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The map label for this gene is ywlC [H]

Identifier: 73540259

GI number: 73540259

Start: 598956

End: 599942

Strand: Reverse

Name: ywlC [H]

Synonym: Reut_A0553

Alternate gene names: 73540259

Gene position: 599942-598956 (Counterclockwise)

Preceding gene: 73540260

Following gene: 73540258

Centisome position: 15.76

GC content: 68.49

Gene sequence:

>987_bases
ATGTCGCGCATGCCCACGGCCGCCGAACTGGACGAAGCCGTCCGCCTGCTGGAGGCCGGCCAGCTGGTCGCCTTTCCCAC
TGAAACCGTCTACGGGCTCGGCGCCGACGCCGAAAGTCCGGAAGCGGTCGCGCGCATCTTCGCGCTCAAGGGCCGGCCGT
CGAACCATCCGGTCATCGTGCATGTGGTTGACGGCGCCGACATCGGCTACTGGGTCGACGAGGTGCCCGAAGCCGCGACA
AAGCTGATCGAAGCGTTCTGGCCGGGCCCGCTCACGCTGATCCTCAAGCGCGCCTCGCACATCCACGCGGCAGTGGCCGG
CGGCCAGGACAGCATCGGACTACGCTGCCCGTCGCACCCCGTCGCGCAGGCACTGCTGTCGCGCTTCAAGCGCGGCCGCG
GCGGCATTGCCGCGCCTTCTGCCAACAAGTTTGGCCAGGTCAGCCCGACCACTGCGCAACACGTGCGCGACGAATTCGGC
GATGCGGTCTATGTGCTGGAAGGCGATGGCGTGGAAGTCGGCATCGAATCGACGATCGTCGATCTTTCAAGGCTCGACCA
GGGCATCGGCCCGGTCCTACTGCGACCGGGTGCGATCACGCCAGCGATGATGGCGAAGGTGCTCGGCGAAGCGCCGCTGC
CGCCTGATGCCGCGGCCCCCCGTGCGTCGGGCACGCTGAAGGCTCACTACGCTCCGCATACCCCGCTGGTGCTGGCTGAC
GCGGCCGAGCTCGCGGCACAACTGCCCTCGCTTGCTGCCGATGCCCGCGTGGCGTGGGTAGGACGTGCCCCGATCGAAGA
TCCGCGCTGCACGTGGGTGCAGGCGCCTGCGGATGCCACCGCCTATGCGCGGGAACTCTACCGACTGCTGCGCAAGCTGG
ACAAGCAGGGCTTCACGCAGCTGGTGTTTGAGCCGCTGCCAGAGGGGCATGAGTGGGCTGGGGTCAGGGATCGGCTGCAG
AGGGCCGCAGCCGCGTTCGGGGGATAG

Upstream 100 bases:

>100_bases
CGAGGCCGCCGCGCAAGCGTTCGATGTCGCTGCGAAGGCGCTGCACATCCCGCTCTGATCCAATCTGACCCTATCCGTCT
CGCCCGCTTCAAGGAACACG

Downstream 100 bases:

>100_bases
GCCTTCCTGGCTCTTCGCCTGAGCAGTACCGACTGCTATGCGGCAGTCCAGAAAGCCCTCCAGCCGTTCGCCAGAAGCGC
CATATACACGCGACACCTCC

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSRMPTAAELDEAVRLLEAGQLVAFPTETVYGLGADAESPEAVARIFALKGRPSNHPVIVHVVDGADIGYWVDEVPEAAT
KLIEAFWPGPLTLILKRASHIHAAVAGGQDSIGLRCPSHPVAQALLSRFKRGRGGIAAPSANKFGQVSPTTAQHVRDEFG
DAVYVLEGDGVEVGIESTIVDLSRLDQGIGPVLLRPGAITPAMMAKVLGEAPLPPDAAAPRASGTLKAHYAPHTPLVLAD
AAELAAQLPSLAADARVAWVGRAPIEDPRCTWVQAPADATAYARELYRLLRKLDKQGFTQLVFEPLPEGHEWAGVRDRLQ
RAAAAFGG

