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The map label for this gene is oxyR [H]

Identifier: 73540179

GI number: 73540179

Start: 516714

End: 517619

Strand: Direct

Name: oxyR [H]

Synonym: Reut_A0473

Alternate gene names: 73540179

Gene position: 516714-517619 (Clockwise)

Preceding gene: 73540177

Following gene: 73540182

Centisome position: 13.57

GC content: 67.66

Gene sequence:

>906_bases
ATGATCCCTTTCTCATTCCGGCAACTGGAGTACTTCGTGGCGGCTGCCGAGCATGGCAGCATCAGCGCTGCGGCGCGGGC
GCGTCATGTGTCCCAGCCGTCGGTGTCGACGGCCATCGCGCAGCTCGAAGACACGCTGGGCGAGGCGCTGTTTCGCCGGC
AGGTCAGCCGCGGCCTCGAACTCACGCCGGCCGGGCAGCGCCTGCTCGCACGAGCACGCGATATTCTGGCCCTGGCTGCG
GGAATCACCGTCGATGAAGCCGGACAGCAGGGGCTGAGCGGCCGGCTGTCGCTGACCTGCTTTCAGGACCTGGGTCCGTA
CTTCGTCCCCCGCTTGCTGGCGGGCTTCCGGGAGCAGCATCCGGCGGTTTCCATCACGCTGTTCGAGGCGGATCTGGCGG
CAGTCCATCGCACGCTGCAGGCCGGCAAGGCCGAGCTTGCGCTGACGTACGACCTCGGTTTTGACCAGCGCATCGATCGA
TGGATTCTGGCGAGCCTGCCGCCCTACGCGTTGTTGCCTGCGAACCATCGGCGCGCGGGCCAGCGTGATATCAGTCTTGC
GGAACTGGCTGGCGAGCGCCTGATCCTCGAGGACATCGCGCAGACGCGTGAGTATTTCCTATCGCTGTTCTGGGCCCACG
GTCTGCATCCGACGCTGCACCAGTACACGCAGACGTTCGAGATGCAGCGCGGTCTCGTGGCGCATGGATACGGTGTGGCG
CTGTCGTGCACGCGGCCGGCCGGCGACCACAGCTATGACGGGCAACCCATCGCGTGCCTGCCGCTACGCGAGCCCGTGAC
CGGCCAGCGGGTCGTGCTGGCGCGCGCGCAAGCCGTGCGCGCGTCGCCGCTCGCGCAGGCGTTTATCGGATGGATGGTGG
AAAGCGGGCACGCGGCGCCGGTCTGA

Upstream 100 bases:

>100_bases
TGATTTCCATGGCCAGGCTCCGGGGCAGGGACGTGCCCAGTATCGGCAACCTTTATCAATAGGAAAAGCATATATTTCCT
ATGCTGTAGTATAGGAAATC

Downstream 100 bases:

>100_bases
ACCCGATCGCCGCAGCGACAATCAGCGCGGATAGATCGCGCCGAGCACGCGCGGACCGGCGGCGCCGGTGACCGTGGCGA
CATTGCCCGGCAGGCGGAGC

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIPFSFRQLEYFVAAAEHGSISAAARARHVSQPSVSTAIAQLEDTLGEALFRRQVSRGLELTPAGQRLLARARDILALAA
GITVDEAGQQGLSGRLSLTCFQDLGPYFVPRLLAGFREQHPAVSITLFEADLAAVHRTLQAGKAELALTYDLGFDQRIDR
WILASLPPYALLPANHRRAGQRDISLAELAGERLILEDIAQTREYFLSLFWAHGLHPTLHQYTQTFEMQRGLVAHGYGVA
LSCTRPAGDHSYDGQPIACLPLREPVTGQRVVLARAQAVRASPLAQAFIGWMVESGHAAPV

Sequences:

>Translated_301_residues
MIPFSFRQLEYFVAAAEHGSISAAARARHVSQPSVSTAIAQLEDTLGEALFRRQVSRGLELTPAGQRLLARARDILALAA
GITVDEAGQQGLSGRLSLTCFQDLGPYFVPRLLAGFREQHPAVSITLFEADLAAVHRTLQAGKAELALTYDLGFDQRIDR
WILASLPPYALLPANHRRAGQRDISLAELAGERLILEDIAQTREYFLSLFWAHGLHPTLHQYTQTFEMQRGLVAHGYGVA
LSCTRPAGDHSYDGQPIACLPLREPVTGQRVVLARAQAVRASPLAQAFIGWMVESGHAAPV
>Mature_301_residues
MIPFSFRQLEYFVAAAEHGSISAAARARHVSQPSVSTAIAQLEDTLGEALFRRQVSRGLELTPAGQRLLARARDILALAA
GITVDEAGQQGLSGRLSLTCFQDLGPYFVPRLLAGFREQHPAVSITLFEADLAAVHRTLQAGKAELALTYDLGFDQRIDR
WILASLPPYALLPANHRRAGQRDISLAELAGERLILEDIAQTREYFLSLFWAHGLHPTLHQYTQTFEMQRGLVAHGYGVA
LSCTRPAGDHSYDGQPIACLPLREPVTGQRVVLARAQAVRASPLAQAFIGWMVESGHAAPV

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=241, Percent_Identity=31.1203319502075, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789204, Length=294, Percent_Identity=27.891156462585, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787879, Length=249, Percent_Identity=28.9156626506024, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=27.4914089347079, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787530, Length=248, Percent_Identity=26.6129032258064, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=300, Percent_Identity=22.3333333333333, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788887, Length=241, Percent_Identity=26.1410788381743, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787601, Length=148, Percent_Identity=31.7567567567568, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=147, Percent_Identity=34.0136054421769, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=302, Percent_Identity=24.1721854304636, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788297, Length=151, Percent_Identity=32.4503311258278, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32864; Mature: 32864

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPFSFRQLEYFVAAAEHGSISAAARARHVSQPSVSTAIAQLEDTLGEALFRRQVSRGLE
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
LTPAGQRLLARARDILALAAGITVDEAGQQGLSGRLSLTCFQDLGPYFVPRLLAGFREQH
CCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHCC
PAVSITLFEADLAAVHRTLQAGKAELALTYDLGFDQRIDRWILASLPPYALLPANHRRAG
CEEEEEEEHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEECCCCCCCCC
QRDISLAELAGERLILEDIAQTREYFLSLFWAHGLHPTLHQYTQTFEMQRGLVAHGYGVA
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCEE
LSCTRPAGDHSYDGQPIACLPLREPVTGQRVVLARAQAVRASPLAQAFIGWMVESGHAAP
EEECCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
V
C
>Mature Secondary Structure
MIPFSFRQLEYFVAAAEHGSISAAARARHVSQPSVSTAIAQLEDTLGEALFRRQVSRGLE
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
LTPAGQRLLARARDILALAAGITVDEAGQQGLSGRLSLTCFQDLGPYFVPRLLAGFREQH
CCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHCC
PAVSITLFEADLAAVHRTLQAGKAELALTYDLGFDQRIDRWILASLPPYALLPANHRRAG
CEEEEEEEHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEECCCCCCCCC
QRDISLAELAGERLILEDIAQTREYFLSLFWAHGLHPTLHQYTQTFEMQRGLVAHGYGVA
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCEE
LSCTRPAGDHSYDGQPIACLPLREPVTGQRVVLARAQAVRASPLAQAFIGWMVESGHAAP
EEECCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]