCGGCTTCGGCAACTTCCAGTTGCGCGACAAGCCGCAGCGCCCGGGCCGCAATCCGAAGACCGGTGAAGT
CATTCCCATCACCGCGCGCCGCGTCGTGACATTCCACGCAAGCCAGAAGCTCAAGAGCCTGGTGGAAGAGCGTGCGGGCC
TGGACGTGCCGGGCTGA

Upstream 100 bases:

>100_bases
AGGCTCGCTTGCGCGGCTGACCACCAGCACATACCACAGACAGGGCGCCCGGGCAGTGCACCCGGGCGGATCGCCAGACA
GAATTCCTTGAGCGATCGAC

Downstream 100 bases:

>100_bases
CCGAAGGGGCCTCACCCCAACGGCGGATTGCTTGGCGCAGCAGGCGTCTGTATGCTTCATGGCGCGCTGATCCACGCGCC
AACTCGAACCGGCCGGCATG

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKDRDANSMTAAALGEMSDRQASSRDDSMPENRAAEVPTLTKAELAEMLFDQVGLNKRESKDMVEAFFDVIREALEQGDS
VKLSGFGNFQLRDKPQRPGRNPKTGEVIPITARRVVTFHASQKLKSLVEERAGLDVPG

Sequences:

>Translated_138_residues
MKDRDANSMTAAALGEMSDRQASSRDDSMPENRAAEVPTLTKAELAEMLFDQVGLNKRESKDMVEAFFDVIREALEQGDS
VKLSGFGNFQLRDKPQRPGRNPKTGEVIPITARRVVTFHASQKLKSLVEERAGLDVPG
>Mature_138_residues
MKDRDANSMTAAALGEMSDRQASSRDDSMPENRAAEVPTLTKAELAEMLFDQVGLNKRESKDMVEAFFDVIREALEQGDS
VKLSGFGNFQLRDKPQRPGRNPKTGEVIPITARRVVTFHASQKLKSLVEERAGLDVPG

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1788005, Length=90, Percent_Identity=73.3333333333333, Blast_Score=135, Evalue=7e-34,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=35.5555555555556, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=33.7078651685393, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 15249; Mature: 15249

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRDANSMTAAALGEMSDRQASSRDDSMPENRAAEVPTLTKAELAEMLFDQVGLNKRES
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
KDMVEAFFDVIREALEQGDSVKLSGFGNFQLRDKPQRPGRNPKTGEVIPITARRVVTFHA
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHH
SQKLKSLVEERAGLDVPG
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKDRDANSMTAAALGEMSDRQASSRDDSMPENRAAEVPTLTKAELAEMLFDQVGLNKRES
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
KDMVEAFFDVIREALEQGDSVKLSGFGNFQLRDKPQRPGRNPKTGEVIPITARRVVTFHA
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHH
SQKLKSLVEERAGLDVPG
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]