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The map label for this gene is ubiH [H]

Identifier: 73540196

GI number: 73540196

Start: 533050

End: 534288

Strand: Reverse

Name: ubiH [H]

Synonym: Reut_A0490

Alternate gene names: 73540196

Gene position: 534288-533050 (Counterclockwise)

Preceding gene: 73540197

Following gene: 73540195

Centisome position: 14.04

GC content: 69.73

Gene sequence:

>1239_bases
ATGACGCAGGCCGAACCTGAAGTCCGCGACATCGCCATCGTCGGTGGCGGCCCGGTAGGGCTGGCGCTGGCTTGCCAGTT
GCTGCTGGCTACCGACTGGCGCATTACGCTGATCGACGCCGCCACGCCGGCGCGCGCGGCGCGCGACCCGCGCGCCATCG
CGCTGTCCCACGGCAGCCGCCAGTTGCTGGAGCAGATCGGCGCATGGCCCGTCGCCGGCACGGCGATCGAGCACATCCAT
GTCTCGCAGCGGGGGCGTCTTGGTCACGTGAAGCTGCATCATGACGACTACGGGGTGCCGGCGCTGGGCTACGTGGTGCG
CTATGGGGAGTTGTGCAACGTGCTGGAGCGCGCGATCGGCCGCGCCGCGAAGCAGGTAGGCGAATCGCGCCTGCTGCGCG
TGTTCGAAACCCGCATCGACGACCTGCAGCAGGATCCGCTGATCGGCGGCGATTTCGACGGCATCGATGCGATGAGTGGC
GCGGTCCATCTCACTGGCACGGCGACGGACGGCCAGGTAGCGCGCTTTTCCTCACGCATTGCGATCCAGGCTGAAGGCGG
CCTGTTTCACCAGCAGGTCGCGCATGCGGGCCAGGGCTCGCGGCATCGCGACTACCGGCAAACCGCTGTGATCGGCCATG
TTGCGTGCTCGCGCCCGCGCCACGGCTGGGCGTGGGAGCGGTTCACCGAGGAAGGGCCGCTGGCGCTGTTGCCCTATGAC
GAGCACGGCATCGACGGCTACGCGCTCGTCTGGTGCTGCCCGCCCGACCAGGCCGCGCGGCGCATCGCACTGAGCGATGC
GGAGTTCGCGGAGGAGCTTAATGCCGTGTTCGGCGACCGCCTAGGGCGCTTCACGCTGGCTGGCAAGCGCCACGCGTTCC
CGCTCGGGCTCAATGCCGCACCGGTAACGGTCGATGGCCGCATCGCGGCAGTTGGCAATGCCGCCCAGACGCTGCACCCG
GTGGCGGGCCAGGGACTGAACCTGGGCCTTCGCGATGCATTTGCGCTTGCCGATTCCCTGCGTGCGGGCTGCTCGCCGCG
CTCGCTGCAGGCCTTCGCATCGCGCCACAGGCTGGACCGCGCTGTGACCATCGGCGTCACCGACCTGCTGCCGCGCGTGT
TCGGCATCCCGTCCCCGCTGGCCGCGCATGCGCGAGGCGCGTCCCTGGCGGCGCTGGCTTGCGTGTCACCGCTCAAGCAT
GCGCTGGCGCGCCACATGATGTACGGCATGCGCCGGTGA

Upstream 100 bases:

>100_bases
GATGCCTCGGCCGGCAAGTCGCGCTCCGACGCGGTCTGCTGGAAGCGCGGCGCGCAGGCGGAGCCGGCATCGGATATCAA
CACGGACCGGAGTCCCGGCA

Downstream 100 bases:

>100_bases
TCCACAATGACGGGACCGCGACAGCGGCTCCCGCCATGCGCCAGGTAATCTATTCGAGGCATTTTCGGACTTCGCCTCTT
GCTTTGATGCTCAATTCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTQAEPEVRDIAIVGGGPVGLALACQLLLATDWRITLIDAATPARAARDPRAIALSHGSRQLLEQIGAWPVAGTAIEHIH
VSQRGRLGHVKLHHDDYGVPALGYVVRYGELCNVLERAIGRAAKQVGESRLLRVFETRIDDLQQDPLIGGDFDGIDAMSG
AVHLTGTATDGQVARFSSRIAIQAEGGLFHQQVAHAGQGSRHRDYRQTAVIGHVACSRPRHGWAWERFTEEGPLALLPYD
EHGIDGYALVWCCPPDQAARRIALSDAEFAEELNAVFGDRLGRFTLAGKRHAFPLGLNAAPVTVDGRIAAVGNAAQTLHP
VAGQGLNLGLRDAFALADSLRAGCSPRSLQAFASRHRLDRAVTIGVTDLLPRVFGIPSPLAAHARGASLAALACVSPLKH
ALARHMMYGMRR

Sequences:

