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The map label for this gene is gmhB [H]

Identifier: 73540429

GI number: 73540429

Start: 784083

End: 784649

Strand: Direct

Name: gmhB [H]

Synonym: Reut_A0723

Alternate gene names: 73540429

Gene position: 784083-784649 (Clockwise)

Preceding gene: 73540428

Following gene: 73540430

Centisome position: 20.6

GC content: 62.79

Gene sequence:

>567_bases
ATGGGACAGCCGGCACTGTTCCTTGATCGCGATGGTGTGATCAACGTTGATACCGGTTACGTGCATTGCCCCGAAGATTG
CCGGTTTGTCGACGGCATTTTCGATCTGGTACGCCGGGCCAATGCCGCAGGTATGGCCGTGTGTGTGGTGACCAACCAGG
CTGGTATTGCGCGCGGCTACTACGACGAAGCGCAGTTCCAGCATTTCACGACCTGGATGCTCGCCCGTTTCGAGGAAGAG
GGCGCGCATATCGACAAGGTCTATCACTGTCCACATCATCCGATGGCGGGTCAGGGCGAATATCTGAAGGCGTGCCAGTG
CCGCAAGCCGGCGCCGGGCATGCTCCTGGCCGCCAGGGATGCACTGGGGCTGGACATGGGGCGATCGGTCATGGTCGGCG
ATACCCTCACGGACATGCAAGCCGCGGCGTCCGCGAGTGTGGGTACGCGATGGCTGGTGCCACATGGCGATGCGGCGCTT
GCCGAGGCGGGGCGTTCGGCCGGCTGCTGCGTGGCGGAGCATCTGTCAGAGATCGATCCGACCAGAGCATTGCGCCTGAA
GGCCTGA

Upstream 100 bases:

>100_bases
TGGGTGCCTTTCTCGGTGTGACCGATTTCATCGACATCGGCATTCCGGAGGACTACCAGACCGCGCAAACCAAGGTCCCA
GCGCTGATCGAGGCCATGTA

Downstream 100 bases:

>100_bases
CAGCTCGCCGGACAATTGCAGGTGCCCCGCATTGCGCGCTCTAGAACCCTGCCATTGGCGTGGATATCAGAATGCAAATA
ACCTTTTCGATCGTCAGCCA

Product: D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MGQPALFLDRDGVINVDTGYVHCPEDCRFVDGIFDLVRRANAAGMAVCVVTNQAGIARGYYDEAQFQHFTTWMLARFEEE
GAHIDKVYHCPHHPMAGQGEYLKACQCRKPAPGMLLAARDALGLDMGRSVMVGDTLTDMQAAASASVGTRWLVPHGDAAL
AEAGRSAGCCVAEHLSEIDPTRALRLKA

Sequences:

>Translated_188_residues
MGQPALFLDRDGVINVDTGYVHCPEDCRFVDGIFDLVRRANAAGMAVCVVTNQAGIARGYYDEAQFQHFTTWMLARFEEE
GAHIDKVYHCPHHPMAGQGEYLKACQCRKPAPGMLLAARDALGLDMGRSVMVGDTLTDMQAAASASVGTRWLVPHGDAAL
AEAGRSAGCCVAEHLSEIDPTRALRLKA
>Mature_187_residues
GQPALFLDRDGVINVDTGYVHCPEDCRFVDGIFDLVRRANAAGMAVCVVTNQAGIARGYYDEAQFQHFTTWMLARFEEEG
AHIDKVYHCPHHPMAGQGEYLKACQCRKPAPGMLLAARDALGLDMGRSVMVGDTLTDMQAAASASVGTRWLVPHGDAALA
EAGRSAGCCVAEHLSEIDPTRALRLKA

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=164, Percent_Identity=51.8292682926829, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI87082027, Length=160, Percent_Identity=27.5, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20306; Mature: 20175

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQPALFLDRDGVINVDTGYVHCPEDCRFVDGIFDLVRRANAAGMAVCVVTNQAGIARGY
CCCCCEEEECCCEEEECCCEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCC
YDEAQFQHFTTWMLARFEEEGAHIDKVYHCPHHPMAGQGEYLKACQCRKPAPGMLLAARD
CCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEECC
ALGLDMGRSVMVGDTLTDMQAAASASVGTRWLVPHGDAALAEAGRSAGCCVAEHLSEIDP
HHCCCCCCEEEECCCHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCCHHHHHHHHCCC
TRALRLKA
CCEEEECC
>Mature Secondary Structure 
GQPALFLDRDGVINVDTGYVHCPEDCRFVDGIFDLVRRANAAGMAVCVVTNQAGIARGY
CCCCEEEECCCEEEECCCEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCC
YDEAQFQHFTTWMLARFEEEGAHIDKVYHCPHHPMAGQGEYLKACQCRKPAPGMLLAARD
CCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEECC
ALGLDMGRSVMVGDTLTDMQAAASASVGTRWLVPHGDAALAEAGRSAGCCVAEHLSEIDP
HHCCCCCCEEEECCCHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCCHHHHHHHHCCC
TRALRLKA
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11108008; 11206551; 11258796 [H]