Sequences:

>Translated_328_residues
MSRMPTAAELDEAVRLLEAGQLVAFPTETVYGLGADAESPEAVARIFALKGRPSNHPVIVHVVDGADIGYWVDEVPEAAT
KLIEAFWPGPLTLILKRASHIHAAVAGGQDSIGLRCPSHPVAQALLSRFKRGRGGIAAPSANKFGQVSPTTAQHVRDEFG
DAVYVLEGDGVEVGIESTIVDLSRLDQGIGPVLLRPGAITPAMMAKVLGEAPLPPDAAAPRASGTLKAHYAPHTPLVLAD
AAELAAQLPSLAADARVAWVGRAPIEDPRCTWVQAPADATAYARELYRLLRKLDKQGFTQLVFEPLPEGHEWAGVRDRLQ
RAAAAFGG
>Mature_327_residues
SRMPTAAELDEAVRLLEAGQLVAFPTETVYGLGADAESPEAVARIFALKGRPSNHPVIVHVVDGADIGYWVDEVPEAATK
LIEAFWPGPLTLILKRASHIHAAVAGGQDSIGLRCPSHPVAQALLSRFKRGRGGIAAPSANKFGQVSPTTAQHVRDEFGD
AVYVLEGDGVEVGIESTIVDLSRLDQGIGPVLLRPGAITPAMMAKVLGEAPLPPDAAAPRASGTLKAHYAPHTPLVLADA
AELAAQLPSLAADARVAWVGRAPIEDPRCTWVQAPADATAYARELYRLLRKLDKQGFTQLVFEPLPEGHEWAGVRDRLQR
AAAAFGG

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=181, Percent_Identity=32.5966850828729, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI2367210, Length=159, Percent_Identity=28.9308176100629, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081864, Length=125, Percent_Identity=30.4, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=382, Percent_Identity=31.151832460733, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI78707274, Length=191, Percent_Identity=27.7486910994764, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34715; Mature: 34584

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRMPTAAELDEAVRLLEAGQLVAFPTETVYGLGADAESPEAVARIFALKGRPSNHPVIV
CCCCCCHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCCHHHHHHHHHHCCCCCCCCEEE
HVVDGADIGYWVDEVPEAATKLIEAFWPGPLTLILKRASHIHAAVAGGQDSIGLRCPSHP
EEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
VAQALLSRFKRGRGGIAAPSANKFGQVSPTTAQHVRDEFGDAVYVLEGDGVEVGIESTIV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCEEECHHHHHH
DLSRLDQGIGPVLLRPGAITPAMMAKVLGEAPLPPDAAAPRASGTLKAHYAPHTPLVLAD
HHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEH
AAELAAQLPSLAADARVAWVGRAPIEDPRCTWVQAPADATAYARELYRLLRKLDKQGFTQ
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHH
LVFEPLPEGHEWAGVRDRLQRAAAAFGG
HHHHCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRMPTAAELDEAVRLLEAGQLVAFPTETVYGLGADAESPEAVARIFALKGRPSNHPVIV
CCCCCHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCCHHHHHHHHHHCCCCCCCCEEE
HVVDGADIGYWVDEVPEAATKLIEAFWPGPLTLILKRASHIHAAVAGGQDSIGLRCPSHP
EEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
VAQALLSRFKRGRGGIAAPSANKFGQVSPTTAQHVRDEFGDAVYVLEGDGVEVGIESTIV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCEEECHHHHHH
DLSRLDQGIGPVLLRPGAITPAMMAKVLGEAPLPPDAAAPRASGTLKAHYAPHTPLVLAD
HHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEH
AAELAAQLPSLAADARVAWVGRAPIEDPRCTWVQAPADATAYARELYRLLRKLDKQGFTQ
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHH
LVFEPLPEGHEWAGVRDRLQRAAAAFGG
HHHHCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]