>Translated_412_residues
MTQAEPEVRDIAIVGGGPVGLALACQLLLATDWRITLIDAATPARAARDPRAIALSHGSRQLLEQIGAWPVAGTAIEHIH
VSQRGRLGHVKLHHDDYGVPALGYVVRYGELCNVLERAIGRAAKQVGESRLLRVFETRIDDLQQDPLIGGDFDGIDAMSG
AVHLTGTATDGQVARFSSRIAIQAEGGLFHQQVAHAGQGSRHRDYRQTAVIGHVACSRPRHGWAWERFTEEGPLALLPYD
EHGIDGYALVWCCPPDQAARRIALSDAEFAEELNAVFGDRLGRFTLAGKRHAFPLGLNAAPVTVDGRIAAVGNAAQTLHP
VAGQGLNLGLRDAFALADSLRAGCSPRSLQAFASRHRLDRAVTIGVTDLLPRVFGIPSPLAAHARGASLAALACVSPLKH
ALARHMMYGMRR
>Mature_411_residues
TQAEPEVRDIAIVGGGPVGLALACQLLLATDWRITLIDAATPARAARDPRAIALSHGSRQLLEQIGAWPVAGTAIEHIHV
SQRGRLGHVKLHHDDYGVPALGYVVRYGELCNVLERAIGRAAKQVGESRLLRVFETRIDDLQQDPLIGGDFDGIDAMSGA
VHLTGTATDGQVARFSSRIAIQAEGGLFHQQVAHAGQGSRHRDYRQTAVIGHVACSRPRHGWAWERFTEEGPLALLPYDE
HGIDGYALVWCCPPDQAARRIALSDAEFAEELNAVFGDRLGRFTLAGKRHAFPLGLNAAPVTVDGRIAAVGNAAQTLHPV
AGQGLNLGLRDAFALADSLRAGCSPRSLQAFASRHRLDRAVTIGVTDLLPRVFGIPSPLAAHARGASLAALACVSPLKHA
LARHMMYGMRR

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=405, Percent_Identity=24.6913580246914, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI32967307, Length=277, Percent_Identity=26.7148014440433, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1789274, Length=420, Percent_Identity=36.4285714285714, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789273, Length=348, Percent_Identity=29.5977011494253, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786883, Length=362, Percent_Identity=32.0441988950276, Blast_Score=102, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19920760, Length=372, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 44154; Mature: 44023

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAEPEVRDIAIVGGGPVGLALACQLLLATDWRITLIDAATPARAARDPRAIALSHGSR
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCEEEECCCHH
QLLEQIGAWPVAGTAIEHIHVSQRGRLGHVKLHHDDYGVPALGYVVRYGELCNVLERAIG
HHHHHHCCCCCCCHHHHEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RAAKQVGESRLLRVFETRIDDLQQDPLIGGDFDGIDAMSGAVHLTGTATDGQVARFSSRI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEEEEECCCCCHHHHHCCEE
AIQAEGGLFHQQVAHAGQGSRHRDYRQTAVIGHVACSRPRHGWAWERFTEEGPLALLPYD
EEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEECCC
EHGIDGYALVWCCPPDQAARRIALSDAEFAEELNAVFGDRLGRFTLAGKRHAFPLGLNAA
CCCCCCEEEEEECCCHHHHHEECCCHHHHHHHHHHHHHHHCCCEEECCCCCCCEECCCCC
PVTVDGRIAAVGNAAQTLHPVAGQGLNLGLRDAFALADSLRAGCSPRSLQAFASRHRLDR
CEEECCEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AVTIGVTDLLPRVFGIPSPLAAHARGASLAALACVSPLKHALARHMMYGMRR
EEEECHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQAEPEVRDIAIVGGGPVGLALACQLLLATDWRITLIDAATPARAARDPRAIALSHGSR
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCEEEECCCHH
QLLEQIGAWPVAGTAIEHIHVSQRGRLGHVKLHHDDYGVPALGYVVRYGELCNVLERAIG
HHHHHHCCCCCCCHHHHEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RAAKQVGESRLLRVFETRIDDLQQDPLIGGDFDGIDAMSGAVHLTGTATDGQVARFSSRI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEEEEECCCCCHHHHHCCEE
AIQAEGGLFHQQVAHAGQGSRHRDYRQTAVIGHVACSRPRHGWAWERFTEEGPLALLPYD
EEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEECCC
EHGIDGYALVWCCPPDQAARRIALSDAEFAEELNAVFGDRLGRFTLAGKRHAFPLGLNAA
CCCCCCEEEEEECCCHHHHHEECCCHHHHHHHHHHHHHHHCCCEEECCCCCCCEECCCCC
PVTVDGRIAAVGNAAQTLHPVAGQGLNLGLRDAFALADSLRAGCSPRSLQAFASRHRLDR
CEEECCEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AVTIGVTDLLPRVFGIPSPLAAHARGASLAALACVSPLKHALARHMMYGMRR
EEEECHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]