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The map label for this gene is erpA [H]

Identifier: 73540177

GI number: 73540177

Start: 515409

End: 515777

Strand: Direct

Name: erpA [H]

Synonym: Reut_A0471

Alternate gene names: 73540177

Gene position: 515409-515777 (Clockwise)

Preceding gene: 73540176

Following gene: 73540179

Centisome position: 13.54

GC content: 59.89

Gene sequence:

>369_bases
ATGAACGCAGTCGCAGAGGCCCCCGTTACCGAGGACGTGCCGGCACCGTTCGTCTTTACCGACAGCGCAGCCGACAAGGT
CAAGCAGCTGATCGAGGAAGAGGGCAATGCCGAGCTGAAGCTGCGCGTGTTCGTGCAGGGCGGCGGCTGCTCTGGCTTCC
AGTATGGCTTCACGTTCGACGAGGAAGTCAACGAAGACGACACCACGATGGTCAAGAACGGCGTGACCTTGCTGATCGAC
TCGATGAGCTACCAGTATCTGGTCGGCGCCGAGATCGACTACAAGGAAGACATCAACGGCGCGCAGTTCGTGATCAAGAA
CCCGAACGCAAGCACCACCTGCGGTTGCGGCTCGTCGTTCTCGGTCTGA

Upstream 100 bases:

>100_bases
TCACGCGCGATACTTTGCCAGAAGCCCTTGAAAACCAAGGGATTCGGCACGATTTTCCAGTAGCGCTTAAAATACAGTCG
TACCTAAACAGGAGAACCCC

Downstream 100 bases:

>100_bases
GGCAACACGTCCCGGCAAAAAGGCGCACCTTCGGGTGCGCTTTTTTTATGCCGGCGTCGCCCGCCACACTACCGGAAACC
AGTCCTCGCGCATCCGCTCG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MNAVAEAPVTEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFDEEVNEDDTTMVKNGVTLLID
SMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV

Sequences:

>Translated_122_residues
MNAVAEAPVTEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFDEEVNEDDTTMVKNGVTLLID
SMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV
>Mature_122_residues
MNAVAEAPVTEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFDEEVNEDDTTMVKNGVTLLID
SMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential) [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=105, Percent_Identity=40.9523809523809, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI52426768, Length=108, Percent_Identity=34.2592592592593, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=60.5263157894737, Blast_Score=155, Evalue=9e-40,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=39.0476190476191, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=108, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=108, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=97, Percent_Identity=38.1443298969072, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24642263, Length=108, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13138; Mature: 13138

Theoretical pI: Translated: 3.78; Mature: 3.78

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVAEAPVTEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFD
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEC
EEVNEDDTTMVKNGVTLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSF
CCCCCCCCEEECCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
SV
CC
>Mature Secondary Structure
MNAVAEAPVTEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFD
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEC
EEVNEDDTTMVKNGVTLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSF
CCCCCCCCEEECCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
SV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA