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The map label for this gene is pgk [H]

Identifier: 73540265

GI number: 73540265

Start: 605461

End: 606657

Strand: Reverse

Name: pgk [H]

Synonym: Reut_A0559

Alternate gene names: 73540265

Gene position: 606657-605461 (Counterclockwise)

Preceding gene: 73540268

Following gene: 73540264

Centisome position: 15.94

GC content: 66.08

Gene sequence:

>1197_bases
ATGACCTCCGTCCTGCGTCTATCCGACCTCATCTCCCAAGGCAAAATCTCCGGCAAGCGTGTTTTTATCCGCGCCGACAT
GAATGTGCCGCAGGATGACGCCGGCAATATCACCGAGGACACCCGCATCCGCGCTTCGGTGCCGGCCATCGAGGCCTGCC
TGGCTGCTGGCGCCGCCGTGATGGTCACGTCGCACCTGGGCCGCCCGACCGAAGGCGAGTTCAAGCCGGCCGATTCGCTG
GCGCCGATTGCCACGCGCCTGTCCGAACTGCTGGGCAAGCCGGTGAAGCTGGTGCAGAACTGGGTCGATGGCGTGGAGGT
CGCTCCGGGTCAGGTGGTGCTGCTGGAAAACTGCCGCGTGAACAAGGGCGAAAAGAAGAACAGCGACGAACTGGCGCAGA
AGATGGCCAAGCTGTGCGACGTGTACGTCAATGACGCGTTCGGCACCGCTCACCGCGCCGAAGCGACCACGCACGGCATC
GCCAAGTACGCGCCGATCGCCTGCGCCGGCCCGCTGCTGGCCGCCGAGATCGACGCGCTGGGCAAGGCGCTGGGCCAGCC
GGCGCGTCCGCTGGTCGCCATCGTGGCCGGCTCGAAGGTCTCGACCAAGCTGACCATCCTGAAGTCGCTGGCCGACAAGG
TGGACAACCTGATCGTCGGCGGCGGCATCGCCAACACCTTCATGCTGGCCGCCGGCCTGAAGATCGGCAAGTCGCTGGCC
GAAGCCGACCTGGTGGCCGATGCCAAGACCATCATCGACATCATGGCCAAGCGCGGTGCCTCGGTACCCATTCCGGTCGA
CGTCGTGTGCGCCAAGGCGTTCAGCGCCACCGCCGCCGCCACCGTCAAGGACGTCAAGGACGTGGCCGACGACGACATGA
TCCTCGACATCGGGCCGAAGACCGCCGCGCAATTGGCCGACCAGCTCAAGGCTGCCGGTACCATCGTGTGGAACGGCCCG
GTGGGCGTGTTCGAGTTCGACCAGTTCGGCAACGGCACCAAGGTGCTGGCCGAAGCCATCGCCGATTCCAAGGCATTCTC
GATCGCCGGCGGCGGCGACACGCTGGCCGCCATCGCCAAGTACGGCATTGCCGACCGCGTGGGCTATATCTCGACCGGCG
GCGGCGCGTTCCTGGAGTTCCTGGAAGGCAAGAAGCTGCCCGCATTCGAAGTGCTGGAGCAACGCGCAGCAGGCTGA

Upstream 100 bases:

>100_bases
GTCGTTGCGCCCGGTCCCAAACCGGCTAAGCAATGACTGCGATCAGGTAAAATGATTGTTTCCCCGAAATTTCAGCGAAA
TCTCGCGCCATCACACCGTC

Downstream 100 bases:

>100_bases
GGCCGCGCTGGCCCGCGTCCGGACAAGGATCCCCCGCCATGACCCGCTCCACCAAGATCGTCGCCACCATCGGCCCCGCT
TCCAGCTCGCTGGAAGTGCT

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTSVLRLSDLISQGKISGKRVFIRADMNVPQDDAGNITEDTRIRASVPAIEACLAAGAAVMVTSHLGRPTEGEFKPADSL
APIATRLSELLGKPVKLVQNWVDGVEVAPGQVVLLENCRVNKGEKKNSDELAQKMAKLCDVYVNDAFGTAHRAEATTHGI
AKYAPIACAGPLLAAEIDALGKALGQPARPLVAIVAGSKVSTKLTILKSLADKVDNLIVGGGIANTFMLAAGLKIGKSLA
EADLVADAKTIIDIMAKRGASVPIPVDVVCAKAFSATAAATVKDVKDVADDDMILDIGPKTAAQLADQLKAAGTIVWNGP
VGVFEFDQFGNGTKVLAEAIADSKAFSIAGGGDTLAAIAKYGIADRVGYISTGGGAFLEFLEGKKLPAFEVLEQRAAG

Sequences:

