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The map label for this gene is apaH [H]

Identifier: 73540417

GI number: 73540417

Start: 770646

End: 771479

Strand: Reverse

Name: apaH [H]

Synonym: Reut_A0711

Alternate gene names: 73540417

Gene position: 771479-770646 (Counterclockwise)

Preceding gene: 73540441

Following gene: 73540409

Centisome position: 20.27

GC content: 64.51

Gene sequence:

>834_bases
GTGTCTTATAAATCATATTTCGCGGTTGGCGATCTCCAGGGATGCGCCGGTTCTTTTAACGAACTGCTTGGCAAACTTCC
ACCGGACGGTGGCCTCCGCCTTGTCGGCGACCTGATTAACCGCGGCCCCGCCTCACTCCAGACGCTCCGTACCGTCCGCG
CTCTGGGCGACCGTGCAGAAACCGTGCTGGGCAACCACGACATCCACGCCCTGGCCGCGGCTGCAGGCGTGCGTAAGAAC
GGCAAATCCGACACCTTGCAGGACATCCTTACCGCGCCCGACCGTGACGACTTGCTAACCTGGCTGCGCCACCGCCCACT
CGCCCTCCTCGAGGACAACTTCCTGCTCATCCACGCCGGCGTCCTGCCCCAATGGTCCCCCGAGCAAGTTATCGACCTCG
CCCACGAAGTCGAAGAACAACTGCAAGGCCCGAACTGGCAAGGTTTCCTGGCCGACATCTTTGGCAACGCTGCCGACCGC
TGGCACGACGGCCTGCGGGGGATCGAACGTCACCGCGTGGTCATCAACGCCCTGACCCGGCTGCGCTATTGCACCGCCGA
TGGAGTGATGGACTTCAAGACCAAGGAGGGGCTCGGCAAGGCACCGGCCGGCTTCATGCCATGGTTCGACGTGCCGGGAC
GCCGAACCGAGAATGTCACCGTGGTGTGCGGGCACTGGTCGACGCTCGGCCTGGTAATGCGCCCGAACCTGATGGCGCTC
GATACCGGTTGCGTCTGGGGCGGCAAACTGACCGCCGCGCGCCTCGCCGCGGATCCGGCCGCGAGGACGCTGATCCAGGT
CGAGTGCCCCCAATATTGTGACCCGCTCGCCTGA

Upstream 100 bases:

>100_bases
CTTCTTTTTGTAGCCTGTTGTAACGATCCGGCTGTTAGGCGGTCACTTCTCTACAAATAGCGACGATTTTTCCCCGCTGC
TCAGCGGACACAGGCAAAAA

Downstream 100 bases:

>100_bases
CGCTGTCGTCCCTGCCACGGCGGGGACGACAGCCCAGATCAGCTCGTGGCAGTCGGCGCCGGGGTTCCGGCGAAATCCTC
GCTATCCTGATTGCGCCGGA

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSYKSYFAVGDLQGCAGSFNELLGKLPPDGGLRLVGDLINRGPASLQTLRTVRALGDRAETVLGNHDIHALAAAAGVRKN
GKSDTLQDILTAPDRDDLLTWLRHRPLALLEDNFLLIHAGVLPQWSPEQVIDLAHEVEEQLQGPNWQGFLADIFGNAADR
WHDGLRGIERHRVVINALTRLRYCTADGVMDFKTKEGLGKAPAGFMPWFDVPGRRTENVTVVCGHWSTLGLVMRPNLMAL
DTGCVWGGKLTAARLAADPAARTLIQVECPQYCDPLA

Sequences:

>Translated_277_residues
MSYKSYFAVGDLQGCAGSFNELLGKLPPDGGLRLVGDLINRGPASLQTLRTVRALGDRAETVLGNHDIHALAAAAGVRKN
GKSDTLQDILTAPDRDDLLTWLRHRPLALLEDNFLLIHAGVLPQWSPEQVIDLAHEVEEQLQGPNWQGFLADIFGNAADR
WHDGLRGIERHRVVINALTRLRYCTADGVMDFKTKEGLGKAPAGFMPWFDVPGRRTENVTVVCGHWSTLGLVMRPNLMAL
DTGCVWGGKLTAARLAADPAARTLIQVECPQYCDPLA
>Mature_276_residues
SYKSYFAVGDLQGCAGSFNELLGKLPPDGGLRLVGDLINRGPASLQTLRTVRALGDRAETVLGNHDIHALAAAAGVRKNG
KSDTLQDILTAPDRDDLLTWLRHRPLALLEDNFLLIHAGVLPQWSPEQVIDLAHEVEEQLQGPNWQGFLADIFGNAADRW
HDGLRGIERHRVVINALTRLRYCTADGVMDFKTKEGLGKAPAGFMPWFDVPGRRTENVTVVCGHWSTLGLVMRPNLMALD
TGCVWGGKLTAARLAADPAARTLIQVECPQYCDPLA

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=254, Percent_Identity=41.7322834645669, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30277; Mature: 30146

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKSYFAVGDLQGCAGSFNELLGKLPPDGGLRLVGDLINRGPASLQTLRTVRALGDRAE
CCCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TVLGNHDIHALAAAAGVRKNGKSDTLQDILTAPDRDDLLTWLRHRPLALLEDNFLLIHAG
HHHCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCEEEEEEC
VLPQWSPEQVIDLAHEVEEQLQGPNWQGFLADIFGNAADRWHDGLRGIERHRVVINALTR
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LRYCTADGVMDFKTKEGLGKAPAGFMPWFDVPGRRTENVTVVCGHWSTLGLVMRPNLMAL
HHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHCCCEECCCEEEE
DTGCVWGGKLTAARLAADPAARTLIQVECPQYCDPLA
ECCCCCCCCHHHHHHHCCHHHHHEEEEECHHHCCCCC
>Mature Secondary Structure 
SYKSYFAVGDLQGCAGSFNELLGKLPPDGGLRLVGDLINRGPASLQTLRTVRALGDRAE
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TVLGNHDIHALAAAAGVRKNGKSDTLQDILTAPDRDDLLTWLRHRPLALLEDNFLLIHAG
HHHCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCEEEEEEC
VLPQWSPEQVIDLAHEVEEQLQGPNWQGFLADIFGNAADRWHDGLRGIERHRVVINALTR
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LRYCTADGVMDFKTKEGLGKAPAGFMPWFDVPGRRTENVTVVCGHWSTLGLVMRPNLMAL
HHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHCCCEECCCEEEE
DTGCVWGGKLTAARLAADPAARTLIQVECPQYCDPLA
ECCCCCCCCHHHHHHHCCHHHHHEEEEECHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]