>Translated_398_residues
MTSVLRLSDLISQGKISGKRVFIRADMNVPQDDAGNITEDTRIRASVPAIEACLAAGAAVMVTSHLGRPTEGEFKPADSL
APIATRLSELLGKPVKLVQNWVDGVEVAPGQVVLLENCRVNKGEKKNSDELAQKMAKLCDVYVNDAFGTAHRAEATTHGI
AKYAPIACAGPLLAAEIDALGKALGQPARPLVAIVAGSKVSTKLTILKSLADKVDNLIVGGGIANTFMLAAGLKIGKSLA
EADLVADAKTIIDIMAKRGASVPIPVDVVCAKAFSATAAATVKDVKDVADDDMILDIGPKTAAQLADQLKAAGTIVWNGP
VGVFEFDQFGNGTKVLAEAIADSKAFSIAGGGDTLAAIAKYGIADRVGYISTGGGAFLEFLEGKKLPAFEVLEQRAAG
>Mature_397_residues
TSVLRLSDLISQGKISGKRVFIRADMNVPQDDAGNITEDTRIRASVPAIEACLAAGAAVMVTSHLGRPTEGEFKPADSLA
PIATRLSELLGKPVKLVQNWVDGVEVAPGQVVLLENCRVNKGEKKNSDELAQKMAKLCDVYVNDAFGTAHRAEATTHGIA
KYAPIACAGPLLAAEIDALGKALGQPARPLVAIVAGSKVSTKLTILKSLADKVDNLIVGGGIANTFMLAAGLKIGKSLAE
ADLVADAKTIIDIMAKRGASVPIPVDVVCAKAFSATAAATVKDVKDVADDDMILDIGPKTAAQLADQLKAAGTIVWNGPV
GVFEFDQFGNGTKVLAEAIADSKAFSIAGGGDTLAAIAKYGIADRVGYISTGGGAFLEFLEGKKLPAFEVLEQRAAG

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=412, Percent_Identity=42.4757281553398, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI4505763, Length=425, Percent_Identity=39.0588235294118, Blast_Score=256, Evalue=2e-68,
Organism=Escherichia coli, GI1789294, Length=394, Percent_Identity=62.1827411167513, Blast_Score=480, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17508823, Length=420, Percent_Identity=42.3809523809524, Blast_Score=283, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6319857, Length=424, Percent_Identity=41.0377358490566, Blast_Score=265, Evalue=9e-72,
Organism=Drosophila melanogaster, GI17136394, Length=405, Percent_Identity=40, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24581203, Length=403, Percent_Identity=36.7245657568238, Blast_Score=227, Evalue=1e-59,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 41144; Mature: 41013

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVLRLSDLISQGKISGKRVFIRADMNVPQDDAGNITEDTRIRASVPAIEACLAAGAAV
CCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCHHH
MVTSHLGRPTEGEFKPADSLAPIATRLSELLGKPVKLVQNWVDGVEVAPGQVVLLENCRV
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCEEEEECCCC
NKGEKKNSDELAQKMAKLCDVYVNDAFGTAHRAEATTHGIAKYAPIACAGPLLAAEIDAL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHCCHHHHHHHHHH
GKALGQPARPLVAIVAGSKVSTKLTILKSLADKVDNLIVGGGIANTFMLAAGLKIGKSLA
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHH
EADLVADAKTIIDIMAKRGASVPIPVDVVCAKAFSATAAATVKDVKDVADDDMILDIGPK
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
TAAQLADQLKAAGTIVWNGPVGVFEFDQFGNGTKVLAEAIADSKAFSIAGGGDTLAAIAK
HHHHHHHHHHHCCEEEECCCCCEEEHHCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHH
YGIADRVGYISTGGGAFLEFLEGKKLPAFEVLEQRAAG
HCHHHCCCEEECCHHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TSVLRLSDLISQGKISGKRVFIRADMNVPQDDAGNITEDTRIRASVPAIEACLAAGAAV
CCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCHHH
MVTSHLGRPTEGEFKPADSLAPIATRLSELLGKPVKLVQNWVDGVEVAPGQVVLLENCRV
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCEEEEECCCC
NKGEKKNSDELAQKMAKLCDVYVNDAFGTAHRAEATTHGIAKYAPIACAGPLLAAEIDAL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHCCHHHHHHHHHH
GKALGQPARPLVAIVAGSKVSTKLTILKSLADKVDNLIVGGGIANTFMLAAGLKIGKSLA
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHH
EADLVADAKTIIDIMAKRGASVPIPVDVVCAKAFSATAAATVKDVKDVADDDMILDIGPK
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
TAAQLADQLKAAGTIVWNGPVGVFEFDQFGNGTKVLAEAIADSKAFSIAGGGDTLAAIAK
HHHHHHHHHHHCCEEEECCCCCEEEHHCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHH
YGIADRVGYISTGGGAFLEFLEGKKLPAFEVLEQRAAG
HCHHHCCCEEECCHHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]